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All Journal Majalah Kedokteran Bandung Medical Journal of Indonesia Jurnal Farmasi Klinik Indonesia Majalah Kedokteran Nusantara The Journal Of Medical School Sumatera Medical Journal AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh
dharma Lindarto, dharma
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Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Sumatera Medical Journal

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Chronic Effect Various Type of Exercises to Fasting Blood Glucose and Insulin Resistance Machrina, Yetty; Purba, Ambrocious; Lindarto, Dharma; Daulay, Milahayati
Sumatera Medical Journal Vol. 2 No. 2 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.253 KB) | DOI: 10.32734/sumej.v2i2.1063

Abstract

Exercise is non-pharmacological management for Diabetes Mellitus (DM) type-2. Previous study found that both eerobic and interval training improved insulin resistance. The aim of this study was to analyze the chronic effect various type of exercises to fasting blood glucose (FBG) and insulin resistance in DM type-2 model rats. It was an experimental study, twenty male Wistar rats, age 8 weeks, weight 150-180 gram as the object. Rats were given high fed diet for 4 weeks then injected streptozocin dose 30 mg/kgBB in citrate buffer pH 4.5 i.p, and 45 mg/kgBB at the following week. Groups were divided into i.e moderate continous training (MCT), severe continous training (SCT), slow interval training (SIT), and fast interval training (FIT). All groups were treated with ran on the treadmill three times a week for 8 weeks. Fasting blood glucose and fasting insulin were checked before and after intervention. Insulin resistance was determined by calculating HOMA-IR. Data analized with paired t-test (p<0,05). The results shown that all group significantly decreased fasting blood glucose and insulin resistance (p <0,05) after eight weeks exercise except insulin resistance in MCT group. Fasting blood glucose and insulin resistence post-test was found lowest in SIT groups in this study. In conclucions chronic effect of aerobic continous and aerobic interval in various intensity can decrease fasting blood glucose and insulin resistance in DM type-2 rat model. Slow interval training was the best exercise model to decrease insulin resistance.
Co-Authors Achmad Rudijanto Dasopang, Eva S. Daulay, Milahayati Kumala, Poppy Purba, Ambrocious Puteri, Happy Helene Sulung Ratna Akbari Ganie, Ratna Akbari Sahputri, Juwita Santi Syafril, Santi Siahaan, Billy Stinggo Tjokorda Gde Dalem Pemayun Urip Harahap Wismandari Wisnu Yetty Machrina Yulindaa, Wina