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ANALISIS EFEKTIFITAS CEFAZOLINE, CEFTRIAXONE, CEFOTAXIME SEBAGAI ANTIBIOTIK PROFILAKSIS PADA PASIEN SECTIO CAESAREA Ninik Mas Ulfa; Selly Septi Fandinata; Yuni Hendrawati
As-Syifaa Jurnal Farmasi Vol 11, No 2 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v11i2.567

Prophylactic antibiotics is very necessary in labor with the aim of avoiding infection during SC surgery. This study was descriptive observational with retrospective data collection. The subjects observed in this study were medical records documents of SC patients in RJI hospitals in the area of South Surabaya for the period February - April 2017, with 39 documents were divided into 3 groups. Group A which received Cefazolin, Group B received Ceftriaxone, and Group C which received Ceftaxime. This study was comparison of the effectiveness of these 3 prophylactic antibiotics was measured by temperature parameters, leukocytes and observation of the condition of the surgical wound. Based on statistical analysis using the Kruskal Wallis test, it was found that the effectiveness of antibiotic prophylaxis Cefazolin was more effective in reducing the temperature and leukocytes of SC patients compared to Ceftriaxon and Cefotaxim, with an average rating of Cefazolin in temperature parameters of 27.58 and an average ranking in leukocyte parameters ie 25.81. Meanwhile in observing surgical wounds from three groups of antibiotic prophylaxis there was no redness, no swollen wounds, no discharge and no pus from surgical wounds

The Level Of Knowledge on the Use Of NSAIDs As Analgesic For Dysmenorrhea Case In Faculty of Health Universitas Muhammadiyah Lamongan Primanitha Ria Utami; Devi Ristian Octavia; Selly Septi Fandinata
Jurnal MIDPRO Vol 12, No 2 (2020): JURNAL MIDPRO
Publisher : Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/md.v12i2.245

Non-steroidal anti-inflammatory (anti-inflammatory) drugs, or better known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) or NSAIDs are a group that has analgesic (pain reliever), anti-pyretic (fever) properties. to determine the level of knowledge on the use of NSAIDs as anti-pain in cases of dysmenorrhea in the University of Muhammadiyah Lamongan. The research design used in this research is descriptive, in taking the sample using the total sampling technique. Collecting data by distributing questionnaires with data analysis presented in tabular form. The results of this study indicate that of the 266 respondents, almost all respondents know about knowledge of dysmenorrhea well (83.8%). In the results of this study, there were still respondents who did not know the proper use of NSAIDs as analgesic. So in this case the role of pharmaceutical personnel is needed in providing information or education to people who consume NSAIDs, in order to achieve a quality of life for the community and avoid unwanted therapeutic responses. Keywords : NSAID ; dysmenorrhea ; analgesic

Hubungan Antara Peran Pengawas Menelan Obat (PMO) dengan Keberhasilan Pengobatan Tuberkulosis Paru Kategori I Selly Septi Fandinata; Rizky Darmawan
Journal Syifa Sciences and Clinical Research Vol 1, No 2 (2019): Volume 1 Edisi 2 2019
Publisher : State University of Gorontalo

TB is an infectious disease caused by Gercobacterium tuberculosis that attacks the lungs and can cause disturbances in the respiratory tract. The DOTS Program can help the achievement of successful treatment targets. The role and motivation of PMO and family are essential for the successful treatment of lung TB patients. This type of study is an analytical observational research with prospective data collection in March – May 2019, which is recorded as medical data of patients diagnosed with lung TB category I in September – November 2018 at Rubaru Puskesmas Sumenep Regency. The purpose of this research is to know the role of PMO relationship with the successful treatment of lung TB category I. With the number of samples of this research 40 patients. The results of this study using Pearson correlation statistics indicate that the value significance 0.013 < 0.05, this means a significant link between the PMO role with the success of patient treatment. The value of the correlation coefficient R obtained from 0388, the relationship between PMO role and the success of patient treatment in direct, this means that the greater the role of PMO then the higher the success of treatment, the smaller the PMO role then the lower the Successful treatment. In addition, the table also gained that the relationship between the PMO role and the successful treatment of the patient is weak due to the correlation coefficient of R < 0.4.

Profil Penggunaan Obat Antihipertensi di Puskesmas Surabaya. Iin Ernawati; Selly Septi Fandinata; Silfiana Nisa Permatasari
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 3, No 2 (2022): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v3i2.7679

ABSTRAKHipertensi adalah penyakit kronis dengan tekanan darah sistolik dan diastolic meningkat ≥140/90 mmHg. Prevalensi pasien hipertensi meningkat di Puskesmas, sehingga perlu adanya observasi penggunaan obat antihipertensi sebagai data awal untuk melakukan monitoring penggunaan dan pengadaan obat. Penelitian ini dilakukan untuk mengetahui profil penggunaan obat antihipertensi yang meliputi nama obat, golongan dan aturan pakai obat antihipertensi. Penelitian ini merupakan penelitian observasional cross-sectional, yang dilakukan di 5 Puskesmas di Surabaya antara lain Puskesmas Benowo, Jeruk, Tambak Rejo, Gayungan, dan Ketabang. Pengumpulan data retrospektif dilakukan selama 2 bulan pada bulan Mei-Juni 2020. Berdasarkan hasil penelitian diketahui bahwa mayoritas pasien mendapatkan obat antihipertensi golongan CCB (Calcium Channel Blocker ) sebesar 82,37% dengan obat amlodipine 5 mg (49,19%) dan amlodipine 10 mg (32,95%), sedangkan untuk penggunaan obat antihipertensi kombinasi, mayoritas golongan CCB dan Diuretik Thiazid dengan nama obat Amlodipine 5 mg dan Hidroklorotiazid 25 mg (6,63%). Obat Amlodipine sebagai obat antihipertensi golongan CCB yang paling banyak digunakan dengan aturan pakai sekali sehari. Amlodipine salah satu obat antihipertensi yang toleran terhadap pasien geriatri dengan efek samping vasodilatasi yang lebih rendah dibanding obat lain dari golongan CCB dan memiliki waktu paruh yang panjang sehingga dapat diaplikasikan pada pasien kronis rawat jalan hipertensi dengan pemberian sekali sehari. Kata kunci : Obat antihipertensi; Puskesmas; Hipertensi; Profil. ABSTRACTHypertension is a chronic disease that is an increase in systolic and diastolic blood pressure 140/90 mmHg. The prevalence of hypertension patients is increasing at the Puskesmas, so it is necessary to observe the usage profile of antihypertensive drugs. This research is needed as initial data to monitor the use and procurement of drugs. This study aims to determine the profile of the use of antihypertensive drugs which includes the name of the drug and the rules of antihypertensive drugs. This observation is a cross-sectional study, which was conducted in 5 Public Health Center (Puskesmas) in Surabaya, including Benowo, Jeruk, Tambak Rejo, Gayungan, and Ketabang Public Health Center. Retrospective data collection was carried out for two months in May-June 2020. Based on the results of the study, it was found that the majority of patients received antihypertensive drugs from the Calcium Channel Blocker (CCB) class of 82.37% with amlodipine 5 mg (49.19%) and amlodipine 10 mg (32.95%), while for the use of combination antihypertensive drugs, the majority CCB and Thiazide Diuretics with the drug names Amlodipine 5 mg and Hydrochlorothiazide 25 mg (6.63%). Amlodipine as an antihypertensive drug of the CCB class is the most widely used in this research. Amlodipine is an antihypertensive drug that is tolerant to geriatric patients with lower vasodilation side effects than other drugs from the CCB group and has a long half-life so it can be applied to chronic hypertension outpatients and is given once a day. Keywords : Antihypertensive drug; Community Health Center; Hypertension; Profile.

The Effect of The Number of Drugs Received On The Level of Adherence to Drug Consumption (Morisky, Green, Levine Adherence Scale Questionnaire) of Hypertensive Patients Iin Ernawati; Selly Septi Fandinata; Silfiana Nisa Permatasari
STRADA Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Institut Ilmu Kesehatan STRADA Indonesia

Hypertension is a chronic disease that requires long-term treatment, where it is very prone to non-adherence in taking antihypertensive drugs. This study aims to determine the effect of the number of drugs received by patients on the level of adherence to the consumption of antihypertensive drugs. This research is a cross-sectional observational study that was conducted in 4 community health centers in Surabaya City. The measurement of adherence in this study used the Indonesian version of the MGLS questionnaire. The number of subjects in this study was 143 which fit the inclusion criteria. The majority of the adherence levels of the study subjects were moderate (MGLS questionnaire). Based on statistical analysis, it is known that there is a significant effect (P = 0.035) of the number of drugs received by patients on the level of drug consumption adherence e as measured using the Indonesian version of the MGLS questionnaire.

The Effects of Self Reminder Card to the Successful Treatment of Blood Pressure of Hypertension Patients in Community Health Centers in Surabaya Selly Septi Fandinata; Iin Ernawati
STRADA Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Institut Ilmu Kesehatan STRADA Indonesia

Hypertension treatment aims to control blood pressure. Self-reminder card is a tool that can help patients to avoid forget in taking the medicine. The purpose of determine the effects of self-reminder cards on the successful treatment of blood pressure in hypertension patients at community health centers in Surabaya. Research design Quasi Experimental control and self-reminder card group pre post prospective with Wilcoxon and Mann Whitney test Analysis. The sample was 115 patients. The results showed that the systolic blood pressure of the patients pre post the intervention group (p = 0.009) and test of both groups (p = 0.009) so that effect the successful in reducing systolic blood pressure of hypertension patients. In the pre post diastolic blood pressure of the intervention group (p = 0.016) and test was conducted for both groups (p = 0.935) so that no effect the successful in reducing diastolic blood pressure in hypertension patients.

Peningkatan Pengetahuan Dan Self Care Kepatuhan Kader Dan Masyarakat Pada Pasien Diabetes Melitus Di Era Digital Eziah Ika Lubada; Selly Septi Fandinata; Rizky Darmawan
Indonesian Journal of Community Dedication in Health (IJCDH) Vol 3 No 01 (2022): IJCDH Vol 03 No 01
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/ijcdh.v3i01.4645

Abstrak Diabetes melitus (DM) adalah penyakit metabolik dengan karakteristik hiperglikemia yang terjadi akibat adanya kelainan sekresi insulin, kerja insulin, atau keduanya. DM saat ini benyak dialami bukan hanya di usia Lansia tetapi mulai banyak dialami di usia Dewasa. WHO memperkirakan pada tahun 2014 sekitar 422 juta orang dewasa berusia di atas 18 tahun hidup dengan DM. Keberhasilan proses kontrol penyakit DM sangatlah ditentukan oleh kepatuhan penggunaan obat agar tidak menimbulkan komplikasi. Pasien DM memerlukan terapi jangka panjang, maka kepatuhan penggunaan obat merupakan salah satu faktor keberhasilan terapi. Perkembangan teknologi dalam bidang Kesehatan mengarah pada mobile health (e-health) dengan menggunakan smartphone sebagai pengingat untuk mengkonsumsi obat. Kegiatan pengabdian masyarakat ini dilakukan pada warga RW 7 Dukuh Kupang Surabaya. Kegiatan antara lain antara lain cek kesehatan, ceramah tentang pentingnya kepatuhan minum obat DM serta cara mengunduh dan menggunakan aplikasi minum obat pada smart phone masing-masing. Untuk mengetahui keberhasilan kegiatan maka seluruh peserta akan diberikan kuisioner pre saat registrasi dan kuisioner post sebelum acara berakhir tentang materi kegiatan. kegiatan dihadiri oleh 30 peserta dengan jumlah peserta perempuan sebanyak 26 Peserta (86,67%) dan 11 peserta laki-laki (13,33%). Rentang usia terbanyak adalah 46-55 dan 56-65masing - masing sebanyak 11 pasien (36,67%). Terdapat peningkatan tingkat pengetahuan peserta dari hasil kuisioner pre 14 peserta (46,67%) berpengetahuan baik menjadi 19 peserta (63,33%) pada kuisioner post. . Kata kunci— Diabetes Mellitus, Kepatuhan, Kuisioner

Comparison of the Effect of Morning Versus Night Amlodipine Administration on Blood Pressure Reduction in Primary Hypertensive Patients: Perbandingan Pengaruh Waktu Pemberian Amlodipin Pagi Versus Malam Terhadap Penurunan Tekanan Darah Pasien Hipertensi Primer Eziah Ika Lubada; Selly Septi Fandinata; Rizky Darmawan
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 2 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i2.304

Human blood pressure goes according to a circadian rhythm, blood pressure drops during sleep and increases in the morning this happens in most individuals. One of the hypertension drug therapies is Amlodipine Calcium Channel Blocker class which has a long half-life, so it can be used once a day, and amlodipine works as a long-acting antihypertensive. On reducing blood pressure in primary hypertensive patients. The design of this study was a cohort by measuring blood pressure before and after administration of amlodipine therapy in the morning or amlodipine at night in outpatients with a diagnosis of primary hypertension who received amlodipine therapy at the “X” Clinic in Surabaya with retrospective data collection. The results of this study were obtained from 20 patients who stated that there was no significant difference in difference in systolic and diastolic blood pressure between January and December 2019 in patients receiving amlodipine therapy 5 mg in the morning, 10 mg in the morning, 5 mg in the evening and 10 mg in the evening. There is an effect of giving amlodipine therapy in the morning and evening.

Penyuluhan Penggunaan Tanaman Obat Keluarga (TOGA) Daun Binahong Sebagai Anti-Bakteri Djamilah Arifiyana; Selly Septi Fandinata; Andhika Dwi Aristyawan
JPKMI (Jurnal Pengabdian Kepada Masyarakat Indonesia) Vol 4, No 4: November (2023) in Press
Publisher : ICSE (Institute of Computer Science and Engineering)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36596/jpkmi.v4i4.722

Abstrak: Gaya hidup back to nature, atau kembali ke alam saat ini semakin banyak diminati seiring dengan kesadaran masyarakat akan bahaya yang ditimbulkan dari penggunaan bahan kimia. Hal ini membuat penggunaan Tanaman Obat Keluarga (TOGA) kembali populer dikalangan masyarakat di Indonesia. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan tentang pemanfaatan dan pengolahan TOGA daun Binahong sebagai bahan alami untuk membuat sediaan yang bermanfaat bagi tubuh sebagai upaya preventif dan promotif pada musim pancaroba. Metode pelaksanaan kegiatan ini adalah melalui penyuluhan yang meliputi metode ceramah, diskusi, dan praktik langsung. Masyarakat sasaran kegiatan ini adalah warga RT 13 RW 01 Kelurahan Jagir Surabaya. Kegiatan terdiri dari beberapa tahapan, yakni Pra survey dan perizinan lokasi kegiatan, Penyuluhan tentang penyakit yang muncul saat pancaroba sekaligus penyerahan TOGA, Pemantauan pertumbuhan TOGA, Penyuluhan budidaya sederhana TOGA dan pembuatan sediaan dauh binahong, serta Evaluasi kebermanfaatan pelaksanaan kegiatan pemanfaatan daun binahong sebagai anti-bakteri. Setelah serangkaian kegiatan terlaksana, diperoleh hasil kuesioner menunjukkan bahwa 100% dari warga RT 13 RW 01 Kelurahan Jagir Surabaya setuju bahwa kegiatan ini bermanfaat dan dapat diikuti dengan jelas dan baik, 97,06% setuju bahwa kegiatan ini dapat diterapkan dalam kehidupan sehari-hari, serta 100% warga setuju untuk mengaplikasikan pembuatan pestisida alami di rumah dan menyatakan bahwa bahan yang dibutuhkan dalam pembuatannya mudah didapatkan.Abstract: ‘Back to nature’ lifestyle is currently increasing in demand along with public awareness of the dangers posed by the use of chemicals. This has made the use of Tanaman Obat Keluarga (TOGA) popular again among people in Indonesia. This community service activity aims to increase knowledge about the use and processing of TOGA Binahong leaves as a natural ingredient for making preparations that are beneficial for the body as a preventive and promotive effort during the transition season, as well as providing education about TOGA cultivation in a simple way. The method for implementing this activity is through counseling which includes lecture, discussion and direct practice methods. The target community for this activity are residents of RT 13 RW 01, Jagir, Surabaya. The activity consists of several stages, namely Pre-survey and licensing of activity locations, Counseling about diseases that appear during the transition as well as handing over TOGA, Monitoring the growth of TOGA, Counseling on simple cultivation of TOGA and making binahong leaf preparations, as well as Evaluation of the usefulness of implementing activities to use binahong leaves as an anti-bacteria. After a series of activities were carried out, the results of the questionnaire showed that 100% of the residents of RT 13 RW 01, Jagir Subdistrict, Surabaya agreed that this activity was useful and could be followed clearly and well, 97.06% agreed that this activity could be applied in their daily life, and 100% of residents agreed to apply natural pesticide production at home and stated that the materials needed to make it were easy to obtain.

Changes in Mean Arterial and Blood Pressure in Using Nicardipine in Hypertensive Crisis Patients at the Hajj General Hospital Surabaya from August to December 2021 Selly Septi Fandinata; Rizky Darmawan; Ninik Mas Ulfa; Deddy Aryanda Putra
Borneo Journal of Pharmacy Vol. 6 No. 1 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i1.3493

Hypertension crisis is one of the most common disease problems; it will cause complications and death. Therapeutic management guidelines that the calcium channel blocker group, one of which is nicardipine, can increase the achievement of goals in mean arterial pressure (MAP) in preventing the progression of organ damage. This study aimed to evaluate the use of nicardipine therapy on the MAP and blood pressure (BP) in patients with hypertension crisis. The research design was cross-sectional with statistical analysis—retrospective data collection at Hajj General Hospital Surabaya for August to December 2021. The number of samples in this study matched the inclusion criteria; 20 patients were obtained, 16 with a diagnosis of hypertension emergency, and four with hypertension urgency who received single or combined intravenous nicardipine therapy <0.005 with an average BP decrease of pre 20.375±31.492/103.50±10.400 mmHg and post 121.34±14.364/81.80±11.186 so that intravenous nicardipine therapy was significant in reducing systolic and diastolic BP. In the profile of the MAP value statistically using the paired T-test, it was found that the P-value was 0.000 < 0.005 with a decrease in the MAP pre-value of 135.028±13.8857 mmHg and post 93.650±8.9499 mmHg, showing a reduction in MAP as expected. In conclusion, using nicardipine intravenously at a 5 mg/hour dose has shown an optimal decrease in BP and MAP in hypertensive emergency and urgency patients.

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