Suminar S Achmadi
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Chemical Composition and Anticancer Activity Of the Essential Oil Of Surian Heartwood Rita K Sari; Wasrin Syafii; Suminar S Achmadi; Muhammad Hanafi
Jurnal Ilmu dan Teknologi Kayu Tropis Vol 9, No 2 (2011): Jurnal Ilmu dan Teknologi Kayu Tropis
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (476.853 KB) | DOI: 10.51850/jitkt.v9i2.140

Abstract

Chemical constituents of the essential oil of water and steam distillates of surian heartwood (Toona sinensis) were analyzed by a gas chromatograph-mass spectrometer. Then, the oil was investigated in vitro anticancer bioassay for its possible antioxidant activity by DPPH free radical scavenging and antiproliferative effects by MTT method using Raji lymphoma cancer cell lines (ATCC CCL 86), HeLa cervical cancer cell lines (ATCC CCL2), and Vero normal cell lines (ATCC CCL 81). The essential oil yield from water and steam distillates of surian heartwood was 0.4% (w/w). Thirty-two compounds were identified, that consisted mainly of oxygenated sesquiterpenes (77%). The most representative compounds were spathulenol (21%), isospathulenol (7%), α-cadinol (7%), β-cedrenoxide (6%), and torreyol (5%). The oil showed less effective antioxidant, but the oil had high antiproliferative effects on Raji and HeLa cancer cells with IC50 28 and 134 μg ml-1, respectively when compared to Vero normal cells (IC50 1412 μg ml-1). Our findings suggest that the essential oil of surian heartwood might be considered as a potentially anticancer agent on human cancer cells, especially lymphoma cancer cells.Key words: antioxidant activity, antiproliferative effects, cancer cell lines, essential oil, Toona sinensis
Physical-Mechanical Properties and Bonding Mechanism of Corn Stalks Particleboard with Citric Acid Adhesive Kurnia Wiji Prasetiyo; Linda Oktaviani; Lilik Astari; Firda Aulya Syamani; Subyakto Subyakto; Suminar S Achmadi
Jurnal Ilmu dan Teknologi Kayu Tropis Vol 16, No 2 (2018): Jurnal Ilmu dan Teknologi Kayu Tropis
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1180.28 KB) | DOI: 10.51850/jitkt.v16i2.448

Abstract

As a natural fiber and agricultural by-product, corn stalks (Zea mays saccharata) is considered as an alternative raw material to produce particleboard. Corn stalks is a good source of lignocelluloses, renewable and low cost. This research was aimed to investigate the characteristics of corn stalk particleboard with citric acid as adhesive. This study also evaluated bonding mechanism particle with citric acid and the bonds between celluloses derived corn stalk with citric acid. The boards were manufactured under the hot pressing temperature 200 oC for 10 min. The citric acid concentration was varied in 0, 15, 20 and 25 wt%. The board size and target density were (25 x 25 x 0.9) mm3 and 0.8 g.cm‑3. Results showed that the physical properties of particleboards improved with increasing citric acid concentration up to 20 wt%. At the optimum citric acid content of 20 wt% could provide particleboards with the modulus of rupture, modulus of elasticity and internal bonding satisfied the requirement of the 13 type of the JIS A 5908 (2003) standard. Infrared (IR) spectral analysis from board which manufactured from isolated cellulose was mixed citric acid and pressed on temperature 200 oC showed the presence of ester linkages that the carboxyl and hydroxyl groups of citric acid had reacted with the hydroxyl groups of corn stalk cellulose.