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Journal : EKSAKTA : Jurnal Penelitian dan Pembelajaran MIPA

UJI AKTIVITAS ANTIBAKTERI DARI SEDIAAN KRIM EKSTRAK ETANOL HERBA TUMBUHAN BALSEM (Polygala paniculata L.) TERHADAP BAKTERI Propionebacterium acnes PENYEBAB JERAWAT Helen Anjelina Simanjuntak; Kasta Gurning
Eksakta : Jurnal Penelitian dan Pembelajaran MIPA Vol 5, No 2 (2020): Eksakta : Jurnal Penelitian dan Pembelajaran MIPA
Publisher : Fakultas Keguruan Dan Ilmu Pendidikan, UM-Tapsel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/eksakta.v5i2.133-140

Abstract

Acne is a skin disorder that occurs due to chronic inflammation, which is triggered by the growth of bacteria Propionibacterium acnes. The Balm plant (Polygala paniculata L.) is a small shrub originating from Indonesia. The purpose of this research is to determine the antibacterial activity of the formulation of a cream extract of the herbal ethanol extracts of the balm to the growth of bacteria Propionebacterium acnes. This research is an experimental study with five dosage formulations where the used concentration of extract consists of 0% (F1), 2% (F2), 4% (F3), 6% (F4), VitaCid as a positive control. The testing of antibacterial activity conducted by the CUP-plate technique method. Results showed that the extract of the balm plant in the preparation of cream could inhibit the growth of Propionibacterium acnes, visible with the formation of clear zones. The F1 cream preparations and F2 have stable and F3 categories, F4 has a dominant type.
KARAKTERISASI DAN SKRINING FITOKIMIA DAUN PIRDOT (Saurauia vulcani Korth.) Kasta Gurning; Helen Anjelina Simanjuntak
Eksakta : Jurnal Penelitian dan Pembelajaran MIPA Vol 5, No 2 (2020): Eksakta : Jurnal Penelitian dan Pembelajaran MIPA
Publisher : Fakultas Keguruan Dan Ilmu Pendidikan, UM-Tapsel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/eksakta.v5i2.98-105

Abstract

Pirdot (Saurauia vulcani Korth.) is a plant that has great potential to be developed as raw material for herbal medicines. This study aims to characterize, and phytochemical screening of  (Saurauia vulcani Korth.) leaves. Characterization carried out on the simplistic powder and ethanol extract of pirdot (Saurauia vulcani Korth.). The extraction of pirdot (Saurauia vulcani Korth.) leaves using methanol by the maceration method. Characterization of simplistic and ethanol extract carried out to determine and ensure the appropriateness of the quality standard before it was made into the preparation of a standard drug, while the phytochemical screening was an essential first step in identifying the class of bioactive compounds to direct their potential activities as raw materials in the treatment of various diseases. The simplistic and ethanol extract leaves of pirdot (Saurauia vulcani Korth.) Contain bioactive compounds such as flavonoids, saponins, tannins, and steroids/triterpenoids and ethanol, including suitable solvents in extracting the contents of all bioactive compounds contained in leaves of  pirdot simplisia (Saurauia vulcani Korth.).