Garuda - Garba Rujukan Digital

SOLID BATH SOAP DOSAGE FORMULATIONS OF THE ETHANOL EXTRACT OF FRESH FRUIT OF MORINDA (MORINDA CITRIFOLIA L.) Yanna Rotua Sihombing; Aminah Syarifudin; Rinaldo Berutu
Jurnal Penelitian Farmasi & Herbal Vol 1 No 1 (2018): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v1i1.60

Morinda plants grow widely throughout the Pasipic and are one of the most significant sources of traditional medicine among the Pacific island community. Morindas contain natural antioxidants for skin health and saponins in the manufacture of soap. Morindas also has potential as an antibacterial (Flavanoid). The purpose of this research is to formulate the ethanol extract of the fruit of morinda (Morinda citrifolia L.) fresh bath soap. Preparations to become solid. This research uses experimental methods. Morinda fruit is extracted by a process of maceration. Solid bath soap preparations inspection conducted this research is test the pH with a concentration of 2,5%, 3,5% and 4,5%. Ethanol extract of the fruit of morindas can be preparations soap formulations in bath with solid inspection results show pH, pH range between 8,5-10,1 show that the solid bath soaps are qualified solid bath soap. The result showed solid bath soap preparations from ethanol extract of the fruit of morinda (Morinda citrifolia L.) fresh with variations in defferent concentrations can be formulated in to a solid bath soap.

UJI IMUNOSTIMULATOR DARI KOMBINASI EKSTRAK ETANOL HERBA BINARA (ARTEMISIA VULGARIS LINN) DAN EKSTRAK ETANOL DAUN PUCUK MERAH (SYZYGIUM OLEANA) DENGAN METODE HIPERSENSITIVITAS TIPE LAMBAT PADA TIKUS Romauli Anna Teresia Marbun; Aminah Syarifuddin; Montysory Silalahi; Radika Bella Fista Ginting
Jurnal Penelitian Farmasi & Herbal Vol 1 No 2 (2019): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v1i2.66

One of the herbs used is herbal binara (Artemisia vulgaris L) which has been studied as a potential immunomodulator with high antioxidant activity. Previous research also stated that red shoots (Syzygium oleana) were studied as potential immunomodulators with high antioxidant activity. Several other species such as Syzygium samarangense have 16 flavonoida compounds which show pharmacological immunological activity. The purpose of this study was to determine the content of secondary metabolites of ethanol extract of herbal binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) and to determine the best dose of extract from the ethanol extract of herbal binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) can reduce the volume of swelling of mouse feet. Examination of the chemical content of secondary metabolites from the ethanol extract of herbal binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) is carried out by chemical screening and characterization of simplicia and extract. The method used is the slow type hypersensitivity method. In this test the independent variable is the secondary metabolite of ethanol extract of herb binara (Artemisia vulgaris L.) with red shoots (Syzygium oleana) with four concentrations (50, 100, 200 and 400 mg / kgBB). The positive control used by Stimuno dose is 32.5 mg / kgBB.

IDENTIFIKASI KADAR VITAMIN C PADA DAGING DAN KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUS) DENGAN METODE SPEKTROFOTOMETRI UV-VISIBLE Aminah Nur Syarifuddin; Rezky Zantrie; Romauli Anna Teresia Marbun
Jurnal FARMASIMED (JFM) Vol 2 No 1 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Introduction: Vitamin C is one of the nutrition acted as a antioxidants and effective addres free radicals can be destructive cells or tissue. Fruits are a source of vitamins C, which is a dragon red. Part of the dragon red during this rarely used is the skin. The dragon fruit is very useful to health, but in fact only thought of as waste farming has yet to be used as a good. This study aims to determine comparison levels of vitamin C on the flesh and the dragon red (Hylocereus polyrhizus) with a method spectrophotometry UV-Visible. Method: This type of research using the method of true experimental reseach stage includes preparation of samples, qualitative test,quantitative test, making the solution of the parent raw materials, determination of wavelength of vitamin C and manufacture of the calibration curve. The sample of this study is the flesh and the dragon red (Hylocereus polyrhizus). Results: Based on the results revealed that the fles and the dragon red (Hylocereus polyrhizus) contain vitamin C. Discussion: Levels of vitamin C on the flesh the dragon red of 0.05888 mg/mL and The levels of vitamin C on the skin the dragon red of 0.02533 mg/mL .

EFEKTIFITAS EKSTRAK ETANOL DAUN SAWI HIJAU (BRASSICA RAPA VAR. PARACHINENSIS) SEBAGAI PELEMBAB KULIT DENGAN SEDIAAN MASKER PEEL-OFF Cucu Arum Dwi Cahya; Aminah Syarifuddin; Ahmad Syukur Syukur
Jurnal FARMASIMED (JFM) Vol 2 No 1 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Green mustard plants can be formulater into peel-off masks to moisturize the skin, because based on previous research green mustard leaves cointain flavonoids as antioxidants which can moisturize the skin. The purpose of this study was to find out green mustard leaves can be formulated into peel-off mask preparations and to find out the preparation and to find out the preparation off peel off mask with etanol extract of green mustard leaves can moisturize the skin. This study uses an experimental method. Green mustard leaves are extracted by maceration. In this study, a skin analyzer was usee as a mesure of skin moisture level after using peel off mask from a variety of dosage formulations which were divided into 5 preparations, blank (without mask, 3%,4%,5%), postive control (using peel off masks on the market). The Anova test results show a sig value of 0,000 or p<0,005 so it is concluded that the variabel has a difference. The conclusion of this study proves that the ethanol extract of green mustard leaves can be used as a peel-off mask for skin moisturizer, where the higher the concentration of mustard leaf extract, the higher the moisture vlue of the skin.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KEMANGI (Ocimum basilicum L.) TERHADAP BAKTERI Streptococcus mutans Aminah Nur Syarifuddin; Rosa Aldora Purba; Novidawati Boru Situmorang; Romauli Anna Teresia Marbun
Jurnal FARMASIMED (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v2i2.368

Introduction: Basil leaf (Ocimum basilicum L.) is one of the most accessible natural plant in Asia such as Indonesia. Basil leaf vegetation contains a lot of flavonoid compounds and essential oils that have the effect as antibacterial because it can inhibit the growth of bacteria Streptococcus mutans cause dental caries. Streptococcus mutans is a round gram-positive bacteria that typically form pairs or chains during its growth. The purpose of this research is to know the antibacterial effectivity of ethanol extract of basil leaves (Ocimum basilicum L.) on the growth of Streptococcus mutans bacteria.This research was conducted with laboratory experimental research method. Basil lean ethanol extract was prepared by using maseration extraction method. Method: The method used in the inhibitory test using diffusion of the disc with 5 samples in each treatment group. The sample consisted of 5 treatment groups, ethanol extract of basil leaves with concentration of 100%, 80%, 60%, 40% and 20%. Result: The result of this study showed that ethanol extract of basil leaves with 100% concentration had inhibitory power of 10,26 mm (strong category), 80% of 9,65 mm (medium category), 60% by 8,12 mm (medium category), 40% by 7,33 mm (medium category), and 20% by 6,90 mm (medium category). Conclusion: The conclusion of this research proves that basil leaf ethanol extract has antibacterial power agains Streptococcus mutans bacteria with effective concentration is 100% with strong category equal to 10,26 mm.

DRP EVALUASI DRUNG RELATED PROBLEMS (DRPs) ANTIBIOTIK PADA PASIEN PNEUMONIA RAWAT INAP ANAK RUMAH SAKIT UMUM DAERAH DELI SERDANG Cindy Monica; Aminah. S; Siti Dalilla
Jurnal FARMASIMED (JFM) Vol 3 No 2 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v3i2.574

Background: Infection is one of the top ten diseases in Indonesia, so that antibiotic therapy is quite high. The increasing use of antibiotics may lead to an increase in the use of irrational antibiotics. Drug Related Problems (DRPs) are events that are not expected from the patient's experience or are suspected to be due to drug therapy so that they have the potential to interfere with the desired healing success. Objective: This study aims to determine the number of occurrences of DRPs which include dosage inaccuracy, namely under and over dose, indication without drug, drug without indication, potential interactions and inaccuracy of drug selection in inpatient pneumonia treatment for children at the Deli Serdang Regional public hospital. In 2019 Method: This study is retrospective in which data is obtained through secondary data in the form of patient medical records for the period January-December 2019 with a cross-sectional study design. The data collection technique was in the form of total sampling, obtained 50 samples that fit the inclusion criteria. Results: Drung Related Problems (DRPs) research that occurred in the under-dose category of drugs (4.0%), and excessive drug doses (2.0%) and no DRPs (94.0%). This shows that the role of pharmacists is important in monitoring patient drug therapy to minimize the occurrence of DRPs.

ANTI-BACTERIAL ACTIVITY TESTING OF ETHANOL EXTRACT 96% PAINAGE SKIN (ANANAS COMOSUS (L.) MERR) AGAINST ESCHERICHIA COLI BACTERIA) Aminah . S; Dewi Abdilantri
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1016

Pineapple peel (Ananas comosus (L.) Merr) is waste form the pineapple fruit. The purpose of this study was to determine the content of pineapple peel extract and to antibacterial activity in various concentrations effective in inhibiting the growth of Escherichia coli. Escherichia coli is a bacterium that generally lives in the large intestine of humans can become a pathogen when it reaches tissues outside the digestive tract which can cause diarrheal disease. The pineapple peel extract is made by using the ectraction method in the form of meceration. The method used in the inhibitory test using the two replication sampels in each treatment groups. The samples consisted of 6 treatment groups is pineapple peel extract concentration 25mg/ml, 50mg/ml, 75mg/ml, and 100mg/ml, as well as positive and negative control. The results obtained from pineapple screening contain alkaloi, flavonoid, tanin, and saponin compounds. The data analysis showsthat pineanepple peel extract concentrations of 25mg/ml, 50mg/ml, 75mg/ml, and 100mg/ml had inhibitory sones with the medium-strong category while ciproloxacin as the control has a strong inhibition zone. The conclusion that while the extract concentration increases, the diameter of the inhibition zone increases.

SOSIALISASI TENTANG EVALUASI DRUG RELATED PROBLEMS (DRPS) ANTIBIOTIK PADA PASIEN PNEUMONIA RAWAT INAP ANAK RSUD DELI SERDANG Cindy Monica; Aminah Syarifuddin
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Infection is the most common disease in Indonesia, so antibiotic therapy is quite high. The increase in the use of antibiotics can lead to an increase in the irrational use of antibiotics. Irrational use can increase the number of bacteria resistance to antibiotics. Drung Related Problems (DRPs) that occur in the category of under-dose drugs (4.0%), and excess drug doses (2.0%) and no DRPs (94.0%). This indicates that the pharmacist's role is important in integrating patient therapy for the occurrence of DRPs.

SOSIALISASI PEMANFAATAN EKSTRAK DAUN SAWO MANILA (Manilkara Zapota) SEBAGAI ANTIBAKTERI TERHADAP BAKTERI Streptococcus Mutans Nur Ulina M. Br. Turnip; Nia Yoseva Sirait; Aminah Syarifuddin; Novandi Purba
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Daun sawo manila merupakan salah satu tanaman yang dapat digunakan sebagai obat tradisional. Daun sawo manila mengandung senyawa metabolit sekunder flavonoid, fenolik, tanin, saponin, yang bersifat sebagai antibakteri. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri pada ekstrak daun sawo manila (Manilkara zapota) terhadap bakteri Streptoccocus mutans. Penelitian ini merupakan penelitian eksperimental laboratorium. Sampel yang digunakan diperoleh dari daun sawo diekstraksi dengan metode maserasi menggunakan pelarut etanol. Metode yang digunakan dalam uji daya hambat antibakteri menggunakan difusi cakram dengan 6 kelompok perlakuan yang terdiri dari konsentrasi 50%, 60%, 70%, 80%, serta Amoxicillin sebagai kontrol positif dan DMSO sebagai kontrol negatif diulang sebanyak 4 kali pengulangan. Parameter yang diamati adalah diameter zona hambat pertumbuhan bakteri Streptococcus mutans. Analisis data menggunakan One way-ANOVA. Hasil penelitian menunjukkan ekstrak etanol daun sawo manila memiliki kemampuan daya hambat antibakteri pada konsentrasi 50% (15,85 mm), 60% (16,45 mm), 70% (17,05 mm), 80% (17,45 mm). Kesimpulan dari penelitian ini membuktikan bahwa ekstrak etanol daun sawo manila memiliki aktivitas daya hambat antibakteri terhadap bakteri Streptococcus mutans.

TRANSPARENT SOAP FORMULATION WITH VARIOUS LEVELS OF CONCENTRATION OF TEAK LEAF EXTRACT (TECTONA GRANDIS L.F.)AS ANTIBACTERIAL SOAP Chandra Pranata; Reno Irwanto; Aminah .S
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1401

The purpose of this study was to examine the organoleptic, homogeneity and antibacterial properties of transparent soap. The treatment used is; F1 (3% teak leaf extract), F2 (6% teak leaf extract), F3 (9% teak leaf extract), and F4 (12% teak leaf extract). The implementation of the research begins with product optimization in advance of the proportion of the use of raw material components. The results of the homogeneity test experiment showed that all formulas were homogeneous and in accordance with SNI standards, then the results of the water content obtained from each preparation proved to meet the requirements set by SNI ( Indonesian National Standard). The results of the pH measurements showed that at pH F0 it remained at 8. The results for measuring pH F1 showed results with a pH of 8. Meanwhile, pH F2 had a pH of 8. The last measurement for pH at pH F3 showed the same pH results as the other formula, namely at pH 8. So that F0, F1, F2, and F3 have the same pH, namely pH 8, where pH 8 is the pH of the positive control, namely soap on the market. Staphylococcus aureus with a concentration of 3% by 13 mm, 6% by 15 mm, 9% by 17 mm, 12% by 20 mm. The greater the concentration of teak leaf extract in transparent solid coir, the greater the inhibition of bacterial growth.

Title

Found 10 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 10 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 10 Documents
Search