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Faktor – Faktor Terkait Tingkat Keparahan Infeksi Coronavirus Disease 2019 (COVID-19): Sebuah Kajian Literatur Abiyyu Didar Haq; Adli Putra Nugraha; I Komang Gede Andhika Wibisana; Febbi Anggy; Fiana Damayanti; R.R. Ditya Mutiara Syifa; Ni Putu Visty Widhiani; Cut Warnaini
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 9 No 1 (2021): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 9.1 Edisi Maret - Juli
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v9i1.338

Abstract

Background: COVID-19 pandemic that started in the early 2020 triggers the declaration of Public Health Emergency of International Concern (PHEIC) by WHO. Caused by SARS-CoV-2 virus, COVID-19 mainly infects the respiratory tract by binding to the ACE2 receptor. COVID-19 infection can cause many clinical manifestation from no symptom to severe life-threatening symptom depending on many factors. Factors that can determine the severity of clinical manifestation is urgently needed to be recognized by our clinician in order to be able to anticipate patient’s condition before the severe clinical manifestation even begins. This literature review is aimed to summarize and discuss some factors that are most often showed up and determined the severity of COVID-19 infection. Methods: This literature review uses journal article that are sourced from online databases such as PubMed and Google Scholar. The type of article that will be chosen are research article, systematic review and meta-analysis, narrative review, and literature review with the topic of transmission, clinical manifestasion, pathogenesis, immune response, and severity risk factor of COVID-19. Discussion: From our literature search, it is concluded that the factors that are most likely to determine the severity of COVID-19 infection is age, comorbid disease, vitamin D deficiency, and obesity. These four factors are not four independent factors but rather overlapping and interconnecting factors that determines the severity of COVID-19 infection. Conclusion: Most of the factors that determined the severity of COVID-19 mainly are easily preventable factors. Therefore, the knowledge and awareness of our clinician about these factors will really helps anticipating the severe clinical manifestation among COVID-19 patients before the manifestation even starts to appear.
Suicidal Risk in People with Obsessive Compulsive Disorder Wardha Novia Annisa; Athalita Andhera Nabil; I Komang Gede Andhika Wibisana; Sima Smith; Emmy Amalia
Jurnal Biologi Tropis Vol. 23 No. 4 (2023): October - December
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i4.5602

Abstract

Obsessive compulsive disorder or Obsessive Compulsive Disorder (OCD) is a psychiatric disorder characterized by excessive anxiety, persistent thoughts (obsessions), and repetitive behaviors (compulsions). The prevalence of OCD in Europe ranges from 0.1-2.3% annually and more common in adults. The risk of suicide increases ten times more in OCD sufferers compared to the non-OCD sufferers with prevalence the OCD sufferers who has thoughts of suicide is 23.3%. This literature review aims to determine the risk factors for suicide in OCD patients so that prevention can be carried out in individuals who have risk factors. In this literature review we conducted a search on the PubMed,  Google Schoolar, and Researchgate database  using  the search keyword “Obsessive Compulsive Disorder”, “Obsessive Compulsive Symptoms”, “Suicide”, “Self-murder”, and “Risk Factor”. OCD is a disease with genetic and non-genetic risk factors, can manifest clinically as obsessions and compulsions that occur due to failure in responding to yedasantience signals so that the security motivation system (SMS) will be activated longer than normal. The longer SMS activated, the more depressive symptoms can develop, which tends to give rise to suicidal thoughts. In conclusion, risk factors for suicide in OCD that can be identified earlier will not only help the patient's prognosis but also help them choose treatment steps that are appropriate with the severity of the OCD symptoms.
Gastrointestinal Tract Malrotation: Etiology and Risk Factors Annisa Yumna Nabiilah; Dewa Ayu Vania; I Komang Gede Andhika Wibisana; Rizqina Alya Shafa; Sicilia Putri Atari; Zikrul Haikal
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i1.5761

Abstract

Malrotation is a congenital abnormal position of the intestine within the peritoneal cavity and usually involves the small intestine and large intestine. Intestinal malrotation occurs at a rate of 1 in 500 live births. Male predominance was present in neonates with a male-to-female ratio of 2:1. Up to 40% of patients with malrotation present within the first week of life, 50% up to one month of age and 75% by one year of age. Purpose: To determine the etiology and risk factors for gastrointestinal tract malrotation. Conclusion: Malrotation is a congenital abnormal position of the intestine within the peritoneal cavity and usually involves the small intestine and large intestine. Gastrointestinal (GI) malrotation, sometimes referred to as incomplete rotation or non- rotation of the bowel, is any deviation from the physiological rotation and/or fixation of the GI tract during embryonic development. During the development of the GI tract, the 3 parts of the tract, namely the foregut, middle, and hindgut, usually protrude from the abdominal cavity and undergo a counterclockwise rotation of 270 degrees. Basically, rotational and fixation anomalies are caused by failure of various embryological stages. Clinical manifestations are divided into 4, namely Midgu Volvulus, Intestinal Obstruction, Gasroschisis, and Omphalocele. The main management of intestinal malrotation is a surgical procedure. Other therapies are given to stabilize the patient and are supportive.