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All Journal JSI: Jurnal Sistem Informasi (E-Journal) Karya Ilmiah S.1 Ilmu Keperawatan Jurnal Ilmiah Mahasiswa FKIP Prodi Biologi Journal of Biology Education Prosiding Seminar Nasional Darmajaya Media Farmasi Indonesia
Wulandari -, Wulandari
Program Studi Pendidikan Biologi, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Pasir Pengaraian
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Education Library & Information Science Medicine & Pharmacology Nursing Other

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Journal : Media Farmasi Indonesia

 1 
PEMANFAATAN EKSTRAK KHAMIR PHAFFIA RHODOZYMA SEBAGAI SUMBER KAROTENOID PADA PENGHAMBATAN TIROSINASE Rahardian, Muhammad Ryan Radix; -, Wulandari
Media Farmasi Indonesia Vol 12 No 1 (2017): Media Farmasi Indonesia
Publisher : STIFAR "YAYASAN PHARMASI SEMARANG"

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Abstract

Abstrak Ekstrak khamir Phaffia rhodozyma mengandung senyawa karotenoid berupa astaxhantin yang memiliki aktivitas sebagai penghambat tirosinase. Senyawa ini dapat menghambat tirosinase dalam mekanisme pembentukan melanin. Ekstrak khamir Phaffia rhodozyma diperoleh dengan cara menyari khamir dengan pelarut aseton dan dikeringkan menggunakan gas N2. Pengukuran aktivitas penghambatan tirosinase dilakukan dengan pengukuran dopakrom menggunakan spektrofotometer UV-Vis pada panjang gelombang 480,5 nm. Hasil penelitian menunjukkan bahwa nilai IC50  hidrokuinon lebih besar dari sampel Ekstrak karotenoid khamir Phaffia rhodozyma, yang mana masing-masing kontrol positif hidrokuinon memiliki nilai IC50 sebasar 90,34 µg/ml dan IC50 Ekstrak karotenoid khamir Phaffia rhodozyma sebasar 113,85 µg/ml.
ANTIBACTERIAL ACTIVITY TEST OF EXTRACT ETHANOL MANGO ARUM MANIS SKIN (MANGIFERA INDICA L) ON METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA -, Wulandari; Sulistyarini, Indah
Media Farmasi Indonesia Vol 13 No 2 (2018): Media Farmasi Indonesia
Publisher : STIFAR "YAYASAN PHARMASI SEMARANG"

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Methicillin resistant Staphylococcus aureus (MRSA) is a strain of Staphylococcus aureus that has been resistant to the antibiotic activity of the ?-lactam group, including the penicillinase-resistant penicillins (oxcacillin, methicillin, nafcillin, cloxacillin, dicloxacillin), cephalosporin and carbapenem. Therefore, it is necessary to consider the use of alternative antibiotics, especially through the utilization of Indonesian medicinal plants. One of them is the use of mango arum manis skin (Mangifera indica L). The skin of mango contains phenolic compounds, carotenoids, flavonoids and anthocyanins. This research aims to determine whether mango arum manis skin extract has the ability to inhibit the growth of MRSA bacteria. Mango cultivar arum manis skin extract is made by remacerationmethod with 70% ethanol solvent. Test of Antibacterial activity of mango arum manis skin extract was undertaken by diffusion method at 5%, 10%, 15%, 20%, 25% concentration with positive control of ciprofloxacin and negative control of dimethylsulfoxide (DMSO). The results showed that mango arum manis skin extract has the ability to inhibit the growth of MRSA bacteria.
Co-Authors Andin Irsadi Dahlia - Dwi Permatasari Indah Sulistyarini Indrajaya, Urip Laksono Trisnantoro Maria Suryani Pratomo, Panji Andhika Priyantini Widiyaningrum Rahardian, Muhammad Ryan Radix Rena Lestari, Rena Sri Ipnuwati Taufik -, Taufik Yudhistira Ardana, Yudhistira