Article Per Year (5 Year)
p-Index From 2019 - 2024
0.751
P-Index
This Author published in this journals
All Journal Proceedings of the International Conference on Applied Science and Health The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Donny Nauphar
Department Of Genetics, Faculty Of Medicine, Universitas Swadaya Gunung Jati, Cirebon, Jawa Barat,
Education Health Professions Medicine & Pharmacology Nursing Public Health

Published : 8 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 8 Documents
Search

 1 
THE EFFECT OF ORALLY ADMINISTERED CATFISH (Clarias gariepinus) SKIN AND MEAT ON EPITHELIALIZATION THICKNESS AND COLLAGEN DENSITY IN INCISION WOUND OF WISTAR RAT (Rattus norvegicus) Muhammad Irsyad Baihaqi; Muhammad Duddy Satrianugraha; Tiar M Pratamawati; Donny Nauphar
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Alternative medicine using animal is still rare whereas Indonesia have a lot of potential natural resources. Catfish is easily found animal in Indonesia and is common consumed as nutriment sources contains albumin, amino acid and fatty acids which plays an essential role of wound healing process. This study will determine effect of orally administered catfish (Clarias gariepinus) skin and meat on epithelialization thickness and collagen density in incision wound of white male rat (Rattus norvegicus). Methods: This experimental post-test only group design used 30 white male rat (Rattus norvegicus), that randomly divided into 4 tratment goup and one control group. The treatment group was given 12,5 mg/g W, 25 mg/g W, 37,5 mg/g W and 50 mg/g W dose of catfish (Clarias gariepinus) skin and meat flour, in the other hand the contol group were given aquades. Non-parametric analyses using Kruscall- Wallis and Mann Whitney test were used to compare epithelization thickness and collagen density. Result: The comparison results of epithelialization thickness between group C with TGI, C with TG2, C with TG3 and C with TG4 showed significant differences (p<0.05). TG4 was the thickest of all groups. Significant differences were also observed in collagen density result between C with TGI, C with TG2, C with TG3 and C with TG4 (p <0,05) TG4 showed the highest density of all groups. Conclusion: Catfish (Clarias gariepinus) skin and meat flour with 50 mg/200g W dose is effective for wound healing and increasing epithelial thickness and collagen density in Wistar rat (Rattus norvegicus) incision wounds. Keywords: Epithelial thickness, Collagen density, Wound, Catfish (Clarias gariepinus)
EFFECTIVENESS OF ORALLY USE TILAPIA (Oreochromis niloticus) ON WOUND LENGTH AND FIBROBLAST DENSITY ON INCISION WOUND OF WISTAR RAT (Rattus norvegicus) Sayyidah Vina Syauqia; A. Fariz Malvi Zamzam Zein; Tiar M. Pratamawati; Donny Nauphar
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: The incidence of a wound in Indonesia has increased from 7.5 percent in 2007 to 8.2 percent in 2013 according to Riskesdas. Wound care that widely used is povidone-iodine, but in case, it has a toxic effect on healthy cells around the wound. The albumin, amino acids, and fatty acids in Tilapia (Oreochromis niloticus) are the potential substances to accelerate the wound healing process. This study aims to investigate the efficacy of Tilapia (Oreochromis niloticus) on wound length and fibroblast density on the incision wound of Wistar rat (Rattus norvegicus). Methods: The study was conducted in the Food and Nutrition PAU Laboratory and Pathology Anatomy Laboratory of Universitas Gadjah Mada, Yogyakarta. This post-test only control group design experimental study used 30 male white rats that randomly divided into five groups, i.e. control group K, and treatment group P1, P2, P3 and P4 that were each given Tilapia with a dose of 12.5 mg/200gBW, 25 mg/200gBW, 37.5 mg/200gBW dan 50 mg/200gBW. The length of the wound was measured by a ruler each day. The rats were terminated on the 10th day to obtain wound tissue for H&E stained histopathological sections to observe fibroblast density. One Way ANOVA, Tamhane, Kruskal-Wallis and Mann Whitney tests were used to compare the wound length and fibroblasts density. Results: Incision wounds in this study showed the best wound healing on the 10th day. Based on the theory, on the 10th day, a proliferation and remodeling phase occurs. There is an effect of giving Tilapia (Oreochromis niloticus) orally at a different dose. Tilapia at dose 37.5mg/200gBW is more effective compared with the dose of 12.5mg/200gBW, 25mg/200gBW, and 50mg/200gBW to accelerate wound healing for wound length and fibroblast density in Wistar rat (Rattus norvegicus). Conclusion: Consuming Tilapia (Oreochromis niloticus) could be a new alternative for wound healing treatment. The antimicrobial ability of Tilapia should be analyzed. Keywords: wound healing, wound length, fibroblast density, Tilapia, Oreochromis niloticus
EFFECTIVENESS OF ORALLY USE CATFISH (Clarias gariepinus) SKIN AND MEAT ON WOUND LENGTH AND FIBROBLAST DENSITY IN INCISION WOUND OF WISTAR RAT (Rattus norvegicus) Sri Utami Fauziah; Risnandya Primanagara; Tiar M. Pratamawati; Donny Nauphar
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Treatment for wounds that are currently often given is use povidone-iodine. But, this antiseptics also kills fibroblast tissue which is useful for forming new tissue. One of the other ways to treatment for wounds is use catfish. The contents found in catfish (Clarias gariepinus) is albumin which is a globular protein that is useful in the formation of body tissues, such as postoperative wounds and burns. This study aims to determine the effect of skin and meat of catfish (Clarias gariepinus) on wound length and fibroblast density in incision wounds of Wistar rat (Rattus norvegicus). Methodology: This study is an experimental study with Post Test Only Control Group Design using Wistar rats which are divided into five groups. The control group (aquadest) and treatment groups 1, 2, 3 and 4 are given the skin and meat of catfish (Clarias gariepinus) orally at a dose of 12.5 mg / 200 g BW, 25 mg / 200 g BW, 37.5 mg / 200 g BW, and 50 mg / 200 g BW. After 10 days, the rats are killed to take the wound tissue for histological preparations to observe fibroblast density. Then, it is analyzed by ANOVA test or the alternative. Results: There is an effect of giving catfish skin and meat (Clarias gariepinus) orally at different dose. The administration of catfish skin and meat (Clarias gariepinus) at a dose of 37.5 mg / 200 g BW and 50 mg / 200 g BW is better than other doses assessed from wound length and fibroblast density in Wistar rat incision wounds (Rattus norvegicus). Conclusion: The use of catfish for wound healing can be applied. This method can reduce wound length and increase fibroblast density at certain doses. Keywords: Fibroblasts, incision wounds, catfish, Clarias gariepinus, wound healing
CHANGING COSMETIC BRANDS INCREASE RISK OF FREQUENCY AND DEGREE OF ACNE VULGARIS IN FEMALE UNDERGRADUATE STUDENTS Annida P Maharani; Witri Pratiwi; Donny Nauphar
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Acne vulgaris is a skin disease caused by chronic inflammation of the follicular pilosebacea marked by the presence of blackheads, papules, pustules, nodules, and cysts in place of healthy skin. One of the risk factors for Acne vulgaris is changing cosmetic brands which may contain comedogenic and acnegenic ingredients. The aim of this study is to find out the relationship of changing cosmetic brands and the prevalence of Acne vulgaris in female undergraduates. Methods: This was an observational study with cross sectional design. The subjects were 344 female undergraduates who used two out of four types of cosmetics, recruited by total sampling. Data were analyzed to see the relationship of changing cosmetic brands with the degree and the frequency of acne. Results: Based on Spearman correlation test, changing cosmetic brands has a strong positive correlation (r2= 0.762) with the degree of acne and a mild positive correlation (r2=0.461) with acne frequency. Chi-square test showed statistical significance (p<0.05) between changing cosmetic brands and the degree and frequency of acne. Subjects who frequently changes cosmetics has a 66 times higher risk of having bad acne (PR= 66.994; CI 95% = 32.099–139.320) and 8 times higher risk of having more frequent acne (PR= 8.432; CI 95% = 4.969-14.308) compared to subjects that do not frequently change cosmetics. Conclusion: Changing cosmetic brands increased the risk for both the degree of acne and the frequency of acne.
COMPARISON OF EFFECTIVENESS BETWEEN CELERY JUICE (Apium graveolens L.) AND 2% MICONAZOLE TOWARDS THE GROWTH OF Malassezia furfur Ronaa Hammada; Witri Pratiwi; Shofa Nur Fauzah; Donny Nauphar; Amanah Amanah
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Pityriasis versicolor is caused by the fungi Malassezia furfur with a worldwide prevalence of 50%, including tropical countries, second only to dermatitis in Indonesia. Pityriasis versicolor is difficult to treat and requires long-term treatment. The disease has high recurrence risk and may cause drug resistance. 2% Miconazole is known to have long-term side effects; therefore, alternative treatment is needed. Several studies suggested that celery (Apium graveolens L.) contains active substances with anti-fungal properties. This paper aims to investigate the comparison of effectiveness between celery juice and 2% Miconazole towards the growth of Malassezia furfur. Methods: This is an in-vitro experimental study with post-test only control group design. The subjects were split into 5 groups which were given celery juice in 10% DMSO with the concentration of 10%, 20%, 30%, 40%, and 50%. A negative control group was given only 10% DMSO and the positive control group was given 2% Miconazole. The data were then analyzed using Kruskall-Wallis followed by Mann-Whitney test. Results: The Kruskall-Wallis test showed all concentration of celery juice had antifungal effect with p=0.000 (p<0.05) and were effective in inhibiting the growth of Malassezia furfur. The Mann-Whitney test showed that the 50% celery concentration was as effective as 2% Miconazole in inhibiting the growth of Malassezia furfur (p=0.495). Conclusion: Celery juice (Apium graveolens L.) was effective in inhibiting the growth of Malassezia furfur with 50% concentration as the most effective concentration.
ANTENATAL CARE (ANC) VISIT FREQUENCY IN THE THIRD TRIMESTER AND PRETERM EVENTS IN PUSKESMAS PONDOH AND JUNTINYUAT IN INDRAMAYU REGENCY BETWEEN 2014-2016 Elinda Ameliana; Donny Nauphar; Ruri Eka Maryam
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: World Health Organization (WHO) estimates that 15 million babies are born preterm every year and this number continues to increase. Several risk factors for preterm are identified as mother’s lifestyle such as smoking, malnutrition, weight gain during pregnancy, and drug use or other factors such as socioeconomic status. In 2015, WHO reported more than 300.000 women died from pregnancy-related causes and 2.6 million babies were still born worldwide with half occurring during the third trimester. Antenatal Care (ANC) in the third semester aims to identify fetal position and identify complication during pregnancy and screen for pre-eclampsia, infection of the reproductive organs and urinary tract, and plan for delivery. The ANC in the third semester is crucial in keeping pregnant mother healthy throught pregnancy and delivery. Aim: To find out the relationship between third trimester Antenatal Care (ANC) visit frequency and preterm birth event at Puskesmas Pondoh and Juntinyuat in Indramayu regency between 2014-2016. Methods: This was observational analytic study with cross-sectional approach. The sampling technique in this research was done by total sampling with 100 respondens. Data were collected from maternal cohort book and control card of pregnant women. The data were analyzed using Chi-square test and Prevalence Ratio. Results: This study found that the proportion of pregnant mothers with insufficient third trimester ANC was 38% and the number of mothers delivering preterm baby was 32%. Statistical analysis showed that there was a statistical significance between third trimester ANC visit frequency and preterm labor with p=0,000 (p<0,05) and women with insufficient ANC visit have 40 times higher risk of preterm baby compared to mothers who has sufficient ANC visit (PR=40,60; CI95%=11.699-140.8862) in Puskesmas Pondoh and Juntinyuat Indramayu District 2014-2016. Conclusion: Having less than 4 ANC visit in the third trimester may increase the risk of delivering preterm babies. Pregnant women are advised to do ante natal care monthly of a minimum 4 times during the third trimester.
EFFECT OF PHYSICAL ACTIVITY AND FAST FOOD CONSUMPTION FREQUENCY ON OVERWEIGHT LEVEL AMONG HIGH SCHOOL ADOLESCENT Lita Harlianti; Witri Pratiwi; Donny Nauphar; Eni Suhaeni
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Obesity was believed to be one of the risk factors of degenerative diseases, such as diabetes mellitus, hypertension, and coronary heart disease. Obesity occurred gradually that started with overweight. Risk factors for overweight are lack of physical activity, and consumption of high caloric fatty food which may cause accumulation of fats inside the body. This research aims to examine the effect of physical activity and fast food consumption frequency on overweight level among high school adolescent in Cirebon. Methods: It was a cross-sectional study conducted among 262 high school students aged 15-17 years using stratified random sampling. Results: The result based on Spearman correlation test showed negative correlation between physical activity and overweight level with p= 0,001 (p< 0,05) and correlation coefficient of -0,627. There was positive correlation between consumption fast food frequency with overweight with p=0,037 (p=0,05) and correlation coefficient of 0,423. Conclusions: Physical activity and fast food consumption frequency have effects on overweight level in high school adolescent in Cirebon.
The Association Between the Pattern of Electronic Cigarette Smoking and Gastroesophageal Reflux Ahmad Fariz Malvi Zamzam Zein; Donny Nauphar; Uswatun Khasanah; Tiar M Pratamawati; Rama S Brajawikalpa; Eka Ayuningtyas; Alif Hamzah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 1 (2021): VOLUME 22, NUMBER 1, April 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (433.581 KB) | DOI: 10.24871/221202116-20

Abstract

Background: This study was aimed to investigate the proportion of gastroesophageal reflux (GER) among electronic cigarette (e-cig) smokers and its association with the pattern of e-cig smoking.Method: This cross-sectional study underwent among e-cig smokers community in Cirebon City, Jawa Barat, ranged from March to August 2020. Subjects were enrolled through consecutive sampling method. The data collection used survey containing the pattern of e-cig smoking and GER. The pattern of e-cig smoking included the duration of e-cig smoking and the amount of e-cig smoking. Gastroesophageal reflux consisted of GER-related symptoms (heartburn, regurgitation, and nocturnal symptom) and gastroesophageal reflux disease (GERD). GERD was defined as GERD questionnaire score cut-off 8. Data analysis used chi square test. This study has been approved by The Medical Research Ethics Committee, Faculty of Medicine, Universitas Swadaya Gunung Jati.Results: There were 273 respondents in this study. The proportion of heartburn was 6.6%, 10.3% for regurgitation, 3.7% for nocturnal symptom, and 5.5% for GERD. There was no association between duration of e-cig smoking and heartburn (p 0.681), regurgitation (p 0.568), nocturnal symptom (p 0.764), and GERD (p 0.113). There was no association between amount of e-cig smoking and heartburn (p 0.062), regurgitation (p 0.770), nocturnal symptom (p 0.985), and GERD (p 0.605).Conclusion: There was relatively low proportion of GER among e-cig smokers. There was no association between the pattern of e-cig smoking and GER in this study.
Co-Authors Ahmad Fariz Malvi Z Zein Alif Hamzah Amanah Amanah Annida P Maharani Eka Ayuningtyas Elinda Ameliana Eni Suhaeni Lita Harlianti Muhammad Irsyad Baihaqi Rama S Brajawikalpa Risnandya Primanagara Ronaa Hammada Ruri Eka Maryam Mulyaningsih Satrianugraha, Muhammad Duddy Sayyidah Vina Syauqia Shofa Nur Fauzah Sri Utami Fauziah Tiar Masykuroh Pratamawati Uswatun Khasanah Witri Pratiwi