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All Journal Adi Widya : Jurnal Pengabdian Masyarakat Journal of Dedicators Community JURNAL ILMU KEFARMASIAN INDONESIA Jurnal Farmasetis
MARDIYONO MARDIYONO
UNIVERSITAS SETIA BUDI
Arts Humanities Education Medicine & Pharmacology Public Health Social Sciences Other

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Kombinasi Ekstrak Etanol Buah Mengkudu (Morinda citrifolia L.) dan Daun Pepaya (Carica papaya L.) sebagai Hepatoprotektif selama Pengobatan Tuberkulosis TITIK SUNARNI; RINI PRASTIWI; MARDIYONO MARDIYONO; YUDI RINANTO
JURNAL ILMU KEFARMASIAN INDONESIA Vol 11 No 2 (2013): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.614 KB)

Abstract

Hepatoprotective activity of Morinda citrifolia L. fruits and Carica papaya L. leaves ethanolic extract have been investigated in antituberculosis-induced rats. Forty rats were divided into following eight groups: normal control group was treated with normal feed and water; negative control group was treated with isoniazid and rifampicin, positive control group was treated with isoniazid, rifampicin and Methicol®, and the last five groups were treated with isoniazid, rifampicin and combination of M. citrifolia L. fruits and C. papaya L. leaves extract on various doses. All groups were treated daily for 27 days. Serum levels of bilirubin, alanine aminotransferase (ALT) as well as aspartate aminotransferase (AST) were determined on day -0, 14, 21 and 28 to monitor the liver function. All rats were sacrified on day-28 for liver histology observation. Combination of M. citrifolia extract 20 mg/200 g bw and C. papaya extract 120 mg/200 g bw significantly decreased the serum level of ALT, AST as well as bilirubin. The histology study showed that this combination could prevent the liver damaged based on the lower percentage of necrosis (27.83%), as compared to that of negative control (47.47%).
Dagusibu, P3K (Pertolongan Pertama Pada Kecelakaan) di Rumah dan Penggunaan Antibiotik yang Rasional di Kelurahan Nusukan Ika Purwidyaningrum; Jason Merari Peranginangin; Mardiyono Mardiyono; Jamilah Sarimanah
Journal of Dedicators Community Vol 3, No 1 (2019)
Publisher : Universitas Islam Nahdlatul Ulama Jepara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.582 KB) | DOI: 10.34001/jdc.v3i1.782

Abstract

The purpose of the service activity is to provide information and education to the public about dagusibu, P3K at home and rational use of antibiotics. Health counseling is needed by the community because it is known that the community. The GKSO Movement (Conscious Family Movement) is a program launched by the Indonesian Pharmacists Association (IAI) which is an effort to improve public understanding of medicines through dissemination of medicines, Dagusibu (Get, Use, Save and Dispose) medical equipment, medicine first aid treatment, and knowledge of antibiotics. The service partner, a resident of RT 08 RW 14, lacks awareness in maintaining cleanliness and still does not know the symptoms caused by an illness. The results of dedication show that citizens gain new knowledge and understand the material provided as a purpose of service
Pemanfaatan Larutan Asam Sitrat sebagai Upaya Penurunan Kadar Logam Berat Krom pada Sayuran Kubis Nur Hidayati; Mardiyono Mardiyono; Wimpy Wimpy
Jurnal Farmasetis Vol 11 No 3 (2022): Jurnal Farmasetis: November 2022
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.92 KB)

Abstract

Pencemaran logam berat pada sayuran kubis dapat berasal dari penggunaan pupuk, pestisida, polusi udara, dan penggunaan air untuk irigasi yang tercemar. Toksisitas logam krom dapat menyebabkan karsinogenik, mutasi gen dan teratogenik pada tubuh manusia. Penelitian ini merupakan upaya yang dilakukan untuk menurunkan kadar logam berat krom pada sayuran kubis dengan memanfaatkan larutan asam sitrat. Sampel sayuran kubis yang digunakan adalah lembaran dan potongan, selanjutnya direndam ke dalam larutan asam sitrat dengan variasi konsentrasi (0,0; 0,5 dan 1,0)% dengan waktu perendaman selama 30 dan 60 menit. Kadar logam berat krom ditetapkan secara Spektrofotometri. Hasil penelitian menunjukkan penurunan kadar logam berat krom sampel kubis potongan dalam larutan asam sitrat konsentrasi (0,0; 0,5 dan 1,0)%, perendaman 30 menit adalah (0,00; 21,31 dan 30,07)%; perendaman 60 menit adalah (0,00; 44,26 dan 60,66)%. Persentase penurunan kadar krom sampel kubis lembaran dalam larutan asam sitrat konsentrasi (0,0; 0,5 dan 1,0) %, perendaman 30 menit adalah (0.00; 11,48; 24,59)%, perendaman 60 menit adalah (0,00; 31,15; 50,82)%. Uji statistik menunjukkan ada pengaruh nyata terhadap penurunan kadar logam berat krom dengan perendaman larutan asam sitrat.
PENGELOLAAN SAMPAH RUMAH TANGGA” DI DESA TRIYAGAN KECAMATAN MOJOLABAN KABUPATEN SUKOHARJO Nur Hidayati; Nony Puspawati; Mardiyono Mardiyono; Soebiyanto Soebiyanto
Adi Widya : Jurnal Pengabdian Masyarakat Vol. 7 No. 1 (2023): Adi Widya: Jurnal Pengabdian Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33061/awpm.v7i1.8132

Abstract

The role of the community in waste management at this time is generally limited to waste disposal. We are not yet at the stage of waste management where waste can be reused by the community. Waste management must be handled comprehensively with the 3R principle, namely reduce, namely reducing waste piles; reuse by reusing waste that is not used; and recycle, namely recycling into products of economic value. Good waste management is expected to reduce the volume of waste that is disposed of at the final disposal site (TPA). The need for community education on proper waste management and disposal in order to reduce the impact of environmental pollution.The service was carried out in Triyagan Village, Mojolaban District, Sukoharjo Regency, at the beginning of the activity by giving a pre-test, presenting the material, and at the end of the activity, namely an evaluation with a post-test. The results of the pre-test mean score are 62, and the post-test average score is 82, after receiving counseling. The score of the evaluation results showed that there was a positive change in the mindset of the community.
Penurunan Kadar Nitrit pada Daging Sapi Burger dan Kornet dengan Larutan Vitamin C secara Spektrofotometri Nur Hidayati; Mardiyono Mardiyono
Jurnal Farmasetis Vol 12 No 3 (2023): Jurnal Farmasetis: Agustus 2023
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/far.v12i3.1286

Abstract

Daging sapi olahan burger dan kornet, merupakan makanan cepat saji yang mengandung pengawet nitrit, efek penggunaan nitrit yang berlebihan adalah terbentuknya methemoglobinemia dan menyebabkan kanker. Vitamin C dapat mengoksidasi senyawa nitrit menjadi nitrit oksida. Penelitian ini bertujuan untuk mengetahui pengaruh perendaman dalam larutan vitamin C terhadap penurunan  konsentrasi nitrit dalam daging sapi burger dan kornet. Penelitian menggunakan sampel daging sapi burger dengan kode B dan kornet dengan kode C, selanjutnya masing-masing direndam ke dalam  larutan vitamin C dengan variasi konsentrasi (0,00; 0,30; 0,60; 0,90 dan 1,20) % selama 30 menit. Residu nitrit ditentukan kadarnya menggunakan metode Spektrofotometri.Kadar nitrit awal daging burger (B) sebesar 17,633 ppm mengalami penurunan setelah perendaman dalam larutan vitamin C dengan konsentrasi (0,30; 0,60; 0,90 dan 1,20) % berturut-turut sebesar (22,23; 50,39; 74,16 dan 74,27) %. Daging kornet (C) awal sebesar 14,563 ppm, mengalami penurunan kadar nitrit berturut-turut sebesar (31,83; 60,38; 87,39; 89,72) %. Peningkatan penggunaan konsentrasi larutan vitamin C untuk merendam daging burger dan kornet, maka kadar nitrit semakin menurun.
Co-Authors Jamilah Sarimanah Jason Merari Peranginangin Nony Puspawati Nur Hidayati PURWIDYANINGRUM, IKA RINI PRASTIWI Soebiyanto Soebiyanto Titik Sunarni Wimpy Wimpy Yudi Rinanto