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All Journal Jurnal Veteriner Majalah Kedokteran Bandung Folia Medica Indonesiana Majalah Obstetri dan Ginekologi Syntax Literate : Jurnal Ilmiah Indonesia ISM (Intisari Sains Medis) : Jurnal Kedokteran Berkala Penelitian Hayati
Hamdani Lunardhi
Department Of Andrology, Faculty Of Medicine, Universitas Airlangga, Dr. Soetomo Hospital, Surabaya
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Veterinary Other

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Journal : Syntax Literate : Jurnal Ilmiah Indonesia

 1 
Factors Affecting The Outcome of in Vitro Fertilization (IVF) Fayka Putri Poempida; Jimmy Yanuar; Hamdani Lunardhi; Samsulhadi Samsulhadi; Relly Y. Primariawan
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.598 KB) | DOI: 10.36418/syntax-literate.v7i1.5780

Abstract

The high prevalence of infertility motivated researchers to find a solution, henceforth In Vitro Fertilization was invented. Factors that affect the outcome of IVF may include sperm analysis, maternal Body Mass Index (BMI), maternal smoking habits, endometriosis, and maternal age. However, there are ongoing debates about the role of said factors regarding the outcome of IVF. The objective of this research is to analyze those factors. This research is a Case-Control study with an analytical observational design. Data were retrieved from patients’ medical records undergoing IVF in Graha Amerta Fertility Clinic from January 2019-October 2020. First, the Chi-Square Test revealed sperm abnormality (p=0.212), Maternal BMI (p=0.427), endometriosis (p=0.067), meaning there was no connection with the outcome of IVF. Simultaneously, maternal age (p=0.037) showed a connection with the outcome of IVF. From the Binary Logistic Regression Test, maternal age 36-40 years old (p=0.044) affects the outcome of IVF significantly. Concurrently maternal BMI, endometriosis, and sperm abnormality have p value>0.05 meaning it is insignificant to the outcome of IVF. This research concluded that sperm abnormality, maternal BMI, and endometriosis do not affect the outcome of IVF. There was no data about maternal smoking habits. Whilst maternal age affects the outcome of IVF. Conclusion: This research concluded that sperm abnormality, maternal BMI, and endometriosis do not affect the outcome of IVF. There was no data about maternal smoking habits. Whilst maternal age affects the outcome of IVF.
Hubungan Usia Ibu, Jumlah AFC, dan Total Pemberian Gonadotropin terhadap Kualitas Embrio pada Program Fertilisasi In Vitro di Klinik Fertilitas Graha Amerta RSUD Dr. Soetomo Surabaya Periode 2018 – 2019 Chitra Devi Paramita Prasetyawati; Budi Santoso; Hamdani Lunardhi; Hendy Herdarto; Ashon Sa’ad
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.598 KB) | DOI: 10.36418/syntax-literate.v7i1.5742

Abstract

Fertilisasi In Vitro merupakan metode untuk mendapatkan kehamilan pada pasangan infertil. Meskipun dengan FIV, angka keberhasilan kehamilan masih cukup rendah yang tentu tidak terlepas dari pengaruh kualitas embrio yang didapatkan. Banyak faktor yang dapat mempengaruhinya, beberapa contohnya adalah usia ibu, jumlah AFC, dan total pemberian gonadotropin. Namun, penelitian mengenai ini masih terbatas terkait literatur dan informasinya. Mengetahui hubungan usia ibu, jumlah AFC, dan total gonadotropin terhadap kualitas embrio pada program FIV di Klinik Fertilitas Graha Amerta Periode 2018- 2019. Penelitian ini menggunakan rancangan cross sectional dengan metode total sampling. Bahan penelitian dari rekam medis pasien yang menjalami program FIV di Klinik Fertilitas Graha Amerta periode 2018-2019. Dari 52 pasangan yang menjalani FIV didapatkan hasil p-value antara usia dengan kualitas embrio baik hari ke-3 0,020, degenerasi 0,003, kualitas embrio baik hari ke-5 0,007, buruk 0,048. AFC dengan kualitas embrio baik hari ke-3 0,000, degenerasi 0,001, kualitas embrio baik hari ke-5 0,001. Total gonadotropin dengan kualitas embrio hari ke-3 dan ke-5 <0,05. Biochemical pregnancy dengan kualitas embrio baik hari ke-3 0,013. Penelitian ini membuktikan bahwa usia ibu dan jumlah AFC berhubungan dengan kualitas embrio. Total pemberian gonadotropin tidak berhubungan dengan kualitas embrio. Namun, apabila diteliti secara bersamaan terdapat hasil pengaruh signifikan secara simultan antara usia ibu, jumlah AFC dan total pemberian gonadotropin terhadap persentase kualitas embrio baik pada hari ke-3 dan hari ke-5.
Co-Authors Amarudin Amarudin Ashon Sa’ad Ashon Sa’adi Aucky Hinting Aucky Hinting Aucky Hinting Audia Mumtaz Rifasky Ayang Halim Budi Santoso Chitra Devi Paramita Prasetyawati Doddy M Soebadi Faizah, Zakiyatul Fayka Putri Poempida Gede Wira Buanayuda Ginting, Aucky Hendy Herdarto I'tishom, Reny Indra Gusti Mansur Indra Gusti Mansur Jimmy Yanuar Lutfi Hardiyanto Mansur, Indra Gusti Ninik Darsini Nur Hafiz Ramadhona Puspa Wardhani R. Haryanto Aswin R. Haryanto Aswin Ramadhona, Nur Hafiz Relly Y. Primariawan Rina Yudiwati Samsulhadi Samsulhadi Sukarjati Sukarjati Supardi Supardi Supardi Supardi Suyono, Seso Sulijaya Wahyuning Ramelan Widjiati Widjiati