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All Journal Bioscience Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Bioedukasi: Jurnal Pendidikan Biologi Jurnal Pendidikan Biologi Indonesia DIDAKTIKA BIOLOGI: Jurnal Penelitian Pendidikan Biologi Biosaintifika: Journal of Biology & Biology Education JURNAL LENTERA PENDIDIKAN PUSAT PENELITIAN LPPM UM METRO Seminar Nasional Peningkatan Mutu Pendidikan Sinar Sang Surya: Jurnal Pusat Pengabdian kepada Masyarakat EDUBIOLOCK PROSIDING SEMINAR NASIONAL PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT (SNPPM) UNIVERSITAS MUHAMMADIYAH METRO
Rasuane Noor
Universitas Muhammadiyah Metro
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Neuroscience Physics Public Health Social Sciences

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Cytotoxicity of α-terpineol in HeLa cell line and its effects to apoptosis and cell cycle Mustofa, Rasuane Noor Indwiani Astuti
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 01 (2014)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (649.907 KB) | DOI: 10.19106/JMedScie004601201401

Abstract

α-Terpineol is a natural compound of terpenoid alcohols class. However, it can be synthesizedfrom α-pinene of turpentin content. α-Terpineol has been reported as potential anticancer agentdue to its activity on inhibition of cells growth and induction of tumor cell death. However, itsanticancer activity in HeLa cervical cancer cells line has never been studied, yet. The aim of thisstudy was to evaluate the cytotoxicity of α-terpineol and its effects to apoptosis and cell cycle.This was a quasi-experimental study with post-test only with non-equivalent control groupdesign. Cytotoxicity of á-terpineol was evaluated using MTT cell viability assay. The effect of α-terpineol on cell apoptotis was tested using acridine orange-ethidium bromide staining method,whereas its effect on cell cycle was evaluated by flowcytometry method. The results showedthat α-terpineol had cytotoxicity against HeLa cell with an IC50 value about 12.46 μg/mL.Furthermore, α-terpineol induced the HeLa with an IC50 value about 13.12 μg/mL. Cell accumulationat G1 phase during cell cycle after incubation with α-terpineol (52.78)was observed. In conclusion,α-terpineol is potential as an anticancer due to its ability to induce cell apoptosis and to inhibitthe cell cycle at G1 phase.
STUDI KEANEKARAGAMAN KUPU-KUPU DI BANTARAN SUNGAI BATANGHARI KOTA METRO SEBAGAI SUMBER BELAJAR BIOLOGI MATERI KEANEKARAGAMAN Suharno Zen, Rasuane Noor
Bioedukasi Jurnal Pendidikan Biologi Vol 6, No 1 (2015)
Publisher : UNIVERSITAS MUHAMMADIYAH METRO

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Abstract

Abstract: Butterflies are insects that have a very important role in the ecosystem is as a helper in the pollination in plants. In addition butterfly can also be used as a bio-indicator to changes in environmental quality since butterflies are very sensitive to changes in the ecosystem. The existence of butterflies are under threat at this time step and extinction, this is due to the many forests are converted into other land. Diminishing forests and lands turned into settlement and agriculture. Butterfly existence will depend habitat. Butterfly habitat with the amount of food available is quite the diversity of butterflies is high.The aim of research to determine the diversity of butterflies in Batanghari River Plate in Metro City, the research method used is survey method with purporsive sampling. Butterfly collection done by sweeping follows the line transect technique is applied randomly along the 1000 m. After completion of the identification process we then held classification process. Species diversity index (H) is calculated using the Shannon-Wiener formula. Results of the study found as many as 23 species of butterflies of 5 familia, with the most dominant species is Eurema alitha as much as 136. The diversity of butterflies in the Batanghari River Plate in City Metro categorized bit or lower because it has the value H1 <1.
PENYUSUNAN LEMBAR KERJA PESERTA DIDIK (LKPD) BIOLOGI SMA MELALUI STUDI KEANEKARAGAMAN MAKROFUNGI DI RESOR WAY KANAN BALAI TAMAN NASIONAL WAY KAMBAS Sutaningsih, Ida; Noor, Rasuane
Bioedukasi Jurnal Pendidikan Biologi Vol 6, No 2 (2015)
Publisher : UNIVERSITAS MUHAMMADIYAH METRO

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Abstract

Way Kanan Resort is one part of the Way Kambas National Park with an area of ± 40,000 Ha. Way Kanan Resort often found growing makrofungi, but so far no data are reported on a wide macrofungi species and their habitats. The aim of this study was to determine the species and diversity macrofungi  in Way Kanan Resort, and to develop research as a learning resource in the form of LKPD (student sheet) High School Biology Basidiomycota fungus material.This study used purposive sampling method with squared technique. The study was conducted on 26 until January 29, 2015. Data collection macrofungi The Way Kanan Resort area with extensive observations of ± 4 Ha and carried out data collection on 4 squares sampling. As supporting data, performed also a measurement of environmental parameters such as temperature, humidity and pH in each squared. Collecting data about the feasibility of learning resources LKPD measured using a questionnaire expert testing of the presentation material and design LKPD.These results indicate there are 26 species in the macrofungi Way Kanan Resort Way Kambas National Park with the total number of individuals as much as 980 macrofungi. Macrofungi great diversity index using diversity index test ShannonWienner throughout squared observations is 1.345474 with diversity are criteria. Feasibility study source LKPD theoretically has a score of 3-5 on each statement in the questionnaire design and presentation of the material as well as the percentage LKPD vulnerable feasibility has a score of 70% -90% with an average percentage of 80% which indicates LKPD classified as strong criteria. Kata Kunci ; Makrofungi, Resort Way Kanan, student sheets (LKPD) 
AKTIVITAS SITOTOKSIK SENYAWA Α-TERPINEOL PADA CELL LINE KANKER LEHER RAHIM (SEL HeLa) SEBAGAI SUMBER BELAJAR BIOLOGI MATERI POKOK BIOLOGI SEL Noor, Rasuane
Bioedukasi Jurnal Pendidikan Biologi Vol 3, No 2 (2012): Nopember 2012
Publisher : UNIVERSITAS MUHAMMADIYAH METRO

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Abstract

α-terpineol is a compound of the class of  terpenoid  alcohols  derived  from natural  materials, α-terpineol can be synthesized from  α-pinene  from  turpentin content of extracts derived  from  the sap of  pine  trees  (Pinus merkusii). α-terpineol has been reported as a natural compound that has potential as anticancer agent. Objectives of research:  In general, to assess the activity of α- terpineol  compounds  against  HeLa  cells  and  the   possible  mechanism,  whereas  specifically  assessing  cytotoxic  activity. Methods: This was a quasi-experimental study using post-test only with non-equivalent control group design.  This study was conducted on HeLa cells by administering α-terpineol. Observations  cytotoxic   activity assay was performed using MTT assay method. Results: α -terpineol was cytotoxic against HeLa cells with IC50 of 12,46 μg/mL, therefore this compound was a potential anticancer   Kata kunci :  α-terpineol, sitotoksik, HeLa, kanker leher rahim 
Red dragon fruit (Hylocereus costaricensis Britt. Et R.) peel extract as a natural dye alternative in microscopic observation of plant tissues: The practical guide in senior high school Wagiyanti, Heni; Noor, Rasuane
Jurnal Pendidikan Biologi Indonesia Vol 3, No 3 (2017): NOVEMBER
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (932.381 KB) | DOI: 10.22219/jpbi.v3i3.4843

Abstract

Prepared slide of plant tissue needs to be staining to facilitate observations under microscope. Laboratorium activities in schools usually use synthetic dyes which expensive and can be damaged the student. Therefore the exploration of alternative dyes need to be established, such as utilizing of red dragon fruit (Hylocereus castaricensis Britt. Et R.). This study aims to (1) find out the best concentration of dragon fruit peel extract for staining plant tissue prepared slide and (2) to develop the practical guide related to plant tissue observation. The qualitative research used different concentration  of red dragon fruit peel extract, namely: 30%, 40%, 50%, 60%, 70%, 80%, 90%, and 100% with 3 repetitions. Data were obtained from observation photos of prepared slide. The result showed that the most contrast prepared slide was used red dragon fruit extract in 60% concentration. The result use to arrange practical guide in observation of plant tissues which is validated by material expert. The validation result showed “very good” criteria (86.01%).
PENGEMBANGAN MODUL PRAKTIKUM BOTANI TUMBUHAN RENDAH MELALUI IDENTIFIKASI MAKROALGA KAWASAN PESISIR BARAT LAMPUNG Asih, Triana; Khayuridlo, M.; Noor, Rasuane
Didaktika Biologi: Jurnal Penelitian Pendidikan Biologi Vol 2, No 2 (2018): DIDAKTIKA BIOLOGI
Publisher : Universitas Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/dikbio.v2i2.1244

Abstract

Berdasarkan pengamatan dosen pengampu mata kuliah Botani Tumbuhan Rendah Program Studi Pendidikan Biologi Universitas Muhammadiyah Metro Tahun Ajaran 2016/2017, peserta didik mengalami kebingungan saat menentukan tumbuhan makroalga yang digunakan sebagai sampel identifikasi pada saat praktikum lapangan, sehingga hasil belajar peserta didik rendah. Tujuan dari penelitian ini adalah mengembangkan dan menghasilkan modul praktikum mata kuliah Botani Tumbuhan Rendah yang valid, praktis, dan efektif. Model R&D yang digunakan merujuk pada Sugiyono yang dibatasi sampai 7 tahapan, yaitu: analisis potensi dan masalah, pengumpulan data, desain produk, validasi desain, revisi desain, uji coba produk/uji efektivitas, dan revisi produk. Tahapan potensi masalah menggunakan lembar wawancara, tahapan validasi melalui instrumen penilaian menggunakan angket skala penilaian, dan uji efektivitas modul praktikum menggunakan Quasi Eksperimen. Hasil penelitian menyatakan bahwa produk yang dikembangkan valid dengan nilai rata-rata dari ahli desain dan materi 84% dengan kriteria sangat kuat, rata-rata uji kepraktisan 92% dengan kriteria sangat kuat, dan teruji efektif bahwa hasil belajar pada kelas eksperimen lebih besar dari kelas kontrol. Based on the observation of lecturer’s Low Plants Botany at Biology Education Study Program in University of Muhammadiyah Metro,the students were confused when determining macroalgae plant that used as sample in doing the field practicum, so that the students’ outcome was low. The purpose of this study was to develop and produce a valid, practical and effective practicum module for Low Plants Botany Subject. The R&D model used refers to Sugiyono which was limited to 7 stages: potential and problems analysis, data collection, product design, design validation, design revision, product test/effectiveness test, and product revision. The stage of potential and problem analysis used the interview sheet, the stages of validation used the assessment scale questionnaire, the effectiveness test of the practicum module carried out through Quasi Experiment. The results of the study showed that the developed product was valid with the average value of design and material experts was 84% (very strong), the average of practicality test was 92% (very strong), and the practicum module was tested effectively which showed that the learning outcome in the experimental class was higher than in the control class.
Biodiversity and Potential Use of Macro Algae in Pesisir Barat Lampung Asih, Triana; Khayuridlo, Muhammad; Noor, Rasuane; Muhfahroyin, Muhfahroyin
Biosaintifika: Journal of Biology & Biology Education Vol 11, No 1 (2019): April 2019
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1810.624 KB) | DOI: 10.15294/biosaintifika.v11i1.16532

Abstract

Pesisir Barat Regency in Lampung has abundant marine biological wealth that has not been widely known and utilized by the community, one of them is macro algae. The objectives of the research were to identify the types of macro algae and to explains the potential use of macro algae in the Pesisir Barat Lampung Region. The study used cruise method. The findings were identified by experts to validate the results of classification, morphology, and qualitative studies regarding the potential use and benefits of macro algae. From the results of this study, 15 species of macro algae were found on Tanjung Setia Beach included; 3 species of green algae (Chlorophyta) consist of  Halimeda opuntia L., Caulerpa racemosa F., Ulva lactuca L .; 7 species of brown algae (Phaeophyta) consist of  Padina pavonica L., Padina australis H., Sargassum vulgare C.A., Sargassum polycystum C.A., Turbinaria ornata J.A., Turbinaria ornata J.A., Fucus vesiculosus L.; and 5 species of red algae (Rhodophyta), consist of  Corallina officinalis L., Gigartina pistilla S., Gigartina disticha S., Gracilaria verrucosa, H., Rhodymenia pseudopalmat J.V.L.The benefits of this research for society to provide insight into the potential use of macro algae which can be utilized in many fields. For students, provide information on the biodiversity of macro algae in the sea.
MODUL PERTUMBUHAN TANAMAN AGLAONEMA BERBASIS MODIFIED INQUIRY UNTUK MENGEMBANGKAN KETERAMPILAN HIPOTESIS PESERTA DIDIK Asih, Triana; Suharno Zen, Suharno; Noor, Rasuane
JURNAL LENTERA [PENDIDIKAN PUSAT PENELITIAN LPPM UM METRO] Vol 6, No 1 (2021): June, 2021
Publisher : Lembaga Penelitian UM Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/jlpp.v6i1.1656

Abstract

Pemanfaatan Etnomedisin Dari Famili Zingiberaceae Pada Masyarakat Etnis Lampung Pesisir Kabupaten Tanggamus Kecamatan Semaka Provinsi Lampung Suharno Zen; Marlina Kamelia; Rasuane Noor
SEMINAR NASIONAL PENINGKATAN MUTU PENDIDIKAN Vol. 1 No. 1 (2020): Seminar Nasional Peningkatan Mutu Pendidikan
Publisher : Fakultas Keguruan dan Ilmu Pendidikan Universitas Samudra

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Abstract

Indonesia merupakan salah satu negara dengan hutan tropis terbesar dengan keanekaragaman tumbuhan yang tinggi. Selain keanekaragaman tumbuhan, Indonesia juga kaya dengan keanekaragaman Etnis dan budaya. Berbagai Etnis memanfaatkan tumbuhan sebagai etnomedisin dengan keunikan ramuan dan cara penyajiannya masing-masing (kearifan lokal). Penelitian ini bertujuan untuk menginventarisasi tumbuhan obat dari famili zingiberaceae, bagian yang digunakan dan cara meramu tumbuhan obat oleh masyarakat etnis lampung pesisir Tanggamus Provinsi Lampung. Metode pemilihan informan yang digunakan dalam observasi ini adalah metode “Purposive sampling”dan “Snowball sampling”, dalam hal ini menggunakan informan/orang yang dianggap paling tahu tentang tumbuhan dan orang yang dituakan (ulun tuha/natuha). Penentuan lokasi sampling berdasarkan etnis Lampung pesisir yang banyak berdomisili di 3 desa Kecamatan Semaka yaitu Desa Bangunrejo, Desa Sukaraja, dan Desa Kanoman. Hasil penelitian terdapat 13 spesies tumbuhan. Bagian tumbuhan yang digunakan sebagai bahan ramuan obat berupa rimpang/akar dan buah. Lokasi ditemukannya tumbuhan tersebar di pekarangan, ladang/kebun dan perbatasan hutan. Cara penggunaan tanaman obat dapat diminum/dimakan (pemakaian dalam), diusap, diparem dan dikompres (pemakaian luar). Tumbuhan tersebut dimanfaatkan sebagai bahan pangan/bumbu dapur, obat-obatan dan sarana ritual. Kajian botani menunjukkan famili Zingiberaceae lebih dominan dengan habitus herba. Kajian etnomedisin menunjukkan bahwa famili ini lebih cenderung digunakan dalam menambah nafsu makan, stamina, melahirkan. Kajian etnoekonomi memperlihatkan bahwa beberapa spesies telah memiliki nilai ekonomi dan ada juga yang tidak memiliki nilai ekonomi karena belum diperdagangkan. Kajian etnoantropologi menunjukkan bahwa beberapa spesies dari famili ini dipercaya dapat mengusir mahluk halus dan energi negatif.
The Influence of Bioinsektiidide Variation of Tuba Root Extract (Derris elliptica Roxb. Benth) On Phantsahm Mortality the Pest (Leptocorisa Acuta Thumberg) I Gede Warse; Handoko Santoso; Rasuane Noor
Bioscience Vol 3, No 1 (2019): Biology
Publisher : UNIVERSITAS NEGERI PADANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/0201931103757-0-00

Abstract

Leptocorisa acuta Thumberg is one of the pests that many rice farmers complain about. This pest can cause damage to rice plants while still young, so the results obtained are not optimal. Based on these problems it is necessary to use insecticides so that the pest can be controlled. Derris elliptica Roxb. Benth is one of the many plants that grow in Indonesia. The root of this plant has a chemical compound in the form of rotenone which has the potential as a bioinsecticide to eradicate pest parasites. The study was an experimental study using a completely randomized design method with three treatments and one control with 6 replications. The treatment dose in this study using root extract Derris elliptica Roxb. Benth. Bent: 8%, 10%, 12% and 0% control. Based on the Kruskal Wallis Test the results were x2calculate 10.88 > x2table 9.49 at a 0.05 in the Chi-square table, so that there was an effect of the variation of the bioinsecticide dose of root extract Derris elliptica Roxb. Benth the impact on mortality of the Imago Leptocorisa acuta Thumberg. Based on the average ranking of treatment at a dose of 12%: 6.7, a dose of 10%: 8.46, a dose of 12%: 8.76 and a control of 0%: 18, so it can be concluded that root extract Derris elliptica Roxb. Benth the most effective against the mortality of imago Leptocorisa acuta Thumberg was at a dose of 12%.
Co-Authors . Mustofa Achyani Achyani Achyani Achyani, Achyani Afiqah Khairunisa Agus Setiawan Agus Sujarwanta Agus Sujarwanta Agus Sutanto Arisiyantoro Arisiyantoro Ashuri Yahya Dasrieny Pratiwi Dewi Kurniawati Dini Arifah Eka Zulfitri Ervina Agustin Handoko Santoso Handoko Sntoso Handoyo Handoyo Hendra Panca Kusuma Heni Wagiyanti Hening Widowati HRA Mulyani HRA Mulyani I Gede Warse Ida Sutaningsih Ida Sutaningsih, Ida Indah Meika Sari Indwiani Astuti Khayuridlo, M. Khayuridlo, Muhammad Livia Indri Puasari M Rustam Rifai Marlina Kamelia Melda Ayu Priskilia Muhfahroyin Muhfahroyin Nisa Yulis Tika Putri Agustina Suharno Zen Triana Asih Triana Asih, Triana Wagiyanti, Heni Widya Sartika Sulistiani, Widya Sartika