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Antioxidan Activity from Methanol Extract of Kratom Leaves (Mitragyna speciosa) Maseration Result Using The DPPH Method: Aktivitas Antioksidan Ekstrak Metanol Daun Kratom (Mitragyna speciosa) Hasil Maserasi Menggunakan Metode DPPH Andhika Dwi Aristyawan; Anggi Ayu Windari; Mercyska Suryandari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 2 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i2.357

Abstract

Antioxidants are compounds that can prevent the formation of free radicals. Kratom is a typical plant from South Putussibau area, in West Kalimantan. The kratom plant contains alkaloids, triterpenoid-steroids, saponins, tannins and flavonoids. The main component of kratom leaves is an indole alkaloid that is efficacious as an antioxidant. The goal is to determine the antioxidant activity of kratom leaf extract (Mitragyna speciosa). The method used is the measurement of the reduced amount of DPPH from an antioxidant compound UV-Vis spectrophotometrically at a wavelength of 517nm using Vitamin C as a comparison. The extraction method used is maceration. The test was sampled 10 mg of kratom leaf extract (Mitragyna speciosa) with 10 ppm, 20 ppm, 30 ppm, 40 ppm, and 50ppm concentrations, then repeated 3 times. The results of the antioxidant activity of kratom leaves (Mitragyna speciosa) were expressed with IC50 values of 44,169 ± 0.5313 with an RSD value of 1.202%. Then it can be concluded that kratom leaf methanol extract (Mitragyna speciosa) has a very strong antioxidant activity with an IC50 value of 44,169 ± 0.5313 with an RSD value of 1.202%.
Penyuluhan Penggunaan Tanaman Obat Keluarga (TOGA) Daun Binahong Sebagai Anti-Bakteri Djamilah Arifiyana; Selly Septi Fandinata; Andhika Dwi Aristyawan
JPKMI (Jurnal Pengabdian Kepada Masyarakat Indonesia) Vol 4, No 4: November (2023) in Press
Publisher : ICSE (Institute of Computer Science and Engineering)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36596/jpkmi.v4i4.722

Abstract

Abstrak: Gaya hidup back to nature, atau kembali ke alam saat ini semakin banyak diminati seiring dengan kesadaran masyarakat akan bahaya yang ditimbulkan dari penggunaan bahan kimia. Hal ini membuat penggunaan Tanaman Obat Keluarga (TOGA) kembali populer dikalangan masyarakat di Indonesia. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan tentang pemanfaatan dan pengolahan TOGA daun Binahong sebagai bahan alami untuk membuat sediaan yang bermanfaat bagi tubuh sebagai upaya preventif dan promotif pada musim pancaroba. Metode pelaksanaan kegiatan ini adalah melalui penyuluhan yang meliputi metode ceramah, diskusi, dan praktik langsung. Masyarakat sasaran kegiatan ini adalah warga RT 13 RW 01 Kelurahan Jagir Surabaya. Kegiatan terdiri dari beberapa tahapan, yakni Pra survey dan perizinan lokasi kegiatan, Penyuluhan tentang penyakit yang muncul saat pancaroba sekaligus penyerahan TOGA, Pemantauan pertumbuhan TOGA, Penyuluhan budidaya sederhana TOGA dan pembuatan sediaan dauh binahong, serta Evaluasi kebermanfaatan pelaksanaan kegiatan pemanfaatan daun binahong sebagai anti-bakteri. Setelah serangkaian kegiatan terlaksana, diperoleh hasil kuesioner menunjukkan bahwa 100% dari warga RT 13 RW 01 Kelurahan Jagir Surabaya setuju bahwa kegiatan ini bermanfaat dan dapat diikuti dengan jelas dan baik, 97,06% setuju bahwa kegiatan ini dapat diterapkan dalam kehidupan sehari-hari, serta 100% warga setuju untuk mengaplikasikan pembuatan pestisida alami di rumah dan menyatakan bahwa bahan yang dibutuhkan dalam pembuatannya mudah didapatkan.Abstract: ‘Back to nature’ lifestyle is currently increasing in demand along with public awareness of the dangers posed by the use of chemicals. This has made the use of Tanaman Obat Keluarga (TOGA) popular again among people in Indonesia. This community service activity aims to increase knowledge about the use and processing of TOGA Binahong leaves as a natural ingredient for making preparations that are beneficial for the body as a preventive and promotive effort during the transition season, as well as providing education about TOGA cultivation in a simple way. The method for implementing this activity is through counseling which includes lecture, discussion and direct practice methods. The target community for this activity are residents of RT 13 RW 01, Jagir, Surabaya. The activity consists of several stages, namely Pre-survey and licensing of activity locations, Counseling about diseases that appear during the transition as well as handing over TOGA, Monitoring the growth of TOGA, Counseling on simple cultivation of TOGA and making binahong leaf preparations, as well as Evaluation of the usefulness of implementing activities to use binahong leaves as an anti-bacteria. After a series of activities were carried out, the results of the questionnaire showed that 100% of the residents of RT 13 RW 01, Jagir Subdistrict, Surabaya agreed that this activity was useful and could be followed clearly and well, 97.06% agreed that this activity could be applied in their daily life, and 100% of residents agreed to apply natural pesticide production at home and stated that the materials needed to make it were easy to obtain.