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All Journal MEDIA MEDIKA INDONESIANA Indonesian Journal of Cancer Sari Pediatri Paediatrica Indonesiana ACI (Acta Cardiologia Indonesiana) Indonesian Journal of Cancer
Indah Kartika Murni
Universitas Gadjah Mada
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Indonesian Journal of Cancer

 1 
Profil Jantung Pasien Akut Limfoblastik Leukemia Anak yang Mendapatkan Terapi Anthracycline DAVID VICTORY WA’U; SRI MULATSIH; INDAH KARTIKA MURNI
Indonesian Journal of Cancer Vol 11, No 1 (2017): Jan-Mar
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.452 KB) | DOI: 10.33371/ijoc.v11i1.496

Abstract

ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common malignancy in children under fifteen years of age. Advanced cancer therapy with anthracycline has increased survival rate but also chronic health problem and the most iscardiovascular. This study aims to describe cardiac events of ALL patients who received anthracyline during chemotherapy. We conducted a cross sectional study of childhood ALL who were hospitalized at DR Sardjito hospital between April and June 2016. Electrocardiography (ECG) and echocardiography were performed. Results of this study shows childhood ALL who received anthracycline may suffer from cardiotoxicity. Cardiac events can be found in all stage of chemotherapy.ABSTRAKLeukemia limfoblastik akut (LLA) adalah keganasan yang paling banyak dialami anak di bawah usia 15 tahun. Kemajuan pengobatan kanker dengan anthracycline telah meningkatkan angka kesintasan penderita LLA dan masalah kesehatan kronik, terutama penyakit kardiovaskuler. Penelitian ini bertujuan untuk mengetahui kelainan jantung pada pasien LLA yang mendapatkan kemoterapi anthracyline. Penelitian dilakukan secara potong lintang dengan subjek anak penderita LLA yang dirawat di rumah sakit Dr. Sardjito antara April–Juni 2016. Pasien menjalani pemeriksaan elektrokardiografi (EKG) dan echocardiography. Penelitian ini menyimpulkan bahwa anak penderita ALL yang mendapatkan anthracycline dapat mengalami kardiotoksisitas. Kelainan jantung dapat ditemukan pada semua tahap kemoterapi.
Co-Authors Agung Triono Amalia Setyati Amalia Setyati Artha Christin Yulianti Bibit Murdiyanti Carolina Kurniawan DAVID VICTORY WA’U Desy Rusmawatiningtyas Dian C Sulistyoningrum Dwikisworo Setyowireni Eggi Arguni Emmanuel Mareffcita Siagian Ida Safitri Madarina Julia Meily Elven Nora Nadia Qoriah Firdausy Nadya Arafuri Noormanto Noormanto Noormanto Noormanto Nurnaningsih Nurnaningsih Rina Susilowati Roni Naning Sasmito Nugroho Sasmito Nugroho Sri Mulatsih Sri Mulatsih WA’U, DAVID VICTORY Weny Inrianto Winda Paramitha Yudha Fadhol Arafah Yusuf Yusuf