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All Journal Pharmacon Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Medical Sains : Jurnal Ilmiah Kefarmasian
Arifin Santoso
Universitas Islam Sultan Agung
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Jurnal Farmasi Sains dan Praktis

 1 
PENGARUH KONSENTRASI AMILUM UBI JALAR PUTIH (Ipomoea batatas L) SEBAGAI BAHAN PENGIKAT SECARA GRANULASI BASAH TERHADAP SIFAT FISIK GRANUL DAN TABLET SERTA PROFIL DISOLUSI TABLET PARACETAMOL Indriyati Hadi Sulistyaningrum; Arifin Santoso; Abdur Rosyd; Anis Rosita
Jurnal Farmasi Sains dan Praktis Vol 4 No 1 (2018)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v4i1.2584

Abstract

Hampir 90% bahan baku obat, baik zat aktif maupun bahan tambahan (eksipien) di Indonesia didapatkan melalui impor dari luar negeri, padahal sumber daya Indonesia dapat dikembangkan. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan bahan pengikat amilum ubi jalar (Ipomoea batatasL) dalam berbagai konsentrasi terhadap sifat fisik granul, tablet dan profil disolusi tablet paracetamol. Pada penelitian ini menggunakan penelitian eksperimental dengan design posttest only control group yaitu menggunakan lima formula amilum ubi jalar putih dan tablet paracetamol merk dagang sebagai kontrol positif. Formula yang digunakan yaitu konsentrasi 5%, 10%, 15%, 20%, dan 25%. Kemudian dilakukan uji granulasi, keseragaman bobot, kekerasan, kerapuhan, disintegrasi dan disolusi. Hasil penelitian menunjukkan bahwa tablet paracetamol dengan bahan pengikat amilum ubi jalar putih yang dibuat memenuhi persyaratan fisik sesuai standar Farmakope Indonesia. Tablet paracetamol yang dihasilkan berwarna putih, memenuhi persyaratan ketika dilakukan pemeriksaan fisik meliputiuji granulasi, keseragaman bobot, kerapuhan, namun pada uji kekerasan didapatkan formula yang memenuhi persyaratan farmakope yaitu pada formula 1 (5%), uji waktu hancur dan disolusi formulasi yang memenuhi syarat adalah formula 1,2,3 (5%,10% dan 15%). Berdasarkan uji analasis Anova dan Kruskal wallis didapatkan terjadinya perbedaan signifikan antar kelompok perlakuan pada uji pengetapan granul, keseragaman bobot, kekerasan, kerapuhan, disintegrasi dan disolusi (p<0,05), kemudian dilanjutkan uji Mann-Whitney dan tidak terjadi perbedaan signifikan antar kelompok pada uji waktu alir dan sudut diam (p>0,05). Kesimpulan dalam penelitian ini adalah konsentrasi amilum ubi jalar putih (Ipomoea batatasL) terhadap sifat fisik granul, tablet dan profil disolusi tablet paracetamol dengan konsentrasi 5% sampai 10%.
COMPARATIVE OF REAL COST AGAINST THE PRICE OF INA-CBG’S BREAST CANCER AND ITS AFFECTING FACTORS IN JKN PROGRAM ERA Arifin Santoso; Indriyati Hadi Sulistyaningrum; Abdur Rosyid; Erwin Budi Cahyono; Ken Wirastuti; Bagus Riyanto
Jurnal Farmasi Sains dan Praktis Vol 6 No 1 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i1.2963

Abstract

This study aims to determine differences in real cost and INA CBG's rate and to find out the factors that influence the difference between the real cost and INA CBG's rate in patient with breast cancer in JKN Era at Sultan Agung Islamic Hospital between January 2017 and October 2017. This type of research is a non-experimental (observational) study, data taken retrospectively from hospital financial data and medical records of patients. Data analysis using Mann-Whitney is used to determine the suitability of real costs with INA CBG rates. and the Kruskal-Wallis test is used to find out what factors affect real costs. There was difference between the real cost and the INA CBG's rate for class 1 of Rp (-9,861,600), class 2 of Rp (30,643,000), and class 3 of Rp (146,724,100). The factors that influence the real costs were nursing class (p = 0.014) and Length of stay (p = 0.000). The conclusion of this study is that there is a difference between the real cost in patient with breast cancer in JKN Era at Sultan Agung Islamic Hospital between January 2017 and October 2017.
Analysis Of Drug Indicator At The Procurement Stage In The National Health Insurance Era: A study in Advance Health Facility Indriyati Hadi Sulistyaningrum; Arifin Santoso; Sri Intan Lestari; Kusuma Arbianti
Jurnal Farmasi Sains dan Praktis Vol 5 No 2 (2019)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v5i2.2964

Abstract

Drug procurement is part of an important hospital management to support the availability of the pharmaceutical logistic in hospital to provide good services for the patients. ineffective procurement can result in not achieving the availability of each drug in the amount which are in accordance with the price and budgeting. This research was conducted to obtain an overview of drug management at the procurement stage in Sultan Agung Islamic Hospital (RSIA SA) for the 2017 – 2018 period. Descriptive Observational research methods were used to collect the qualitative and quantitative data. Qualitative data were obtained through interview, and the quantitative data were collected from the document observation provided in Pharmaceutical installation Sultan Agung Islamic Hospital (IFRSISA). The result showed the percentage of the allocation of drug procurement funds in 2017 was 47,6%, and in 2018 it was 37,1%, the frequency of procurement of each drug type was < 76% at 12 times / year, the frequency of delayed payment by the hospital based on the time agreed was 100%. The conclusion of this study shows that the indicator of drug procurement in IFRSISA categorized as good because it is in line with the quality of drug procurement indicators.
Co-Authors Abdur Rosyd Abdur Rosyid Anis Rosita Arina Kautsari Bagus Riyanto Chilmia Nurul Fatiha Dian Mila Fatmawati Erwin Budi Cahyono Fadya Rahma Putri Fildza Huwaina Fathnin Indriyati Hadi Sulistiyaningrum Indriyati Hadi Sulistyaningrum Ken Wirastuti Kusuma Arbianti Meki Pranata Nida Fauziyah Azzahroh Rina Dwi Lestari Sri Intan Lestari