Article Per Year (5 Year)
p-Index From 2019 - 2024
0.23
P-Index
This Author published in this journals
All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jaringan Laboratorium Medis
Sutji Kuswarini
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Analisis Risiko Kadar Enzim SGOT dan SGPT pada Penderita Diabetes Mellitus Tipe 2 Mochamad Rizal Maulana; Sutji Kuswarini
Jaringan Laboratorium Medis Vol 4, No 1 (2022): May 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i1.8489

Abstract

Diabetes mellitus is a group of metabolic diseases that occur due to abnormalities in insulin secretion and/or insulin action. In type 2 diabetes mellitus there is a decrease in glucose absorption by the body due to insulin resistance. Energy metabolism from glucose is processed through the synthesis of fatty acids in the liver (cytosol). The process that occurs continuously causes the accumulation of lipids in the liver or "fatty liver" so it is necessary to check the levels of transaminase enzymes which include SGOT and SGPT. The purpose of this study was to analyze the levels of SGOT and SGPT enzymes in patients with type 2 diabetes mellitus using the analytical observational method. The results of the examination of SGOT and SGPT levels from 30 patients who were taken randomly at Dr. Soetomo Surabaya will be analyzed with bar graphs and diagrams. Of 30 random samples, 20 samples (66.67%) had SGOT levels above the normal value, and 12 samples (40%) had SGPT with results above normal values. This study concludes that there is an increase in the levels of SGOT and SGPT enzymes in patients with type 2 diabetes mellitus.
SARI ETANOL, ETIL ASETAT ALANG-ALANG (IMPERATA CYLINDRICA) TERHADAP SUPEROXIDE DISMUTASE (SOD) St Khaerunnisa; Sutji Kuswarini; Suhartati Suhartati; Lina Lukitasari; Ira Humairah; Reza Arta BN; Gwenny IP
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 20, No 2 (2014)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v20i2.1080

Abstract

Oxidative stress has been considered as a mechanism involved in the pathogenesis and progression of many diseases such as:hypercholesterolemia and atherosclerosis. The objective of this current study was to know the potential antioxidant role of ethanol andethyl acetate extract of reeds (Imperata cylindrica) by investigation in rats fed with a high-cholesterol diet. Imperata cylindrica is richin antioxidants and has a cholesterol-reducing effect. A group of twenty four male albino Wistar rats was divided into four subgroups: anormal diet group (K0), a high-cholesterol diet group (K1), the same diet with ethanol extract of Imperata cylindrica group (K2), and thesimilar diet with ethyl acetate fraction of Imperata cylindrica group (K3),. After the treatment period, the hepatic antioxidant enzymeactivity (Superoxide dismutase/SOD) was determined. The rats fed on high-cholesterol diet with supplementation exhibited a significantelevation in SOD activity (p<0. 05), 61.6±12.4% inhibition, compared to normal animals 37.44±12.2%. The treated animals withethanol and ethyl acetate extract of Imperata cylindrica showed a significantly reduced the level of SOD activity (p<0.05, 29.90±5.6%as well as a 33.49±7.4% inhibition). The level of SOD activity when restored was closer to that in normal animals, signifying reversalof the oxidative stress. The study results showed that the treatment with Imperata cylindrica positively changed the hepatic antioxidantenzyme activities in high fat-diet rats, and thus had potential hypocholesterolemic and antioxidant effects. Imperata cylindrica couldprotect against oxidative stress linked to atherosclerosis and also decrease the atherogenic index.
Co-Authors Gwenny IP Ira Humairah Lina Lukitasari, M.Si Mochamad Rizal Maulana Reza Arta BN St Khaerunnisa Suhartati Suhartati