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All Journal Journal of Dentomaxillofacial Science MDJ (Makassar Dental Journal)
Marhamah Marhamah
Bagian Ilmu Kedokteran Gigi Anak, Fakultas Kedokteran Gigi Universitas Hasanuddin, Makassar
Dentistry

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SP-C1 tongue squamous cell carcinoma, ethanol fraction of ant nest plant, proliferation Harun Achmad; Supriatno Supriatno; Marhamah Marhamah; Rasmidar Rasmidar
Journal of Dentomaxillofacial Science Vol. 13 No. 1 (2014): Formerly Jurnal Dentofasial ISSN 1412-8926
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v13i1.378

Abstract

Squamous cell carcinoma at the tongue is a malignant tumor derived from epithelial mucosa of the oral cavity. Thisstudy aims to identify and to analyze the effect of flavonoid fraction of etanol of ant nests plants (Myrmecodia pendans)as an anti-cancer barrier against the proliferation of SP-C1 tongue cancer cells. The study was conducted with pureexperimental laboratory methods using Supri's-Clone 1 (SP-C1) human tongue cancer cells cultured. Researchgradually begins with determination, extraction and fractionation ant nests plant, cytotoxicity test to get a fraction offlavonoids that have anticancer potential,and finaly testing the proliferation barriers. Cytotoxicity test showed thatfrom the highest concentration (1000 μg/mL) to the lowest concentration (7.8125 μg/mL) in etanol fraction, fractionhexan and water caused Sp-C1 human tongue cancer cells death significantly. Ethanol fraction LCvalues of 938,003.These results were obtained from the linear equivalent of the relation between log consentration and probit. Flavonoidetanol fraction of ant nest has an inhibition effect against proliferation of SP-C1. Antiproliferative analysis of flavonoidfraction of ethanol flavonoid based on concentration and incubation time on optical density absorbation SP-C1 cellswas statistically highly significant (p=0.00).
Malocclusion: prevention and treatment during growth and development: Maloklusi: pencegahan dan penanganannya pada masa tumbuh kembang Yayah Inayah; Sherly Horax; Fajriani; Marhamah; Eka Erwansyah
Makassar Dental Journal Vol. 10 No. 3 (2021): Volume 10 Issue 3 Desember 2021
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v10i3.462

Abstract

Malocclusion is a common condition in the world's population but is not considered as a normal condition. A normal dentofacial development depends on the normal function of the muscles around the mouth, the balance between the muscles of the lips, cheeks from the outside of the dental arch and the inside of the tongue needs to be maintained. The imbalance of the three orofa-cial muscles will affect the development of dentofacial structures. Malocclusion occurs due to several factors including genetic factors and environmental factors. Prevention of malocclusion can be done in several ways, namely eliminating prolonged bad habits and improving nutrition during pregnancy. If malocclusion has occurred, treatment is carried out as early as possible so as not to aggravate the malocclusion.
Early detection and manifestation of leukemia in the oral cavity of the child: Deteksi dini dan manifestasi leukemia pada rongga mulut anak Yayah Inayah; Sumintarti; Sherly Horax; Fajriani; Marhamah
Makassar Dental Journal Vol. 10 No. 3 (2021): Volume 10 Issue 3 Desember 2021
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v10i3.466

Abstract

Cancer is a chronic disease and is the third leading cause of death in children aged 1-14 years. About one third of cancer in child-ren is leukemia with an incidence of 9 cases per 100,000 population. Leukemia is a malignancy of blood cells originating from the bone marrow and can occur in children and adults. Early detection of oral lesions is very important for the prevention and treatment of complications that may arise during therapy, a better prognosis, lower morbidity and mortality for that disease. Oral manifestations of leukemia are gingival enlargement and spontaneous bleeding, oral ulceration, petechiae, hematoma and pale mucosa. Oral lesions occur in both acute and chronic forms of all types of leukemia and are more common in the acute stage. Dental care for patients with leukemia should be focused on preventing injury, local control of gingival bleeding by re-moving the biofilm, and prevention of oral infection. Oral hygiene by brushing teeth, use of fluoride, and a non-cariogenic diet should also be emphasized during treatment.
Co-Authors Eka Erwansyah Fajriani Harun Achmad Rasmidar Samad Sherly Horax Sumintarti Sumintarti Supriatno Supriatno Yayah Inayah