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Pemanfaatan Penawar Sampai (Tinospora crispa L.) sebagai Tanaman Obat Tradisional oleh Suku Dayak Ngaju Natalia Sri Martani; Fatmaria Fatmaria
Jurnal Pharmascience Vol 7, No 2 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i2.8799

Abstract

 Kehidupan sub rumpun Suku Dayak Ngaju di Kalimantan Tengah sangat bergantung pada hutan dan alam. Masyarakatnya menggunakan berbagai obat-obatan tradisional yang bermanfaat, salah satunya adalah tanaman penawar sampai (Tinospora crispa L.). Penelitian ini bertujuan mengeksplorasi tanaman T. crispa sebagai obat tradisional Suku Dayak Ngaju. Metode yang digunakan ialah penelitian eksploratif dari Basir, para ahli pengobatan tradisional Suku Dayak Ngaju. Pemilihan Basir menggunakan metode snowball sampling. Hasil penelitian ini menunjukkan bahwa T. crispa yang digunakan oleh masyarakat Suku Dayak Ngaju secara empiris digunakan sebagai antihipertensi; menunjang diabetes agar terkontrol; pengobatan penyakit kulit; melawan alergi; meningkatkan selera makan; penyembuhan luka; sakit kuning (hepatitis); penyembuhan rematik; antimalaria; menstimulasi saraf; dan antidiare. Kesimpulan penelitian ini bahwa T. crispa merupakan tanaman obat tradisional yang memiliki banyak manfaat. The life of the sub ethnic of Dayak Ngaju Tribe in Central Kalimantan is very dependent on the forest and nature. People use a variety of traditional medicines are beneficial, one of which is the penawar sampai (Tinospora crispa L.). The research objective to explore the utilization of the T. crispa as a medicinal plant traditional Dayak Ngaju Tribe. The method used is exploratory research of Basir, the traditional healers from Dayak Ngaju Tribe. The selection of Basir using the method of snowball sampling. The results of this study indicate that the antidote to that used by the people of Dayak Ngaju Tribe empirically used as an antihypertensive; support to controlled diabetes; a skin disease that can be treated; fight allergies; improves appetite; wound healing; yellow fever (hepatitis); the healing of rheumatism; antimalaria; stimulates the nerves and anti diarrhea. The conclusion of this study that the antidote to is a traditional medicinal plant that has many benefits.Keywords: Penawar Sampai, Tinospora crispa L., Medicinal Plants, Dayak Ngaju Tribe
COMMUNITY KNOWLEDGE, ATTITUDES, AND BEHAVIOR TOWARDS SOCIAL DISTANCING POLICY AS PREVENTION TRANSMISSION OF COVID-19 IN INDONESIA Budi Yanti; Eko Mulyadi; Wahiduddin Wahiduddin; Revi Gama Hatta Novika; Yuliana Mahdiyah Da’at Arina; Natalia Sri Martani; Nawan Nawan
Indonesian Journal of Health Administration (Jurnal Administrasi Kesehatan Indonesia) Vol. 8 (2020): SPECIAL ISSUE
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jaki.v8i0.2020.4-14

Abstract

Background: Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV2 recently became a pandemic worldwide, such as in Indonesia. Social distancing is one of the recommended mitigations to reduce the risk of disasters, such as morbidity and mortality caused by COVID-19. Community compliance with social distancing is a part of the pandemic control.Aims: This study identified knowledge, attitudes, and behavior towards the prevention of SARS-CoV-2 transmission through social distancing during COVID-19 pandemic among Indonesian community.Methods: This descriptive study applied a cross-sectional design and distributed closed questions with online  questionnaire randomly to 34 provinces in Indonesia on social media networks and e-mail. This study successfully collected 1,102 respondents from 29 provinces in Indonesia. The data were analyzed descriptively by calculating frequency, percentage, and cross-tabulation.Results: This study had successfully identified  99%, 59%, and 93% of respondents with good knowledge, positive attitudes, and good behavior respectively towards  social distancing. Among the respondents who had good knowledge showed positive attitudes (58.85%) and good behavior (93.3%). The respondents who had positive attitudes showed good behavior (96.7%).Conclusion: Indonesian community had good knowledge, attitude and behavior towards social distancing as a way to prevent the virus transmission. This strongly supports disaster mitigation in controlling the COVID-19 pandemic in Indonesia. Keywords: attitudes, behavior, COVID-19, knowledge, social distancing.
Literature Review: Analisis Senyawa Aktif Ekstrak Dan Fraksi Tanaman Berpotensi Sebagai Antiplatelet Virena Audelia Rambang; Fatma Ria; Natalia Sri Martani
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 3 (2021): Herb-Medicine Journal Juli 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i3.9436

Abstract

ABSTRACT Stroke is still the main cause of morbidity and mortality in the world. Research found "aspirin resistant" in 5-60% of cases, it’s necessary to develop researches related to antiplatelet therapy. In the antiplatelet research on plant extracts, some were significant and some weren’t. To determine active compound of plant extracts, fractions, mechanism of action, extraction method, isolation methods of active compounds with antiplatelet activity. Literature studies with a systematic approach, data from original articles in GoogleScholar, PubMed. Obtained 32 literatures through data quality analysis and topic suitability. Data synthesis using PICO method. 30 journals significantly have antiplatelet activity, 2 weren’t, the most found compounds were flavonoids, quercetin. Mechanism of action as an antiplatelet, antithrombotic. Extraction methods maceration, reflux, juice, sonication, soxhlet, distillation. The isolation methods using CC, HPLC, TLC, NMR. Conclusion: Insignificant results are from AGE and raw, boiled, fried garlic, both tested in vivo. Journals that significantly have antiplatelet results are from extracts of strawberries, grape seeds, Allium sp., Bay leaves, mango peel, tomatoes, Hawthorn, C.aromatica Salisb., Red ginger, G.verrucosa, S.polycystum, olive leaves, M.alba, P.baumii, R.vernicflua, A.shikokiana, katuk leaves, tempuyung leaves, red cabbage, M.obovata, lempeni leaves, kajajahi leaves, starfruit leaves, U.macrocarpa, M.citrifolia, C.limon, L.japonica, E.bicyclis, S.deserta, V.labrusca. Most found active compound with antiplatelet activity are flavonoids, fraction quercetin. Mechanism of action on COX-1, AA, TXA2, P13K pathways, increased cAMP, VASP stimulation. Extraction methods by maceration, reflux, soxhlet, sonication, juice, distillation. Isolation methods using CC, HPLC, TLC, NMR
Antibacterial activity of extract sangkareho leaves (Callicarpa longifolia LAM.) on Salmonella typhi and Staphylococcus epidermidis Silvani Permatasari; Ervi Audina Munthe; Muntir Guru Singa; Elsa Trinovita; Ratna Widayati; Natalia Sri Martani; Anna Marthea Veronica
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art7

Abstract

Background: The most commonly found disease-causing microorganisms are the Salmonella typhi and Staphylococcus epidermidis bacteria. S.typhi is a gram-negative bacterium that causes typhoid fever, and S.epidermidis is a gram-positive bacterium that attacks mucous membranes and human skin. Sangkareho (Callicarpa longifolia Lam.) is one of the indigenous herbal plants of Central Kalimantan, which is empirically used as a wound medicine, diarrhea, diabetic, anti-inflammatory, and can be an antibacterial agent.Objective: This study used six groups are concentrations of 10%, 25%, 50%, and 100%, Chloramphenicol as a positive control, and dimethyl sulfoxide (DMSO) as a negative control. Methods: The method used for this test is the well diffusion method. In Nutrient Agar (NA) media, holes were made to insert 40 μl of each extract concentration, positive and negative control with four repetitions, then incubated for 18-24 hours at 37ºC. Data analysis using the One Way Anova test.Results: The research findings showed that ethanol extract of sangkareho leaves with all concentrations had an inhibitory effect against both bacteria tested.Conclusion: The ethanol extract of sangkareho leaves at the concentration of 10% was found to be the optimum and at the concentration of 100% was the maximum effectiveness for inhibiting S. typhi and S. epidermidis.