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All Journal Althea Medical Journal Medical Journal of Indonesia Jurnal Ilmu Kesehatan Masyarakat Folia Medica Indonesiana Damianus Journal of Medicine Universa Medicina JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Nawanto Agung Prastowo
Universitas Katolik Indonesia Atma Jaya, Jakarta
Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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Journal : Universa Medicina

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Dark chocolate administration improves working memory in students Prastowo, Nawanto Agung; Kristanto, Samuel; Sasmita, Poppy Kristina
Universa Medicina Vol 34, No 3 (2015)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2015.v34.229-236

Abstract

BackgroundFlavonoids have positive effects on health, including the nervous system. High flavonoid content can be found in chocolate, especially dark chocolate. Verbal working memory is important for reasoning, language comprehension, planning, and spatial processing. The purpose of this study was to evaluate the effect of a single dose of dark and white chocolate administration on verbal working memory in medical students. MethodsA study of experimental pre-post test design with controls was conducted on 60 students. These were simply randomized into two groups: the first group was supplemented with white chocolate as control, and the second group received dark chocolate, at an identical single dose of 100 g. Working memory was measured with the digit span forwards (DSF) and the digit span backwards (DSB) tests, before, at 1 hour, and at 3 hours after intervention. Independent t and Mann-Whitney tests were used for data analysis. ResultsScores for DSF and DSB in control and treatment groups were similar at baseline. At 1 hour after dark and white chocolate administration, DSF and DSB scores were not significantly different between the two groups (p=0.832; p=0.683). Supplementation of dark chocolate at 3 hours after intervention significantly increased DSB scores compared to white chocolate (p=0.041), but DSF scores were not significantly different between the two groups (p=0.204). ConclusionsDark chocolate as a single dose is capable of improving verbal working memory in students, 3 hours after its consumption. Since cocoa contains multiple bioactive compounds, one approach might be to examine the neurocognitive effects of combinations of potential functional ingredients.
Performance of osteoporosis self-assessment tool in detecting low bone mineral density in menopausal women Haryono, Ignatio Rika; Prastowo, Nawanto Agung
Universa Medicina Vol 36, No 2 (2017)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2017.v36.123-130

Abstract

BackgroundThe osteoporosis self-assessment tool (OST) is a simple screening tool to assess risk of osteoporosis and to select high risk women for dual-energy x-ray absorptiometry (DXA) examination. This study aimed to evaluate OST performance in detecting low bone mineral density (BMD) in menopausal women.MethodsA cross-sectional study involving 60 menopausal women aged 50-65 years. The OST score was calculated from: [weight (kg) – age (yr)] x 0.2. Subjects were classified by OST score into low risk (OST ³2) and high risk (OST< 2) groups. BMD was determined by DXA at 3 bone locations (L1-L4, femoral neck, and total hip). DXA T-scores were categorized into: normal BMD (T-score >-1) and low BMD (T-score £-1). Independent t-test was used to compare subject characteristics between OST groups. Diagnostic performance of OST was evaluated by measuring sensitivity, specificity, positive & negative predictive value (PPV, NPV), positive & negative likelihood ratio (PLR, NLR) and receiver-operating characteristic (ROC). Significance was set at p<0.05.ResultsSubject characteristics and BMD between groups were significantly different (p<0.05). Most subjects (44/73.3%) had high risk of low BMD (OST < 2). Low BMD (T score £-1) was found in 43 subjects (71.7%) at L1-L4, 41 subjects (68.3%) at femoral neck, and 37 subjects (61.7%) at total hip. Diagnostic performance of OST was significant at total hip BMD (sensitivity=0.946, AUC=0.777).Conclusion We conclude that use of the OST score in menopausal women is effective and has adequate sensitivity and specificity. The highest diagnostic performance of OST is on total hip BMD.
Co-Authors Bryan Junius Winata Cindy Leona Wangsa Clarisa Seravine Deni Gunawan Dwi Jani, Dwi Francisca Tjhay Francisca Tjhay Hananta, Linawati Ignatio R. Haryono Ignatio Rika Ignatio Rika Haryono Kidyarto Suryawinata Lydia Esterlita Halim Michelle Olivia Budiarta Nelly Tina Widjaja Peggy Lucida Poppy Kristina Sasmita Regina Regina Rika Haryono Samuel Kristanto, Samuel Stella K. Indra Veronika Maria Sidharta Vetinly Vetinly Vetinly Yessica Mishellin Awaloei