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All Journal Sari Pediatri Paediatrica Indonesiana Belitung Nursing Journal Jurnal Gizi Klinik Indonesia
Elisabeth Siti Herini
Bagian Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Gadjah Mada /RSUP Dr. Sardjito, Yogyakarta
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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Faktor Prognostik Kegagalan Terapi Epilepsi pada Anak dengan Monoterapi Agung Triono; Elisabeth Siti Herini
Sari Pediatri Vol 16, No 4 (2014)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (70.492 KB) | DOI: 10.14238/sp16.4.2014.248-53

Abstract

Latar belakang. Epilepsi merupakan salah satu penyakit neurologi utama pada anak. Banyak faktor yangmemengaruhi kegagalan monoterapi epilepsi pada anak sehingga akan berdampak pada keberhasilan terapiepilepsi secara keseluruhan.Tujuan. Mengetahui faktor prognostik yang dapat digunakan untuk memprediksi kegagalan monoterapiepilepsi pada anakMetode. Penelitian kasus-kontrol pada pasien epilepsi usia 6 bulan sampai dengan 18 tahun yang berobatke Poli Anak RSUP Dr. Sardjito tahun 2009. Kasus adalah pasien epilepsi yang gagal dengan monoterapidan kontrol adalah pasien epilepsi yang berhasil dengan monoterapi.Hasil. Didapat 120 pasien dengan 60 pasien kelompok kontrol dan 60 kelompok kasus. Dilakukan analisisunivariat pada masing-masing faktor prognostik. Berdasarkan analisis univariat didapatkan beberapa faktorprognostik kegagalan monoterapi, yaitu terapi epilepsi yang tidak segera, frekuensi serangan kejang sebelumterapi, status epileptikus, adanya defisit neurologis, dan adanya kelainan neurologi penyerta. Setelah dianalisissecara multivariat, faktor frekuensi serangan kejang sebelum terapi >10 kali (OR 14,196, IK95%:3,576-56,348; p<0,01) dan adanya kelainan neurologi penyerta (OR 18,977, IK95%:3,159-113,994; p<0,01 )merupakan faktor prognostik kegagalan monoterapiKesimpulan. Hasil penelitian ini menunjukkan bahwa anak epilepsi dengan serangan kejang lebih darisepuluh kali sebelum terapi dan adanya kelainan neurologi penyerta merupakan faktor prognostik kegagalanmonoterapi.
Postpartum lactation counseling and exclusive breastfeeding: analysis of the 2017 Indonesian Demographic and Health Survey Warantika Rikma Yuniarini; Elisabeth Siti Herini; Abdul Wahab
Paediatrica Indonesiana Vol 61 No 1 (2021): January 2021
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi61.1.2021.25-33

Abstract

Background The percentage of exclusive breastfeeding in Indonesia on 2018 dropped from 39.8% in infants aged 0 monthsto 15.3% in infants aged 5 months. According to the 2018 Indonesian Basic Health Research Survey (Riskesdas), an average of 37.3% of infants were exclusively breastfed until the age of 6 months. This rate is far from the target of 80% by Ministry of Health of Indonesia. Objective To assess for an association between postpartum counseling and the practice of exclusive breastfeeding in Indonesia. Methods This retrospective cohort study used data from the 2017 Indonesian Demographic and Health Survey (IDHS). The sample comprised 258 infants aged 6 months. Postpartum counseling and other variables were analyzed for possible associations with exclusive breastfeeding by Chi-square test; risk ratios (RR) with 95% confidence intervals (CI) were calculated. Logistic regression test was used to analyze for adjusted odds ratios. Results In 6 months period, the percentage of subjects who received postpartum counseling was 59.7% and who exclusively breastfed was 18.8%. There was no significant association between postpartum lactation counseling and exclusive breastfeeding. However, there were significant associations between exclusive breastfeeding and not using currently as well as maternal residence in rural areas. Conclusion Postpartum counseling on breastfeeding lacks a significant association with exclusive breastfeeding practice at 6 months of age. Therefore, the Ministry of Healthshould reevaluate the implementation of its counseling services.
Potentially predictive factors for hearing function improvement in pediatric cytomegalovirus infection therapy Agung Triono; Elisabeth Siti Herini; Braghmandita Widya; Dian Kesumapramudya Nurputra
Paediatrica Indonesiana Vol 61 No 5 (2021): September 2021
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi61.5.2021.235-9

Abstract

Background Symptomatic congenital cytomegalovirus (CMV) infection has an impact mainly on neurological sequelae, including sensorineural deafness. Because of the long-term impact, early treatment of CMV infection is mandatory. However, predictive factors for hearing function improvement in CMV infection therapy remain unexamined. Objective To evaluate potential predictive factors for hearing improvement in pediatric CMV infection therapy. Methods All medical record data of patients aged 0-6 years with CMV infection who completed a 6-week course of ganciclovir therapy or a combination of a 4-week course of ganciclovir and a 2-week course valganciclovir from January 2013 to December 2017 were collected. Age at onset of therapy, gender, gestational age, nutritional status, multi-organ involvement, and neurological symptoms were studied as potential predictive factors of hearing improvement in CMV therapy. The effectiveness of CMV infection therapy on improving hearing function was measured with the brainstem evoked response audiometry (BERA) test. Results BERA tests proportion in the right, left, and best ear showed significant improvement after therapy. All variables analyzed were not statistically significant as predictive factors for hearing improvement in CMV infection therapy. Conclusion Ganciclovir/valganciclovir therapy in CMV infection patients accounted for the improvement of hearing impairment. However, none of the assessed factors were considered predictive for improving hearing function in CMV infection therapy.
CAREGIVERS’ EXPERIENCE IN MEETING SELF-CARE NEEDS OF ADOLESCENTS WITH AUTISM SPECTRUM DISORDER: A QUALITATIVE STUDY Lilis Lestari; Elisabeth Siti Herini; Indria Laksmi Gamayanti
Belitung Nursing Journal Vol. 3 No. 4 (2017): July - August
Publisher : Belitung Raya Foundation, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (273.013 KB) | DOI: 10.33546/bnj.123

Abstract

Background: Autism spectrum disorder is a complex developmental disorder, which increased rapidly than other developmental disorders in the world. This complex disorder affects a child’s self-autonomy, which has become a challenge for their parents or caregivers. Objective: This study is to explore main caregivers’ experience to meet self-care needs of adolescents with autism spectrum disorder in Pontianak, West Borneo, Indonesia. Methods: This study employed a qualitative design with semi-structured in-depth interviews. Seven main caregivers who are living together and taking care of the adolescents with autism spectrum were selected using a purposive sampling. Triangulation was conducted to ensure the trustworthiness of this study, including interviews, observations of self-care activities, documents such as photos, learning reports, and field notes. Participants’ statements were recorded using a voice recorder, and then transcribed, coded, interpreted, and categorized to form main themes and sub-themes. Results: The study identified three main themes: 1) autonomy in self-care, 2) care effort, 3) feelings, supports, and expectations. These findings emphasize the potentials of the children with autism to be autonomous in their daily self-care. Conclusions: Adolescents with autism spectrum disorder can potentially meet the needs of their daily care independently. This article has been corrected with a separate erratum: https://doi.org/10.33546/bnj.1146
ASI sebagai faktor protektif terhadap autisme Kornelius Dandung Bawono; Elisabeth Siti Herini; Setya Wandita
Jurnal Gizi Klinik Indonesia Vol 8, No 4 (2012): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.18213

Abstract

Background: The prevalence of autism has risen in the last decades. Risk factors of autism remain controversial and were thought to be multifactorial. One hypothesis stated that it may be caused by leaky gut theory and long chain polyunsaturated fatty acid defi ciency. Optimal duration of breastfeeding has been proven to reduce risk of gastrointestinal infection and improve child’s cognitive ability.Objective: To study the protective effect of optimal duration of breastfeeding to reduce the risk of autism. Method: A matching case-control study was conducted in Yogyakarta and Magelang during 2008. Inclusion criteria of case group were all children with autism (diagnosed based on DSM-IV TR criteria), aged 3-10 years. Autistic children with distinct genetic disorder were excluded. Control group was matched on gender, age, and their residence. Breastfeeding pattern and other related information were obtained by direct interview. McNemar test, conditional multivariate logistic regression, and Maentel-Haenszel test were used to fi nd factors that are signifi cantly associated with autism.Result: There were 52 children with autism and 104 control subjects. The mean age was 5 years old. The analysis revealed that breastfeeding duration for less than 6 months was a signifi cant risk factor for autism (ORMH=2,05; RK 95%:1,03-5,01), as well as history of abnormal birth weight (OR=3,36; RK 95%:1,37-8,44). There was dose-effect gradient as breastfeeding duration affected risk of autism. There was no differences on the duration of exclusive breastfeeding between the two groups. Conclusion: Breastfeeding duration of less than 6 months was a signifi cant risk factor for autism.
Co-Authors Abdul Wahab Adeta Stefianti Isnoor Agung Triono Braghmandita Widya Indria Laksmi Gamayanti Kornelius Dandung Bawono Lestari, Lilis Melina Dian Kusumadewi Nurputra, Dian Kesumapramudya Setya Wandita Warantika Rikma Yuniarini Yusmiyati Yusmiyati