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All Journal Jurnal Tumbuhan Obat Indonesia Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Prosiding Seminar Nasional Sains Dan Teknologi Fakultas Teknik Indonesian Journal of Cancer Chemoprevention Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Pharmascience Indonesian Journal of Chemical Science Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmiah Cendekia Eksakta Media Farmasi Indonesia
Devi Nisa Hidayati
Universitas Wahid Hasyim
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences Other

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AKTIVITAS ANTIDIARE EKSTRAK ETANOL DAUN NANGKA (Artocarpus heterophyllus Lam.) DAN DAUN ANGSANA (Pterocarpus indicus Wild.) PADA MENCIT JANTAN GALUR BALB/C Yance Anas; Devi Nisa Hidayati; Aristya Kurniasih; Lalu Ksatria D.S.
Jurnal Ilmu Farmasi dan Farmasi Klinik JURNAL ILMU FARMASI & FARMASI KLINIK VOL. 13 NO. 1 JUNI 2016
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (492.92 KB) | DOI: 10.31942/jiffk.v13i1.1445

Abstract

ABSTRACT Traditionally, jackfruit leaves  (Artocarpus heterophyllus Lam.) and angsana leaves  (Pterocarpus indicus Wild.) have been used as an herb for diarrhea treatment. The purpose of this experimental study was to investigate the antidiarrheal effect of jackfruit leaves ethanol extract (JLEE) and angsana leaves ethanol extract (ALEE) on Balb/C male mice with castor oil-induced diarrhea method. The study design is a randomized matched two group post test-only. JLEE and ALEE produced by maceration. An antidiarrheal activity of both of extracts compared with loperamide-HCl 10 mg/Kg BW. JLEE (100, 200 and 400) mg/Kg BW and ALEE (80, 160 and 320) mg/Kg BW significantly (p <0.05) decrease the amount of liquid and soft feces, and delay the onset of diarrhea compared with controls (NaCl 0.9% 10 mL/Kg BW). The ability JLEE 400 mg/Kg BW and EEDA 320 mg/Kg BW on inhibiting the  formation liquid and soft feces are higher than loperamide HCl 10 mg/Kg BW with antidiarrheal effect amounted to 72.31%, 65.47%, and 54.46% respectively. The potency of JLEE and ALEE as antidiarrheal (ED50) are (20.85 and 3.52) mg/Kg BW respectively. However, in this study, a single dose of loperamide-HCl, JLEE and ALEE treatments are not able to heal the diarrhea symptom (p> 0.05). Keywords: Antidiarrheal, castor oil-induced diarrhea,ethanol extract, Artocarpus heterophyllus Lam., Pterocarpus indicus Wild.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN DAN KULIT BATANG BERENUK TERHADAP Bacillus cereus Devi Nisa Hidayati; Cicih Sumiarsih; Umroh Mahmudah; Anita Dwi Puspitasari
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & Farmasi Klinik Vol 15 No 2 Desember 2018
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (207.646 KB) | DOI: 10.31942/jiffk.v15i2.2563

Abstract

ABSTRACTThe plants (Crecentia cujete Linn) Are known to have antibacterial activity and can be used as a diarrhea drug due to microorganisms. Bacillus cereus is one of the bacteria that causes diarrhea.This aims to the study was antibacterial activity of ethanol extract of leaves (EL) and bark broodstock (EB) on Bacillus cereus. EL and EB were extracted with ethanol 96% using maceration method. Antibacterial activity test was carried out with disk diffusion method in EL with a concentration of 30%, 60%, 90%, 120% and 150%, and in EB using concentrations of 60%, 70%, 80%, 90% and 100% then antibacterial activity measurements were taken. by looking at the Diameter of the Inhibitory Area (DDH). The results of the EL and EB of antibacterial activity proved that EL and EB berenuk have antibacterial activity against Bacillus cereus.Keywords: Antibacterial, Crescentia cujete Linn, Bacillus cereus.
TOKSISITAS AKUT INFUSA KULIT ARI KACANG TANAH (Arachis hypogea L.) PADA MENCIT BALB/ C Risha Fillah Fithria; Ririn Lispita Wulandari; Devi Nisa Hidayati; Lilis Rejeki
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & Farmasi Klinik Vol 15 No 2 Desember 2018
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.109 KB) | DOI: 10.31942/jiffk.v15i2.2568

Abstract

ABSTRACTPeanut shell (PS) infusion has been shown to be antithrombocytopenia, but there has been no research on safety standards. This study aims to identify the symptoms of toxic effects, the potency of toxicity and histopathology of liver male Balb/C mice after a single dose of PS infusion. This research uses randomized matched posttest only control group design. Twenty five mice were divided into 5 orally dosage groups, ie, PS infusion with a dose of 0,026; 0.052; 0.104; 0.208 g/20gBW; and negative control of CMC Na 0.5%. The observation period is for 14 days. The results showed that single dose of PS infusion had a pseudo LD50 value ie > 0.208g/20gBW which was practically non toxic. Symptoms to watch out for the BW infusion were passive behavior, bradycnea, hair color change, hair loss, and weight loss at doses of 3 and 4. It is unclear whether liver damage ie inflammation, necrosis, and albuminous degeneration caused by PS infusion or other causes.keywords: acute toxicity, infusion, peanut shell
Antibacterial activity of ethanol extracts of hibiscus tiliaceus l. leaves from different extraction methods against Escherichia coli and Staphylococcus aureus Devi Nisa Hidayati; Hanik Rohmatul Maghfiroh; Aysah Safitri
Pharmaciana Vol 13, No 1 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (584.316 KB) | DOI: 10.12928/pharmaciana.v13i1.24671

Abstract

The leaves of sea hibiscus (Hibiscus tiliaceus L.) are known to have good antibacterial activity against Escherichia coli and Staphylococcus aureus, which is associated with the saponin, flavonoid, polyphenol, and tannin contents. Chemical compounds in plant extracts are, however, influenced by the extraction method used. This study aimed to determine the antibacterial activity of the ethanol extracts of Hibiscus tiliaceus L. leaves obtained using four different extraction methods against E. coli and S. aureus. In the maceration, percolation, reflux, or Soxhlet method, 200 g of the crude drug (i.e., dried sea hibiscus leaf powder) was extracted with 96% ethanol, and the derived extract was tested at 1%, 2%, 3%, 4%, and 5% concentrations. The disk diffusion method was used to test the antibacterial activity by observing and statistically analyzing the diameter of the zones of inhibition. Results showed that all the ethanol extracts have antibacterial properties against E. coli and S. aureus,with the maceration-produced extract forming significantly different zones of inhibition from the other methods (percolation, reflux, and the Soxhlet) at all concentrations.
Antibacterial Activities Of Papaya Seed (Carica papaya L.) Ethanol Extract With MAE And UAE Extraction Methods Towards Staphylococcus aureus Fini Hartanti; Devi Nisa Hidayati
Media Farmasi: Jurnal Ilmu Farmasi Vol 20, No 2: September 2023
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v20i2.24704

Abstract

Ethanol extract of papaya seeds produced by the maceration method has been shown to have antibacterial activity against S. aureus, P. aeruginous, S. thypi, and E. coli. This study aims to compare the antibacterial activity of the ethanol extract of papaya seeds obtained using the Microwave Assisted Extraction (MAE) and Ultrasound-Assisted Extraction (UAE) extraction methods on the growth of Staphylococcus aureus bacteria.Papaya seed powder was extracted using MAE and UAE extraction methods using 70% ethanol as a solvent in concentrations of 20%, 40%, 60%, and 80%. DMSO was used as negative control and chloramphenicol 30 g/disk as a positive control. The antibacterial activity test method used the disk diffusion method. The parameter observed was DDH (Diameter of Inhibitory Area) which was statistically analyzed using Two Way Anova at a 95% confidence level.The results showed that the ethanol extract of papaya seeds produced from the MAE and UAE extraction methods had antibacterial activity against Staphylococcus aureus in all concentration series. The statistical test showed a significant difference (p<0.05) in antibacterial activity against Staphylococcus aureus extracts obtained from two extraction methods: MAE and UAE. UAE method is recommended use. 
Penyuluhan dan Praktik Pengelolaan Pascapanen Tanaman Obat di Plalangan Gunungpati Semarang: The Socialization and Practice of Post-harvest Management for Medicinal Plants at Plalangan Gunungpati Semarang Dewi Andini Kunti Mulangsri; Devi Nisa Hidayati; Anita Dwi Puspitasari; Mutia Rahmatun; Salsabilla Putri Buana Pasha; Shafa Fikriyyah
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 1 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i1.5771

Abstract

Post-harvest management is essential because it will affect the final results. Post-harvest management products can be classified as simplicia because the stages include wet sorting, washing, draining, changing shape, drying, packaging, and storage. These steps must be paid attention to to ensure the content of active compounds in simplicia. The Bejo Bintang Toedjoe herbal garden at the Plalangan Gunungpati sub-district is managed by women from the Plalangan sub-district, both housewives and workers. Community service was implemented by preparing and making leaflets/brochures, conducting site surveys, conducting pretests and posttests, and monitoring and evaluating the practical results. This activity was attended by 25 participants, not only participants from the managers of the Bejo Bintang Toedjoe herbal garden but also residents from representatives of several community associations. The discussion session was opened after the counseling had been delivered. After the discussion session is finished, it continues with practice. The results of the pretest analysis showed that most participants still need to learn the effect of direct heating with sunlight for drying medicinal plant materials. Some participants also needed to learn that the tools used to cut medicinal plant materials were stainless steel. The posttest results showed that there was an increase in knowledge after conducting counseling and post-harvest management practices of medicinal plants.
Co-Authors Amalina Firdaus Amaliyah Ayu Nurfitriani Anita Dwi Puspitasari Aristya Kurniasih Awal Prichatin Kusumadewi Aysah Safitri Budiarti, Aqnes Budiarti Cicih Sumiarsih Cicih Sumiarsih Dewi Andini Kunti Mulangsri, Dewi Andini Kunti Dwi Lutvi Alviani Edy Meiyanto Erika Indah Safitri Esa Evinda Fatimatuz Zahroh Fatimatuz Zahroh Fauzizah, Nisa Ferry Sandra Fini Hartanti Fitriasih Fitriasih Fitriasih Fitriasih Hanik Rohmatul Maghfiroh Ibrahim Arifin Ibrahim Arifin Jenie, Riris Istighfari Komariyatun, Siti Laili Nailul Muna Laili Nailul Muna Lalu Ksatria D.S. Lilis Rejeki Lina Wahyuni Lina Wahyuni Lusyana Setiawati Marwan Masita Nur Amalia Putri Mufrod Mufrod Mutia Rahmatun Nenni Pratiwi Nenni Pratiwi Nilam Eka Putri NUR AINI Nur Kussamawari Ardian Nur Rahayu Fitriana Nurul Hidayati Parusiza, Intan Meyta Pia Annisa Pramesti Dewi Ririn Lispita Wulandari Riris Istighfari Jenie risha fillah fithria Rumiyati Rumiyati Salsabila, Unik Hanifah Salsabilla Putri Buana Pasha Shafa Fikriyyah Siti Komariyatun Siti Mega Komariah Siti Mega Komariyah Siti Nurikha Siti Wahidatun Nisa Sri Susilowati Susilowati Sugiyono - Syahrul Iqbal Setiawan Ulya Felasufah Umroh Mahmudah Umroh Mahmudah Yance Anas Yuni Antika