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All Journal JURNAL FARMASIMED (JFM) Jurnal Pengmas Kestra (JPK)
Aminah Syarifuddin
1995
Health Professions Medicine & Pharmacology Nursing Public Health

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PELATIHAN PEMANFAATAN EKSTRAK KULIT TERONG UNGU (SOLANUM MELONGENA L) SEBAGAI PEWARNA ALAMI DALAM PRODUK KOSMETIK KRIM PERONA MATA Aminah Syarifuddin; Aulia Syahfitri; Nur Ulina Turnip; Novandi Purba
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (470.207 KB) | DOI: 10.35451/jpk.v1i2.898

Abstract

Tanaman terong ungu (Solanum melongena L) tumbuhan yang dikenal bahkan dikonsumsi orang sebagai sayur. Tumbuhan terong ungu juga dapat dimanfaatkan sebagai obat tradisional seperti menurunkan kadar kolesterol. Terung ungu (Solanum Melongena L) merupakan salah satu tanaman yang mengandung antosianin yang tinggi segingga dapat digunakan sebagai Pewarna alami pada sediaan kosmetika. Tujuan pada penelitian ini memformulasikan sediaan krim perona mata mengandung ekstrak kulit terong ungu sebagai pewarna dan melihat perbedaan warna dari variasi konsentrasi masing masing sediaan. Konsentrasi ekstrak kulit terong ungubyang digunakan adalah F0: 0%, F1: 8%, F2: 12%, F3: 16%. Metode ekstraksi yang digunakan yaitu metode maserasi. Evaluasi sediaan yang dilakukan yaitu pemeriksaan organoleptis, homogenitas, uji oles, uji stabilitas, pH, tipe krim dan iritasi. Hasil evaluasi menunjukkan bahwa tipe krim air dalam minyak (A/M), uji oles baik, stabil, sifat fisik semua formula krim perona mata berbentuk setengah padat, warna coklat muda, bau minyak mawar, homogeny, pH rata rata dari 4,9-6,07, tidak mengakibatkan iritasi. Kesimpulan: Ekstrak etanol kulit terong ungu (Solanum melongena L) dapat digunakan sebagai pewarna alami dalam sediaan krim perona mata. Kata Kunci: Krim Perona Mata, Ekstrak Etanol, Kulit Terong Ungu.
Socialization of The Use of Melinjo Leaf Ethanol Extract (Gnetum gnemon L.) on Growth Salmonella typhi Bacteria Aminah Syarifuddin; Chandra Pranata; Novidawati Boru Situmorang; Debi Dinha Octora; Lili Ramadhani
JURNAL PENGMAS KESTRA (JPK) Vol. 3 No. 1 (2023): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v3i1.1149

Abstract

Gnetum gnemon L. has antibacterial activity against Salmonella typhi because it contains flavonoids, saponins, tannins, alkaloids, and steroids. Where these compounds play an important role as an antibacterial. The purpose of this service is to provide information to the public regarding the benefits of melinjo leaves which can act as an antibacterial agent. This service activity is carried out in the form of socialization using lecture, question and answer, and demonstration methods. The number of participants in this community service activity was 20 pharmacists at Grandmed Lubuk Pakam Hospital. Based on the results of the PkM activities carried out, it can be stated that there has been an increase in public knowledge regarding the efficacy of melinjo leaves as an antibacterial substance. This can be proven by the increase in post-test scores when compared to pre-test scores. The average increase in the knowledge of PkM participants was 21.5. On the other hand, the highest post-test score obtained was 85, while the lowest post-test score was 60. Meanwhile, based on the PkM material that had been socialized, the PkM participants understood that the results of phytochemical tests on melinjo leaf Simplicia showed that melinjo leaf extract contains compounds alkaloids, flavonoids, steroids, saponins, and tannins. Meanwhile, the antibacterial test showed that the inhibition zones of various concentrations included a moderate concentration of 40%, a moderate category of 60%, and a strong category of 80%. The average diameter of the inhibition zone increased with each concentration of melinjo leaves.
THE EFFECT OF ETHANOL EXTRACT OF SOURSOP LEAVES (ANNONA MURICATA L.) ON BODY TEMPERATURE IN MALE MICE (MUS MUSCULUS) INFECTED WITH BACTERIA SALMONELLA TYPHI Aminah Syarifuddin; Cucu Arum Dwi Cahya; Amelya Chyntia Br Sihombing
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1929

Abstract

Soursop leaves (Annona muricata L.) are a plant that has many health benefits that can be obtained from the fruit, leaves, and seeds. Soursop leaves contain saponins, flavonoids, tannins, and alkaloids which can act as an antiseptic-disinfectant or as an antibacterial. Flavonoid compounds can be used as wound medicine, antifungal, antimicrobial, anticancer, and antiviral. In society, it is used by boiling the leaves and then drinking the boiled water. This research aims to determine the effectiveness of soursop leaf ethanol extract as an antibacterial against Salmonella typhi so that fever can be reduced. The dosage includes 100; 150; 200; and 250 mg/kg BW. No treatment was given as a negative control and chloramphenicol tablets as a positive control. Based on data analysis, it shows that there is a significant difference in body temperature after being tested using the t-test with a value of 0.000 < 0.05. These results prove that body temperature which was initially normal during the acclimatization stage experienced an increase in body temperature when infected with Salmonella typhi. The results of the One-Way ANOVA test also showed an effect on reducing body temperature infected with Salmonella typhi. From several doses, the EDDS dose of 100 mg/kg BW was able to reduce body temperature by an average of 36.5°C.
Co-Authors Amelya Chyntia Br Sihombing Aulia Syahfitri Chandra Pranata Cucu Arum Dwi Cahya Debi Dinha Octora Sitepu Lili Ramadhani Novandi Purba Novidawati Boru Situmorang Nur Ulina Turnip