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Damayanti Iskandar
Universitas Islam Negeri Raden Fatah Palembang
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Uji Efektivitas Ekstrak Biji Lamtoro (Leucaena leucocephala) sebagai Insektisida terhadap Kecoa Amerika (Periplaneta americana) Adelia, Yuanda Wanda; Iskandar, Damayanti
Jurnal Riset Kimia Vol 11, No 2 (2020): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v11i2.354

Abstract

Research on the effectiveness of lamtoro seeds (Leucaena leucocephala) extract has been carried out as an insecticide against American cockroaches (Periplaneta americana). The lamtoro seeds were extracted using maceration method with ethanol solvent, and obtained ethanol extract of lamtoro seeds. Lamtoro seeds extract was made in 5 concentrations of 0%, 2%, 6%, 10% and 14%. The effectiveness of the extract was tested using spray method with 10 adult cockroaches as a testing animal with 3 times repetition and observed for 72 hours. Observations have shown the decline in American cockroaches’ activity is causing death. Mortality data were analyzed using probit analysis to determine LC50. The result of phytochemical test of lamtoro seeds extract are flavonoids, tannins and saponins. Lamtoro seeds extract was effective to kill American cockroaches, which percentage of mortality were 0%, 33%, 66%, 86% and 96% respectively at concentration 0%, 2%, 6%, 10%, and 14% with LC50 3,35%. 
Uji Efektivitas Ekstrak Biji Lamtoro (Leucaena leucocephala) sebagai Insektisida terhadap Kecoa Amerika (Periplaneta americana) Yuanda Wanda Adelia; Damayanti Iskandar
Jurnal Riset Kimia Vol. 11 No. 2 (2020): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v11i2.354

Abstract

Research on the effectiveness of lamtoro seeds (Leucaena leucocephala) extract has been carried out as an insecticide against American cockroaches (Periplaneta americana). The lamtoro seeds were extracted using maceration method with ethanol solvent, and obtained ethanol extract of lamtoro seeds. Lamtoro seeds extract was made in 5 concentrations of 0%, 2%, 6%, 10% and 14%. The effectiveness of the extract was tested using spray method with 10 adult cockroaches as a testing animal with 3 times repetition and observed for 72 hours. Observations have shown the decline in American cockroaches’ activity is causing death. Mortality data were analyzed using probit analysis to determine LC50. The result of phytochemical test of lamtoro seeds extract are flavonoids, tannins and saponins. Lamtoro seeds extract was effective to kill American cockroaches, which percentage of mortality were 0%, 33%, 66%, 86% and 96% respectively at concentration 0%, 2%, 6%, 10%, and 14% with LC50 3,35%. 
PEMANFAATAN EKSTRAK DAUN KITOLOD (Hippobroma Longiflora (L) G.Don) SEBAGAI BAHAN AKTIF SEDIAAN TABIR SURYA Dila Savira; Damayanti Iskandar
Jurnal Kimia Riset Vol. 5 No. 1 (2020): Juni
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v5i1.19680

Abstract

Telah dilakukan penelitian untuk memanfaatkan ekstrak daun kitolod  (Hippobroma longiflora (L) G. Don) sebagai tabir surya. Daun kitolod di ekstraksi secara maserasi dengan pelarut metanol kemudian di fraksinasi menggunakan n-heksana dan etil astetat. Kandungan kimia yang diperoleh dari ekstrak etil asetat adalah flavonoid, alkaloid, dan steroid. Untuk mengetahui aktivitas ekstrak tersebut dilakukan pengujian dengan cara mengukur absorbansi larutannya pada tingkat konsentrasi tertentu dengan menggunakan spektrofotometri UV-Vis. Nilai SPF yang diperoleh dari konsentrasi 100 ppm, 200 ppm, 300 ppm, 400 ppm, dan 500 ppm berturut-turut sebesar 4,3; 10,3; 15,2; 21,5; dan 28. Konsentrasi 100 ppm termasuk kedalam SPF kategori proteksi sedang, konsentrasi 200 ppm termasuk kedalam SPF kategori proteksi maksimal. Konsentrasi 300 ppm, 400 ppm, 500 ppm termasuk kedalam SPF  kategori proteksi ultra.Kata Kunci : Daun Kitolod, Tabir Surya, SPF.
UJI AKTIVITAS TANIN DAUN MIMBA (Azzadirachta indica) TERHADAP BAKTERI Salmonella typhi Derys Ruwandha; Dwi Fitriyani; Damayanti Iskandar
Jurnal Kimia Riset Vol. 6 No. 1 (2021): Juni
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v6i1.24848

Abstract

Pengobatan terhadap penyakit tipus masih menjadi masalah utama karena penggunaan obat-obatan sintetik terkadang memberikan efek samping terhadap tubuh, sehingga diperlukan alternatif pengobatan dari bahan alam. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri senyawa tanin daun mimba (Azzadirachta indica) terhadap bakteri Salmonella Typhi dengan menggunakan metode difusi cakram. Uji aktivitas antibakteri ditentukan berdasarkan diameter daya hambat senyawa tanin terhadap bakteri Salmonella typhi. Uji Fitokimia Ekstrak metanol daun mimba positif mengandung tanin, flavonoid, alkaloid, steroid, dan saponin. Pemisahan senyawa tanin dari ekstrak metanol menghasilkan nilai rendemen sebesar 69.6 %. Hasil pengujian antibakteri senyawa tanin dapat menghambat bakteri Salmonella typhi berturut-turut pada konsentrasi 15%, 30%, 50%, dan 75% yaitu sebesar 15.03, 16.78, 19.02, 21.78 mm dengan klasifikasi kuat sampai sangat kuat berdasarkan klasifikasi Davis & Stout.
Synthesis of Compounds Acetyl Vanilat as Analgesic Compound Components Damayanti Iskandar; Susy Yunita Prabawati
Jurnal ILMU DASAR Vol 17 No 2 (2016)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.098 KB) | DOI: 10.19184/jid.v17i2.2683

Abstract

Acetyl vanillate was synthesized to become an analgesic compound was conducted in two stages.The first stage is oxidation vanillin using Tollens reagent. The result of the oxidation wascharacterized by melting point and FTIR. The second stage, vanillic acid was acetylated usingacetic acid anhydrous under two conditions, that are acid and base using H2SO4 and NaOH 10%,respectively. Two difference products from those processes were characterized using FTIR and1H-NMR. The result of the melting point vanillic acid test showed 204°C and the standard is210°C. Vanilline was successfully oxidized, based on comparison FTIR spectra between vanillineand its precursor that showed no functional group of C-H aldehyde at 2,700-2,800 cm-1. Thecharacteristics FTIR spectra under base conditions showed no absorption of functional group ‒OHthat substituted by an acetyl group. So that, the base catalyst indicated no product of the expectedcompound. The product under acidic compounds have the characteristic yellow crystals with amelting point of 130°C. Characteristics of FTIR showed no width absorption at wave number 3400cm-1 and evidenced by 1H-NMR spectra. Shift peak at 2.342 ppm was an absorption acetylcompounds. It was concluded that acetylation of acetyl vanillate compounds under acidicconditions to produce the expected product.Keywords: vanilin, vanilic acid, acetylation
Cytotoxicity Assay of 2,4-Dihydroxide-4’-Methoxychalcone Against Cervical (HeLa) Cancer Cell by MTT Assay Novia Suryani; Sabirin Matsjeh; Mutmainah Mutmainah; Daratu Eviana Kusuma Putri Eviana Kusuma Putri; Damayanti Iskandar; Syarifah Asyura
Biota Vol 13 No 1 (2020)
Publisher : Universitas Islam Negeri Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/jb.v13i1.235

Abstract

Chalcone is one of the phenolic group secondary metabolic with numerous biological activity. Many studies have shown that chalcone derivatives compound has anticancer, anti-inflammatory, antimalarial, and antibacterial activities. The purpose of this research was to study the prediction potency unsaturated carbonyl system of chalcone derivative against the HeLa cell by MTT assay. Those activities assumed can inhibit the mechanism action of NF-kB that caused cervical cancer. The 2,4-dihydroxide-4’-methoxychalcone has done synthesis as a target compound by a sonochemical for 7 hours. The results showed that chalcone derivative most active against the HeLa cell.
Efektivitas Ekstrak Daun Matoa (Pometia pinnata) sebagai Antibakteri Staphylococcus epidermidis Rossalinda Rossalinda; Fitria Wijayanti; Damayanti Iskandar
Stannum : Jurnal Sains dan Terapan Kimia Vol 3 No 1 (2021): April 2021
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v3i1.2133

Abstract

A natural alternative that can be used to inhibit the growth of Staphylococcus epidermidis bacteria is matoa leaves (Pometia pinnata). Matoa leaves contain secondary metabolites such as flavonoids, tanins, and saponins which are known as an antibacterial. The purpose of this study was to determine the effectiveness of matoa leaves extract as an antibacterial agent for Staphylococcus epidermidis. This study used the disc diffusion method, using deodorant as a positive control, aquadest as a negative control and concentration variations matoa leaves extract of 15%, 20%, 25% and 30%. The matoa leaves were extracted using the maceration method with 96% ethanol. Antibacterial testing in this study was characterized by a clear zone or zone of inhibition around the disc paper. The results of the antibacterial test in this study have to different inhibition zones, that is a sample concentration of 15% the inhibition zone value is 0,125 mm. The sample concentration of 20% the inhibition zone is 3 mm. The sample concentration of 25% the inhibition zone is 2,312 mm and the sample concentrasion of 30% the inhibition zone is 0,875 mm. The extract of matoa leaves can be used as an antibacterial, because according to Pan Chen Wu Tang and zao (2009) the extract of matoa leaves could be applied as inhibitor of the growth of Staphylococcus epidermidis at a sample concentration of 20% is in the weak to moderate category
PENENTUAN NILAI SPF (Sun Protection Factor) EKSTRAK ETANOL DAUN SEMBUKAN (Paederia foetida L.) SEBAGAI TABIR SURYA Damayanti Iskandar
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol 3, No 1 (2021): Vol.3 No.1 Desember 2021
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v3i1.2323

Abstract

Penelitian ini bertujuan untuk mengetahui bagaimana efektivitas senyawa metabolit sekunder yang terkandung dalam ekstrak etanol daun sembukan (Paederia foetida L.) sebagai tabir surya. Pengujian dilakukan dengan menentukan senyawa metabolit sekunder yang berada dalam ekstrak etanol daun sembukan (Paederia foetida L.) secara kualitattif, kemudian dilanjutkan dengan pengujian menggunakan spektrofotometri UV-Vis, untuk memperoleh nilai SPF (Sun Protection Factor). Hasil penelitian menunjukkan bahwa adanya kandungan senyawa alkaloid, flavonoid dan tanin. Nilai SPF (Sun Protection Factor) yang diperoleh secara bertururt-turut pada konsetrasi 200 ppm, 400 ppm, 600 ppm, 800 ppm, dan 1000 ppm, memiliki nilai SPF yang meningkat mulai dari 4,47, 6,79, 13,27, 17,49, dan 20,91. Pada proteksi SPF ekstra terdapat pada konsentrasi 400 ppm, dan untuk nilai proteksi SPF ultra terdapat pada konsentrasi 800 ppm dan 1000 ppm. Berdasarkan uraian tersebut maka dapat dikatakan daun sembukan (Paederia foetida L.) memiliki potensi sebagai bahan dasar sediaan tabir surya.
Potential Ethanol Exract Kapuk Randu Leaves (Ceiba petandra (L.) Gaertn) as Sunscreen Resi Andela; Damayanti Iskandar; DF Yani
ALCHEMY:Journal of Chemistry Vol 10, No 2 (2022): ALCHEMY: Journal of Chemistry
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v10i2.13085

Abstract

Matahari merupakan sumber cahaya alami yang berperan sangat penting bagi kehidupan untuk fotosintesis tumbuhan serta sebagai sumber vitamin D bagi tubuh. Namun juga berdampak buruk bagi kesehatan kulit jika terpapar dalam jumlah berlebihan. Salah satu alternatif yang dapat digunakan untuk mencegah dampak radiasi sinar matahari yang berlebihan adalah tabir surya. Sehingga dilakukan penelitian untuk mengetahui aktivitas dan nilai SPF (Sun Protection Factor) ekstrak etanol daun kapuk randu (Ceiba petandra (L.) Gaertn) pada konsentrasi 100, 200, 300, 400 dan 500 ppm. Penelitian ini dilakukan secara in vitro menggunakan spektrofotometer UV-Vis pada panjang gelombang 290-320 nm. Hasil pengujian menunjukkan bahwa ekstrak etanol daun kapuk randu memiliki aktivitas proteksi dengan nilai SPF berturut-turut pada konsentrasi 100, 200, 300, 400 dan 500 ppm yaitu 3 (perlindungan minimal); 6. 9 (perlindungan ekstra); 10.4 (perlindungan maksimal); 13.9 (perlindungan maksimum) dan 17,4 (perlindungan ultra). Berdasarkan nilai SPF, ekstrak etanol daun kapuk randu mampu digunakan sebagai bahan aktif tabir surya dengan kandungan senyawa aktif tanin dan flavonoid.Kata kunci: Ceiba Petandra L.Gaertn, Tabir surya, SPF
PENGARUH PENAMBAHAN FLY ASH TERHADAP KUALITAS SEMEN DI PT SEMEN BATURAJA TBK Ana Maghpiroh; Damayanti Iskandar; Novadri anaser; Safaruddin Tohir
Jurnal Multidisipliner Bharasumba Vol 2 No 04 Oktober (2023): Jurnal Multidisipliner Bharasumba
Publisher : Pusat Studi Ekonomi, Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Fly Ash or fly ash is solid waste produced from burning coal in power plants. Fly Ash was previously obtained from the simple production of burning coal with a gas funnel and dispersed into the atmosphere. The use of Fly Ash on OPC type cement was carried out in this test with varying percentages of 2%, 4%, 6%, 8%, 10%, 12%, 14%. The test was carried out by adding an additive (Fly Ash) to the basic material for making OPC cement. Next, testing the chemical composition properties of Fly Ash using Xray, testing the physical properties of cement, namely testing the compressive strength resulting from molding the mortar and testing the setting time. Meanwhile, testing the chemical properties of cement was carried out using IR (insoluble residue) and SO3. From the results of this research, it was found that the addition of Fly Ash had a positive impact on 7 day compressive strength, setting time and SO3. The addition of Fly Ash from low to high percentages can increase the fineness of the cement so that it affects the setting time and compressive strength of the cement. From this research it was found that the addition of additives (Fly Ash) can improve the quality of OPC cement and in general it is not much different from the physical properties of PCC cement.
Co-Authors Adelia, Yuanda Wanda Ana Maghpiroh Daratu Kusuma Eviana Putri Derys Ruwandha DF Yani Dila Savira Dwi Fitri Yani Fitri Oviyanti Mutmainah Mutmainah Novadri anaser Novia Suryani Resi Andela Rossalinda Rossalinda Sabirin Matsjeh Safaruddin Tohir Susy Yunita Prabawati Syarifah Asyura Yuanda Wanda Adelia