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Analisa Biaya Terapi Antibiotik Ceftriakson pada Pasien Infeksi Demam Tifoid Rawat Inap Rumah Sakit Tahun 2020 Anggi Restyana; Fendy Prasetyawan; Yuneka Saristiana; Nisa Azzahra Dentika; Nina Nur Jannah
Jurnal Ilmiah Universitas Batanghari Jambi Vol 22, No 3 (2022): Oktober
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v22i3.2286

Abstract

Typhoid fever is an infection of the digestive tract caused by Salmonella typhi (Eberthella typhosa) results in inflammation of the small intestine and the lumen of the digestive tract. Ceftriaxone antibiotic treatment costs for hospitalized typhoid illness patients in 2020 were the focus of this investigation. A cross-sectional strategy was used in the study design, which was based on the collecting of medical records and funding records. From October 2021 to December 2021, the trial was conducted at Hospital X. A sample of typhoid patients admitted to the inpatient ward of Hospital X, with BPJS payment status, was used for this study's data collection. For typhoid patients at Jombang Regency X Hospital, the average cost of ceftriaxone antibiotics totaled IDR 1,502,796 per patient.
EVALUASI RASIONALITAS TERAPI PADA PASIEN OSTEOARTRITIS DI RSUD GAMBIRAN KOTA KEDIRI Tsamrotul Ilmi; Fitrani Khansa; Anggi Restyana; Fendy Prasetyawan
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol 4, No 1 (2022): Vol. 4 No.1 Desember 2022
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v4i1.3684

Abstract

Osteoartritis merupakan  penyakit sendi degeneratif yang memerlukan terapi jangka panjang sehingga pola terapi yang tepat dan rasional sangat dibutuhkan.   Penelitian ini bertujuan untuk mengetahui rasionalitas pengobatan pada osteoartritis di RSUD Gambiran Kota Kediri tahun 2019-2022. Jenis penelitian adalah observasional bersifat diskriptif analitik. Pengumpulan data dilakukan secara retrospektif menggunakan rekam medis. Teknik pengambilan sampel dengan metode purposive sampling didapatkan sampel berjumlah 34 pasien yang memenuhi kriteria inklusi dan eksklusi dengan rincian 27 pasien rawat inap dan 7 pasien rawat jalan. Pasien osteoartritis rawat inap sebagian besar mendapatkan tindakan pembedahan. Hasil penelitian didapatkan bahwa pasien osteoartritis terbanyak berjenis kelamin perempuan 73,5% dan rentang usia 56-65 tahun 55,9%. Terapi obat digunakan yaitu anbacim inj (cefuroxime) sebesar 19,1%, santagesik inj (metamizole) sebesar14,5% dan ketorolac inj sebesar 11,8%. Berdasarkan evaluasi rasionalitas terapi obat diperoleh hasil tepat diagnosis 100%, tepat indikasi 100%, tepat pasien 88,2%, tepat obat 100%, tepat dosis 82,4%, tepat cara pemberian 100%, tepat lama pemberian 91,1%, dan tepat interval waktu pemberian 76,5%.
EVALUASI RASIONALITAS TERAPI PADA PASIEN OSTEOARTRITIS DI RSUD GAMBIRAN KOTA KEDIRI Tsamrotul Ilmi; Fitrani Khansa; Anggi Restyana; Fendy Prasetyawan
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 4 No. 1 (2022): Vol. 4 No.1 Desember 2022
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v4i1.3684

Abstract

Osteoartritis merupakan  penyakit sendi degeneratif yang memerlukan terapi jangka panjang sehingga pola terapi yang tepat dan rasional sangat dibutuhkan.   Penelitian ini bertujuan untuk mengetahui rasionalitas pengobatan pada osteoartritis di RSUD Gambiran Kota Kediri tahun 2019-2022. Jenis penelitian adalah observasional bersifat diskriptif analitik. Pengumpulan data dilakukan secara retrospektif menggunakan rekam medis. Teknik pengambilan sampel dengan metode purposive sampling didapatkan sampel berjumlah 34 pasien yang memenuhi kriteria inklusi dan eksklusi dengan rincian 27 pasien rawat inap dan 7 pasien rawat jalan. Pasien osteoartritis rawat inap sebagian besar mendapatkan tindakan pembedahan. Hasil penelitian didapatkan bahwa pasien osteoartritis terbanyak berjenis kelamin perempuan 73,5% dan rentang usia 56-65 tahun 55,9%. Terapi obat digunakan yaitu anbacim inj (cefuroxime) sebesar 19,1%, santagesik inj (metamizole) sebesar14,5% dan ketorolac inj sebesar 11,8%. Berdasarkan evaluasi rasionalitas terapi obat diperoleh hasil tepat diagnosis 100%, tepat indikasi 100%, tepat pasien 88,2%, tepat obat 100%, tepat dosis 82,4%, tepat cara pemberian 100%, tepat lama pemberian 91,1%, dan tepat interval waktu pemberian 76,5%.
UNIFORMITY OF WEIGHT TESTING OF THE RECIPE MIXTURE FOR THE QUALITY OF PARACETAMOL POWDER FOR PEDIATRIC PATIENTS AT KHODIJAH PHARMACY IN JOMBANG REGENCY IN 2022: Uji Keseragaman Bobot Resep Racikan Terhadap Kualitas Serbuk Bagi (Pulveres) Paracetamol Pada Pasien Anak di Apotek Khodijah Kabupaten Jombang Tahun 2022 Yuneka Saristiana; Fendy Prasetyawan; Charliandri Saputra Wahab; Nanda Ardianto; Lily Aina
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 4 No. 2 (2023): Jurnal Inovasi Farmasi Indonesia (JAFI)
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Jenis sediaan farmasi yang sering digunakan untuk anak dan bayi adalah serbuk. Ada dua jenis serbuk oral yaitu terbagi (pulveres) dan tidak terbagi (pulvis). Sediaan pulveres digunakan paling banyak pada pasien anak, mencapai 38% dibandingkan dengan sediaan lain seperti sirup, kapsul, injeksi, dan inhalasi. Ketidakseragaman bobot pada sediaan pulveres dapat terjadi akibat pembagian yang tidak merata, dan ini dapat menyebabkan perubahan dosis. Penelitian digunakan untuk menilai keseragaman bobot resep pulveres mengukur serbuk paracetamol berdasarkan standar farmakope dan persyaratan kualitas yang berlaku. Penelitian ini merupakan ekperimental dengan pendekatan deskriptif dan mengunakan desain Cross sectional dengan menggunakan alat sebagai timbangan analitik milligram. Persyaratan dalam Farmakope Indonesia Edisi III, keseragaman bobot parasetamol dalam resep racikan sediaan serbuk bagi (pulveres) bentuk bungkus (puyer) di apotek Khadijah kabupaten Jombang tidak mencapai standar yang ditetapkan, dengan hanya mencapai 27%.
Evaluasi Keamanan dan Efektifitas Antiviral Pada Pasien COVID-19 Dengan Penyakit Ginjal Kronis Fendy Prasetyawan; Charliandari Saputra Wahab; Putri Ayu Iramadona; Dyah Anisa Indri Erawati
Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Vol 9, No 2 (2023): JMK Yayasan RS.Dr.Soetomo, Oktober 2023
Publisher : STIKES Yayasan RS.Dr.Soetomo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29241/jmk.v9i2.1687

Abstract

Pasien yang mengalami gagal ginjal kronik cenderung memiliki risiko yang lebih tinggi terhadap infeksi COVID-19 yang parah. Diperlukan penelitian efektifitas terhadap obat antiviral pada pasien COVID-19 disertai gagal ginjal kronik. Tujuan penelitian untuk mengetahui tingkat keparahan penyakit dan tingkat keefektivan obat antiviral  pada pasien COVID-19 dengan PGK setelah diberikan pengobatan antiviral di RSUD dr. Soedomo Trenggalek. Penelitian ini merupakan penelitian cross sectional (non experimental). Pengambilan sampel menggunakan metode purposive sampling. Data yang digunakan berupa data restrospektif menggunakan data rekam medis tahun 2022 dengan diagnosis pasien COVID-19 dengan PGK. Hasil dari penelitian adalah obat antiviral efektif untuk diberikan pada pasien COVID-19 dengan penyakit ginjal kronik untuk mengurangi kadar inflamasi dengan nilai p-value 0,000 tetapi kurang efektif jika untuk memperbaiki saturasi oksigen pada pasien dibuktikan dengan SpO2 memiliki nilai p-value 0,063. Keamanan penggunan obat antiviral juga tidak disarankan untuk pasien dengan penyakit ginjal kronik hal ini didukung oleh nilai p-value  ClCr sebesar 0,842.
Virtual Socialization about the Use of Family Medicinal Plants (TOGA) as an Alternative for Treatment Ratna Mildawati; Bandhi Prasetya Nugroho; Fendy Prasetyawan; Ary Kristijono; Yuneka Saristiana; Isma Oktadiana; Arlan K Imran
Assoeltan: Indonesian Journal of Community Research and Engagement Vol. 1 No. 2 (2023): Indonesian Journal of Community Research and Engagement
Publisher : Edujavare Publishing

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Abstract

The use of plants as a treatment solution, whether as preventive, promotive or curative therapy, is becoming popular again with the public due to the trend of back to nature medicine. Family Medicinal Plants (TOGA) are plants that have medicinal properties and grow around community yards which are managed by families and planted to meet the family's medicinal needs. The development and utilization of family medicinal plant cultivation is very necessary to support public health. This activity is carried out in an effort to provide knowledge to improve health. The target of this health education activity is housewives. The activity method carried out in this community service is outreach using the lecture method and using power point slides which contain explanations of several types of superior family medicinal plants and by inviting the public to plant TOGA. The success of this community service is assessed from the target number of participants of 75%, achievement of goals of 80%, achievement of material targets of 80% and success of planting TOGA at home 80%. The conclusion of this community service is that TOGA education increases people's knowledge and understanding of TOGA
Prediction of Pinostrobin Pharmacokinetics from Temu Kunci (Boesenbergia rotunda (L.) Mansf.) Using pkCSM Faisal Akhmal Muslikh; Anis Akhwan Dhafin; Fendy Prasetyawan
Contemporary Journal of Applied Sciences Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/cjas.v1i1.6977

Abstract

Indonesia is a megabiodiversity country with the second-largest abundance of biodiversity in the world. Temu kunci (Boesenbergia rotunda (L.)) is a well-known traditional medicinal plant in Indonesia with many nutritional and therapeutic benefits. It is known to have good pharmacological activity, which is due to the content of secondary metabolites commonly known as pinostrobin. However, more scientific data is still needed to justify its increased use, especially regarding its pharmacokinetics and safety. The aim of the research was to predict the pharmacokinetic properties of pinostrobin compounds. The pinostrobin compound was obtained from PubChem, accessible at https://pubchem.ncbi.nlm.nih.gov/, and then pharmacokinetic analysis was carried out using a web tool (https://biosig.lab.uq.edu.au/pkcsm/prediction). The research results show that the pinostrobin compound is a compound that has pharmacokinetic properties, showing that this compound has poor distribution and toxicity capabilities.
The Efficacy of Antiviral Medications in Managing Blood Oxygen Levels in Covid-19 Patients Afflicted by Chronic Kidney Conditions Fendy Prasetyawan; Faisal Akhmal Muslikh; Anis Akhwan Dhafin; Elsa Mahardika Putri; Yuneka Saristiana; Susilo Margining Raharjo
Contemporary Journal of Applied Sciences Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/cjas.v1i1.7030

Abstract

This research assesses the efficacy and safety of employing antiviral drugs in individuals with COVID-19 and chronic kidney disease. The study results reveal a reduced effectiveness of the drug in enhancing oxygen saturation in patients, as indicated by a p-value of 0.026 for SpO2. Consequently, the administration of antiviral drugs to individuals with chronic kidney disease warrants careful consideration. Moreover, there is a need to pay attention to the safety aspects of antiviral drug utilization, particularly with a p-value of 0.026 for Clcr. It is advisable to refrain from using specific antiviral drugs, such as favipiravir, in COVID-19 patients with chronic kidney conditions. However, contemplating the use of remdesivir at an appropriate dosage may be viable if the patient's glomerular filtration rate (GFR) exceeds 30 ml/minute. The study's conclusion underscores the significance of meticulous and personalized management when employing antiviral drugs in COVID-19 patients with chronic kidney disease. A comprehensive consideration of factors such as effectiveness, safety, and the patient's renal health is imperative to ensure an optimal and tailored treatment approach.
Total Plate Count Test for Bacteria in Home industry Baby Porridge in the Malang City Area Anis Akhwan Dhafin; Elsa Mahardika Dhafin; Faisal Akhmal Muslikh; Fendy Prasetyawan
Contemporary Journal of Applied Sciences Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/cjas.v1i1.7036

Abstract

The growth and development of toddlers greatly influences the quality of human resources in the future so that the toddler years are an important period in human development. In nutritional development, food has an important role in growth. During the toddler years, apart from breast milk, babies also need additional food, namely MP-ASI. MP-ASI can be contaminated by chemical and biological contaminants, one of the biological contaminants in food is bacteria. The TPC (Total Plate Count) test is a test used to count the number of bacterial colonies in the media being tested. The stages carried out before testing are sample dilution and media formulation. This research aims to determine whether or not there are bacteria in samples of Home industry Baby Porridge sold in the city of Malang. The samples studied were 8 samples. The sampling technique was carried out by purposive sampling. Based on the research that has been carried out, it can be concluded that of the 8 samples of home industry baby porridge sold in the city of Malang, 2 samples meet the requirements with the condition that the number of colonies is 2 x 10 2 colonies/g. The remaining 6 samples did not meet the requirements.
Efficacy of Antiviral Medications in Decreasing Inflammation Levels Among Covid-19 Patients Experiencing Chronic Kidney Disease (CKD) Fendy Prasetyawan; Faisal Akhmal Muslikh; Anis Akhwan Dhafin; Elsa Mahardika Putri; Yuneka Saristiana; Susilo Margining Raharjo
Contemporary Journal of Applied Sciences Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/cjas.v1i1.7037

Abstract

Individuals with Chronic Kidney Disease (CKD) face an elevated risk of severe COVID-19 infection. A comprehensive investigation into the effectiveness of antiviral medications in treating COVID-19 patients is imperative. The primary goal is to assess the severity of the illness and the efficacy of antiviral drugs in individuals with COVID-19 and CKD following antiviral treatment at Dr. Soedomo Trenggalek Hospital. This study adopts a cross-sectional approach, employing purposive sampling for sample selection. Retrospective data from 2022 medical records of COVID-19 patients diagnosed with CKD are analyzed. The research findings highlight the efficacy of antiviral drugs in diminishing inflammation levels in COVID-19 patients, as indicated by a significant p-value of 0.000. However, the leukocyte data proved inadequate in determining the reduction in inflammatory levels. Therefore, obtaining data on C-reactive protein (CVR) and lymphocytes is crucial for a more accurate measurement. The p-value for ClCr is 0.842.