Article Per Year (5 Year)
p-Index From 2019 - 2024
0.23
P-Index
This Author published in this journals
All Journal Microbiology Indonesia
SUCI FARADILLA
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Polyoxygenated Diterpene Produced by The Indonesian Marine Sponge Callyspongiasp. as an Inhibitor of the Human Pancreatic Cancer Cells VIQQI KURNIANDA; SUCI FARADILLA; SOFYATUDDIN KARINA; SRI AGUSTINA; MARIA ULFAH; CHITRA OCTAVINA; FARAH SYAHLIZA; MUHAMMAD RIZKI RAMADHAN; SYAHRUL PURNAWAN; MUSRI MUSMAN
Microbiology Indonesia Vol. 13 No. 2 (2019): June 2019
Publisher : Indonesian Society for microbiology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (986.522 KB) | DOI: 10.5454/mi.13.2.5

Abstract

The bioactive compound from the Indonesian Marine SpongeCallyspongia sp.isolated based on bioassay-guided separation with several steps of chromatography has been done. There are 4 major compound known as isocopalane diterpene derivatives together with a plausible new compound, isocopalanol, a polyoxygenated isocopalane diterpene. Isocopalanol has molecular weight [M+H]+ 412.576 m/z indicate that the compound has molecular formula C24H44O5 determined by LCMS-ESI. This compound has bioactivity IC50 = 0.1 μg / mL against human pancreatic cancer cell. 
Co-Authors Chitra Octavina FARAH SYAHLIZA MARIA ULFAH Muhammad Rizki Ramadhan Musri Musman Sofyatuddin Karina Sri Agustina Syahrul Purnawan Viqqi Kurnianda