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Standardization Methods for the Determination of Curcumin in Turmeric and Its Anticancer Activities : A Review Imel Ramelia Hudaya; Vina Luthfiana Hasna; Febi Febriani Hasanah; Khamairah Azzahrawaani Hermawan; Vriezka Mierza
Jurnal EduHealth Vol. 14 No. 01 (2023): Jurnal eduHealth, Periode Januari-Maret, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.465 KB)

Abstract

Cancer is one of the deadliest diseases in the world. Indonesia is a country with cancer rates that ranks 8th in Southeast Asia. Cancer that has the highest number of sufferers in Indonesian men is lung cancer, as much as 19.4 per 100,000 population, with an average death rate of 10.9 per 100,000. Meanwhile, for women, breast cancer is the highest cancer incidence rate, which is 42.1 per 100,000 population, with an average death rate of 17 per 100,000 population. Although chemotherapy remains a highly efficient way to treat cancer, it is the drawbacks related to its side effects that are often feared. Natural products such as plants are more beneficial for improving treatment results because they are safe and can minimize side effects on healthy cells. Herbal plants that are often associated with anticancer drugs are turmeric. Currently, several standardized methods have been developed to analyze curcumin in turmeric, and from these methods, there are advantages and disadvantages of each method. Therefore, selecting the analytical method is very important to get better results.
Isolasi Senyawa Metabolit Sekunder pada Beberapa Hewan Bahari Rika Valensia; Hajar Hartati; Khamairah Azzahrawaani Hermawan
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 2 No 1 (2021): PharmaCine : Journal of Pharmacy, Medical and Health Science
Publisher : Program Studi Farmasi Fakultas Ilmu Kesehatan Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v2i1.5576

Abstract

Biota laut merupakan suatu bahan alam baik hewan maupun tumbuhan yang biasanya tersebar di lautan dan memiliki banyak manfaat bagi kehidupan salah satunya dibidang kesehatan karena mengandung senyawa metabolit yang memilki efek farmakologi. Tujuan review artikel ini dibuat untuk mengetahui senyawa metabolit sekunder pada beberapa hewan bahari melalui proses isolasi sehingga dapat dimanfaatkan dalam bidang kesehatan. Metode review artikel ini adalah tinjauan literatur yang bersumber pada pencarian database seperti google scholar. Hasil penelitian yang dilakukan pada beberapa hewan bahari melalui serangkaian proses isolasi menunjukan bahwa senyawa alkaloid dapat ditemukan pada teripang pasir Holothuria scabra, spons Stylotella sp., dan karang laut Sarcophyton sp,, sedangkan untuk senyawa terpenoid bisa didapatkan pada spons Petrosia sp.