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All Journal Jurnal Teknosains Majalah Obat Tradisional JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Chemistry Indonesian Journal of Chemical Research Al-Khidmah Journal of Tropical Pharmacy and Chemistry PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Acta Chimica Asiana Jurnal Sains dan Kesehatan Media Farmasi Indonesia Jurnal Farmasi Sains dan Praktis Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Bambang WIJIANTO
Universitas Tanjungpura
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences Other

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Pemanfaatan Rambut Jagung (Zea mays L.) Menjadi Teh Herbal “KoNsilk” kepada Kader Puskesmas Perumnas 2 Kota Pontianak: Utilization of Corn Silk (Zea mays L.) Into "KoNsilk" Herbal Tea for Cadres of Public Health Center 2 Pontianak City Bambang Wijianto; Andhi Fahrurroji; Muhammad Akib Yuswar; Hafrizal Riza
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 8 No. 1 (2023): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v8i1.4205

Abstract

The impact of the Covid-19 pandemic is felt by the people of Pontianak, in the economic, sociocultural, and health fields. One of the prime commodities in Pontianak is corn farming. The aim of the PKM Program is to innovate corn-based processed products. This PKM activity began with outreach to the heads and employees of the Puskesmas, as well as identifying health cadres as potential participants in training related to using corn silk as herbal tea drinks. Training on using corn silk as herbal tea drinks for cadres was carried out offline and interactively using leaflets, videos, and hands-on practice. Evaluation and monitoring activities are carried out using a Google form (pre-test and post-test). The results of the PKM activity showed success in understanding the cadres with good knowledge when the pre-test was carried out by only ten people (30.30%). After being given knowledge training, respondents in the good category amounted to 30 people (90.90%). PKM activities targeting UPT Puskesmas Perum II cadres increased the ability of cadres to utilize corn silk waste in herbal tea. The next activity is expected to be able to assist so that the resulting product obtains a permit.
UJI ANTIOKSIDAN EKSTRAK METANOL SIPUT ONCHIDIID (Onchidium typhae) DENGAN METODE DPPH Guci Intan Kemuning; Bambang Wijianto; Andhi Fahrurroji
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 2 No 1 (2023): Januari : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Ekonomi Trianandra

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1622.698 KB) | DOI: 10.55606/klinik.v2i1.794

Abstract

Siput Onchidid (Onchidium typhae) merupakan spesies dalam kelas gastropoda yang dapat ditemukan di daerah pesisir pulau Buton dan juga Madura dan Kalimantan Barat.. Siput onchidid diketahui memiliki kandungan metabolit sekunder berupa steroid yang dapat berpotensi sebagai antioksdian. Penelitian ini membahas tentang uji antioksidan di dalam siput onchidid dengan metode DPPH (1,1- diphenil-2-pikrilhirazil) dengan menggunakan pelarut methanol dan pengujian skrining senyawa metabolik ekstrak dengan uji fitokimia pada ekstrak yang meliputi uji steroid, alkaloid, dan steroid. Hasil pengujian didapat bahwa ekstrak metanol siput onchidid memiliki terdapat senyawa metabolik sekunder dari golongan alkaloid dan steroid yang ditandai dengan reaksi positif. Hasil uji antioksidan dengan metode DPPH dengan senyawa pembanding vitamin C. Penelitian menunjukkan besar aktivitas antioksidan ekstrak metanol siput onchidid yang dinyatakan dengan nilai IC50 sebesar 92,045 yang dikategorikan antioksidan kategori kuat.
Study of Anthocyanin Molecule Blocking as Anti-Hypertensive through the Pathway of the Renin-Angiotensin-Aldosterone System (RAAS) Dwi Budiarto; Bambang Wijianto; Hariyanto IH
Indonesian Journal of Chemical Research Vol 11 No 1 (2023): Edition for May 2023
Publisher : Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598//ijcr.2023.11-bud

Abstract

Anthocyanins are flavonoid-derived compounds that can reduce blood pressure. This study aims to determine the affinity value of the compound to bind to Angiotensin Converting Enzyme (ACE) and bind to Angiotensin II type 1 Receptor (AT1R) and to determine the distance and shape of the bond that occurs. The results of anthocyanin-derived compounds Delphinidin, Petunidin, Malvidin, Cyanidin, Peonidin, and Pelargonidin have anti-hypertensive potential through the Renin Angiotensin Aldosterone (RAAS) pathway based on molecular docking calculations. The affinity value of each, against Angiotensin Converting Enzyme (ACE) -7.7; -7.8; -7.7; -7.7; -7.8, and -7.7, the best affinity value in anthocyanin-derived compounds is shown in the Malvidin test compound which has three types of hydrogen bonds at a distance of ± 2 Å (ASP377, TYR520, ASP415) and has 1 type of bond that is the same as the lisinopril control (TYR520). While the affinity value to Angiotensin Receptor (AT1R) is -7.7; -7.7; -7.8; -7.7; -7.8, and -7.6, respectively, the best affinity value is shown in the Malvidin test ligand compound of -7.8 kcal/mol which has four types of hydrogen bonds ± 2 Å distance (TYR92, SER105, ARG167, TRP84) and has one kind of bond in common with lisinopril control (TYR520).
Studi docking untuk skrining senyawa antibakteri dari Jeringau Merah (Acorus calamus L.) menggunakan protein Shigella flexneri sebagai model sistem Riyadh Aqilsya Amaryl Dyas; Bambang Wijianto; Hariyanto IH
Acta Chimica Asiana Vol. 6 No. 2 (2023)
Publisher : The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v6i2.161

Abstract

Alpha (a) and beta (β) asarone were identified as the main compounds of red Jeringau (Acorus calamus L.) and had antimicrobial properties. This study aimed to know these two compounds' antibacterial mechanism and toxicity prediction against the PBP 2 protein and 50S Ribosomal Protein of Shigella flexneri. Molecular docking protocol using PyRx device was performed with Exhaustiveness value= 106, grid x=38.738375, y=112.645792, z=46.926417 for PBP2, and grid x=71.721251, y=47.551601, z=9.663173 for 50S Ribosomal Protein. The molecular docking results on the α -Asarone compound obtained an affinity value of -5.7 kcal/mol for PBP2 and an affinity value of -5.6 kcal/mol for 50S Ribosomal Protein. In comparison, β-Asarone had an affinity value of -5.6 kcal/mol to PBP2 and an affinity value of -5.7 kcal/mol for 50S Ribosomal Protein. The α and β-Asarone affinity had better values than the control. Molecular docking of α and β-Asarone compounds results in ionic bonds to the TYR529 amino acid and polar bonds to the ASN552 amino acid of PBP2. However, only β-Asarone produces ionic bonds at the amino acid ILE17 and polar bonds at GLU13 from 50S Ribosomal Protein. Based on this study, the α and β-Asarone compounds were shown to have antibacterial activity by interfering with the permeability of the bacterial cell wall. Both compounds are also predicted to have carcinogenic and mutagen effects.
UJI ANTIOKSIDAN EKSTRAK METANOL SIPUT ONCHIDIID (Onchidium typhae) DENGAN METODE DPPH Guci Intan Kemuning; Bambang Wijianto; Andhi Fahrurroji
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 2 No. 3 (2022): NOVEMBER : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Amik Veteran Porwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v2i3.810

Abstract

Siput Onchidid (Onchidium typhae) merupakan spesies dalam kelas gastropoda yang dapat ditemukan di daerah pesisir pulau Buton dan juga Madura dan Kalimantan Barat.. Siput onchidid diketahui memiliki kandungan metabolit sekunder berupa steroid yang dapat berpotensi sebagai antioksdian. Penelitian ini membahas tentang uji antioksidan di dalam siput onchidid dengan metode DPPH (1,1- diphenil-2-pikrilhirazil) dengan menggunakan pelarut methanol dan pengujian skrining senyawa metabolik ekstrak dengan uji fitokimia pada ekstrak yang meliputi uji steroid, alkaloid, dan steroid. Hasil pengujian didapat bahwa ekstrak metanol siput onchidid memiliki terdapat senyawa metabolik sekunder dari golongan alkaloid dan steroid yang ditandai dengan reaksi positif. Hasil uji antioksidan dengan metode DPPH dengan senyawa pembanding vitamin C. Penelitian menunjukkan besar aktivitas antioksidan ekstrak metanol siput onchidid yang dinyatakan dengan nilai IC50 sebesar 92,045 yang dikategorikan antioksidan kategori kuat.
Cosmetic Serum Loaded Arabica Coffee (Coffea arabica) Extract: Formulation and Antioxidant Study Harum Nadyanti Usman; Liza Pratiwi; Bambang Wijianto
Majalah Obat Tradisional Vol 28, No 2 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.83120

Abstract

Arabica coffee (Coffea arabica) is a natural antioxidant that can be used in the prevention of skin aging. This study was conducted to determine the comparison of variations in the composition of HPMC, CMC-Na, and Carbomer in the optimum formula of arabica coffee serum, then to determine the physical properties of the preparation, as well as the IC50 value ofarabica coffee extract and arabica coffee serum in the DPPH test. Arabica coffee extract was obtained by maceration method using 70% ethanol. Determination of the optimum formula of arabica coffee serum using the Simplex Lattice Design method. The optimum formula of arabica coffee serum was evaluated for physical properties including organoleptic test, homogeneity test, pH test, spreadability test, and adhesion test. The antioxidant activity of arabica coffee extract and the optimum formula of arabica coffee serum was tested using the DPPH method. Data analysis used SPSS One sample T-test statistics. The results showed that the composition variation of HPMC, CMC-Na, and Carbomer in the optimum formula of arabica coffee serum using the Simplex Lattice Design method was 0.1%:0.8%:0.1%. The resulting predicted values are a pH value of 4.88 and a spreadability value of 7.95 cm. The optimum formula of arabica coffee serum has the physical properties of the preparation, namely brown color, coffee aroma, light texture, a cool sensation when applied to the skin, homogeneous, has a spreadability of 7.93 cm, stickiness of 1 second, and pH value of 4.9. The IC50 value of arabica coffee extract and the optimum formula of arabica coffee serum are 8.13 ppm and 250 ppm. The results of the SPSS One sample T-test statistical analysis showed that there was no significant difference between the prediction response and the results of the optimum formula evaluation.
Edukasi Pencegahan Bullying kepada Siswa SDN 01 Rasau Jaya Kubu Raya: Bullying Prevention Education for Students at SDN 01 Rasau Jaya Kubu Raya Bambang Wijianto; Intan Yap; Risa Indriyani; Virna Helena Damanik; Inggrid Aprilia Manullang; Dimas Achmad Mu’arif
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 8 No. 5 (2023): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v8i5.4828

Abstract

Bullying in children can be classified as abnormal behavior that can affect the mental health of both the perpetrator and the victim. The village of Rasau Jaya I is a thriving transmigration area as a cultural, economic, and social center, including education with varied cultural, cultural, and social impacts. The Community Service Program (PKM) is designed to increase the knowledge of elementary students in grades 3 to 5 of SDN 01 Rasau Jaya in recognizing and preventing bullying in the school environment. This service program provides education using learning media such as posters and leaflets, lectures, question-and-answer discussions, and mini quizzes. The PKM program is conducted in groups, interactively and directly with students. Evaluation and monitoring activities were carried out using questionnaires (pre-test and post-test), which were analyzed descriptively and measured the ability of students to answer the questionnaire. The evaluation results show that there is an increase in the level of knowledge of students in recognizing and preventing bullying at school.
Characterization of Onchidiid Slug (Onchidium typhae) West Kalimantan Waters as Antibacterials and Antifungal Bambang Wijianto; Hasyrul Hamzah; Annisa Larasati Nurhidayah; Guci Intan Kemuning; Riyadh Aqilsya Amaryl Dyas
Borneo Journal of Pharmacy Vol. 5 No. 1 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i1.2936

Abstract

Onchidiid slug (Onchidium typhae) is a nudibranch that coastal communities in West Kalimantan have widely used as wounds. The study aims to characterize the West Kalimantan water O. typhae as antibacterial and antifungal. The study of O. typhae was carried out in several stages: preparation and optimization, extraction by Quinn method, characterization and identification of bioactive compounds, and antibacterial and antifungal assay using the microdilution method. The result of the proximate test showed that O. typhae powder contains high protein, namely 67.68%. Phytochemical screening results from methanol, ethyl acetate, and chloroform extracts contain alkaloids and amino acids. Methanol, chloroform, and ethyl acetate extract 1% of O. typhae showed inhibitory activity against Staphylococcus aureus, Escherichia coli, and Candida albicans. The most significant inhibition value was indicated by chloroform extract 1%, where the inhibition value against S. aureus, E. coli, and C. albicans was 82±0.01%; 85.8±0.01%; 85±0.01%, respectively. From these results, O. typhae powder can be developed as a wound medicine through its antibacterial and antifungal activity.
Pelatihan Pembuatan Nano Liquid Aromaterapi bagi Kader PKK Desa Wajok Hilir di Kabupaten Mempawah: Training on Manufacturing Aromatherapy Nano liquid for PKK Cadres in Wajok Hilir Village in Mempawah District Liza Pratiwi; Bambang Wijianto; Andhi Fahrurroji; Muhammad Akib Yuswar
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 3 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i3.6251

Abstract

So far, essential oils have only been used as perfume and sold as raw material. On average, residents of Wajok Hilir village have yards covered with essential oil-producing plants such as lavender, lemongrass, and coconut. The aim of the PKM Program is training in utilizing community resources to make essential oils for aromatherapy in nano-liquid preparations. The development of this product must be oriented towards developing a practice that is easy to apply and environmentally friendly without ignoring environmental health. The solution to overcome existing problems is to provide knowledge to partners about the benefits of nano liquid preparations as aromatherapy and mosquito repellent and training on using essential oils as aromatherapy. Pharmacists provided training on making "nano liquid" products. This training activity will involve PKK cadres from Wajok Hilir village. The output target of this activity is to increase the level of quality empowerment of partners by driving sustainable activity programs from product results. This service activity showed that the 31 participants comprised the majority of women and homemakers, 77.4% with a high school education level. The results of measuring participants' knowledge and skills showed an increase in the pre-test and post-test scores, which were 55.5 and 78.33, respectively. In conclusion, the service activities that have been carried out have increased the knowledge and abilities of participants regarding the use of essential oils as aromatherapy in the form of nano-liquid preparations.
SERUM OF EXTRACT Onchidium Typhae USES HYDROXYETHYL CELLULOSE AND CARBOXYMETHYL CELLULOSE NATRIUM BASE AS ANTIOXIDANT Bambang Wijianto; Liza Pratiwi
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.1113

Abstract

Antioxidants can prevent premature aging (anti-aging) and various types of cancer and increase body immunity. Empirically, Onchidiid slugs have been used as natural antioxidants. This study aimed to determine the antioxidant potency of the serum of Onchidiid slug ethanolic extract. The Onchidiid slug extract was obtained by maceration and was prepared to create two effective serum formulations. Formula A involved hydroxyethyl cellulose (HEC), while Formula B employed sodium carboxymethyl cellulose (Na-CMC) as gelling agent. The second serum formula was rigorously evaluated and subjected to antioxidant activity testing by the diphenyl-2-picrylhydrazyl (DPPH) method. The serum preparation with the best physical properties and antioxidant activity was serum A at a concentration of 1%. Physical test results showed that serum A had a yellow color with a distinctive smell and was homogeneous with a soft texture. The test results for the spreadability and stickiness properties of serum A were 6 cm2 and 1'55'' second. The serum A antioxidant activity test results showed moderate free-radical scavenging activity, with an IC50 value of 277 ppm. Keywords: Anti-aging, 2,2-diphenyl-1-pikrilhidrazyl, Onchidium typhae, Antioxidant
Co-Authors Agus Setyawan Agus Styawan Andhi Fahrurroji Andhi Fahrurroji Andhi Fahrurroji Andhi Fahrurroji Annisa Larasati Nurhidayah Annisa Larasati Nurhidayah Audrey Thendralie Ayu Setyaningrum Dimas Achmad Mu’arif Dwi Budiarto Emy OKTAVIANI Fajar Nugraha Guci Intan Kemuning Hadi Kurniawan Hafrizal Riza Hamzah, Hasyrul Hariyanto IH Harum Nadyanti Usman Inggrid Aprilia Manullang Intan Yap Lidya Hafidzah Putri Liza Pratiwi Luliana, Sri Lurizma Putri Adinda Mohamad Andrie Muhammad Akib Yuswar Nanda Paramita Pinondang Simaremare Pinondang Simaremare, Pinondang Randi Mulyana Putra Risa Indriyani Riyadh Aqilsya Amaryl Dyas Riyadh Aqilsya Amaryl Dyas Virna Helena Damanik