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All Journal Jurnal Surya Medika KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat Sanitasi: Jurnal Kesehatan Lingkungan JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Jurnal Kesehatan Kusuma Husada Jurnal Farmasetis
Mastuti Widi Lestari
Sekolah Tinggi Ilmu Kesehatan Nasional
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Relationship between Body Mask Index (BMI) and Titer C-Reactive Protein in Women Hari Saktiningsih; Sulasmi; Mastuti Widi Lestari
KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat Vol 7 No 2 (2021): December
Publisher : Universitas Widya Gama Mahakam Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24903/kujkm.v7i2.1053

Abstract

Abstract Background: The prevalence of metabolic syndrome is certainly likely to increase with the increasing prevalence of obesity. A reliable indicator and easy-to-use for measuring body fat is body mass index (BMI), in the state of obesity there is a disruption of adiposity balance that is released and as an early marker of inflammation and triggers the formation of C-Reactive protein in the liver. Objectives: The goal of the study was to analyze the relationship between BMI and Titer C-Reactive Protein in women.. Research Metodes: This study is an observational analytical study with a cross sectional approach. The population in this study was women aged 25-65 years. A total of 39 samples were conducted in quota sampling. The data was analyzed with Kendal's tau non parametric test. Findings: The results of the study obtained a value of significance or Sig. (2-tailed) 0.908 > 0.05, This result states that there is no relationship between body mass index and titer C-Reactive protein. Correlation coefficient value is -0.015, express a very weak linear relationship. Negative values indicate the opposite direction of the relationship, where the higher the BMI, the lower the C-Reactive protein titer. Conclusion: Statistical test results obtained a value of p (0.908) > α (0.05), it states that no significant association between BMI and Titer C-Reactive Protein in women
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL LIMBAH KULIT PISANG KEPOK (Musa paradisiaca L.) TERHADAP Shigella dysenteriae Vector Stephen Dewangga; Mastuti Widi Lestari
Jurnal Kesehatan Kusuma Husada Vol. 12 No. 2, Juli 2021
Publisher : Universitas Kusuma Husada Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.181 KB) | DOI: 10.34035/jk.v12i2.713

Abstract

Kasus diare di Indonesia pada umumnya disebabkan oleh masalah kebersihan lingkungan, makanan, dan infeksi mikroorganisme. Salah satu mikroorganisme penyebab diare adalah bakteri Shigella dysenteriae. Kulit pisang diketahui mempunyai sifat anti bakteri. Tujuan penelitian ini untuk mengetahui kemampuan ekstrak etanol 96% limbah kulit pisang kepok (Musa paradisiaca L.) membentuk zona radikal terhadap Shigella dysentriae berdasarkan variasi konsentrasi. Penelitian ini menggunakan desain penelitian analitik eksperimental dengan pendekatan post test with control. Ekstrak etanol 96% kulit Musa paradisiaca L. dibuat dengan variasi konsentrasi 20%, 40%, 60%, 80%, dan 100%. Aktivitas antibakteri diuji dengan metode cakram dengan kontrol negatif DMSO 10% dan kontrol positif ciprofloxacin 5 µg, dan dilanjutkan dengan analisis Anova satu jalur. Hasil dari penelitian ini menunjukkan terbentuknya zona hambat pada konsentrasi 20%, 40%, 60%, 80%, dan 100% berturut-turut 6,09 mm, 6,26 mm, 6,58 mm, 7,58 mm, dan 9,00 mm. Hal ini menunjukkan semakin tinggi konsentrasi zat antibakteri maka semakin besar juga zona hambat radikal yang terbentuk. Uji Anova satu jalur diperoleh nilai p ≤ 0,05, sehingga dapat disimpulkan bahwa ekstrak etanol 96% kulit Musa paradisiaca L. mampu menghambat pertumbuhan Shigella dysenteriae. Diarrhea cases in Indonesia are generally due to environmental problems, food hygiene, and microorganism infections. One of the microorganisms that cause diarrhea is Shigella dysenteriae. Banana peels are known have antibacterial properties. The purpose of this project was to study the antibacterial activity of 96% ethanol extract of Kepok banana (Musa paradisiaca L.) peel waste with variations concentration on the growth of Shigella dysenteriae. This study uses an experimental analytic research design by post test with control. Ethanol extract 96% of the peels of Musa paradisiaca L. was made with a composition variation of 20%, 40%, 60%, 80%, and 100%. Antibacterial activity was tested by disc-method with DMSO as negative control and ciprofloxacin as positive control. The data obtained were analyzed with one way Anova. The results of this study indicate the formation of inhibition zones at concentrations of 20%, 40%, 60%, 80%, and 100% collected 6.09 mm, 6.26 mm, 6.58 mm, 7.58 mm, and 9,00 mm. This data shows that the greater the concentration of antibacterial substances, the greater the zone of radical inhibition formed. Anova one path test obtained p value 0.001, so it can conclude that ethanol extract 96% of the skin of Musa paradisiaca L. able to inhibit the growth of Shigella dysenteriae.
Hubungan Nilai MPV (Mean Platelet Volume) dengan Kadar Glukosa Darah pada Penderita Diabetes Melitus Tipe 2: The Correlation Of MPV (Mean Platelet Volume) Value with Blood Glucose Levels in Patients of Diabetes Mellitus Type 2 Hari Saktiningsih; Mastuti Widi Lestari; Warih Anjari Dyah Kusumaning Ayu
Jurnal Surya Medika (JSM) Vol. 8 No. 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3589

Abstract

Diabetes mellitus (DM) type 2 is a group of disorders characterized by elevated blood glucose levels (hyperglycemia). This condition is caused by a decrease in the body's ability to respond to insulin (insulin resistance) or due to a decrease in the amount of insulin by the pancreas. Mean platelet volume (MPV) indicates platelets' mean size and activity. In diabetics, a high MPV value can predict an increased risk of thrombosis and chronic complications. This study aimed to determine the relationship between MPV values and blood glucose in Type 2 DM. The type of this research was observational analytic with a cross-sectional design; the respondents were type II diabetes mellitus patients at the Gajahan Health Center Surakarta from May to July 2018. The results of the Spearman test obtained p = 0.082 so that p > (0.05), then H0 is accepted and H1 is rejected so that it can be concluded that there is no relationship between MPV values and Blood Glucose Levels in patients with type II diabetes mellitus.
Hubungan Kadar Timbal Dalam Darah dengan Kadar Hemoglobin pada Operator SPBU Gombel Semarang: The Correlation of Lead Level in the Blood with Hemoglobin Level on the Operator of Public Refueling Station in Gombel Semarang Susiani Susiani; Mastuti Widi Lestari
Jurnal Surya Medika (JSM) Vol. 8 No. 3 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i3.3606

Abstract

Lead is a heavy metal that is added in the manufacture of gasoline. Lead acts as an anti-knock to increase engine efficiency. Lead can cause air pollution. The main sources of lead pollution are motor vehicle fumes and gasoline fumes. Operator of Public Refueling Station are workers at high risk of being exposed to lead. The continuous accumulation of lead can inhibit the formation of hemoglobin. Research is needed to know the relationship between lead level in blood and hemoglobin level on the Operator of Public Refueling Station in Gombel Semarang. The research type is observational descriptive analytic with a cross sectional design. The research sample of 18 respondents is the entire population of Operator of Public Refueling Station in Gombel Semarang. Lead level in blood is an independent variable. Hemoglobin level is the dependent variable. Lead levels were measured by the ICP-MS method and using the Agilent 7700 X. Hemoglobin levels were measured by the SLS-Hemoglobin Method and using the Sysmex XN 1000. The research result was lead level in blood 1,6-5,7 μg/dL, hemoglobin level 12,4-18,1 g/dL. Test result of Spearman correlation obtained p= 0,581 ; r=-0,139. It was concluded that there was no significant correlation between the level of blood lead and level of hemoglobin on Operator of Public Refueling Station in Gombel Semarang.
Hubungan Kadar Kadmium (Cd) dalam Rambut dengan Kadar Asam Urat pada Pekerja Las di Kelurahan Banaran, Kecamatan Grogol, Kabupaten Sukoharjo Pradita Isdio Mahendra Renza; Mastuti Widi Lestari
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 8, No 1 (2023)
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/jumantik.v8i1.11715

Abstract

Welding workers are potentially exposed to cadmium containing fumes during the welding process. Cadmium is one of the heavy metals that is considered toxic. Cadmium heavy metals can interfere with the health of body organs such as the kidneys. Accumulation of cadmium in the kidneys can decrease the excretory activity of the veins. Resulting impact is an increase in uric acid levels in the body (hyperuricemia). This study aims to determine the relationship between cadmium levels in hair and uric acid levels of welding workers in Kelurahan Banaran, Kecamatan Grogol, Kabupaten Sukoharjo. Study was conducted using a purposive sampling method on 15 male welding workers. Cadmium levels in the hair were examined using FAAS. Uric acid levels in capillary blood are checked using POCT. Results of the examination of cadmium levels in 15 samples were still within the limits set by Biolab <0.10 ppm. Uric acid content examination results obtained 2 of the 15 samples had high uric acid levels >7.2 mg/dl. Data were analyzed using SPSS Pearson's Correlation Test. Results of the Pearson correlation test showed that there was no relationship between cadmium levels in the hair and uric acid levels in welding workers in Kelurahan Banaran, Kecamatan Grogol, Kabupaten Sukoharjo.Keywords: Uric Acid, Cadmium, Pearson Correlation, Welding Workers
Analisis paparan kadar kadmium (CD) pada rambut dengan kejadian hipertensi pekerja las di Kelurahan Banaran, Kecamatan Grogol, Kabupaten Sukoharjo Karina Winda Rofifah; Mastuti Widi Lestari
Sanitasi: Jurnal Kesehatan Lingkungan Vol. 16 No. 1 (2023): Februari 2023
Publisher : Poltekkes Kemenkes Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29238/sanitasi.v16i1.1399

Abstract

Kadmium merupakan logam berat yang paling banyak ditemukan di lingkungan. Cd yang masuk ke dalam tubuh secara terus-menerus dapat menyebabkan keracunan, seperti hipertensi. Pekerja bengkel las berpotensi terpapar logam Cd melalui fumes yang terhirup pada saat proses pengelasan. Selain melalui pernafasan, Cd juga dapat masuk melalui rambut. Pada tahun 2017 di Puskesmas Grogol ditemukan 3.896 kasus berdasarkan pengkajian penderita hipertensi tertinggi di Kabupaten Sukoharjo. Tujuan penelitian ini untuk mengetahui hubungan kadar kadmium (Cd) pada rambut dengan kejadian hipertensi pekerja las di Kelurahan Banaran, Kecamatan Grogol, Kabupaten Sukoharjo. Jenis penelitian ini adalah analitik observasional dengan menggunakan pendekatan Cross Sectional. Data yang dianalisis diuji dengan menggunakan aplikasi pengolahan data statistik SPSS versi 25.0. Analisis statistik menggunakan uji Mann Whitney nilai asymp.sig 0,552 maka p>0,05. Dari hasil penelitian tersebut disimpulkan bahwa tidak terdapat hubungan antara kadar kadmium (Cd) pada rambut dengan kejadian hipertensi pekerja las di Kelurahan Banaran, Kecamatan Grogol, Kabupaten Sukoharjo. Disarankan untuk menggunakan alat pelindung diri untuk menimalisasi paparan kadmium dan untuk pemilik bengkel las dapat mengkondisikan work station yang sirkulasi udaranya baik dengan ventilasi besar dan luas.
Perbedaan Kadar S-Phenilmercapturic Acid (sPMA) Urin pada Pegawai Lapangan dan Non Lapangan Perusahaan Bahan Bakar Minyak Warsini; Mastuti Widi Lestari
Jurnal Farmasetis Vol 12 No 4 (2023): Jurnal Farmasetis: November 2023
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/far.v12i4.1567

Abstract

Industri berbasis minyak bumi menghasilkan cemaran benzena di udara. Paparan benzena di udara meningkat dari emisi kendaraan bermotor. Biomarker paparan benzena dalam tubuh adalah kadar S-Phenylmercapturic acid. Tujuan dari penelitian ini adalah mengetahui perbedaan kadar S-Phenylmercapturic acid urin pada pegawai lapangan dan non lapangan di terminal bahan bakar di Kota Malang. Penelitian ini menggunakan desain studi cross sectional dengan jumlah sampel 22 pegawai. Sampel menggunakan urin sewaktu yang di tampung pada saat akhir giliran kerja diperiksakan kadar S-Phenylmercapturic acid urin di Laboratorium Prodia IndTox Cikarang. Kadar S-Phenylmercapturic acid pada pegawai lapangan yaitu antara 0,37-3,92 μg/g kreatinin, sedangkan pada pegawai non lapangan antara 0,17-4,81 μg/g kreatinin. Hasil uji perbedaan dengan menggunakan uji parametrik yaitu dengan uji T didapatkan nilai signifikansi untuk kadar S-Phenylmercapturic acid terhadap posisi pekerjaan sebesar 0,936 (p > 0,05). Hasil analisis menunjukkan tidak terdapat perbedaan antara pegawai lapangan dan non lapangan perusahaan Bahan Bakar Minyak di kota Malang.
Co-Authors Hari Saktiningsih Hari Saktiningsih Karina Winda Rofifah Pradita Isdio Mahendra Renza Sulasmi Susiani Susiani Vector Stephen Dewangga Warih Anjari Dyah Kusumaning Ayu Warsini