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Pengaruh pemberian ekstrak tinta cumi (squid ink) terhadap aterosklerosis Nasution, Fajar M.; Mardia, Rina S.; Azri, Ayu; Hutabarat, Rido R.; Izza, Fadhila Al.; Asfur, Robitah
e-Biomedik Vol 5, No 2 (2017): eBiomedik
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ebm.v5i2.16612

Abstract

Abstract: Squid ink consists of DHI, DHICA, and 2-carboxyl indole that improve lipid profile and remove foam cells in blood vessel walls. This study was aimed to analyze the effect of squid ink on atherosclerosis-induced Wistar rats. This was an experimental study. We used randomized controlled trial with pre-post test design for lipid profile assessment and randomized post-test only control design for blood vessel evaluation (foam cells in layers of coronary artery). Samples were 27 Wistar rats, divided into three groups; all were atherosclerosis-induced with initial injection of 0.006mg iv adrenalin on day 1, followed by standard diet and egg yolk until day 30. Squid ink extract was given to group P1 and P2 on days 15-30 in different doses, but not to control group. Data were analyzed by using Saphiro-Wilk test and paired t-test. The results showed that P2 group had decreased means of total cholesterol (-33.62 mg/dl), triglyceride (-28.00 mg/dl), and LDL cholesterol (-28.16 mg/dl), but an increased mean of HDL cholesterol (11.60 mg/dl). There were decreased numbers of foam cells in the layers of coronary arteries of P1 and P2 group compared to the control group. Conclusion: Squid ink extract could lower total cholesterol, triglyceride, and LDL cholesterol levels, and increase HDL cholesterol level. Moreover, it could remove foam cells from the layers of coronary arteries.Keywords: squid ink, atherosclerosis, lipid profile, foam cells Asbtrak: Tinta cumi memiliki kandungan DHI, DHICA, dan 2-carboxyl indole yang dapat memperbaiki profil lipid dan mengurangi sel busa pembuluh darah. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak tinta cumi terhadap tikus yang diinduksi aterosklerosis. Jenis penelitian ialah eksperimental dengan randomized controlled with pre-post test design untuk penilaian profil lipid dan post test only design untuk penilaian pembuluh darah (sel busa dalam dinding arteri koronaria). Sampel terdiri dari 27 tikus Wistar jantan, dibagi secara random menjadi tiga kelompok; kesemuanya diberi induksi aterosklerosis dengan injeksi inisial adrenalin 0,006 mg iv pada hari ke-1, dilanjutkan diet standar dan diet kuning telur sampai hari ke-30. Tikus kelompok kontrol tidak diberikan ekstrak tinta cumi; tikus kelompok perlakuan 1 dan perlakuan 2 diberikan tambahan ekstrak tinta cumi pada hari ke 16 sampai hari ke 30 dengan dosis yang berbeda. Analisis data dengan uji Saphiro-Wilk dan uji paired t-test. Hasil penelitian memperlihatkan penurunan rerata setelah perlakuan pada kelompok P2 ialah kolesterol total (-33,62 mg/dl), trigliserida (-28,00 mg/dl), dan kolesterol LDL (-28,16 mg/dl), serta peningkatan rerata kolesterol HDL (11,60 mg/dl). Terdapat penurunan jumlah sel busa kelompok perlakuan P1 dan P2 dibandingkan kelompok kontrol. Simpulan: Pemberian ekstrak tinta cumi menurunkan kadar kolesterol total, trigliserida dan kolesterol LDL, meningkatkan kadar kolesterol HDL, serta menurunkan jumlah sel busa dalam dinding arteri koronaria.Kata kunci: tinta cumi, aterosklerosis, profil lipid, sel busa
PEMBINAAN USAHA KESEHATAN SEKOLAH (UKS) DI SEKOLAH - SEKOLAH MUHAMMADIYAH KOTA MEDAN Nurfadly, Nurfadly; Asfur, Robitah; Damayanty, Amelia Eka
JURNAL PRODIKMAS Hasil Pengabdian Kepada Masyarakat Vol 4, No 2 (2019)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Muhammadiyah merupakan suatu persyarikatan yang sangat memperhatikan kesejahteraan umat dan mengembangkan amal usaha di banyak bidang diantaranya bidang kesehatan dan pendidikan. Muhammadiyah memiliki amal usaha di bidang pendidikan  hampir di seluruh wilayah Indonesia tersebar secara merata. Di kota Medan terdapat  lebih kurang 50 sekolah dasar Muhammadiyah dan memiliki hampir 15.000  murid.  Sekolah sebagai tempat belajar, harus memiliki lingkungan bersih dan sehat, yang mendukung berlangsungnya proses belajar dan mengajar yang baik, serta  diharapkan mampu membentuk siswa yang memiliki derajat kesehatan yang lebih baik untuk mendukung pencapaian tujuan pendidikan.  Untuk  mencapai tujuan tersebut maka setiap sekolah dianjurkan mempunyai Usaha Kesehatan Sekolah (UKS). Masalah yang dihadapi selama ini adalah sebagian besar sekolah Muhammadiyah belum mempunyai UKS, padahal UKS sangat diperlukan untuk terciptanya sekolah sehat.   Sehingga dilaksanakanlah kegiatan PKPM yang bertujuan untuk membina UKS di sekolah dasar-sekolah dasar Muhammadiyah di Kota Medan.  Kegiatan dilaksanakan di gedung pertemuan Madrasah Tsanawiyah Aisyiah pada pertengahan April dan dihadiri oleh 10 kepala sekolah dasar Muhammadiyah atau perwakilannya.
PENGEMBANGAN METODE BELAJAR DAN MELATIH SKILL MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH DI KLINIK AISYIYAH DI KOTA MEDAN Asfur, Robitah; Yenita, Yenita; Nurfadly, Nurfadly
JURNAL PRODIKMAS Hasil Pengabdian Kepada Masyarakat Vol 4, No 1 (2019)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Pengembangan setiap Fakultas Kedokteran memang merupakan target pasar dalam persaingan untuk merekrut minat setiap calon mahasiswa, mengingat Muhammadiyah besar dalam amal usahanya baik di bidang pendidikan dan bidang kesehatan, Fakultas Kedokteran Universitas Muhammadiyah Sumatera utara memiliki keunggulan besar karena amal usaha dibidang kesehatan berupa rumah sakit muhammadiyah dan klinik aisyiyah di seluruh daerah dan cabang. Tujuan program kegiatan Ipteks bagi Inovasi Kreativitas Kampus Fakultas Kedokteran Universitas Muhammadiyah Sumatera Utara adalah Inovasi metode belajar dan melatih skill mahasiswa sebelum menuju praktek di rumah sakit (Koas). Beberapa program yang akan dikembangkan adalah melatih kemampuan belajar mahasiswa, mengasah skill seperti partus normal, immunisasi, edukasi dan mempelajari program BPJS. Program lain yang diberikan oleh klinik Aisyiyah adalah memberi penyuluhan kesehatan di pengajian ? pengajian ibu ? ibu Aisyiyah, edukasi sekolah untuk mengaktifkan UKS yang ada di sekolah dan belajar Home visite yang diberikan klinik Aisyiyah kepada warga yang tidak dapat datang berobat langsung ke klinik Aisyiyah sehingga mahasiswa mulai terbiasa dengan kegiatan sebagai dokter yang bekerja di faske pertama. Rencana ke depan yang ingin dicapai FK UMSU adalah menjadikan FK UMSU lebih besar lagi, dan menjadi pusat unggulan dan terpercaya dalam dunia pendidikan dan dunia kesehatan yang memiliki nilai Muhammadiyah dan Aisyiyah setiap lulusan FK.UMSU.
PENGARUH SUPLEMEN KALSIUM TERHADAP KADAR KALSIUM DARAH DAN BONE MINERAL DENSITY ( BMD ) PADA WANITA PENGGUNA KONTRASEPSI DEPO MEDROKSI PROGESTERON ASETAT ( DMPA ) Robitah Asfur; M. Thamrin Tanjung; Mutiara Indah Sari
JURNAL ILMIAH MAKSITEK Vol 3 No 4 (2018): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Nowadays osteoporosis has became a global issue since the prevalence increased with lifestyle. Osteoporosis is a metabolic bone disease that can be seen by reduction in bone mass, than bone microarchitecture and the increment of bone fragility, so there will be a greater risk of fracture. Osteoporosis accurs with increasing aging population. One of the side effects of contraceptive depot medroksi progesterone acetate is osteoporosis, the use of contraceptive depot medroksi progesterone acetate which might inhibit the production of ovarian estradiol, theoretically increasing the risk of osteopenia and osteoporosis after menopause. Calcium is olso a mineral most often given to treat osteoporosis because of the effects of calcium on bone is directly related to bone formation. The research objective was to determine the effect of calcium supplementation on blood calcium levels and bone mineral dencity (BMD) in women on contraceptive depot medroksi progesterone acetate.This study is an experimental study with pre and post test design only with a simple randomization. Subjects were reproductive women around 21 years – 44 years old as many as 30 persons that were devided into 3 groups : normal group, osteopenia and osteoporosis. BMD and blood calcium of each group was examined and measured after given calcium supplement in 30 days, 60 to 90 days.The results showed that the given sample with calcium supplements for 30 days, 60 days and 90 days showed a significant increase in blood calcium levels and BMD ( p ≤ 0,05 ).
SIKAP DAN PERILAKU TENTANG KESEHATAN MATA PADA ANAK PANTI ASUHAN MUHAMMADIYAH DI KOTA MEDAN HADI NURVAN; ZALDI .; LASZUARNI .; ROBITAH ASFUR
JURNAL ILMIAH SIMANTEK Vol 3 No 3 (2019): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Eyes are organs that is found in every human being. This organ has a very important function in every human. The problems of the health of eyes are still very important for the developed countries and also developing countries especially in Indonesia particularly. Refraction disorders are usually caused by the presence of a factor in the habit of reading too closely so that cause fatigue on eyes (astenopia) and excessive light radiation is received, which are light radiation of computer and television. School environment is being one of the triggers decline sharpness of vision in children, such as reading the existing writings on the board with a distance too far without being supported by lighting adequate classroom, the children read a book at a distance that is too close, and infrastructure of the school that are not ergonomic when teaching and learning process. The purpose of this research is to know the description of attitudes and behaviours towards healthy eyes in children orphanage of Muhammadiyah in Medan. Methods: The type of research used in this study is cross sectional research with quantitative approach. The sample of this research is as much as fifty childrens of junior level and vocational school level Muhammadiyah in an orphanage in the city of Medan. Results: Respondents with normal visus that have good attitude and behavior are two subjects, moderate with twentysix subjects, and less with two subjects, while the respondents with abnormal visus that have good attitude and behavior are four subjects, moderate with eleven subjects, and less with five subjects. Conclusion: The overview of attitude and behavior toward eye health of Muhammadiyah orphanage in Medan City are generally in the moderate category.
PENGARUH OLAHRAGA INTENSITAS SEDANG TERHADAP KUALITAS TIDUR LANSIA DI PIMPINAN RANTING AISYIYAH CABANG MELATI PADA TAHUN 2018 NABILA HANA SYAQILA; GUSBAKTI RUSIP; AMELIA EKA DAMAYANTI; ROBITAH ASFUR
JURNAL ILMIAH SIMANTEK Vol 4 No 4 (2020): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Increasing the elderly population globally is a challenge and also an opportunity in all countries. This increase will have apositive impact if the elderly are in a healthy, productive and independent situation. WHO (World Health Organization) statedthat the elderly population in Indonesia in the next two years, in 2020 will reach more than 28 million people, placingIndonesia as the country with the largest elderly population in the world. Healthy elderly refers to the active concept of agingstated by WHO. According to WHO, active aging is the process of developing and maintaining the ability of the elderlyincluding basic needs for the elderly, social interaction and play a role in society, contribute and be able to build and maintainsocial relations. It can be said that a healthy elderly person is a person who has a good quality of life. One indicator of goodquality of life is the quality of sleep. Based on the background the researcher have described above, researcher is interestedknowing the effect of moderate intensity exercise on the quality of elderly sleep at the Pimpinan Ranting Aisyiyah CabangMelati, Medan 2018. This study aims to know the effect of moderate intensity exercise towards quality of sleep in elderly atthe Pimpinan Ranting Aisyiyah Cabang Melati, Medan 2018. This study is experimental using quasi experiment pre-test posttestcontrol group design. Data are collected by PSQI quesionairre. The results of the study showed that there was an effectof moderate intensity exercise towards quality of sleep in elderly at Pimpinan Ranting Aisyiyah Cabang Melati, Medan.Using Wilcoxon Test obtained the p value = 0.001 in the group of respondents who were given the intervention. There is aneffect of moderate intensity exercise towards quality of sleep in elderly at Pimpinan Ranting Aisyiyah Cabang Melati, Medan.
GAMBARAN KARAKTERISTIK ASUPAN NUTRISI TERHADAP KEJADIAN STUNTING DI DESA SECANGGANG KABUPATEN LANGKAT HANY SARAH PILIANG; ROBITAH ASFUR
JURNAL ILMIAH SIMANTEK Vol 5 No 2 (2021): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Stunting is a condition of failure to thrive in children under the age of five years old due to chronic malnutrition, whichtherefore then results in the child being too short for their age. Stunting is measured by height or height more than minus twostandard deviations from the median child growth according to WHO. Langkat, North Sumatra is the area that has the mostcases of stunting. This study aims to look at the characteristics of nutritional intake of children with stunting in the Village ofSecanggang, Langkat Regency. This study uses analytic descriptive with a cross sectional research design that meets theinclusion and exclusion criteria by purposive sampling. The number of samples in this study were 27 stunting toddlers basedon the data provided by the Public Health Centre and the 2013 Basic Health Research. With the use of a validatedquestionnaire that were then given to the parents of children with stunting. Stunting children were given high proportions ofnutritional intake, including those who receive MPASI after 6 months 26 people (96,3%), born within the ideal month 25people (92,6%), consuming fruits 24 people (88,9%) and mothers taking vitamins during pregnancy 23 people (85,2%).Nutritional intake factors that is associated with the incidence of stunting are birth weight <2500.
HUBUNGAN TINGKAT PENGETAHUAN MASYARAKAT TERHADAP KEJADIAN STUNTING DI DESA SECANGGANG KABUPATEN LANGKAT TAUFIQ ASRI MUNANDAR; ROBITAH ASFUR
JURNAL ILMIAH SIMANTEK Vol 5 No 2 (2021): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Stunting is one of the most significant inhibiting factors for development and globally affects around 162 million childrenunder 5 years of age, defined as less than -2 standard deviations (SD) based on child growth standards according to theWorld Health Organization (WHO). National Stunting prevalence in 2013 was (37.2%), which means an increase comparedto 2010 (35.6%) and 2007 (36.8%). One important factor influencing nutritional status in infants is the mother's knowledgeabout nutrition in infants. Lack of mother's knowledge about the diversity of materials and diversity of food types will disruptthe process of growth and development of infants, especially brain development, therefore mothers need to provide nutritiousfood intake to their children. This study aims to relate the level of community knowledge to the incidence of stunting inSecanggang Village, Langkat Regency. This research uses a descriptive-analytic method with a cross-sectional design. Datawere processed using the SPSS Chi-Square test. The results showed that the relationship between the level of communityknowledge and the incidence of stunting in Secanggang Village, Langkat Regency showed a p-value of 0.004 (p <0.05).There is a significant correlation between the level of community knowledge on the incidence of stunting in SecanggangVillage, Langkat Regency.
PENGARUH PEMBERIAN SUSU KEDELAI ( GLICINE MAX L. MERR ) PADA WANITA MENOPAUSE YANG BERESIKO OSTEOPOROSIS DI PENGAJIAN IBU – IBU AISYIYAH RANTING MELATI MEDAN ROBITAH ASFUR; AMELIA EKA DAMAYANTY
JURNAL ILMIAH SIMANTEK Vol 5 No 2 (2021): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Menopause causes a significant decrease in estrogen levels that affect various conditions in the body, one of which ischanges in bone that occur due to low estrogen. Osteoporosis is a progressive chronic bone disorder caused by reducedbone mass and changes in structure in bone microarchitecture tissue that increases the risk of fracture and can reducequality of life, especially in menopausal women. Soy milk contains phytoestrogens so that can relieve menopausalsymptoms. To prove whether there is an influence of soy milk on bone mineral dencity in menopausal women who are at riskof osteoporosis. Experimental study with pre and post test group design. Sampling technique with simple randomization.The sample of 30 postmenopausal women who were given soy milk as much as 250 ml / day for 3 months. Before and afterthe intervention Bone Mineral Dencity (BMD) examination was performed with osteopeni and osteoporosis results.The mean value of BMD before intervention was -2.5833 The mean value of BMD after the intervention was-2.2267 Thedifference in BMD before and after the intervention with p = 0.001. There is an effect of 250 ml / day soy milk on BMD inmenopausal women.
PENGARUH PEMBERIAN MADU TERHADAP FUNGSI GINJAL (UREUM DAN KREATININ) TIKUS PUTIH (Rattus norvegicus L.) JANTAN GALUR WISTAR YANG DI INDUKSI TUAK. ROBITAH ASFUR; GUNAWAN SADEWO
JURNAL ILMIAH KOHESI Vol 3 No 2 (2019): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Introduction: Honey is one of the human food ingredient produced by bees. Honey is a food that is special and has a high nutritional value. Honey contains many minerals, flavonoids and phenolic acids substance that serves as an antioxidant agent that can prevent kidney damage. A drink or a traditional medicine belonging to the liquor if it contains alcohol> 1%. Tuak is a typical alcoholic beverage from batak, made from coconut or palm stems taken the water and then mixed with raru. Objective: This research is to know the effectiveness of honey in renal function (urea and creatinine) white rat (Rattus norvegicus L.) Wistar male in induction palm wine. Methodology: The research used True Experiment method with "pretest-posttest with control group design" design Result: The results show that the P value for urea number is <0.05, and the P value for creatinine levels also showing <0.05. Conclusion: there is an effect of honey in renal function (urea and creatinine) white rat (Rattus norvegicus L.) Wistar male in induction palm wine (Tuak ).