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ADMINISTRATION OF RED ROSELLAâS PETALS EXTRACT (Hibiscus sabdariffa) INCREASE LEVEL OF SUPEROXIDE DISMUTASE (SOD) WISTAR RATS WHICH INDUCED BY REPETEADLY HEATED COOKING OIL Herdiani, Novera; Wirjatmadi, Bambang; Adriani, Merryana
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Background: Â repeatedly heated cooking oil is cooking oil that is used many times, had saturated fatty acids containing free radicals. Red rosella petals extract contains antioxidants to minimize the effects of repeatedly heated cooking oil that can raise the levels of SOD. The aim of this study was to analyzed the effect of red rosellaâsÂ petals extract againstÂ oxidative stress of WistarÂ ratsÂ wereÂ induced by repeatedly heated cooking oil with examine levels of Â serumÂ SOD.This research was conducted True Experimental Laboratory with a completely randomized design (CRD) and use the post test. The sample consisted of 24 male rats were divided 4 groups: negative control (fed with standard diet); positive control (fed with standard diet + administered by repeatedly heated cooking oil as much as 2.1 ml / kg bw); treatment group dose I (fed with standard diet + administered by red rosella extract dose 540 mg / kg bw + repeatedly heated cooking oil as much as 2.1 ml / kg bw), and treatment group dose II (fed with standard diet + administered by red rosella extract dose 810 mg / kg bw + repeatedly heated cooking oil as much as 2.1 ml / kg bw). Analysis of data using statistical test One Way ANOVA and Tukey HSD (Î± = 0.05).Results: There were significant differences (p = 0.000) between groups. Red rosella extract treatment group dose 810 mg / kg bw and 540 mg / kg bw were significantly different from the positive control (p = 0.000). Red rosella extract group dose 540 mg / kg bw was significantly different from the negative control (p = 0.000). Red rosella extract group dosage of 810 mg / kg bw was not differ significantly from the control group (p = 0.171).Conclusion: The red rosellaâs petals extract dose of 810 mg / kg bw and dose of 540 mg / kg bw were able to prevent oxidative stress. Optimal deose of red rosella petals extract dose of 810 mg / kg bw was the most effective, because the higher antioxidant activity (67.33%) at dose 810 mg / kg bw dose than 540 mg / kg bw.

PENGARUH EKSTRAK KELOPAK ROSELLA MERAH MENAIKKAN KADAR SUPEROKSIDA DISMUTASE (SOD) TIKUS WISTAR YANG DIBERI MINYAK JELANTAH Herdiani, Novera
MEDICA MAJAPAHIT Vol 8, No 1 (2016): MEDICA MAJAPAHIT
Publisher : SEKOLAH TINGGI KESEHATAN MAJAPAHIT MOJOKERTO

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Minyak jelantah yang sering digunakan berulang oleh masyarakat mempunyai ikatan asam lemak jenuh dan mengandung radikal bebas yang berbahaya bagi kesehatan. Tujuan penelitian ini menganalisis pengaruh pemberian ekstrak kelopak rosella merah terhadap kondisi stres oksidatif tikus wistar yang diberi minyak jelantah melalui pengujian SOD serum. Penelitian ini merupakan Â eksperimental laboratorium. Sampel penelitian ini berjumlah 24 ekor tikus yang dipilih secara random dan dibagi menjadi 4 kelompok yaitu kontrol negatif (normal), kontrol positif, Â perlakuan ekstrak kelopak rosella merah dosis 540 mg/kg bb, dan dosis 810 mg/kg bb. Data yang terkumpul kemudian dianalisis menggunakan uji statistik One Way ANOVA dan Tukey HSD (Î± = 0,05). Â Pemberian ekstrak kelopak rosella merah dosis 810 mg/kg bb dan dosis 540 mg/kg bb dapat meningkatkan kadar SOD serum tikus wistar yang diberi minyak jelantah. Dosis perlakuan yang paling efektif adalah kelompok perlakuan ekstrak kelopak rosella merah dosis 810 mg/kg bb.Kata Kunci : Rosella Merah, Antioksidan, NO, SOD, MDA, Minyak Jelantah

GAMBARAN HISTOPATOLOGI PARU TIKUS WISTAR SETELAH DIBERI PAPARAN ASAP ROKOK Herdiani, Novera; Putri, Endah Budi Permana
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.583

Abstract: Cigarette smoke is the main cause of lung obstruction. One of the obstructions in real that iscaused by cigarette smoke is oxidative stress. Oxidative stress trigger inflammation response occur andlung obstruction. Cigarette smoke able to cause lung histopathology changes like lungs obstruction onalveolus wall. Red dragon fruit extract tackle free radical then able to against the oxidative stress. Theobjective of this study to examines the image of rat lung histopathology under exposed cigarette smoke.Twenty four Wistar rats divided four groups: negative control, positive control, red dragon fruit extracttreatment of 7,2 g/200 g WB, and red dragon fruit extract10,8 g/200 g WB. Negative control only givenstandard feed. Positive control given standar feed and exposed 21 cigarette per day. Treatment groupgiven feed during 21 days. In the 22nd day rats be sacrificed, the lung taken out for observation andimage of rat lung histopathology changes by making lung organ histopathology preparationhematoxicillin Eosion (HE) staining and observed under magnification light microscope 400x. The endresult of the study indicate the finding of changes in lung histopathology such as obstruction level overthe lung tissue higher, alveolar macrophage covered alveoli after being exposed cigarette smoke. Groupwhich does not exposed cigarette smoke, lung alveolus macrophage in normal condition, there are noobstruction or alveolus macrophage occurred, its alveolar macrophage does no covering alveoli.Treatment group administered fruit dragon extract dose 10,8 g/200 g WB and dose 7,2 g/200 g WB seemalmost the same with negative control treatment. Conclusion of the research is cigarette smoke exposecan influence the number of alveolar macrophage on wistar rats. Suggestion very required furtherresearch on oxdative stress parameter.

EFEK ROSELLA MERAH KERING TERHADAP KADAR MDA SERUM TIKUS STRAIN WISTAR YANG DI PAPAR ASAP ROKOK Herdiani, Novera; Afridah, Wiwik
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 2 (2017): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i2.606

Abstract: Cigarette smoke contains free radicals. Currently the number of smokers in Indonesia arestill high. This study aims to analyze the effects of red rosella of dried on the prevention of theincrease of Malondialdehyde (MDA) serum of strain wistar rats exposed to cigarette smoke. Thetotal sample of 24 male rats and divided into four groups: negative control, positive control, treatment of red rosella on dried dose 540 mg/bw, and red rosella on dried dose 810 mg/bw. Negativecontrol only given with standard feed. Positive control given by standard feed and exposed to 2cigarettes a day. Treatment group were feed by standard and red rosella of dried in the morning andexposed to 2 cigarettes after that. This study was conducted for 21 days. At the end of the study,blood serum was analyzed to determine MDA. The results of the study of MDA serum test isanalyzed with One Way ANOVA and followed by Tukey LSD test at 5% level. The giving of redrosella on dried dose 540 mg/bw and red rosella on dried dose 810 mg/bw can significantly preventthe increase of MDA serum in strain wistar rats exposed to cigarette smoke.

SOSIALISASI JAJANAN SEHAT SEBAGAI UPAYA PERBAIKAN STATUS GIZI PADA ANAK SEKOLAH DASAR DI SD MIFTAKHUL ULUM RUNGKUT SURABAYA Adriansyah, Agus Aan; Herdiani, Novera; Wijaya, Satriya
JURNAL PENGEMBANGAN KOMUNITAS Vol 1 No 1 (2017): July
Publisher : JURNAL PENGEMBANGAN KOMUNITAS

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Jajanan yang dijual pedagang keliling sering berada di depan lingkungan sekolah. Badan Pengawasan Makanan dan Minuman menyatakan terdapat 40% jajanan tidak layak dimakan. Kandungan boraks, serta formalin masih mendominasi kandungan zat-zat berbahaya pada jajanan anak-anak di sekolah-sekolah. Jajanan di sekolah memang beranekaragam dan lebih menarik minat daripada bekal yang dibawa dari rumah. Namun jajanan yang menarik tersebut justru miskin gizi dan jauh dari kata sehat. Berkaitan dengan fenomena tersebut, maka perlu adanya sosialisasi mengenai macam-macam, pengolahan, dan kelayakan konsumsi jajanan yang banyak dijual agar anak-anak dapat mengerti sehingga dapat memilih dan membedakan antar jajanan yang sehat dan tidak. Pengabdian masyarakat ini bertujuan untuk menambah pengetahuan dan kepedulian pada siswa untuk lebih memperhatikan berbagai macam jajanan yang dijual bebas demi menjaga status gizi pada masa anak-anak. Manfaat dari kegiatan ini adalah diharapkan dapat meningkatkan pengetahuan dan kepedulian seluruh siswa dalam memilih makanan atau jajanan yang sehat dan bergizi guna pendukung perkembangan generasi muda penerus bangsa yang dapat memajukan bangsa. Kegiatan intervensi yang dilakukan dengan dua metode yakni pelaksanaan sosialisasi perilaku bahaya membeli jajanan sembarangan di lingkungan SD Miftakhul Ulum Surabaya dan melakukan demo bagimana cara membuat jajanan yang sehat, bergizi, dan baik untuk perkembangan dan pertumbuhan anak. Kegiatanintervensi yang dilakukan disertai dengan pemberian pretest dan posttest. Sedangkan untuk memberikan pengetahuan kepada orangtua tentang informasi jajanan sehat, setiap siswa diberi brosur agar orangtua juga ikut mengawasi anaknya agar tidak membiarkan anak membeli jajan sembarangan. Di akhir kegiatan, setiap peserta melakukan kegiatan pengukuran tinggi dan berat badan untuk melihat status gizi mereka. Sasaran sosialisasi jajanan sehat adalah siswa SD Miftakhul Ulum Surabaya kelas 6A, 6B dan 6C secara langsung, serta guru maupun kepala sekolah secara tidak langsung. Hasil yang diperoleh pada kegiatan pengabdian masyarakat ini adalah peserta sosialisasi jajanan sehat merupakan siswa/siswi kelas 6 SD Miftakhul Ulum Surabaya dengan jumlah keseluruhan adalah 81 siswa/siswi. Sebagian besar merupakan siswa/siswi yang berusia 12 tahun (56,80%), sebagian besar berjenis kelamin laki-laki (55,60%). Peserta paling banyak adalah peserta dengan tinggi badan 130-140 cm (37,00%), dan berat badan 31-40 kg (46,90%). Berdasarkan penilaian BMI sebagian besar memiliki berat badan yang rendah (56,80%). Hasil evaluasi menurut penilaian pre test dan post test diketahui sebagian besar memiliki pengetahuan yang tetap (58,00%). Anak laki-laki lebih memiliki masalah pada status gizinya. Anak laki-laki sering mengalami berat badan rendah dan juga mengalami berat badan berlebih daripada anak perempuan. BMI anak laki-laki pada masa pra-sekolah menurun dan sejalan dengan bertambahnya usia maka BMI nya meningkat. Apapun jenis kelamin seseorang, bila dia masih produktif, berpendidikan, atau berpengalaman maka dia akan cenderung mempunyai tingkat pengetahuan yang tinggi. Rata-rata nilai evaluasi posttest lebih baik daripada pretest. Hal ini menandakan adanya efektivitas sosialisasi dalam meningkatkan pengetahuan.

PELATIHAN PEMBUATAN BEKAL SEHAT SECARA MANDIRIBAGI ANAK USIA SEKOLAH DI SDN MARGOREJO V SURABAYA Handayani, Dwi; Herdiani, Novera; Ayu, Friska
JURNAL PENGEMBANGAN KOMUNITAS Vol 2 No 1 (2018): August
Publisher : JURNAL PENGEMBANGAN KOMUNITAS

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Keamanan pangan jajanan berperan penting dalam pertumbuhan dan perkembangan anak sekolah. Kondisi lingkunganSDN Margorejo V Surabayabanyak terdapat penjual jajanandengan kualitas produk olahannya yang kurang baik. Selain itu masih sedikit anak sekolah yang membawa bekal sendiri dari rumah. Oleh sebab itu, perlu adanya penyuluhan tentang pemilihan jajanan sehat dan pelatihan pembuatan bekal sehat secara mandiri kepada siswa sekolah dasar. Kegiatan ini bertujuan menambahpengetahuan dan meningkatkan partisipasi siswa untuk menyediakan bekal sehat secara mandiri. Kegiatan dalam pengabdian masyarakat, yaitu pengukuran pengetahuan sebelum dan sesuda intervensi (pre-post test). Intervensi berupa penyuluhan jajanan. Hasil penilaian pengetahuan peserta sosialisasi (sebelum-sesudah) diketahui sebagian besar para peserta mengalami peningkatan pengetahuan mengenai jajanan sehat (56,1%). Setelah itu dilakukan pelatihan pembuatan bekal sehat dan pemberian buku resep menu bekal sehat kepada orang tua. Sebagian besar siswa (89,0%) menyukai metode praktik langsung, karena lebih mudah dipahami dan berkeinginan mencoba membuat bekal sehat bersama orang tuanya di rumah. Pihak sekolah perlu mendukung gerakan membawa bekal sehat melalui kebijakan/peraturan dan pemenuhan fasilitas kantin sehat. Kegiatan tersebut juga perlu didukung oleh partisipasi orang tua.

GAMBARAN STATUS GIZI ANAK KELAS VI DI SEKOLAH DASAR MIFTAKHUL ULUM SURABAYA Herdiani, Novera; Afridah, Wiwik
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 1 (2018): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i1.609

Abstract: Background, nutritional status is a description of balance between the need of nutrientsfor keeping a good life, to maintenance normal body function also energy production in one sideand the consumption of nutrients in the other. Children in elementary school are the best target forimprovement of community nutrition because in the childhood the function of the brain organbegan to form so the development of intelligence is quite rapid. Lack of nutritional intake inchildren can inhibit the physical growth and thinking ability in children and subsequently reduce inlearning interest. Therefore the nutritional status of the children must detect immediately to carryout the preventive measurements. Objective, the purpose of this study is to know the nutritionalstatus of children at grade VI in elementary school Miftakhul Ulum Surabaya based on height andweight. Methods, this study is a quantitative descriptive using survey method, weighting indexinstrument by height in children aged 6?17 years old from Health Department in 2011. This studyused the measurement of body weight and height. Subjects of this study were all students at grade VIin elementary school Miftakhul Ulum Surabaya, which amount 81 children. Data collecting techniques use anthropometric measurements which include measurement of body weight and heightthen calculated base of data analysis techniques using quantitative descriptive with percentage.Result, study results showed most of the students were 12 years old (56.80%), mostly male (55.60%).most of them have body height 130?140 cm (37.00%), and body weight 31?40 kg (46,90%). Malechildren have more problems with their nutritional status (51.10%). Male children much oftenhave underweight and over weight (13.30%) than girls. By the increasing their age, their BMI willbe normal category (100%). By the age of 13 and 14 years old, the children will not have underweight (0%). Conclusion, based on the nutritional status of all children at grade VI, it can beconcluded that the nutritional status of children at grade VI in elementary school Miftakhul UlumSurabaya is in underweight category (very thin and lean) with percentage 56.80%. While the normal weight percentage 32.10%, and over weight (fat and obesity) with percentage 11.10%.

PENGARUH ANTIOKSIDAN EKSTRAK BUAH NAGA MERAH TERHADAP SUPEROKSIDA DISMUTASE TIKUS YANG DIPAPAR ASAP ROKOK Herdiani, Novera; Permana Putri, Endah Budi
Jurnal Nutrire Diaita (Ilmu Gizi) Vol 10, No 02 (2018): NUTRIRE DIAITA
Publisher : Lembaga Penerbitan Unversitas Esa Unggul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47007/nut.v10i02.2540

vAsap rokok mengandung senyawa radikal bebas yang akan menyebabkan stres oksidatif. Ekstrak buah naga merah dapat menangkal radikal bebas. Penelitian ini bertujuan untuk menganalisis aktivitas antioksidan ekstrak buah naga merah dan Superoksida Dismutase tikus dipapar asap rokok. Penelitian ini eksperimental laboratorium, 24 ekor tikus wistar dibagi menjadi 4 kelompok : kontrol negatif, kontrol positif, perlakuan ekstrak buah naga merah 7,2 g/200 g BB dan 10,8 g/200 g BB. Kontrol negatif hanya diberi pakan standar. Kontrol positif diberi pakan standar dan dipapar 2 rokok per hari. Kelompok perlakuan diberi pakan standar dan ekstrak buah naga merah di pagi hari dan setelah itu dipapar 2 rokok. Masing-masing kelompok terdiri dari 6 ekor tikus. Penelitian ini dilakukan selama 21 hari. Data dianalisis menggunakan uji statistik One Way ANOVA dan Tukey HSD (Î±=0,05). Hasil penelitian menunjukkan bahwa ekstrak buah naga merah mengandung antioksidan 16,181 ppm dan Superoksida dismutase kelompok positif berbeda nyata dengan semua kelompok nilai signifikansi p = 0,000 < 0,05. Kelompok pemberian ekstrak buah naga merah dosis 10,8 g/200 g BB, tidak berbeda nyata dengan dosis 7,2 g/200 g BB dan kontrol negatif, nilai signifikansi ekstrak buah naga merah dosis 7,2 g/200 g BB yaitu p = 0,997 > 0,05 dan kontrol negatif yaitu p = 0,231 > 0,05. Kesimpulan penelitian bahwa pemberian ekstrak buah naga merah dosis 10,8 g/200 g BB dan 7,2 g/200 g BB mengandung antioksidan dan mampu mencegah terjadinya stres oksidatif ditandai peningkatan Superoksida Dismutase tikus dipapar asap rokok. Saran perlu dilakukan penelitian lebih lanjut parameter stres oksidatif.Â Kata kunci : Rokok, Superoksida Dismutase, tikus, buah naga merah

Literature Review: Faktor Sanitasi Kapal dengan Keberadaan Vektor di Kapal Rofiatul Asrifah; Herdiani, Novera
KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat Vol 7 No 1 (2021): June
Publisher : Universitas Widya Gama Mahakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24903/kujkm.v7i1.1130

Background: Ship are related to public health because they allow the spread of disease due to public health risk factors, one of which is the presence of vectors that can trigger disease exchange in human. The existence of vectors on board is caused by poor sanitation such as bad hygiene, inadequate lighting and ventilation, bad food storage, and scattered garbage that is not properly disposed of. Objectives: This literature review aims to determine the relationship between ship sanitation factors and the presence of vectors on ship Research Metodes: This study use the literature review method by searching for journals on the google scholar database and one search (2010-2020). The keyword used are "ship sanitation with vector presence", "ship sanitation and presence of vectors" and "ship and vector sanitation". Results: The result obtained on google scholar 150 articles and one search 16 articles where only 11 articles match this study. The result of this study, unqualified ship compartments namely kitchen and warehouse, due to ineligible hygiene, do not have adequate trash cans, and are free of insects and rat. The presence of cockroach vectors tends to be found on passenger ships and the presence of mosquito and mouse vectors tends to be found on cargo ship. Conclusion: The conclusion in this study is that ship sanitation factors are related to the existence of vectors. The advice given is to increase routine ship sanitation checks by the Port Health Office officers. Keywords: Ship, The Existence Of Vector, Sanitation

HUBUNGAN PENGETAHUAN, TINDAKAN MAKAN IBU HAMIL DAN STATUS GIZI IBU Herdiani, Novera; Afridah, Wiwik
Jurnal Nutrire Diaita (Ilmu Gizi) Vol 9, No 01 (2017): NUTRIRE DIAITA
Publisher : Lembaga Penerbitan Unversitas Esa Unggul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47007/nut.v9i01.1722

Nutritional problems is one of major public health problem which indirectly may elevate the risk for maternal and child mortality. The problem is preventable, and one of the risk factors is maternal eating behavior. The role of health professionals to provide nutritional counseling and monitor the pregnant womenâ€™s nutritional status is necessary for pregnant women in order that they want to behave and act to follow norms of nutrition and prevent complications as early as possible. The purpose of this study was to determine the relationship between the eating behavior of pregnant women and maternal nutritional status. The study design was cross-sectional, the sample was 42 pregnant women which selected by simple random sampling. The independent variable is the eating behavior which comprised from knowledge, and action while dependent variable is the maternal nutritional status based on body mass index. Chi square was performed to test the association with significance level of p ï‚£ 0.05. The results showed significant relationship between nutrition knowledge (p = 0.014), nutrition actions (p = 0.014) and maternal nutritional status, respectively. It is important to promote nutrition education among pregnant women to improve their nutritional status which in long term prevent maternal and infant mortality. Keywords: maternal behavior, nutrition education, nutritional status

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