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PENGARUH PEMBERIAN EFEK JINTEN HITAM (NIGELLA SATIVA) TERHADAP APOPTOSIS TERHADAP SEL EPITEKL BRONKIOLUS DAN APOPTOSIS LIMFOSIT T SALURAN NAFAS BRONCHIOLUS PADA MODEL MENCIT ASTHMA Endang Sriwahyuni; IMAMA KHALIS NUR ARIFAH
Saintika Medika Vol. 6 No. 2 (2010): Desember 2010
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.v6i2.1060

Abstract

Abstract Airway remodelling refers to the structural changes that occur in the airway wall in asthma. These is irreversible changes to the airway, with damage of bronchiolus epithelium because the airway epithelium undergoes apoptosis as one of its manifestations. Empirically black seed has been known as bronchial asthma therapy for many years ago. The purpose of the research is to test the effect of black seed (Nigella sativa L.) extract to apoptosis of bronchiolus epithelium and apoptosis of T lymphocytes the airway bronchial asthma on asthma mouse model. Female mice were used in the expeimental laboratory research and allergic mouse model was got by given ovalbumin twice within 3 weeks intraperitoneally and 3 times per week within 6 weeks by inhalation. Black seed extract is given in 3 different dose (0,024 cc/day, 0,048 cc/day and 0,096 cc/day) for 9 weeks. Sample was chosen randomly to share it within 5 group containing 6 mice in every group ; negative control group (without any treatment, n=6), positive control group (sensitizied with ovalbumin, n=6), JH1 group (sensitizied with ovalbumin and treating with first dose of black seed extract, n=6), JH2 group (sensitizied with ovalbumin and treating with second dose of black seed extract, n=6), JH3 group (sensitizied with ovalbumin and treating with third dose of black seed extract, n=6). The parametric that is used in this research is the change in the color of the nucleus of bronchiolus epithelium and T lymphocytes the airway bronchial asthma shown the occurrence of browning apoptosis. The result shown a significant increase of apoptosis of bronchiolus epithelium on positive control group to compare with negative control group. The apoptosis of bronchiolus epithelium on JH1 shown an increase compare with positive control group. For JH2 and JH3 groups shown a decrease the apoptosis of bronchial epithelium compare with positive control group. And the research indicate that the unsignificant aptosis decrease were happen on a group with positive control instead of the group with negative control. Meanwhile, on JH1 group, apoptosis decrease were happening more significantly than the positive control group does, the aptosis increases were happen on JH2 and JH3 group, but its not capable to exceeding the positive control group apoptosis amount The conclusions is the black seed (Nigella sativa L.) extract can decrease apoptosis of bronchiolus epthelium on asthma mouse model in the third dose as the best result and the doses of black seed extract that were giving to the experiment mice can not increasing the apoptosis T Lymphocyte, thus requiring further research to figure out the perfect doses to increasing against respiratory tract apoptosis T Lymphocyte. Keyword: asthma, black seed, the apoptosis of bronchiolus epithelium, apoptosis limfosit T.
The Influence of The Environment And Mother’s Behaviour Towards Toddlers’ Diarrhea in Banjarbaru, South Kalimantan Nopy Faisal; Endang Sriwahyuni; Aminudin Afandhi
Indonesian Journal of Environment and Sustainable Development Vol 7, No 2 (2016)
Publisher : Graduate Program

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1120.55 KB)

Abstract

Diarrhea is a disease that causes high fatality in toddlers all over the world. 1.5 million children die each year due to suffering from diarrhea. Diarrhea is still a major health problem in Banjarbaru, it is included in the top 10 diseaseas in every year. Bad water quality, bad sanitation facility and mother’s unhygienic behaviour are the major cause of diarrhea in toddlers. This research aims to analyze the influence of the environment quality and mother’s behaviour towards toddlers’ diarrhea in Banjarbaru. The research variable consists of the well quality, family latrines, wastewater disposal facility, bacteriological quality of the well water, mother’s clean and healthy living behaviours (PHBS or Perilaku Hidup Bersih dan Sehat) as well as the incidence of diarrhea in toddlers. It is conducted in Landasan Ulin Public Health Center and North Banjarbaru Public Health Center with total sample of 50 toddlers. The data analysis used is univariate, bivariate and multivariate. The results showed that the mother’s PHBS (p = 0.005; OR = 13,077) and the bacteriological quality of the well water (p = 0,041; OR = 6,966) became the most influential variables of this toddlers’ diarrhea. The activities that are required in order to control the diarrheal diseases in Banjarbaru are change the mothers’ behaviour in the prevention of toddlers’ diarrhea, improve the environment quality with Community Lead Total Sanitation Program (STBM or Sanitasi Total Berbasis Masyarakat), making a Local Regulation for wastewater management, an enhancement of officers for prevention and control of diarrhea and awarding donations for low-income citizens.Key words: diarrhea, mother’s behaviour, sanitation, water, 
THE POST-COLONIAL READING ON KIRAN DESAI’S THE INHERITANCE OF LOSS Endang Sriwahyuni
PARAFRASE : Jurnal Kajian Kebahasaan & Kesastraan Vol 12 No 01 (2012)
Publisher : Universitas 17 Agustus 1945 Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (426.422 KB) | DOI: 10.30996/parafrase.v12i01.201

Abstract

Abstrak. Tujuan penelitian ini adalah untuk mengetahui identitas post kolonial dalam karakter Sai dalam The In heritance of Loss karya Kiran Desai. Identitas post kolonial dalam novel, yaitu identitas  budaya yang mewakili sisa efek dominasi kolonial pada budaya masyarakat, meliputi beberapa isu: Eurosentrisme, unhomeliness, dan mimikri. Studi ini mengadopsi kualitatif, metode ekstrinsik, dan pendekatan post kolonial. Hasil penelitian menunjukkan bahwa novel ini mencerminkan Euro sentrisme, unhomeliness dan mimikri dalam karakter Sai, dalam pikiran dan perasaannya tentang agama Kristen sebagai nilai-nilai Barat (Eurosentrisme), berhentinya praktek Hindunya (unhomeliness) dan peniruannya pada nilai-nilai Barat dalam cara, aksen, dan gaya hidup. Penelitian ini juga mengungkapkan bahwa pengalaman post kolonial Sai adalah warisan nilai dari biara dan kakeknya. Kata kunci: postcolonial literature, postcolonial identity, Eurocentrism, unhomeliness, mimicry
Daya Tarik Pesantren Darul Ulya Dalam Perspektif Ilmu-Ilmu Sosial Aprilia Audia; Endang Sriwahyuni; Novita Dewi Lestari; Wellfarina Hamer
SOCIAL PEDAGOGY: Journal of Social Science Education Vol 1 No 1 (2020): Social Pedagogy: Journal of Social Science Education
Publisher : Fakultas Tarbiyah dan Ilmu Keguruan IAIN Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.95 KB) | DOI: 10.32332/social-pedagogy.v1i1.2159

Abstract

Pondok Pesantren Darul Ulya merupakan salah satu Pondok Pesantren Tradisional yang berada di Kota Metro. Letaknya yang berada di dekat kawasan Pendidikan Kota Metro membuat para siswa maupun mahasiswa yang berada dekat dengan Pondok ini tertarik untuk menimba ilmu agama di Pondok Pesantren Darul Ulya ini. Dalam penilitian ini penulis mengkaji beberapa faktor pendorong mahasiswa untuk masuk ke Pondok Pesantren Darul Ulya ini dari beberapa perspektif ilmu-ilmu sosial, yang diantaranya adalah ilmu sejarah, ilmu geografi, ilmu sosiologi, dan ilmu ekonomi. Kata Kunci: Pondok Pesantren, ilmu-ilmu sosial