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All Journal Indonesian Journal of Urology Jurnal Kesehatan Andalas Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Jurnal Ilmu Bedah Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Multidisciplinary Science Jurnal Ilmu Kesehatan Indonesia (JIKSI) Indonesian Journal of Cancer
Etriyel Myh
Universitas Andalas
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Journal : Indonesian Journal of Multidisciplinary Science

 1 
The Effect of Ciprofloxacin on Prostate-Specific Antigen (PSA) Andre Dwi Gustiano; Alvarino Alvarino; Etriyel MYH; Peri Eriad Yunir
Indonesian Journal of Multidisciplinary Science Vol. 2 No. 2 (2022): Indonesian Journal of Multidisciplinary Science
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1091.008 KB) | DOI: 10.55324/ijoms.v2i2.279

Abstract

Increased PSA levels can be caused by prostate cancer, prostate infection, and BPH. Several studies report that the use of antibiotics can affect PSA levels. This study aims to determine the effect of ciprofloxacin administration in patients with prostate-specific antigen values ??of 4-10 ng/mL. This was an analytical study with a prospective cohort design. This study was conducted at Dr. M. Djamil Hospital, Padang starting from July 2022 until October 2022. The sampling technique used non-probability sampling with consecutive sampling method. The patient was given the antibiotic ciprofloxacin 2x500 mg for 2 weeks. PSA measurements were carried out before and after administration of antibiotics. There were 20 subject with an average age of 62.65 years (52-79). The mean of initial PSA value was 6.53 ng/mL and the final PSA value was 5.76 ng/mL. There was a significant difference between PSA levels before and after administration of ciprofloxacin (p=0.000). The use of antibiotics in patients with PSA levels of 4-10 ng/ml can reduce PSA levels.
IPP and Changes in IPSS in Benign Prostatic Hyperplasia (BPH) Patients Treated with ?1-Blocker Muhammad Ishak; Etriyel MYH; Peri Eriad Yunir
Indonesian Journal of Multidisciplinary Science Vol. 2 No. 4 (2023): Indonesian Journal of Multidisciplinary Science
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (993.507 KB) | DOI: 10.55324/ijoms.v2i4.416

Abstract

Benign prostatic hyperplasia (BPH) is a benign enlargement of the prostate gland caused by the proliferation of epithelial cells and stroma, causing Lower Urinary Tract Symptoms (LUTS). One of the ways to treat BPH is through medical therapy with ?1-blockers. The success of medical therapy is influenced by many factors, one of which is Intravesical Prostatic Protrusion (IPP).  This study was a comparative prospective study that aimed to find the effect of IPP on response to therapy with ?1-blockers in BPH patients. IPSS was used as a measuring tool. IPP was examined using transabdominal ultrasound. The study was conducted from July 2020 to December 2020. Data were analyzed using the one way ANOVA average comparison test and Pearson correlation test. A sample of 30 patients was divided into 3 groups based on the IPP degree, namely grade I (<5mm), grade II (5-10mm) and grade III (> 10mm). There were no significant differences in the mean initial IPSS scores in each group, namely 19.6, 18.90, and 21.30 (p = 0.216). There was a significant decrease in mean IPSS after 1 month of ?1-blocker therapy. In addition, there was also found a significant correlation between the IPP value and the decrease in the final IPSS with a negative correlation. There is a significant correlation between the IPP degree and the decrease in IPSS in BPH patients after receiving ?1-blocker therapy as the higher the IPP degree, the lower the final IPSS improvement.
Co-Authors Aldeno Wahyu Anandi Alvarino Alvarino Alvarino Alvarino Anak Agung Istri Sri Wiadnyani Andre Dwi Gustiano Arina Widya Murni Aswiyanti Asri David Manuputty Dody Efmansyah Ennesta Asri Hafizar Hafizar Henny Mulyani Husna Yetti Muhammad Ishak Muhammad Ishak Muhammad Raihan Farrasky Peri Eriad Yunir Peri Eriad Yunir Peri Eriad Yunir Peri Eriad Yunir Rahmens Syamun Rani Novelty Rinal Effendi Salma Nabilaputri Nadiaskara Siska Rama Zirti Sonny Hardian Wiradinata, Indra Yenita Afriyeni Yevri Zulfiqar Zelly Dia Rofinda Zulfiqar, Yefri