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All Journal International Journal of Public Health Science (IJPHS) Indonesian Journal of Tropical and Infectious Disease Biomolecular and Health Science Journal International Journal of Nasopharyngeal Carcinoma

Firas Farisi Alkaff

Department Of Pharmacology And Therapy, Faculty Of Medicine Universitas Airlangga, Surabaya, Indonesia

Author-ID : 3402022

Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Published : 7 Documents Claim Missing Document

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Articles

Convalescent Plasma Therapy: The Early Use in Moderate to Severe COVID-19 Patients in Hospitals with Limited Resources Bagus Aulia Mahdi; Satriyo Dwi Suryantoro; Pradana Zaky Romadhon; Choirina Windradi; Krisnina Nurul Widiyastuti; Dwiki Novendrianto; Etha Dini Widiasi; Esthiningrum Dewi Agustin; Sarah Firdausa; Firas Farisi Alkaff
Indonesian Journal of Tropical and Infectious Disease Vol. 9 No. 3 (2021)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v9i3.29113

COVID-19 cases in Indonesia in the period of June-July 2021 showed a catastrophic spike. During this period, a recently discovered variant, the delta variant, appeared to be one of the sources of COVID-19 infection. Treatment modalities are limited due to reduced stock of drugs. A case of a 63-year-old man has been reported, with a history of having been vaccinated with two doses of Sinovac, experiencing moderate-to-severe symptoms of COVID-19 infection then given convalescent plasma therapy since his initial admission to the hospital. Three days after being given convalescent plasma therapy, the improvement was noticeable. Shortness of breath, cough, fever, and weakness were less complained. On the seventh day the patient fully recovered and got discharged. Convalescent plasma therapy was e ective in early stage and was able to improve outcomes. Indonesia needs sucient stocks of convalescent plasma as a therapy to overcome the limitations of medicines.

Role of Bariatric Surgery for Reducing Glycated Hemoglobin (Hba1c) in Type 2 Diabetes Mellitus Compared to Current Medicaments Therapy Firas Farisi Alkaff; Ricardo Adrian Nugraha; Michael Jonatan; Sulistia wati
Biomolecular and Health Science Journal Vol. 1 No. 1 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Introduction: Type II is the most common type of Diabetes Mellitus, and one of the most common non-communicable diseases globally. In Indonesia, diabetes contributes to 6% of total deaths. Current medicaments therapy available can only control the disease, not to cure it. Recently, there has been new treatment that has been recommended into standard care for type II Diabetes Mellitus. It was in September 2015 at the second Diabetes Surgery Summit that the introduction of bariatric surgery has been put into standard care for type II Diabetes Mellitus.Objective: To draw a comparison of the effectiveness between bariatric surgery and current medicaments therapy in reducing HbA1c to achieve remission.Methods: Literature study was conducted to identify relevant literature showing comparison study between bariatric surgery and medicaments therapy, and comparison study between types of bariatric surgery. 16 Studies are included in this article from 230 studies found.Results: HbA1c remission in bariatric surgery is significantly higher than medicaments therapy in all studies, ranging from 66.7% vs 0% to 57.1% vs 9.5% during 6-24 months after therapy. Between all types of bariatric surgery, most of the studies shows that Roux-en-Y Gastric Bypass achieves HbA1c remission higher than other types of surgery.Conclusion: Bariatric surgery is better than current medicaments therapy in achieving HbA1c remission.

Hematemesis on Hepatic Cirrhosis Patients in Area with Limited Facilities Yudha Klahan; Firas Farisi Alkaff
Biomolecular and Health Science Journal Vol. 1 No. 1 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Esophageal variceal haemorrhage is one of the more dangerous complications of hepatic cirrhosis. Initial treatment can determine patient mortality and morbidity. But not all hospitals have adequate facilities and medicines to handle it. The 53-year-old woman came with a diagnosis of ascites and hematemesis. At the initial examination found hypotension. Laboratory results show anemia, thrombocytopenia, and leukocytosis. The next morning the patient's condition worsened and was transferred to ICU. During the ICU patients receive 10 lpm oxygen support, cefobactam, pantoprazole, PRC transfusion, and dopamine. Patients begin conscious on the 5th day of treatment. Then the patient started getting diuretics on day 6 and propranolol on day 9. On day 13 the patient's condition improved and the patient was discharged for outpatient treatment. Limitations of the endoscopic tool cause not every hospital in Indonesia can perform emergency endoscopy for therapy. However, with rapid and appropriate pharmacological therapy, patients can be helped not to fall into mortality and prevent recurrent bleeding.

Depression Level Difference Between Gifted and Non-gifted Medical Students Firas Farisi Alkaff; Adila Taufik Syamlan; Michael Jonatan; Ricardo Adrian Nugraha; Tan Nicko Octora; Azimatul Karimah
Biomolecular and Health Science Journal Vol. 1 No. 2 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Introduction: Depression is a common mental health conditions in the world. Compare to general population, the prevalence of depression in medical students are higher. There are several risk factors that might contribute to the higher rate of depression in medical students, including being a gifted student. However, no study has been published regarding the depression of the gifted medical students until now.Aim: To find out the difference in the level of depression between gifted and non-gifted medical students. Methods: This study was a descriptive cross-sectional study, conducted from October to December 2016. Subjects were third year medical students from Faculty of Medicine Universitas Airlangga. There were 2 groups in this study. Samples from gifted students group was obtained using total sampling method, while number of samples from non-gifted students group was equated with gifted students group. Depression was measured using Beck Depression Inventory (BDI). Mann-Whitney U test was used for statistical analysis. Results: 34 students, 17 students in the gifted students group and 17 students in the non-gifted students group, were included in this study. Based on the BDI score results category, 2 students from the gifted students group and 1 student from non-gifted students group were in the mild category, and 1 student from the gifted students group was in the borderline category. The highest BDI score in gifted students group were 14, while in non- gifted students group were 17. There was no significant difference of the BDI score and BDI category between groups (p = 0.154; 0.951, respectively).Conclusion: There was no significant difference of depression level between gifted and non-gifted medical students.

The Unusual Presentation of Acute Pericarditis Mimicking Acute Coronary Syndrome Ryan Enast Intan; Tan Nicko Octora; Firas Farisi Alkaff; Dimas Rio Balti
Biomolecular and Health Science Journal Vol. 2 No. 2 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Pericarditis is a common disorder that might present in various settings, including primary-care and emergency department. However, the clinical features in some cases did not match with the written theory, which could lead to a misdiagnosis. A 46-year-old man presented to the emergency room with progressive tightness chest pain, epigastric pain, nausea, and vomiting in the past 2 days. Based on the clinical, electrocardiograph (ECG), and laboratory evaluation, the patient was diagnosed with unstable angina pectoris and treated accordingly but did not showed an improvement. Clinical re-examination and echocardiography evaluation showed a pathognomonic finding of pericarditis feature. Combination therapy of colchicine and ibuprofen was given for 3 weeks. One-month follow-up evaluation showed normal ECG and echocardiography result without any remaining symptoms. Acute pericarditis does not always show typical finding. Therefore, clinician must always aware with other differential diagnosis of chest pain and ECG variation of acute pericarditis.

Are Indonesian new pictorial health warnings more effective than the old ones? Jovian Philip Swatan; Firas Farisi Alkaff; William Putera Sukmajaya; Sulistiawati Sulistiawati; Azimatul Karimah
International Journal of Public Health Science (IJPHS) Vol 11, No 3: September 2022
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v11i3.21543

Smoking remains as a nation-wide health problem in Indonesia. Several measures had been conducted to motivate smoking cessation, among those is the use of pictorial health warnings (PHWs). PHWs have been implemented since 2014, and some of the pictures were revised in 2018. However, there was no evaluation regarding the effectivity to this date. This study compared the effectivity of the old and new versions of PHWs in promoting smoking cessation. This was a cross-sectional study conducted in one of the sub-districts in East Java, Indonesia, in February 2020. Study population were local villagers aged at least 18 years who visited the sub-district’s primary healthcare during the study period. Consecutive sampling was used as the sampling method. Respondents were interviewed using a pre-determined questionnaire. The old and new versions of PHWs were printed and showed to the respondent during the interview. Comparison between groups was analyzed using McNemar test. A total of 103 respondents participated in this study. More respondents agreed that the old version of PHWs was considered more effective to motivate smoking cessation as compared to the newer version (71.84% vs 64.08%), although the significance was marginal (p=0.077). Our study showed that both versions of PHWs were considered effective to promote smoking cessation. However, more respondents agreed that the old version of PHWs were more effective than the new PHWs. We recommend policymaker to conduct a field study to test the effectivity of the proposed PHWs before revising the legal regulation in the future.

RADIOTHERAPY EFFECT ON COMPLETE BLOOD COUNT PARAMETER IN PATIENTS WITH NASOPHARYNGEAL CARCINOMA Achmad Chusnu Romdhoni; Firas Farisi Alkaff; Mega Kahdina; Melinda Masturina; Ristra Ramadhani
INTERNATIONAL JOURNAL OF NASOPHARYNGEAL CARCINOMA Vol. 2 No. 01 (2020): International Journal of Nasopharyngeal Carcinoma
Publisher : TALENTA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijnpc.v2i01.3505

Introduction: Nasopharyngeal carcinoma (NPC) is the most common malignant tumor of the nasopharynx. Radiotherapy is a therapy of choice for NPC that has been recognized for a long time and used in various centers of the world. However, radiotherapy is known to still have an adverse effect. It is common practice to evaluate Complete Blood Count (CBC) before, during, and after radiotherapy. However, there has been no study regarding the effect of radiotherapy on all CBC parameters. This study aims to analyze the effect of radiotherapy on CBC in NPC patients before and after radiotherapy treatment. Material and methods: This study was an observational study using secondary data from medical records at the radiotherapy outpatient clinic at Dr. Soetomo General Hospital Surabaya. The subject of this study was patients with NPC who underwent a full cycle of radiotherapy treatment on radiotherapy outpatient clinic in 2016. Patients with incomplete medical records and did not finish the radiotherapy treatment were excluded. A paired T-test and Wilcoxon signed-rank test were used for statistical analysis. Results: There were 105 patients included in this study. Mean Corpuscular Hemoglobin Concentration (MCHC), total leucocyte, lymphocyte, and thrombocyte was significantly decreased after a full cycle of radiotherapy (all p <0.05). Eosinophil, basophil, neutrophil, monocyte, Neutrophil to Lymphocyte ratio (NLR), and Platelet to Lymphocyte ratio (PLR) was significantly increased after a full cycle of radiotherapy (all p <0.05). Conclusion: Radiotherapy had a significant effect on the CBC parameter in NPC patients.

Co-Authors Adila Taufik Syamlan Bagus Aulia Mahdi Budi Wicaksono Choirina Windradi Dimas Rio Balti Djohar Nuswantoro Dwiki Novendrianto Esthiningrum Dewi Agustin Etha Dini Widiasi Jovian Philip Swatan Karimah, Azimatul Krisnina Nurul Widiyastuti Mega Kahdina Melinda Masturina Michael Jonatan Pradana Zaky Romadhon Ricardo Adrian Nugraha Ristra Ramadhani Romdhoni, Achmad Chusnu Ryan Enast Intan Sarah Firdausa Satriyo Dwi Suryantoro Sulistia wati Sulistiawati Sulistiawati Tan Nicko Octora Tan Nicko Octora William Putera Sukmajaya Yudha Klahan

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