Elin Yulinah
Departemen Farmasi, Institut Teknologi Bandung

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Antimicrobial Activities of the Ethanol Extracts of Capsicum Fruits with Different Levels of Pungency Soediro Soetarno; Sukrasno Sukrasno; Elin Yulinah; Sylvia Sylvia
Jurnal Matematika & Sains Vol 2, No 2 (1997)
Publisher : Institut Teknologi Bandung

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Abstract

Ethanol extracts of the fruits of three kinds of Capsicum showed similar potencies in their antimicrobial activities against Gram (+) and Gram (-) bacterias, and fungi, although they contained different level of capsaicin. Bioautographic tests demonstrated that capsaicin was the main antimicrobial component. At least two other non-polar components of ethanol extract also contributed in the antimicrobial activity and very likely that these compounds were responsible for the activity toward Pseudomonas aeruginosa.
Aktivitas Antidiabetika Ekstrak Etanol Herba Sambiloto (Andrographis paniculata Nees (Acanthaceae)) Elin Yulinah; Sukrasno Sukrasno; Muna Anom Fitri
Jurnal Matematika & Sains Vol 6, No 1 (2001)
Publisher : Institut Teknologi Bandung

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Abstract

Antidiabetic activity of the ethanol extract of Andrographis paniculata Nees herbs had been tested using glucose tolerance test in rat and alloxan induced diabetic mice. The extract reduced rat blood glucose at the dose of 2.0 g/kg bw but there was no effect observed at dose of 0.50 g/kg bw and 1.0 g/kg bw. It is interesting that the extract at doses 2.1 g/kg bw and 2.8 g/kg bw, and the effect was much lower at 3.5 g/kg bw also showed the capacity to reduce blood glucose level of alloxane induced diabetic mice.
Uji Daya Lekat Mukoadhesif secara In Vitro beberapa Eksipien Polimer Tunggal dan Kombinasinya pada Lambung dan Usus Tikus Teti Indrawati; Goeswin Agoes; Elin Yulinah; Yeyet Cahyati Sumirtapura
Jurnal Matematika & Sains Vol 10, No 2 (2005)
Publisher : Institut Teknologi Bandung

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Abstract

Mucoadhesive strength test of some polymer excipients is importance for development of oral sustain release with mucoadhesive system to enchance bioavailability. Mucoadhesive strength of granules that prepared using single and combination of polymers i.e. from carboxymethylcellulose, gum arabic, and sodium alginate with Metolose 90SH-15.000 (Metolose K-15) and Metolose 90SH-100.000 (Metolose K-100) on rat stomach and intestinal had been determined by bioadhesion and wash off test. Results showed that single polymer and its combination could adhesive to rat stomach and intestine in 5 minuter. The granul prepared using Metolose K-15 and sodium alginat in single and combination form gave the strongest adhesive strength to stomach, while Metolose K-15 and gum arabic in a single form showed the strongest adhesive to intestine. The strongest adhesion to stomach and intestine was the granule combination of sodium alginat and Metolose K-15 (20 : 40) with the amount of granule adhesived to stomach and intestine was 100 % and 88 % respectively.
Efek Antihipertensi dan Hipotensi beberapa Fraksi dari Ekstrak Etanol Umbi Lapis Kucai (Allium schoenoprasum L., Lliliaceae) Irda Fidrianny; Kosasih Padmawinata; Soediro Soetarno; Elin Yulinah
Jurnal Matematika & Sains Vol 8, No 4 (2003)
Publisher : Institut Teknologi Bandung

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Abstract

Hypotensive and antihypertensive effect of fractions of ethanolic extract of “kucai” (Allium schoenoprasum L., Liliaceae) bulb had been tested on male Wistar rats. The ethyl acetate, n-buthanol and aqueous fractions of both fresh and dry bulb had hypotensive and antihypertensive effects. The aqueous fraction of fresh bulb at a dose of 25 mg/kg body weight showed the highest hypotensive and antihypertensive activities. The n-buthanol fraction of dry bulb at a dose of 50 mg/kg body weight showed the highest hypotensive activity. The ethyl acetate fraction of dry bulb at a dose of 50 mg/kg body weight showed the highest antihypertensive activity.