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Efek toksisitas ekstrak bromelin buah nanas (Ananas comosus L.) dengan metode Brine Shrimp Lethality Test (BSLT) Betty Fitriyasti; Salmi Salmi
EKOTONIA: Jurnal Penelitian Biologi, Botani, Zoologi, dan Mikrobiologi Vol 6 No 1 (2021): Ekotonia: Jurnal Penelitian Biologi, Botani, Zoologi dan Mikrobiologi
Publisher : Department of Biology, Faculty of Agriculture, Fisheries and Biology, University of Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (296.127 KB) | DOI: 10.33019/ekotonia.v6i1.2571

Abstract

Bromelain is proteolytic enzyme extracted from pinepple (Ananas commosus L.) and potents as anticancer. The aimed of this study was to determined the toxicity effect of bromelain extract from pineapple fruit (Ananas commosus L) with brine shrimp lethality test (BSLT) methods. Crude extract of bromelain was obtained by addition of natrium acetat buffer pH 6.5 to pineapple fruit and was setrifugated with 3500 rpm of speed. Bromelain toxiciy was determined by incubated 15 artemia salina Leach (48 aged old) in various concentration of bromelain extract; 3.000 ppm, 2.000 ppm, 1.500 ppm, 1.000 ppm, 500 ppm and 0 ppm for 24 hours. At the end of incubation period, mortality percentages and LC50 were calculated. The result shown that there were increased in mortality percentage as bromelain concentration increased. LC50 value of bromelain exctract was 9.000 ppm. This value indicated that bromelain extract from pineapple fruit had low toxicity effect since its LC50 value were under 1000 ppm. Inconclusion, crude bromelain extract from pineapple fruit did not show anticancer potential based on this study.
Hubungan aktivitas fisik dengan status gizi Siswa SMKN-03 Kabupaten Muko-Muko pada masa pandemi Covid-19 Thesa Dwi Markuri; Salmi Salmi; Haves Ashan
ARGIPA (Arsip Gizi dan Pangan) Vol 6 No 2 (2021)
Publisher : UHAMKA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/argipa.v6i2.6786

Abstract

Overweight and obesity prevalence in Indonesian adolescents tend to increase in the last few decades. The decrease in physical activity is one of the risk factors for this case. Covid-19 pandemic has caused a physical activity decrease in adolescents. This study aimed to determine the relationship between physical activity and nutritional status among the SMKN 03 Muko-Muko students during covid-19 pandemic. This was analytic observational with a cross-sectional study. The study was followed by 76 of 12th grade SMKN 03 Muko-Muko district students that qualified for inclusion and exclusion criteria by purposive sampling. The physical activity level of the subject was determined by Global Physical Activity Questionnaire (GPAQ) and the nutritional status was determined using body mass index (BMI) and categorized based on the Asian-Pacific category. As the result, 69,7% of the subjects had a moderate level of physical activity and 30,3% in high level, respectively. As much as 48,6% of the subjects had normal BMI, 36,8% were underweight and 14,5% were overweight and obese. Statistical analysis by Chi-square concluded that there was a relationship between physical activity and nutritional status among the SMKN-03 Muko-Muko District students during covid-19 pandemic.
Profil Penyakit Malaria di Rumah Sakit Islam Siti Rahmah Padang Tahun 2018 Rahma Triyana Y; Salmi Salmi
Health and Medical Journal Vol 2, No 2 (2020): HEME July 2020
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.065 KB) | DOI: 10.33854/heme.v2i2.452

Abstract

Latar belakang: Penyakit malaria merupakan salah satu masalah kesehatan di Indonesia khususnya Sumatera Barat. Penentuan gambaran penyakit Malaria di suatu daerah dibutuhkan untuk mengetahui penyebaran dan tingkat keparahan penyakit tersebut. Tujuan: Mengetahui distribusi frekuensi menurut usia, jenis kelamin dan tempat tinggal, gambaran jenis Plasmodium penyebab penyakit malaria serta  gambaran hematologi pada pasien malaria di RSI Siti Rahmah Padang tahun 2018. Metode: Jenis penelitian ini merupakan penelitian dengan bentuk studi deskriptif observatorial dengan pendekatan atau disain studi potong lintang (cross sectional). Hasil: Distribusi frekuensi penderita Malaria di RSI Siti Rahmah pada tahun 2018 menurut usia terbanyak terdapat pada kelompok umur 21–30 tahun yaitu sebanyak 28 kasus (36.8%), jenis kelamin terbanyak pada laki-laki sebanyak 46 (60.5%) dan tempat tinggal terbanyak ditemukan di kecamatan Koto Tangah yaitu sebanyak 31 kasus (40.8%). Jenis Plasmodium yang ditemukan pada kasus malaria di RSI Siti Rahmah pada tahun 2018 adalah P. vivax (73 kasus (96.05%)) dan P. falciparum  (3 kasus (3.95%)). Hasil pemeriksaan laboratorium terhadap kadar Hb, hematokrit, trombosit dan leukosit pada pasien positif malaria RSI Siti Rahmah Padang tahun 2018 berada pada rentang normal. Kesimpulan: Distribusi frekuensi penderita Malaria di RSI Siti Rahmah pada tahun 2018 menurut usia terbanyak terdapat pada kelompok umur 21–30 tahun yaitu sebanyak 28 kasus (36.8%), jenis kelamin terbanyak pada laki-laki sebanyak 46 (60.5%) dan tempat tinggal terbanyak ditemukan di Kecamatan Koto Tangah yaitu sebanyak 31 kasus (40.8%). Jenis Plasmodium yang ditemukan pada kasus malaria di RSI Siti Rahmah pada tahun 2018 adalah P. vivax (73 kasus (96.05%) dan P. falciparum  (3 kasus (3.95%)). Hasil pemeriksaan laboratorium terhadap kadar Hb, hematokrit, trombosit dan leukosit pada pasien positif malaria RSI Siti Rahmah Padang tahun 2018 berada pada rentang normal.
PROFIL KANKER PAYUDARA DI RSUP DR M DJAMIL PADANG PADA TAHUN 2019 Melya Susanti; Yustisiana Yustisiana; Salmi Salmi
Nusantara Hasana Journal Vol. 2 No. 2 (2022): Nusantara Hasana Journal, July 2022
Publisher : Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Breast cancer is the most common cancer in women, and is the second most common cancer in the world. The incidence of breast cancer continues to increase every year in both developed and developing countries. The increase in the incidence of breast cancer is thought to be due to an increase in risk factors for breast cancer patients. The risk factors for breast cancer are very multifactorial, including age, gender, genetic factors, reproductive factors, endocrine factors, and dietary factors. In addition, breast cancer also has various types and types, the therapy given is also adjusted to the patient's condition. Amount breast cancer patients come in an advanced stage when  diagnosed the patient has had metastases. This study aims to see how the profile of breast cancer patients at RSUP M DJAMIL in 2019. This research method is descriptive observationalwith a cross-sectional approach. The results of this study were the age of the most breast cancer patients in the age range of 40-49 years (35.1%), the most BMI of breast cancer patients was normal BMI (58.6%), genetic history 99.1%, no family history with breast cancer, the most common stage of breast cancer is stage 4 (63.96%), Invasie ductal carcinoma is the most common type of breast cancer (67.6%), the most common type of therapy is chemotherapy (94%), distant metastases are the most common Most were in the lungs (37.8%). : there are numerous risk  factors causes  breast cancer, the most common type of breast cancer is ductal invasive, patients come already in an advanced stage.
Training on Making Fresh and Preserve Slide-Culture Preparation and Identification of Microscopic Fungi for Senior High School Biology Teachers Monica Kharisma Swandi; Salmi Salmi
Jurnal Pengabdian Masyarakat MIPA dan Pendidikan MIPA Vol 6, No 2 (2022): Vol 6, No 2 (2022)
Publisher : Yogyakarta State University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (419.021 KB)

Abstract

Fresh and preserve slide-culture preparation and identification of microscopic fungi workshop for biology teachers in senior high school was conducted as the community service activity. The aim of this workshop was to improve teachers’s competency by providing a short lecture and training on fresh and preserve slide-culture preparation and identification of microscopic fungi. This workshop was held online using zoom meeting application and divided into four session; short lecture, group activity for identification of fungi, discussion and evaluation. The participant’s knowledge about the topic evaluated two times, before the short lecture and after the discussion session using Google-form. Statistical analysis used paired sample t-test shown that the teachers’s knowledge and skill in identification of microscopic fungi significantly improved after the workshop (p0.05). As the workshop ended, the participant also got a tutorial video, pocketbook and preserved microscopic fungi slide-cluture. We hope the biology teachers can implement all they got during the workshop in learning process at school, so the students can understand the fungi topic better. 
Pelatihan Pembuatan Preparat Segar dan Awetan Jamur Serta Cara Mengidentifikasi Jamur Mikroskopik Bagi Guru Biologi Sekolah Menengah Atas Monica Kharisma Swandi; Salmi Salmi
Jompa Abdi: Jurnal Pengabdian Masyarakat Vol. 1 No. 2 (2022): Jompa Abdi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (612.903 KB) | DOI: 10.55784/jompaabdi.v1i2.101

Abstract

Kegiatan pelatihan pembuatan preparat segar dan awetan jamur serta cara mengidentifikasi jamur mikroskopik bagi Guru Biologi Sekolah Menengah Atas dilaksanakan dalam rangka pengabdian kepada masyarakat. Kegiatan ini bertujuan untuk meningkatkan kompetensi guru biologi melalui kuliah singkat, pelatihan persiapan preparat segar dan awetan serta identifikasi jamur mikroskopik. Pelatihan dilakukan secara daring menggunakan aplikasi zoom meeting dan dilaksanakan dalam 4 sesi : kuliah singkat, kerja kelompok untuk identifikasi jamur, diskusi, dan evaluasi. Tingkat pengetahuan peserta dievaluasi dua kali, sebelum kuliah singkat dan setelah sesi diskusi dengan menggunakan google-form. Analisis secara statistik menggunakan paired sample t-test menunjukkan bahwa adanya peningkatan pengetahuan dan kemahiran peserta dalam mengidentifikasi jamur mikrokopik secara signifikan (p<0.05). Pada akhir pelatihan, peserta juga mendapatkan video pembelajaran, buku saku dan preparat jamur awetan. Kami berharap apa yang diperoleh guru biologi selama mengikuti workshop dapat diaplikasikan pada proses pembelajaran di sekolah masing-masing, sehingga siswa dapat memahami materi jamur dengan lebih mudah.
Efektivitas Larvasida Infusa Bunga Lawang (Illicium Verum) Terhadap Mortalitas Larva Aedes Aegypti Instar III Rahma Triyana; Thesa Andria Putri; Irma Primawati; Melya Susanti; Prima Adelin; Salmi Salmi
Malahayati Nursing Journal Vol 4, No 11 (2022): Volume 4 Nomor 11 2022
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v4i11.8018

Abstract

ABSTRACT Star Anise (Illicium Verum) is a plant that is widely available in Indonesia which is commonly used as a spice, flavorings in drinks, and food flavor enhancers. star anise has the potential as natural larvicides. The purpose of this research was to determine the effectiveness of larvae infusion of star anise on the mortality of Aedes Aegypti larvae. This research covers the field of parasitology, especially in the Entomology section, the research was conducted at the Biomedical Laboratory of Baiturrahmah University, Padang. The research was conducted February - March 2020, the type of research used was experimental research using the Post Test Only Control Group Design. The affordable population of this research was Aedes aegypti instar III larvae which were obtained from the results of colonization in the Health Entomology Laboratory of the Faculty of Veterinary Medicine, Bogor Agricultural University, the total sample needed is 560 larvae, data analysis using one way ANOVA test and probit test. Based on the results of infusion studies, star anise effectively kills larvae of Aedes aegypti instar III at a concentration of 32% to 100% within 24 hours, there is a comparison of the effectiveness of larvicides between the infusion of mace and commercial larvicides (abate). LC50 of larvae infusion of star anise is 7.775% and the LC99 price of larvae infusion of star anise is 53.674%. Evidently, there is a comparison of the effectiveness of larvicides between the infusion of star anise with commercial larvicides (abate). sig 0,000<0.05. key words : Aedes Aegypti Larvae, Star Anise Infusion, LC50, LC99 ABSTRAK Bunga Lawang (Illicium verum) merupakan tumbuhan yang banyak terdapat di Indonesia yang biasa digunakan sebagai bumbu rempah, perisa dalam minuman dan penambah cita rasa masakan. Bunga lawang berpotensi sebagai larvasida alami. Tujuan penelitian ini untuk mengetahui efektivitas larvasida infusa bunga lawang terhadap mortalitas larva Aedes Aegypti. Penelitian ini mencakup bidang ilmu parasitologi khususnya pada bagian Entomologi, penelitian dilakukan di Laboratorium Biomedik Universitas Baiturrahmah Padang. Jenis penelitian yang digunakan adalah penelitian eksperimental dengan menggunakan rancangan Post Test Only Control Group Design, Populasi terjangkau penelitian ini adalah larva Aedes aegypti instar III yang di dapat dari hasil kolonisasi di Laboratorium Entomologi Kesehatan Fakultas Kedokteran Hewan Institut Pertanian Bogor, total sampel yang dibutuhkan adalah 560 ekor larva, analisa data menggunakan uji one way anova dan uji probit. Berdasarkan hasil penelitian Infusa bunga lawang efektif membunuh larva Aedes aegypti instar III pada konsentrasi 32% sebanyak 100% dalam waktu 24 jam. Terdapat perbedaan efektivitas larvasida antara infusa bunga lawang dengan larvasida komersil (abate). LC50 dari larvasida infusa bunga lawang adalah 7,775% dan harga LC99 dari larvasida infusa bunga lawang adalah 53,694%. Kata kunci: Larva Aedes Aegypti, infusa bunga lawang, LC50, LC99
Pengalaman Penderita Hipertensi Dalam Penggunaan Tanaman Obat: Studi Fenomenologi Kamalia Layal; Salmi Salmi
REAL in Nursing Journal Vol 5, No 3 (2022): REAL in Nursing Journal
Publisher : Universitas Fort De Kock Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/rnj.v5i3.2031

Abstract

AbstractHypertension is a degenerative disease and can cause various cardiovascular diseases such as stroke and heart failure which leads to morbidity and mortality.The treatment of hypertension takes a long time, one of the treatments that can help to manage hypertension is complementary alternative therapy using medicinal plants. The aim of this study was to explore the experience of hypertension sufferers in using medicinal plants. The design of this research is qualitative with a phenomenological approach. The participants in this study were 10 patients with hypertension who were diagnosed by a doctor and had used medicinal plants. Data were collected through in-depth interviews and field notes. Data analysis used an interpretive phenomenology approach of Diekelmann, Allen, & Tanner (1989). Four main themes were found: (1) beliefs in medicinal plants; (2) effectiveness and evidence of medicinal plants; (3) utilization of medicinal plants; (4) the supporting and obstacle factors to medicinal plants use. Furthermore, this research can be used as the basic for the furthere research in developing herbal based antihypertensive.Keywords: hypertension, medicinal plants, complementary alternative medicine.
Uji Aktivitas Antibakteri Ekstrak Metanol Daun Paku Resam (Glechenia liearis Burm.) pada Tiga Bakteri Penyebab Akne Vulgaris Salmi Salmi; Monica Kharisma Swandi
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 4, No 2 (2022)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v4i2.30474

Abstract

Abstract: Acne vulgaris or acne is a skin disease caused by a bacterial infection. This study aimed to evaluate the antibacterial activity of methanol extract of paku resam leaves (Gleichenia linearis Burm.) on three different acne-causing bacteria Propionibacterium acnes ATCC 6919, Staphylococcus epidermidis ATCC 12228, and Staphylococcus aureus ATCC 25923. The research consisted of an antibacterial activity test using the disc diffusion method, a minimum inhibitory concentration (MIC) test, a minimum bactericidal concentration (MBC) test, and an equivalence test of antibacterial activity with clindamycin as a positive control. This study found that the methanol extract of paku resam leaves had a significant effect (p<0.05) on inhibiting the growth of the three bacteria at all concentrations tested, namely 2.5; 5; 10; 15; 20; 30%. The MIC value of the extract was lower for P. acnes ATCC 6919 and S. epidermidis ATCC 12228 by 1.63%, compared to S. aureus ATCC 25923 by 3.25%. The KBM value of methanol extract of paku resam leaves was lower for P. acnes ATCC 6919 and S. epidermidis ATCC 12228 (3.25%) compared to S. aureus ATCC 25923 (6.5%). The equivalence test showed that the antibacterial activity of the methanol extract of paku resam did not as strong as clindamycin inhibitory activity to the acne-causing bacteria. In conclusion, the methanolic extract of paku resam leaves has antibacterial activity toward three acne-causing bacteria based on the antibacterial test, MIC, and KBM tests, but its activity was still lessened than clindamycin. Abstrak: Akne vulgaris atau jerawat merupakan salah satu penyakit kulit yang dapat disebabkan oleh infeksi bakteri. Penelitian ini bertujuan untuk mengevaluasi aktivitas antibakteri ekstrak metanol daun paku resam (Glechenia linearis Burm.) pada Propionibacterium acnes ATCC 6919, Staphylococcus epidermidis ATCC 12228 dan Staphylococcus aureus ATCC 25923 bakteri penyebab jerawat. Pengujian terdiri atas uji aktivitas antibakteri dilakukan dengan metode difusi cakram,  uji konsentrasi hambat minimum (KHM), uji konsentrasi bunuh minimum (KBM) dan uji kesetaraan aktivitas antibakteri dengan antibiotik klindamisin sebagai kontrol positif. Hasil penelitian menunjukkan bahwa ekstrak metanol daun paku resam berpengaruh nyata (p<0.05) menekan pertumbuhan ketiga bakteri pada semua konsentrasi yang diujikan yaitu 2.5; 5; 10; 15; 20; 30 %. Nilai KHM ekstrak lebih rendah terhadap P. acnes ATCC 6919 dan S. epidermidis ATCC 12228 sebesar 1.63%, dibandingkan pada S. aureus ATCC 25923 sebesar 3.25%. nilai KBM ekstrak metanol daun paku resam lebih rendah terhadap P. acnes ATCC 6919 dan S. epidermidis ATCC 12228 (3.25%) dibandingkan pada S. aureus ATCC 25923 (6.5%). Hasil uji kesetaraan menunjukkan bahwa aktivitas antibakteri ekstrak metanol paku resam masih lebih rendah dibandingkan klindamisin. Sebagai kesimpulan, ekstrak metanol daun paku resam mampu menghambat pertumbuhan 3 bakteri penyebab jerawat berdasarkan uji antibakteri, KHM dan KBM, namun aktivitasnya masih lebih rendah dibandingkan klindamisin.
OPTIMALISASI USAHA BUDIDAYA JAMUR TIRAM DI DESA TERU MELALUI KEMANDIRIAN PENGADAAN MEDIA TUMBUH DAN PENANAMAN BIBIT JAMUR Anggraeni Anggraeni; Salmi Salmi; Robika Robika; Henny Helmi
Jurnal Pengabdian Masyarakat Borneo Vol 7, No 1 (2023)
Publisher : Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/jpmb.v7i1.2998

Abstract

Jamur tiram (Pleurotus ostreatu) adalah jamur pangan kedua yang banyak dibudidayakan di dunia. Jamur ini memiliki nilai nutrisi yang baik dan nilai ekonomi yang menjanjikan. Kebutuhan konsumsi jamur tiram semakin meningkat namun produksinya masih rendah. Pemerintah Desa Teru, Kecamatan Simpang Katis, Kabupaten Bangka Tengah memandang ini sebagai peluang untuk memberdayakan kaum perempuan di desanya. Kegiatan budidaya jamur dilakukan oleh Ibu-ibu PKK, namun belum maksimal karena tidak memiliki keahlian untuk melakukan pembuatan media tumbuh dan penanaman biibt jamur tiram. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk menciptakan kemandirian budidaya jamur tiram di Desa Teru melalui pelatihan pembuatan media tumbuh dan penanaman bibit jamur. Pelatihan dilakukan dengan metode ceramah dan demonstrasi (praktik) agar peserta mendapat pengalaman lansung. Pendampingan dilakukan mulai dari proses persiapan hingga pemantauan pertumbuhan misselium jamur tiram. Ibu-ibu PKK sebagai peserta pelatihan telah mendapatkan keahlian dalam membuat media tumbuh dan menanam bibit jamur. Sebanyak 73.77% media tumbuh yang diinokulasi pada masa pelatihan menunjukkan adanya pertumbuhan miselium jamur tiram yang bewarna putih.Kata Kunci: bibit jamur, jamur tiram, media tumbuh, pelatihan.