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All Journal Jurnal Sain Veteriner Jurnal Veteriner Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan JBN (Jurnal Bedah Nasional) JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Indian Journal of Forensic Medicine & Toxicology Jurnal Rekonstruksi dan Estetik MEDICINUS
Iswinarno Doso Saputro
Departemen Bedah Plastik Rekonstruksi Dan Estetik, Fakultas Kedokteran, Universitas Airlangga/RSUD Dr. Soetomo, Surabaya
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Veterinary Other

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Journal : Folia Medica Indonesiana

 1 
EFFECT OF PLATELET RICH PLASMA (PRP) TO AUTOGENOUS BONE GRAFT Iswinarno Doso Saputro; Magda Rosalina Hutagalung; Siti Isya Wahdini
Folia Medica Indonesiana Vol. 53 No. 1 (2017): JANUARY - MARCH 2017
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (233.815 KB) | DOI: 10.20473/fmi.v53i1.5485

Abstract

Bone graft use in maxillofacial surgery is currently developing, though some problems still persist. One of promising solutions to the problems is application of platelet rich plasma which may accelerate soft tissue healing and bone formation. This study aims to provide basic understanding to the development of PRP application in bone healing where bone graft is applied on human maxillae. Bone defects were made on maxillae of albino rabbits, with an application of bone graft in control group and bone graft plus PRP in treatment group. Histopathological analysis was performed in both groups to assess osteoblast density and collagen tissue area. On day 21st, more osteoblast density and collagen area in treatment group are significantly observed (p<0.05, 95% confidence interval). Observations were made on hard callus formation. In conclusions, platelet rich plasma may increase density of osteoblast in rabbit maxillary bone graft.
Elevated Serum Transaminase (SGOT/SGPT) and Sepsis in Burn Patients in a Tertiary Hospital, Surabaya, Indonesia Iswinarno Doso Saputro; Lobredia Zarasade; Rifqi Kurniawan
Folia Medica Indonesiana Vol. 58 No. 2 (2022): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (766.638 KB) | DOI: 10.20473/fmi.v58i2.32865

Abstract

Highlights: There is no correlation between the increase of SGOT and sepsis. Correlation between the increase of SGPT and sepsis was significant founded.   Abstract: Burns trigger hypermetabolic stress reactions that cause inflammatory responses. When there is a sustained or increased hypermetabolic reaction, the inflammatory response can be life-threatening, such as sepsis, and significantly impact hepatic metabolic function. After burns, varying degrees of liver injury are usually associated with burn severity. This study determined the correlation between elevated serum transaminases (SGOT/ SGPT) and sepsis in burn patients at a tertiary hospital of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January 1, 2018, to December 31, 2020. This was a descriptive-analytic study with a retrospective cohort design. The data in this study included the demography of burn patients, causes of burns, inhalation trauma, burn severity, increased serum transaminase (SGOT/SGPT), mortality, and sepsis. This study found that the correlation between elevated serum transaminases (SGOT/SGPT) and sepsis was determined using the Spearman-Rho Rank statistical test. Burn patients with sepsis in the hospital were dominated by males (65.2%) and mostly aged 26-55 years (69.6%). The flame was found to be the highest cause of burns (80.4%), burn area above 20% (91.3%), the highest level of severity was major burn (91.3%), and no inhalation trauma (54.3%). In this study, there was an increase in SGOT of 69.6% and SGPT of 78.3%, with a mortality rate of 39.1%, with average inpatient days of 24 days. The correlation test between elevated serum transaminase (SGOT) and sepsis showed an insignificant relationship (p = 0.065, p> 0.05) with a correlation coefficient of 0.200. In contrast, the correlation between elevated serum transaminase (SGPT) and sepsis was significant (p=0.006, p<0.05) with a correlation coefficient of 0.296.
Co-Authors Agus Santoso Budi Arif Tri Prasetyo Aryati Dhitta Aliefia Noverta Dwi Murtiastutik Hasan, Helmia Hesty Aulia Palupi Huvi, Indira I Made Suka Adnyana Karimah, Azimatul Laras Puspita Ningrum Lobredia Zarasade Lobredia Zarasade Lynda Hariani Magda Rosalina Hutagalung Magda Rosalina Hutagalung Marelno Zakanito Medisa Primasari Muhaimin Rifa’i Muhammad Aulia U H Nadia Tamara Putri Nur Aida Priscilla Valentin N Rahel Yuana Sadikim Revita Widya Prasanti Rifqi Kurniawan Salsabilla Gina Rania Septin Mauludiyana Siti Isya Wahdini Sitti Rizaliyana Waode Fifin Ervina Willy Sandhika Wiwik Misaco Yuniarti Yoes Prijatna Dachlan