Abdul Kadir
Department Of Otorhinolaryngology Head And Neck Surgery, Faculty Of Medicine, Universitas Hasanuddin, Makassar, Indonesia

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Nata de coco patch miringoplasti pada ruptur membran timpani Syahrijuita s; Abdul Kadir; Sartini s; Marhaen Hardjo
Oto Rhino Laryngologica Indonesiana Vol 48, No 2 (2018): Volume 48, No. 2 July - December 2018
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (333.318 KB) | DOI: 10.32637/orli.v48i2.276

Abstract

Latar belakang: Patch miringoplasti transkanal yang dapat dilakukan di Poli Klinik Telinga Hidung Tenggorok-Kepala Leher (THT-KL), saat ini merupakan pilihan yang didambakan bagi penatalaksanaan ruptur maupun perforasi membran timpani. Tindakan ini sederhana, praktis, tidak memerlukan alat, dan keterampilan khusus, dan dengan biaya yang murah. Membran yang terbuat dari air kelapa dengan bantuan Acetobacter xylinum yang dikenal dengan sebutan Patch Nata de Coco (PNC) memiliki karakteristik mirip kulit manusia yang elastis, biokompabilitas yang baik, non alergenik, dan dapat disterilkan tanpa merusak sifat fisiknya, direkomendasikan menjadi kandidat patch menggantikan patch kertas. Tujuan: Untuk menilai efek penggunaan PNC sebagai patch miringoplasti secara in vivo dan menilai efeknya terhadap waktu penutupan membran timpani (MT) ayam yang ruptur. Metode: Enam membran timpani ayam petelur dengan umur 72-96 minggu, berat badan 1500-2000 gram, telah dilakukan ruptur sejak 3 hari sebelumnya. Dipasangkan PNC transkanal pada 3 MT dan 3 lainnya dibiarkan tanpa perlakuan. Proses dan waktu penutupan didokumentasikan secara elektronik menggunakan otoskop digital. Hasil: Ruptur MT dengan pemasangan  PNC 67% (2MT) menutup pada hari ke-4 dan 100% pada hari ke-5. Ruptur MT tanpa pemasangan  PNC (kontrol) 33% (1MT) menutup pada hari ke-8 dan 100% pada hari ke-10. Waktu penutupan ruptur MT dengan pemasangan PNC  lebih cepat 2x dibanding ruptur MT tanpa pemasangan PNC (kontrol). Kesimpulan: Patch nata de coco dapat digunakan sebagai patch miringoplasti dan dapat mempercepat penutupan ruptur membran timpani pada ayam. Background: The transcanal miringoplasty patch that can be performed at Ear Nose Throat–Head & Neck  Clinic, is currently an ideal choice for the management of rupture and perforation of the tympanic membrane (TM). This procedure is simple, practical, does not require special tools and skill and low cost. The membrane which is made of  coconut water processed with Acetobacter xylinum, is known as  Nata de Coco Patch (NCP). It has    characters of human skin elasticity, good biocompatibility, non-allergenic and can be sterilized without damaging  its physical nature. PNC is recommended to be a  candidate for replacing the paper patch. Purpose: To evaluate  NCP usage in vivo on ruptured chicken TM and the closing time of ruptured TM. Method: Six TM of laying pullet aged 72-96 weeks and body weight 1500-2000 grams were ruptured 3 days previously. Transcanal NCP was installed at 3 perforations, and  3 others were left untreated. The process and TM closuring time was documented electronically using a digital otoscope.  Results: Ruptured  TM with  NCP was closuring 67%  (2 TM) on day 4, and total 100% had closured on the 5th day. Ruptured TM  without NCP (control) was closuring 33%  (1 TM) on day 8, and total 100%  had closured on the 10th day. Ruptured  TM with NCP closed twice faster  than ruptured  TM without NCP (control). Conclusion: Nata de coco patch (NCP) can be used as patch miringoplasty, and it accelerates the closure of the ruptured chicken tympanic membrane.
ACTIVITY OF SUPEROXIDE DISMUTASE ENZYME IN EARLY AND ADVANCED STAGES OF NASOPHARYNGEAL CARCINOMA Gunterus Evans; Abdul Kadir; Riskiana Djamin; Abdul Qadar Punagi; Sutji P. Rahardjo; Mochammad Hatta
INTERNATIONAL JOURNAL OF NASOPHARYNGEAL CARCINOMA Vol. 1 No. 03 (2019): International Journal of Nasopharyngeal Carcinoma
Publisher : TALENTA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijnpc.v1i03.2055

Abstract

Introduction:Nasopharyngeal cancer (NPC) ranks - fourth among all cancers in Indonesia. Objective:This study aimed to determine the levels of SOD in patients with NPC. Material and methods : This was a cross sectional study of analytic observational, using consecutive sampling, with 45 patients with NPC and 15 controls. Results: Average of SOD enzyme levels were higher in the NPC patient group (± 1877.87224 1137.119495) compared with the control group (± 441.42120 320.355669) (p <0.05). SOD enzyme levels were higher in advanced stage ± 2060.67363 1179.147923 compared with early stage ± 1338.86685 680.958439 (p <0.05). Conclusion: The level of SOD enzyme in patients with nasopharyngeal cancer is higher than in the control group, and the level is higher in the advanced stage group than in the early stage group.
Audiogram dan Audiometri Tutur pada Lansia dengan Presbikusis Amrollah Latupono; Eka Savitri; Abdul Kadir
Jurnal Ilmiah Kesehatan (JIKA) Vol. 3 No. 3 (2021): Volume 3 Nomor 3 Desember 2021
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (899.707 KB) | DOI: 10.36590/jika.v3i3.198

Abstract

Presbycusis or age-related hearing loss (ARHL) is one of the biggest health problems suffered by the elderly that causes side effects on the physical, cognitive, emotional, behavioral, and social functions, which will contribute to social isolation, even depression. The purpose of this study was to conduct hearing screening in the elderly diagnosed with presbycusis, determine the audiogram and audiometric features, and describe the characteristics of the elderly and the results of the screening. This was a descriptive study with a cross-sectional research design. Elderly aged 60 to 99 years were screened for hearing by audiogram and speech audiometry after being diagnosed with presbycusis, to analyze the general description of the audiogram and speech audiometry. The results obtained from July to August 2018 showed 61 elderly patients with presbycusis, most were female patients (52%) and were aged 70- 79 (56%). From the right and left ear audiogram screening results, only three patients (5%) had normal audiograms. Other patients have varying degrees of sensorineural hearing loss. Most of the patients (34%) had severe hearing loss in the right ear and moderate hearing loss in the left ear (28%). Based on the speech audiometry, most of the patients (57%) had SDS between 50-80%, which means there is a problem in distinguishing words or language discrimination. This study has successfully performed hearing screening in the elderly with presbycusis. Almost all patients have sensorineural hearing loss with a minimal moderate degree of hearing loss and language discrimination disorder based on the results of the screening.