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All Journal Jurnal Kedokteran Diponegoro JPKMI (Jurnal Publikasi Kesehatan Masyarakat Indonesia) Journal of Community Empowerment for Health
Ari Budi Himawan
Department Of Public Health, Faculty Of Medicine, Universitas Diponegoro, Semarang, Indonesia
Humanities Dentistry Education Environmental Science Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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BERBAGAI FAKTOR RISIKO KEJADIAN TB PARU DROP OUT ( Studi Kasus di Kabupaten Jepara dan Pati) Himawan, Ari Budi; Hadisaputro, Suharyo; Suprihati, Suprihati
Jurnal Publikasi Kesehatan Masyarakat Indonesia Vol 2, No 1 (2015): April 2015
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpkmi.v2i1.2711

Abstract

AbstrakTB masih menjadi beban yang tinggi bagi masalah kesehatan di Indonesia yang menduduki peringkat ke-4 dunia dalam kejadian TB. Drop out merupakan salah satu penyebab terjadinya kegagalan pengobatan yang meningkatkan kemungkinan terjadinya MDR TB. MDR TB memerlukan biaya pengobatan lebih banyak dan waktu yang lebih lama. Tujuan penelitian adalah untuk menjelaskan pengaruh karakteristik individu dan lingkungan sebagai faktor risiko kejadian TB DO.Penelitian ini dilakukan secara observasional analitik dengan desain kasus kontrol dengan ditunjang analisa kualitatif. Jumlah subyek 70 orang, dengan rincian 35 kasus TB DO dan 35 kontrol( menyelesaikan pengobatan) yang tercatat antara tahun 2012-2013, dipilih secara consecutive sampling. Analisis data secara bivariat dengan uji chi Square dan multivariat dengan uji regresi logistik.Faktor risiko kejadian TB DO yang terbukti yaitu kurangnya pengetahuan tentang TB ( OR =78,6, 95% CI=11,697-528,218 ,p=0,000), pengalaman merasakan ESO ( OR=6,338, 95% CI=1,279-31,420,p=0,024), dan menggunakan obat tradisional (OR=7,451, 95% CI=1,315-42,209, p=0,023). Variabel yang tidak terbukti adalah umur, jenis kelamin, pekerjaan, penghasilan, tingkat pendidikan, akses menuju tempat pengobatan).Faktor risiko kejadian TB DO adalah kurangnya pengetahuan tentang TB, pengalaman merasakan ESO dan menggunakan obat tradisional. Kata-kata Kunci : TB DO, Efek samping obat, obat tradisional AbstractTuberculosis is still a high burden for health problems in Indonesia, which was ranked 4th in the worl . Drop out TB treatment was noted as one of the causes  that related to treatment failure, which is more risk to be MDR. MDR TB treatment will take more cost and time to cure it . The purpose of study was to investigate the risk factors, individual characteristics and environment, for incidence of TB DO. The study using analytic observational case-control design and enhanced by qualitative analysis. There are 70 subjects consists  of 35 cases of TB defaulter and 35 controls (complete treatment ) that reported between 2012 and 2013, consecutive sampling was used to selected respondent. Bivariate analysis using chi Square test and logistic regression for multivariate analysis. Multivariate analysis show that risk factors for TB DO include  lack of knowledge about TB ( OR = 78.6 , 95 % CI = 11.697 to 528.218 , p = 0.000 ) , the experience drug side effect ( OR = 6.338 , 95 % CI = 1.279 to 31.420 , p = 0.024 ) , and using traditional medicine (OR = 7.451 , 95 % CI = 1.315 to 42.209 , p = 0.023 ) . Elder age , sex male , occupation , lower income , level of education and access were not associated for TB DO. Risk factors for  TB DO is a lack of knowledge about TB , the experience side effect medicine and using traditional medicine . Keywords : TB DO , side effect of drug , traditional medicine
EFFECT OF MOMORDICA CHARANTIA FRUIT ETHANOLIC EXTRACT ON MALONDIALDEHYDE (MDA) LEVEL IN BLOOD OF SPRAGUE-DAWLEY RATS INDUCED BY 7,12-DIMETHYLBENZ[A]ANTHRACENE Ongky Surya Wijaya Hendro; Eka Yudhanto; Ari Budi Himawan; Dea Amarilisa Adespin
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 1 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i1.31226

Abstract

Background: Cancer is a type of disease with a high rate of diagnostic cases. The real cause of cancer remains unknown. Free radicals can cause cancer by DNA’s gen mutation. 7, 12- Dimethylbenz[a]anthracene (DMBA) is often used for researching carcinogenesis. Many types of research have used natural substances as supportive cancer therapies including Momordica charantia (bitter melon). Malondialdehyde (MDA) is one of the oxidative damage biomarkers which can significantly increase, especially on breast cancer patients. The success of therapy on a breast cancer patient is shown by decreasing MDA levels in the blood. Aim: To investigate the effect of Momordica charantia fruit ethanolic extract on malondialdehyde levels in the blood of Sprague Dawley rats induced by 7,12- Dimethylbenz [a] anthracene. Methods: This study was a true experimental randomized post-test only with control group design on rats that divided into two groups: X1 given DMBA induction only and X2 given DMBA induction with Momordica charantia fruit ethanolic extract by feeding tube with  200mg/kgbw/day for 14 days. Results: The mean of MDA level in group X1 = 0,83±0,32 and in group  X2 = 0,30±0,19. The result of the normality test of data using the Shapiro-Wilk test obtained abnormal distribution data for one of the groups. The result of independent-samples T-Test showed a significant difference with P = 0,001. Conclusion: There was an effect of Momordica charantia fruit ethanolic extract on MDA level in the blood of Sprague-Dawley induced by 7,12- Dimethylbenz[a]anthracene.
The Correlation Between The Use Of Face Moisturizers On The Incidence Of Acne Vulgaris Due To Masks Ashauma Aksanul Muttaqin; Ari Budi Himawan; Lusiana Batubara; Widyawati Widyawati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 4 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i4.35080

Abstract

Background: Acne vulgaris or widely known as acne, is a skin disease in the form of inflammation of the pilosebaceous unit characterized by the appearance of comedones, papules, pustules, and nodules. Due to the Coronavirus disease 2019 (COVID-19) pandemic, masks have become personal protective equipment (PPEs), commonly used by health workers and the general public. The combination of friction, repeated pressure, sweat, or stress on the skin from wearing the mask causes acne or an exacerbation of existing acne. Meanwhile, the use of facial moisturizer can maintain skin moisture and help the repair process of the structure of the skin barrier.Objective: This study aims to determine the relationship between the use of facial moisturizers and the incidence of acne vulgaris due to masks.Methods: This study is an analytical observational study with a cross-sectional design. The subjects in this study amounted to 44 people who were nurses at the Diponegoro National Hospital who had approved the informed consent form, filled out a complete questionnaire, and included the research criteria. The research sample was selected using purposive sampling. The diagnosis of acne vulgaris was made by doctor-in-charge based on the subject's face photo. The statistical test used is Fischer's Exact Test.Results: Based on data analysis using Fischer's Exact Test, the results showed no significant relationship between the use of facial moisturizers and the incidence of acne vulgaris due to masks with a p-value = 0.722 (p>0.05).Conclusion: There is no relationship between the use of facial moisturizers with the incidence of acne vulgaris due to masks.
Knowledge and behavior of elementary school children concerning soil transmitted helminth infections Annisa Aarts; Ari Budi Himawan; Marloes A van Bokhoven; Job FM Metsemakers; Tri Nur Kristina
Journal of Community Empowerment for Health Vol 3, No 3 (2020)
Publisher : Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jcoemph.54417

Abstract

Soil transmitted helminth infections (STHI) are prevalent among elementary school children in Indonesia. The nutritional impairments that an infection can cause have their consequences for the children’s development and health. This study aimed to determine children’s knowledge and behaviour in relation to the prevalence of STHI among elementary school children in Jepara, a rural regency in Indonesia. The study intended to evaluate the effectiveness of the current elimination program for STHI in this area. A cross-sectional study was conducted among 132 children from eight elementary schools in Mlonggo, Jepara. The research population consisted of children aged eight to ten years old. During September and October 2018, the research population was obtained by consecutive sampling. Information about the children’s knowledge and behaviour regarding STHI was collected using a questionnaire. Stool samples were collected to determine STHI prevalence. Analysis was done using chi-squared and Spearman’s rho tests. Out of 132 children examined, no children had STHI. Scores on STHI knowledge were most often low (51.5%), while scores on behaviour were mostly average (67.4%). Statistical analysis showed that residence was significantly associated with the level of knowledge about STHI (P = 0.007). Additionally, gender (P = 0.002) and a previous STHI (P = 0.041) were significantly associated with the children’s behaviour concerning STHI. This study revealed inadequate knowledge and behaviour concerning STHI in elementary school children in Mlonggo, Jepara. Even though the prevalence of STHI was 0% in the study population, a proper health education program to teach children about STHI is still necessary.
Co-Authors Annisa Aarts Ashauma Aksanul Muttaqin Dea Amarilisa Adespin Eka Yudhanto Job FM Metsemakers Lusiana Batubara Marloes A van Bokhoven Ongky Surya Wijaya Hendro Suharyo Hadisaputro Suprihati - Tri Nur Kristina Widyawati Widyawati