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All Journal MEDIA PETERNAKAN - Journal of Animal Science and Technology Majalah Kedokteran Bandung Juke Jurnal Agroindustri Wikrama Parahita : Jurnal Pengabdian Masyarakat Jurnal Teknologi & Industri Hasil Pertanian JURNAL ILMIAH PETERNAKAN TERPADU Jurnal Agrotek Tropika Jurnal Teknologi Pertanian Andalas JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Inovasi Pembangunan Jurnal Pengabdian Fakultas Pertanian Universitas Lampung Jurnal Pengembangan Agroindustri Terapan
Subeki Subeki
Jurusan Teknologi Hasil Pertanian, Fakultas Pertanian, Universitas Lampung
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Journal : Jurnal Pengembangan Agroindustri Terapan

 1 
AN ANTIDIABETIC ACTIVITIES OF CINNAMON EXTRACT IN MICE BY THE METHOD OF INDUCTION OF ALLOXANE M. Perdiansyah Mulia Harahap; Subeki Subeki
Jurnal Pengembangan Agroindustri Terapan Vol 1 No 1 (2022)
Publisher : Politeknik Negeri Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25181/jupiter.v1i1.2657

Abstract

Diabetes mellitus or sugar disease is a metabolic disease with hyperglycemia characteristics that occur due to abnormalities in insulin secretion, insulin work, or both are currently experienced by many Indonesian people. Based on Basic Health Research in Indonesia, diabetics have increased significantly over the past five years.  In 2013, the prevalence rate of diabetes in adults in Indonesia itself, based on the latest data from the 2018 Basic Health Research, in general the prevalence rate of diabetes in adults reached 6.9% and in 2018 the figure increased to 8.5%. This study aims to analyze the antidiabetic activity of cinnamon extract in alloxane-induced mice and the content of bioactive compounds that have antidiabetic activity. Cinnamon extract was carried out by maceration using 96% methanol compounds for 4 weeks followed by ethyl acetate extraction 4 times. Purification was performed using chromatographic columns with solvents CHCl3, 3% MeOH-CHCl3, 20% MeOH-CHCl3, MeOH. Each purification fraction was tested In Vivo on mice. The test results showed that cinnamon powder extract at a fraction of MeOH-CHCl3 3% can significantly reduce blood glucose levels compared to the control treatment of 113: 392  (mg/dL).
Co-Authors - Muhartono - Muhartono . Sumardi Agus Muhamad Hariri Agus Muhammad Hariri Agus Muhammad Hariri, Agus Muhammad Agus Saptomi Amelia Hestiana Anitsa Asrining Puri Carolina Maria Susanti Dewi Sartika Dewi Sartika Eka Yulianita Ekaristi, Teresia Clara Erdi Suroso Gusri Ahyar Ibrahim Gusri Ahyar Ibrahim Hamim Sudarsono Harun Al Rasyid Harun Al Rasyid Harun Al-Rasyid Henrica Agustina Grace Indra Pratama Putra Azis Irwan Sukri Banuwa K. G. Wiryawan M. Perdiansyah Mulia Harahap M. Prayuwidayati Maria Erna Kustyawati Muhammad Ferdiansyah Mulya Harahap Muhartono Muhartono Nur Yasin Nur Yasin Nur Yasin Okta Sekar Ningtyas Ribut Sugiharto Rully Pebriansyah Septianita Eva Rozani Sri Hidayati Sri Setyani Sri Setyani suci hardina rahmawati Susilawati Susilawati T. C. Sunarti Tanto Pratondo Utomo Wisnu Satyajaya Yudha Aditya Mahendra