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All Journal Jurnal Studi Pemerintahan JAKPP : Jurnal Analisis Kebijakan & Pelayanan Publik ad-Dawaa : Journal of Pharmaceutical Sciences PINISI Discretion Review The International Journal of Politics and Sociology Research
Gita Susanti, Gita
Department of Public Administration, Universitas Hasanudin, Makassar, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences

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Kerjasama Publik Dan Swasta Dalam Pengelolaan Parkir Di Kota Makassar Rukmana, Novayanti Sopia; Susanti, Gita
JAKPP : Jurnal Analisis Kebijakan & Pelayanan Publik Volume 1 Number 2, Desember 2015
Publisher : Departemen Ilmu Administrasi FISIP UNHAS

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Abstract

Kerjasama Pemerintah-Swasta (Public Private Partnership) dipandang penting untuk memenuhi ketersediaan sarana prasarana dan peningkatan pelayanan kebutuhan dasar masyarakat termasuk dalam pengelolaan parkir. Penelitian ini bertujuan untuk mengetahui bagaimana penentuan kontrak dalam kemitraan pengelolaan parkir dan pelaksanaan kemitraan pengelolaan parkir antara RSUP dR Wahidin Sudirohusodo dengan PT ISS. Penelitian ini menggunakan pendekatan kualitatif. Pengumpulan data ditempuh melalui pengamatan, wawancara dan dokumentasi terhadap informan yang terlibat langsung dalam pelaksanaan kegiatan tersebut. Proses analisis data meliputi reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa : (1) Penentuan kontrak dalam kemitraan pengelolaan parkir antara RSUP DR Wahidin Sudirohusodo dengan PT ISS membawa dampak baik dan saling menguntungkan. (2) Pelaksanaan kemitraan dalam pengelolaan parkir antara RSUP dR Wahidin Sudirohusodo dengan PT ISS belum sepenuhnya berjalan secara maksimal.
Model Jaringan Kebijakan Publik (Perumusan Kebijakan Masyarakat Adat Ammatoa Kajang Di Kabupaten Bulukumba) Hidayat, Andi Rahmat; Alwi, Alwi; Susanti, Gita
JAKPP : Jurnal Analisis Kebijakan & Pelayanan Publik Volume 1 Number 2, Desember 2015
Publisher : Departemen Ilmu Administrasi FISIP UNHAS

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Abstract

Perumusan kebijakan dengan pendekatan jaringan penting dalam menyelesaikan problem sosial yang bersifat kompleks dan merancang kebijakan berbasis pemberdayaan sehingga melalui tim perumus kebijakan masyarakat adat ammatoa kajang sebagai wadah jaringan, pihak yang berkepentingan dapat mengakses proses perumusan kebijakan tersebut untuk mempengaruhi keputusan yang dibuat oleh pemerintah daerah Kabupaten Bulukumba. Penelitian ini bertujuan mengetahui dan menganalisis proses jaringan perumusan kebijakan masyarakat adat ammatoa kajang di Kabupaten Bulukumba. Metode penelitian yang digunakan adalah metode kualitatif. Pengumpulan data ditempuh melalui  pengamatan, wawancara dan dokumentasi terhadap informan yang terlibat langsung dalam pelaksanaan kegiatan tersebut. Proses analisis data meliputi reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukan bahwa : (1) aktor pada tim perumus kebijakan terutama pemerintah daerah dan LSM memiliki posisi yang seimbang. (2) fungsi jaringan kebijakan belum berjalan dengan semestinya. (3) struktur jaringan bersifat konsultatif, namun overlapping membership tidak membawa dampak positif pada efektifitas jaringan. (4) pelembagaan pada jaringan kebijakan berjalan dengan baik. (5) pola interaksi atau kebiasaan yang mengatur pertukaran sumber daya bersifat konsultatif. (6) distribusi kekuasaan terjadi cukup signifikan ditandai adanya kegiatan riset partisipatif yang dilakukan oleh LSM. (7) strategi riset menjadi kunci LSM mampu merubah perspektif pemerintah daerah dalam menetapkan luas wilayah dan hutan adat. Terdapat kelemahan  pada jaringan perumusan kebijakan masyarakat adat ammatoa kajang dimana pemerintah daerah mendominasi jumlah aktor pada tim perumus. Meskipun demikian, LSM nampak berhasil menjembatani kepentingan masyarakat adat namun penempatan Labbiriyah (Camat Kajang) sebagai satu-satunya pemangku adat pada tim perumus kurang tepat karena Labbiriyah cenderung merepresentasikan kepentingan pemerintah daerah dari pada kepentingan masyarakat adat pada proses perumusan kebijakan
Resources Exchange Model in Implementation Network of Fishermen Community Policy in Makassar City SUSANTI, GITA; ALWI, ALWI; TAMBA, LA
Jurnal Studi Pemerintahan Vol 8, No 1 (2017): February 2017
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (656.207 KB) | DOI: 10.18196/jgp.8153

Abstract

Public policy implementation network is a study that tried to accumulate all the stakeholders as potential resources to determine and implement a public policy. Fishermen community empowerment policy is the policy, which is complex be- cause it includes varied stakeholders. The main objective of this study is to develop a model of resources exchange in the implementation network of fisher- men community empowerment policy in Makassar City, which includes the avail- ability of resources and the rule of the game of resources exchange. This study uses qualitative design and case study strategy. Based on the pairing patterns technique, the availability of the resources needed by the fishermen group has not been sufficient to run his business. This is caused by a major source of fund- ing in this policy from the central government. Then, the fishermen community empowerment policy is still dominated by rule of the game of public bureau- cracy as the policy implementer in the resources exchange. Therefore, local gov- ernments need to develop the synergy with all stakeholders and establish a rule of the game based on the network-based organization.
Aaptamine Enhanced Doxorubicin Activity on B-Cell Lymphoma 2 (Bcl-2): A Multi-Structural Molecular Docking Study Setiawansyah, Arif; Susanti, Gita; Alrayan, Reza; Hadi, Ismanurrahman; Ikhlas Arsul, Muhammad; Luthfiana, Dewi; Wismayani, Leni; Hidayati, Nurul
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 7 No. 1 (2024)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v7i1.46796

Abstract

Doxorubicin, a widely used chemotherapeutic agent, targets Bcl-2, but its efficacy can be limited by drug resistance. Its combination with natural derived compound can be a therapeutic approach to overcome this problem. This study aimed to investigate the molecular interactions and binding affinities of aaptamine and doxorubicin with Bcl-2 using molecular docking simulations, and to evaluate the potential synergistic effects of their combination. Molecular docking studies were performed to predict the binding modes and affinities of aaptamine and doxorubicin along with their combination to Bcl-2. Molecular docking simulation results showed that aaptamine binds to the BH3 binding groove of Bcl-2, forming key interactions with residues like Asp70, Tyr67, Phe112 and Glu111. Aaptamine stabilized the binding of doxorubicin to Bcl-2 through hydrophobic bonding and van der Waals interactions, resulting in enhanced binding affinity. The combination of aaptamine and doxorubicin exhibits synergistic anticancer effects by enhancing the binding affinity of doxorubicin to Bcl-2. Molecular docking simulations provided insights into the stabilizing interactions between aaptamine, doxorubicin, and Bcl-2, suggesting a potential strategy for overcoming Bcl-2-mediated drug resistance in cancer. However, further in vitro investigation is needed to be implemented.
Integrating The Network Pharmacology and Molecular Docking to Uncover The Potential Mechanism Of Rutin In Fighting Diabetes Mellitus Putri, Stella Anatasya Putri; Maharani, Andi Rani Gustia; Luthfiana, Dewi; Nweze, Leonard Chinecherem; Setiawansyah, Arif; Susanti, Gita; Doloking, Haeria
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 7 No. 1 (2024)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v7i1.49701

Abstract

Introduction: Rutin is a flavonol glycoside that is known to have blood sugar reducing activity. However, its molecular mechanism in reducing blood sugar level remains unclear. This study was employed to elucidate the pharmacological mechanism of rutin as antidiabetic agent. Methods: Potential target of rutin was screened in relevant databases to construct a compound-target network. Network pharmacology was utilized to identify targets associated with disease, gene ontology and KEGG pathways and confirmed its potential binding affinity using Autodock 4.2 assisted by ADT interface. Result: The result highlighted mTor, PIK3R1, and NFKB1R as a potential target of Rutin through network pharmacology. This target involved in the insulin signaling pathways, insulin resistance, type 2 diabetes mellitus, B receptor signaling pathways, AGE-RAGE signaling pathway in diabetic complications and pancreatic cancer. All docking protocols were valid with RMSD value for TNF-a, NF-KB, PI3K were 0.72 Å, 0.67 Å, ​​and 0.54 Å, respectively. The molecular docking has confirmed the potential mechanism of rutin as antidiabetic agent by stably bound with these proteins with estimated free binding energy values of -8.54 kcal/mol (NF-KB), -8.01 kcal/mol (PI3K), and -6.22 kcal/mol (TNF-a). Conclusion: The study has given insight into the molecular mechanism of rutin in the management of DM by stably bound with NF-KB, TNF-a, and PI3K. However, further laboratory experimental research is needed, particularly in vitro and in vivo assay
Implementation to accelerate stunting reduction in Sinjai District Firman, Firman; Alwi, Alwi; Susanti, Gita
The International Journal of Politics and Sociology Research Vol. 12 No. 2 (2024): September: Law, Politic and Sosiology
Publisher : Trigin Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/ijopsor.v12i2.253

Abstract

Stunting is one of the main problems in the health sector. Indonesia is ranked fourth in the world and second in Southeast Asia as the country with the most stunting cases. Data from the 2019 Indonesian Toddler Nutritional Status (SSGBI) survey shows that the stunting prevalence rate in Indonesia reached 27.7% (WHO threshold of 20%). This indicates that one in four children under five in Indonesia is stunted. Children who suffer from stunting may never reach their full genetic height Children who suffer from stunting and/or wasting also suffer from weakened immunity, increased risk of death and death, and are vulnerable to long-term developmental delays. Stunting is an indicator of chronic malnutrition which is associated with negative impacts on health and cognition during childhood and continuing into adulthood. In 2020, 149 million children experienced stunting. As in previous years, the rate of decline is so slow that the global target of reducing the number of stunted children under 5 years old to 100 million by 2025 will not be achieved. Only 25% of countries can meet the UN Sustainable Development Goal (SDG) target for stunting by 2020, with the largest proportion being in the WHO region of Asia compared to less than 10% in Africa. However, for many low- and middle-income countries (LMICs) with fragile economies and majority vulnerable populations, whatever progress has been made in addressing the immediate and underlying causes of stunting, such as access to adequate nutrition for women and their babies, will have a detrimental impact.
Optimization of Career Development Through the Transformation of Administrative Position into Functional Position in Makassar City Kardiat, Yosar; Ibrahim, Muh Akmal; Ahmad, Badu; Susanti, Gita
PINISI Discretion Review Volume 7, Issue 2, March 2024
Publisher : Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/pdr.v7i2.61217

Abstract

The transfer of positions from administrative positions to functional ones is one of the ways to optimize the career development. policy for transferring positions was carried out without going through good preparation since it was established or at the time of its implementation. This study aims to analyze the optimization of career development through the transformation of administrative position into functional position in Makassar City. This study used a qualitative research method with the type of descriptive research. The data was collected through observation, in-depth interviews, and documentation. Data analysis techniques were carried out by data collection, data condensation, data display, and conclusions drawing/ verifying. The results show that in transformation position from administrative into functional can optimized the career development.
Co-Authors Ahmad, Badu Alrayan, Reza Alwi Alwi Andi Rahmat Hidayat, Andi Rahmat Arif Setiawansyah Doloking, Haeria Firman Firman Hadi, Ismanurrahman Ibrahim, Muh Akmal Ikhlas Arsul, Muhammad Kardiat, Yosar LA TAMBA, LA Luthfiana, Dewi Maharani, Andi Rani Gustia Novayanti Sopia Rukmana, Novayanti Sopia Nurul Hidayati Nweze, Leonard Chinecherem Putri, Stella Anatasya Putri Wismayani, Leni