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PENGENALAN ATRAKTAN MOSQUITO TRAP HERBAL DALAM PENCEGAHAN PENYAKIT DEMAM BERDARAH DENGUE (DBD) DI DUSUN 2, PERUMAHAN INDOGRIYA, KLANGENAN, KABUPATEN CIREBON Dadan Ramadhan Apriyanto; Sri Marfuati; Ruri Eka Maryam Mulyaningsih
JURNAL PENGABDIAN KEPADA MASYARAKAT Vol 26, No 2 (2020): APRIL - JUNI
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpkm.v26i2.17218

Penyakit Demam Berdarah Dengue (DBD) merupakan permasalahan kesehatan yang serius di Kabupaten Cirebon, dengan 846 jumlah kasus terjangkit penyakit DBD pada tahun 2019 yang meningkat dari tahun sebelumnya. Dusun 2, RW.006, Perumahan Indogriya, Desa Klangenan, Kecamatan Klangenan, Kabupaten Cirebon merupakan salah satu wilayah yang endemis terjangkit Demam Berdarah Dengue (DBD). Program pengabdian kepada masyarakat ini dilakukan sebagai upaya menaggulangi penyakit demam berdarah Dengue (DBD) melalui pemanfaatan herbal diterapkan dengan pembuatan produk atraktan mosquito trap yang bersal dari dari tanaman obat. Pengadaan produk dilakukan oleh warga mitra dengan pendampingan tim pelaksana melibatkan stakeholder. Metode yang digunakan adalah pemberian penyuluhan pencegahan DBD dan pelatihan pembuatan atraktan mosquito trap herbal dalam pencegahan DBD secara langsung secara interaktif. Hasil yang diperoleh dari kegiatan ini adanya antusias dari warga Perumahan Indogriya dalam mengimplementasikan mosquito trap dari bahan alami dan ingin mebudidayakan beberapa tanaman yang sebelumnya delum diketahui manfaatnya untuk pencegahan DBD seperti daun jenu dan juga daun kecubung.Kata kunci: Demam Berdarah Dengue; atraktan mosquito trap herbal; Klangenan.AbstractDengue Hemorrhagic Fever (DHF) is a serious health problem in Kabupaten Cirebon with the number of DHF cases about 846 in 2019. Dusun 2, RW.006, Indogriya Regency, Klangenan Village is one area endemic with Dengue Hemorrhagic Fever (DHF). This program is carried out as an effort to overcome dengue fever (DHF) through the use of herbs that are applied by making attractant mosquito trap products derived from medicinal plants. The product procurement is carried out by partner citizens with the assistance of the stakeholder involvement implementation team. The method used was extension assistance about DHF and training on making herbal mosquito traps in DHF that was sponsored directly interactively. The results obtained from this activity were the enthusiasm of the residents of Indogriya Housing in implementing mosquito traps from natural materials and wanted to cultivate some plants that had not previously been known for the benefits of DHF prevention such as jenu and kecubung leaves.Keywords: Dengue Hemorrhagic Fever; attractant mosquito trap herbs; Klangenan.

HUBUNGAN PENGGUNAAN KB HORMONAL DENGAN KEJADIAN OBESITAS PADA WANITA USIA SUBUR DI WILAYAH KERJA PUSKESMAS KEJAKSAN KOTA CIREBON Ruri Eka Maryam Mulyaningsih; Faqih Bawazir Sudrajat
Tunas Medika Jurnal Kedokteran & Kesehatan Vol 3, No 2 (2016): Tunas Medika Jurnal Kedokteran & Kesehatan
Publisher : Tunas Medika Jurnal Kedokteran & Kesehatan

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ABSTRAK Latar Belakang:Program KB mempunyai tujuan ganda, yaitu menurunkan tingkat kelahiran dan mewujudkan normakeluarga kecil bahagia dan sejahtera. Namun tidak dapat dipungkiri timbulnya efek lain daripenggunaan alat kontrasepsi khususnya pemakaian alat kontrasepsi hormonal, hal ini dapatmenimbulkan berbagai efek samping diantaranya adalah perubahan berat-badan akseptor jika dibiarkan akan menimbulkan obesitas lama kelamaan, dimana efek tersebut banyak dikeluhkan oleh akseptor. Tujuan:menganalisis hubungan penggunaan KB hormonal dengan kejadian obesitas pada wanita usia subur di Wilayah Kerja Puskesmas Kejaksan Kota Cirebon. Metode:Jenis penelitian yang digunakan adalah penelitian observasi dengan desain Cross sectional, populasi dalam penelitian ini adalah Wanita Usia Subur yang aktif sebagai akseptor KB hormonal di Kota Cirebon dengan jumlah responden sebanyak 96 dan ditentukan dengan cara simple random sampling. Hasil: responden mengalami obesitas sebanyak 23 responden dengan presentase 24%, sedangkan responden yang tidak mengalami obesitas sebanyak 73 dengan presentase sebanyak 76%. responden menggunakan kontrasepsi/ KB hormonal jenis suntik/ injeksi sebanyak 61 responden dengan presentase 63,5%, sedangkan responden yang menggunakan kontrasepsi/ KB hormonal jenis pil sebanyak 25 responden dengan presentase 26%, dan reponden yang menggunakan kontrasepsi/ KB hormonal jenis implant sebanyak 10 responden dengan presentase 10, 4%.Berdasarkan besarnya nilai signifikasi (P.value) yang besarnya 0,897 maka Ho (tidak terdapat hubungan) di terima, dan nilai correlation sebesar -0,013 dimana jika nilai correlation korelasi 0,00 sampai 0,20 maka tidak ada korelasi. Simpulan: Tidak terdapat hubungan antara penggunaan KB hormonal pada wanita usia subur terhadap kejadian obesitas di wilayah kerja Puskesmas Kejaksan Kota Cirebon Kata Kunci:KB hormonal, Obesitas ABSTRACT Background: Program KB or familly planing program have two purpose which are reduce birth rate andimprove famly living standards. however, can not be denied there are side effect in the usage of contraception especially hormonal contraception, among thouse effect are changes in body weigh, which many user complain.this problem are intresting to study. Aim: to analize the connection between hormonal contraception usege with the prevalence of obesity in women of childbearing age within Puskesmas Kejaksan Kota Cirebon working area. Method: Observational with cross sectinal desain study were conducted towomen of childbearing ageas hormonal contraception user in cirebon city. 96 samples were observed and was taken using simpel random sampling. Result: 23 or 24% responden were obese, while 73 or 63,5% were not. while 61 respondent were using injection type hormonal contraception, 25 were using pil type hormonal contraception, and 10 respondent uses implant type hormonal contraception. The resesult shows no statisticl significancy among variabels with p value of 0,897. While there were no correlation can be establish between the variables(-0,013). Conclusion: there were no corelation between usage of hormonal contraception and obesity within Puskesmas Kejaksan Kota Cirebon working area. (p=0,897>0,05) Keywords:Hormonal contraception, Obesity

Efek Pemberian Ekstrak Daun Tempuyung (Sonchus arvensis L.) Terhadap Penurunan Kadar Asam Urat Pada Tikus Wistar Putih (Rattus norvegicus) Jantan Hiperurisemia Cindyyani Eka Putri; Rama Samara Brajawikalpa; Ruri Eka Maryam Mulyaningsih
Tunas Medika Jurnal Kedokteran & Kesehatan Vol 5, No 1 (2019): Tunas Medika Jurnal Kedokteran & Kesehatan
Publisher : Tunas Medika Jurnal Kedokteran & Kesehatan

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Latar Belakang: Hiperurisemia adalah keadaan terjadinya peningkatan kadar asam urat darah di atas normal dan termasuk kedalam salah satu penyakit tidak menular yang angka kejadiannya masih tinggi mencapai 20% di dunia. Daun tempuyung (Sonchus arvensis L.) mengandung flavonoid sebagai penurun kadar asam urat melalui penghambatan kerja enzim xantin oksidase. Tujuan: Penelitian ini ditujukan untuk mengetahui dosis efektif ekstrak daun tempuyung terhadap penurunan kadar asam urat pada tikus wistar hiperurisemia. Metode: Metode Penelitian ini adalah penelitian eksperimental dengan pre-post test with control group design. Sampel menggunakan 30 ekor tikus wistar secara random dikelompokkan kedalam 5 kelompok secara Simple Random sampling. 2 kelompok kontrol (K- diberi pakan standar + akuades dan K+ diberi pakan tinggi purin + akuades) dan 3 kelompok perlakuan (pakan tinggi purin + esktrak daun tempuyung dosis 70 mg/200gBB, 75 mg/200gBB, dan 80 mg/200gBB). Periksa kadar asam urat pada 30 ekor tikus wistar , darah tikus wistar didapatkan melalui sinus orbitalis yang sudah dibius terlebih dahulu dengan menggunakan eter. Dan periksa kadar asam urat diukur dengan metode TBHBA. Hasil: Perbedaan bermakna (p<0,05) kadar asam urat sebelum dan sesudah perlakuan hanya ditunjukkan oleh kelompok perlakuan. Dengan rerata penurunan, Kelompok P1 2.5334 mg/dL, Kelompok P2 5.3993 mg/dL Kelompok P3 5.8599 mg/dL. Simpulan: Ekstrak daun tempuyung dosis 80 mg/gBB paling efektif menurunkan kadar asam urat darah.Kata Kunci: Daun Tempuyung, Asam Urat, hiperurisemia, tikus wistar, xantin oksidaseABSTRACTIntroduction: Hyperuricemia is a case of the increase of uric acid above normal levels of blood and includes to the one of non-communicable diseases which the number of events is still high, reaching 20% in the world. Tempuyung leaf (Sonchus arvensis L.) contains of flavonoids which has a benefit for decrease uric acid through the inhibition of enzyme xanthine oxidase action. Aim: This study aimed to knows the effective dose of tempuyung leaf extract to decrease uric acid levels in wistar rats hyperuricemic. Methods: This research methodology is Experimental research with Pre-post test with control group design. The samples were 30 wistar rats. Rats was divided into 2 control groups (K- are given standar feed+ aquadet and K+ are given high purine feed + aquadest ) and 3 treatment groups (high purine feed + extract tempuyung leaves dose 70 mg/200gBW, 75 mg/200gBW, 80 mg/200gBW). Check uric acid levels in 30 wistar rats, the blood of wistar rats is obtained through the orbital sinus which has been anesthetized first using ether. And check the uric acid level is measured by the TBHBA method. Resulsts: Significant differences (p <0.05) uric acid levels before and after treatment were only indicated by the treatment group. With a mean reduction in P1 2.5334 mg/dL, P2 group 5.3993 mg/dL, P3 group 5.8599 mg/dL. Conclusions: Tempuyung leaves extract with dose 80 mg/200gBW is most effective for reducing the uric acid level in blood.Keywords: Tempuyung leaves, Uric Acid, Hyperuricemic, Wistar rats, Xanthine oxidase.

UJI ANTIBAKTERI FRAKSI N-HEKSANA, ETIL ASETAT, DAN AIR DAUN SALAM (SYZYGIUM POLYANTHUM (WIGHT) WALP.) TERHADAP SALMONELLA TYPHI Kamila Juliana Fatonah; Ruri Eka Maryam; Dadan Ramadhan Apriyanto
Tunas Medika Jurnal Kedokteran & Kesehatan Vol 7, No 2 (2021): TUNAS MEDIKA JURNAL KEDOKTERAN & KESEHATAN
Publisher : Tunas Medika Jurnal Kedokteran & Kesehatan

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Latar Belakang: Salmonella typhi merupakan bakteri penyebab demam tifoid. Banyak yang melaporkan terjadinya resistensi antibiotik terhadap S. typhi. Oleh karena itu dibutuhkan alternatif pengobatan. Beberapa penelitian mengatakan daun salam mengandung zat metabolit sekunder seperti alkaloid, flavonoid, saponin dan tanin yang berfungsi sebagai antibakteri. Tujuan: Mengetahui efektivitas antibakteri fraksi n-heksana, fraksi etil asetat dan fraksi air dari daun salam terhadap pertumbuhan Salmonella typhi. Metode: Penelitian yang dilakukan bersifat eksperimental laboratorium dengan rancangan penelitian post-test only control group design. Penelitian ini menggunakan 11 kelompok, yaitu 2 kelompok kontrol dan 9 kelompok perlakuan. Kelompok perlakuan terdiri dari fraksi n-heksana, etil asetat, dan air dari daun salam konsentrasi 5 mg/ml, 25 mg/ml, 50 mg/ml. Kelompok kontrol yaitu kontrol positif (K(+)) dengan Cefixime dan kontrol negatif (K(-)) yaitu Dimetil Sulfoksida (DMSO) 10%. Data diuji menggunakan uji One Way Anova dilanjutkan dengan uji Post Hoc Tamhane. Hasil: Pada uji One Way Anova terdapat perbedaan yang signifikan (p-value < 0,001), terhadap pemberian perlakuan fraksi n-heksana, fraksi etil asetat dan fraksi air daun salam. Didapat rerata terbesar yaitu pada fraksi air daun salam konsentrasi 50 mg/ml (12 mm). Dilanjutkan dengan uji Pos hoc Tamhane untuk mengetahui perbedaan antar kelompok, didapatkan perbedaan daya hambat pada masing-masing konsentrasi. Simpulan: Fraksi n-heksana, fraksi etil asetat dan fraksi air dari daun salam (Syzygium polyanthum (Wight)Walp.) memiliki efektivitas antibakteri terhadap Salmonella typhi.Kata Kunci: Daun salam, Fraksi, Salmonella typhi, Syzygium polyanthum (Wight)Walp.)

THE EFFECT OF LEMON JUICE (Citrus limon) IN LIVER HISTOPATHOLOGIC APPEARANCE OF MALE MICE (Mus musculus L.) EXPOSED BY MONOSODIUM GLUTAMATE (MSG) Dela Destiani Aji; Ruri Eka Maryam Mulyaningsih; Ahmad Fariz MZZ
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Excessive consumption of MSG can cause the formation of free radicals in the body. Continuous use of MSG will cause free radical accumulation and oxidative stress in the liver. An antioxidant is one of the substances that has an ability to eliminate free radicals and protect the liver from oxidative stress. Lemon is a fruit that has benefits as a natural antioxidant. This study aims to determine the effect of administering lemon juice on the histopathological appearance of the liverexposed by MSG. Methodology: This post-test only control group design experimental study used 30 male white mice which were randomly divided into five groups: NC group, C(-) group, D1 group, D2 group, and D3 group. After 7 days of adaptation and randomized grouping, the mice were treated differently based on their group. All groups, except the NC group, were exposed to 4mg/gBW dose of MSG orally for 14 days. On the 15th day, MSG exposure was stopped and after that D1 group, D2 group, and D3 group were given lemon juice with a dose of each group 3.33ml/kgBW, 6.67 ml/kgBW, 13.33 ml/kgBW. The lemon juice was given once a day for 14 days using the gastric sonde. Histopathology examination was analyzed by pathologist in Gunung Jati Hospital, Cirebon, Indonesia. Results: Significant differences of liver histopathology were obtained between the normal control group with the dose 3 group (p = 0.005), the normal control group with the dose 2 group (p = 0.019), the normal control group with the dose group (p = 0.019) and between the negative control groups with dose 3 group (p = 0.027). Dose 3 group has higher liver damage compared to a normal control group and negative control group characterized by the form of parenchymatous degeneration. Conclusion: Lemon juice has a negative effect on the histopathology appearance of male white mice’s (Mus musculus L.) liver exposed by monosodium glutamate (MSG). Further studies are needed to validate the effect of the active compound and toxicity of lemon juice and to reveal the precise mechanisms on how lemon juice affects the hepatocytes. Keywords: Monosodium Glutamate (MSG), Citrus lemon, Histopathology Liver

CORRELATION BETWEEN ANXIETY LEVEL AND SELF DIRECTED LEARNING READINESS (SDLR) WITH STUDENT PEFORMANCE IN PROBLEM BASED LEARNING (PBL) Nita Safitri; Uswatun Khasanah; Ruri Eka Maryam Mulyaningsih
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: The pattern of medical education in Indonesia has changed from teacher-centered learning to student-centered learning. This change has an impact on methods, learning activities, and learning achievements of medical students. Problem Based Learning (PBL) is one of the main learning methods used in the faculty of medicine. PBL is a learning method that requires students to play an active role and facilitate collaborative learning. Due to the change of learning method, new medical students experience a lot of stress from in doing Problem Based Learning such as anxiety and may affect their PBL results as can be evaluated using Self-Directed Learning Readiness (SDLR). There are very few studies found to date investigating this phenomenon. Aims: This research aims to see the correlation between anxiety level and SDLR with student’s performance participating in first-year PBL in the Musculoskeletal and Locomotory System block in the faculty of medicine Universitas Swadaya Gunung Jati Cirebon. Methods: This is a cross-sectional observational study with total sampling. The samples were recruited from 167 first-year 2018 intake students of the faculty of medicine Universitas Swadaya Gunung Jati. Zung Self Rating Anxiety Scale questionnaire is used to measure anxiety levels and the SDLR questionnaire is used to measure Self Directed Learning Readiness (SDLR). Results: The Spearman test showed a medium negative correlation value of -0.49 (p>0.05) for the level of anxiety. It means that there is no significant effect of anxiety on the PBL performance. In addition, it shows a weak positive correlation value of 0.196 (p <0.05) for SDLR (self-directed learning readiness) showing a significant influence on PBL performance. Conclusions: The level of anxiety does not significantly influence PBL performance while SDLR has a significant effect on PBL performance. Keywords: Anxiety Level, Self-Directed Learning Readiness, Problem Based Learning.

INHIBITORY OF SOURSOP LEAVES (Annona muricata L.) EXTRACT AGAINST Malassezia furfur GROWTH Rike Rizqilah; Dadan Ramadhan Apriyanto; Ruri Eka Maryam Mulyaningsih
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Malassezia furfur in certain conditions can turn into a pathological phase, from the yeast phase to the mycelia phase that attacks the stratum corneum. Malassezia furfur is one of the causes of Pityriasis versicolor. The prevalence of pityriasis versicolor in Indonesia is quite high at around 40- 50%. Several studies suggested that soursop leaves (Annona muricata L.) contains active substances with anti-fungal properties. This study aims to determine the inhibition of soursop leaves (Annonamuricata L.) extract against the growth of Malassezia furfur. Methods: This study was an experimental study with Post-test Only Control Group Design. Malassezia furfur fungi is used as subject in this study and ethanol extract of soursop leaves as a natural antifungal against Malassezia furfur. The concentrations of extract tested were 100%, 80%, 60%, 30%. Miconazole 2% was used as a positive control while DMSO 10% was used a negative one. The result of the study was analyzed by descriptive analysis which showed by increasing average diameter ofantifungal. Results: The results showed that soursop leaves (Annona muricata L.) extract had inhibitory effect on the growth of Malassezia furfur fungi at 100% concentration of 2.50 mm, 80% at 1.50 mm, 60% at 0.47 mm, 30% concentration at 0.25 mm and positive control of 14.50 mm. While as negative control, no inhibition zones were formed on SDA media. Conclusion: Soursop leaves (Annona muricata L.) extract can inhibit the growth of Malassezia furfur, but the formed inhibition zone is weak. Further research is needed to found the best type of antifungal metabolites to maximize antifungal effects. Keywords: Soursop leaves extract, Annona muricata L. , Malassezia furfur

THE CORRELATION OF EDUCATION AND SOCIAL ECONOMIC LEVELS WITH ANTIBIOTIC SELF-MEDICATION IN THE COMMUNITY OF CIREBON Tridaya Putri Handayani; Muhammad Duddy Satrianugraha; Witri Witri Pratiwi; Ruri Eka Maryam Mulyaningsih
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: People in developing countries, like Indonesia, often conduct self-medication. One of the most common drugs used in self-medication is antibiotics. Antibiotics should be used with caution since it can cause antibiotic resistance and possible unwanted side effects of the drug. There are several factors that influence self-medication behavior such as education and socio-economic levels. This research aims to find the correlation between education and social economic levels with antibiotic selfmedication in the community of Cirebon. Method: This study was an analytical survey with cross-sectional method. This study was conducted from December 2018 to February 2019. A total of 300 respondents were recruited as samples using consecutive sampling technique. The respondents were recruited from 5 different pharmacies from each sub-district in Cirebon City and a validated questionnaire were used to obtain data. The collected data are analyzed using the Spearman correlation test. Results: The results of this study show that there was a significant but weak positive correlation of education level (r=0.224, p=0.001) and socio-economic (r=0.210, p=0.001) with self-medication using antibiotics. Conclusion: There is a significant positive correlation between education and socio-economic levels with antibiotic self-medication. Keywords: self-medication, education level, socio-economic level

ANTENATAL CARE (ANC) VISIT FREQUENCY IN THE THIRD TRIMESTER AND PRETERM EVENTS IN PUSKESMAS PONDOH AND JUNTINYUAT IN INDRAMAYU REGENCY BETWEEN 2014-2016 Elinda Ameliana; Donny Nauphar; Ruri Eka Maryam
Proceedings of the International Conference on Applied Science and Health No. 3 (2018)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: World Health Organization (WHO) estimates that 15 million babies are born preterm every year and this number continues to increase. Several risk factors for preterm are identified as mother’s lifestyle such as smoking, malnutrition, weight gain during pregnancy, and drug use or other factors such as socioeconomic status. In 2015, WHO reported more than 300.000 women died from pregnancy-related causes and 2.6 million babies were still born worldwide with half occurring during the third trimester. Antenatal Care (ANC) in the third semester aims to identify fetal position and identify complication during pregnancy and screen for pre-eclampsia, infection of the reproductive organs and urinary tract, and plan for delivery. The ANC in the third semester is crucial in keeping pregnant mother healthy throught pregnancy and delivery. Aim: To find out the relationship between third trimester Antenatal Care (ANC) visit frequency and preterm birth event at Puskesmas Pondoh and Juntinyuat in Indramayu regency between 2014-2016. Methods: This was observational analytic study with cross-sectional approach. The sampling technique in this research was done by total sampling with 100 respondens. Data were collected from maternal cohort book and control card of pregnant women. The data were analyzed using Chi-square test and Prevalence Ratio. Results: This study found that the proportion of pregnant mothers with insufficient third trimester ANC was 38% and the number of mothers delivering preterm baby was 32%. Statistical analysis showed that there was a statistical significance between third trimester ANC visit frequency and preterm labor with p=0,000 (p<0,05) and women with insufficient ANC visit have 40 times higher risk of preterm baby compared to mothers who has sufficient ANC visit (PR=40,60; CI95%=11.699-140.8862) in Puskesmas Pondoh and Juntinyuat Indramayu District 2014-2016. Conclusion: Having less than 4 ANC visit in the third trimester may increase the risk of delivering preterm babies. Pregnant women are advised to do ante natal care monthly of a minimum 4 times during the third trimester.

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