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All Journal Alotrop Jurnal Pendidikan dan Ilmu Kimia ASIAN JOURNAL FOR POVERTY STUDIES (AJPS) Triadik Jurnal Laot Ilmu Kelautan Jurnal Metaedukasi : Jurnal Ilmiah Pendidikan Dulang: Jurnal Pengabdian Kepada Masyarakat Andromeda: Jurnal Pengabdian Masyarakat Rafflesia
Hermansyah Amir, Hermansyah
Faculty of Education, University of Bengkulu Bengkulu, Jl. W.R. Supratman, Kandang Limun, Bengkulu 38371A, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Education Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mathematics Physics Social Sciences Transportation Other

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THE POTENTIAL USE OF Phaleria macrocarpa LEAVES EXTRACT AS AN ALTERNATIVE DRUG FOR BREAST CANCER AMONG WOMEN LIVING IN POVERTY Amir, Hermansyah; Murcitro, Bambang Gonggo; Ahmad, Ahmad Shamsudin; Kassim, Murni Nur Islamiah
ASIAN JOURNAL FOR POVERTY STUDIES (AJPS) Vol 3, No 2 (2017)
Publisher : Regional Network on Poverty Eradication

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cancer is recognized as global threat to human development and it was estimated that in 2030 there will be 22.2 million new cases of cancer and 12.7 million cancer-related deaths worldwide. Herbal medicine plant till this day all over in the word is still the main source and one of the most important fields of traditional medicine agents to fight breast cancer. The usage of plants is still important because has its own beaviour advantages such as low toxicity, easy to get, cheap and has less side effect if it is used in a right. One of this plant it has been used as a traditional medicine is a Phaleria macrocarpa (Scheff) Boerl) also known as Mahkota Dewa from Papua island. It has been used traditionally for treatment of cancers in Indonesia and also to cure many diseases. The therapeutic effect of Phaleria macrocarpa (Scheff) Boerl, is related to the its bioactive compounds contents. There are many reported compounds from Phaleria macrocarpa (Scheff) Boerl, which are found, reported and published such as Icariside, phalerin, mangiferin, gallic acid, 29-Norcucurbitacin, gentiobioside and glucoside. All compounds reported above have already published as anticancer agents,where anticancer activity were detected and showed against Hela cells, leukemia cells, cervical cancer, breast cancer, and L1210 cells. Research on Phaleria macrocarpa (Scheff.) Boerl fruit and leaves merit have been done and published, however, there are very limited research on linked correlation between the concentration of compounds and its the cytotoxicity  level. Because of that, research about correlation level of Phaleria macrocarpa (Scheff) Boerl leaves extract still need to investigate to find the relationship between them in the goal to investigate alternative low cost herbal medicine agents to fight breast cancer especially useful for low income people, thus, information about Phaleria macrocarpa (Scheff.) Boerl.Leaves became more complete. Cytotoxicity properties of samples against breast cancer cell lines was performed by using the MTT assay against MCF-7 cell line. The correlation between concentration of crude and cytotoxic activity was interpreted by statistical analyses. The study showed that Phaleria macrocarpa (Scheff) Boerl.) leaves extracts showed cytoxicity activity against breast cancer MCF7 cell lines. Correlation between concentration of extract and cytotoxicity property (absorbance value) were founded in weak relationship (R = -0.37181). It could be effect of many different compounds in the Phaleria macrocarpa (Scheff) Boerl.) leaves methanol extracts may cause the pharmacological interactions, so lower or higher concentration will be antagonistic effect on absorbance or cell viability.Further study on its mechanism pathway on revealing against breast cancer could be explored. Furthermore, the natural product derived from Phaleria macrocarpa (Scheff) Boerl.) leaves extracts have potential use in cheap alternative agents against breast cancer
PENGEMBANGAN E-LKPD BERBASIS GUIDED DISCOVERY LEARNING PADA MATERI LAJU REAKSI Nadera Beka Adenolira; Amir, Hermansyah; Elvinawati
ALOTROP Vol. 7 No. 2 (2023): Alotrop 2023
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v7i2.30766

Abstract

Abstract This study aims to develop an e-LKPD based on Guided Discovery Learning and to determine the feasibility and student response to the e-LKPD. The development model used is the ADDIE model (analysis, design, development, implementation, evaluation) which is limited only to the development stage in the form of student response testing. The research was conducted from June to March 2023 at Bengkulu 1 Public High School. The research sample was taken by purposive sampling technique, namely class XI IPA 4, totaling 28 people for small group trials. The research instruments were interview sheets, student needs questionnaires, validation sheets, and student response questionnaire sheets. The resulting data consists of qualitative data in the form of suggestions from the validator and students as well as quantitative data on the results of validation sheets and student response questionnaires. Validation sheets and student response questionnaires use a Likert scale. The results showed that the chemical e-LKPD based on Guided Discovery Learning was declared very feasible by media and material experts with a media aspect percentage of 93.57% and a material aspect of 89.12%. Student responses to the e-LKPD were in the very good category with an average percentage of 91.13%, from the results of the study it could be concluded that the chemistry e-LKPD on Guided Discovery Learning-based reaction rates was very suitable for use as teaching materials. Keywords: e-LKPD; development; Guided Discovery Learning
PENGEMBANGAN E-MODUL KIMIA BERBASIS INTRODUCTION, CONNECT, APPLY, REFLECT, EXTEND (ICARE) PADA MATERI REAKSI REDOKS Nengsih, Ersa Agusti; Amir, Hermansyah; Handayani, Dewi
ALOTROP Vol. 7 No. 2 (2023): Alotrop 2023
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v7i2.31004

Abstract

This study is a research and development of ICARE-based chemistry e-modules that aims to determine the feasibility of e-modules, student responses, and improvement of student learning outcomes. The development model used is analysis, design, development, implementation, evaluation (ADDIE). The research was conducted at SMA Negeri 2 Seluma from January to August 2022. The subjects of this study were X IPA 2 and X IPA 3 students in the 2022/2023 school year who were selected based on simple random sampling techniques with a population of 3 classes, which were then tested for normality and homogeneity so that normal and homogeneous classes were obtained, namely X IPA 2 class for small group tests and X IPA 3 for large group tests. The instruments in this study were interview sheets, validation sheets, student response questionnaires, and tests. From the results obtained (1) ICARE-based chemistry e-modules were declared very feasible by media and material experts with a percentage of 98.88% media aspects and 91.25% material aspects, (2) Student responses to ICARE-based chemistry e-modules were in the very good category with an average percentage of 90.23%, and (3) After using ICARE-based chemistry e-modules on redox reaction material, there has been an increase in student learning outcomes as measured by an average N-gain score of 0.69 on moderate criteria. The results of the development of ICARE-based chemistry e-modules are very feasible to use in the learning process and proven to improve student learning outcomes. Keywords: e-module, development, ICARE, learning outcomes
PERBANDINGAN AKTIVITAS DAN HASIL BELAJAR MENGGUNAKAN MODEL PEMBELAJARAN SOMATIS AUDITORI VISUAL INTELEKTUAL (SAVI) BERBANTUAN BAHAN AJAR BERBASIS ANDROID DENGAN PRAKTIKUM Kartika Wahyuni; Amir, Hermansyah; Sura Menda Ginting
ALOTROP Vol. 8 No. 1 (2024): Penelitian Kimia dan Pembelajaran Kimia
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v8i1.34440

Abstract

This study aims to determine the differences in the activities and learning outcomes of students who apply the somatic, auditory, visual, intellectual (SAVI) learning model assisted by android-based teaching materials and practicum. This study uses a quasi-method with research samples of experimental class I used android-based teaching materials and experimental class II applying practicum. The method of data collection was carried out by conducting tests in measuring learning outcomes while the observation sheet of student activities in measuring learning activities. The results of observing the learning activities of students in the experimental class 1 and 2, respectively, are 69% and 74%, both in the active criteria. The cognitive learning outcomes of experimental class 1 and 2 students are 75.76 and 79.61, both in good criteria. There is a significant difference between learning activities and student learning outcomes who are taught by the application of the SAVI learning model assisted by android-based teaching materials and practicum. The results of the study can be concluded that in general the activities and learning outcomes of students with the application of the SAVI learning model with practicum are higher than those with the help of android-based teaching materials.
The Anticancer Potency of Pandanus odoratissimus Extracts In Human Breast Cancer (MCF-7) Cell Line Andriani, Yosie; Yahya, Rodhiyah; Gazali, Mohamad; Amir, Hermansyah; Subhan, Beginer
Jurnal Laot Ilmu Kelautan Vol 6, No 1 (2024): Jurnal Laot Ilmu Kelautan
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/jlik.v6i1.9275

Abstract

The development of novel chemical entities, novel pharmaceuticals, and novel drug leads frequently involves the use of natural sources. One of the most well-known plants, Pandanus odoratissimus (Pandanaceae), is native to Malaysia and has long been used in Ayurvedic medicine to treat a variety of illnesses. The purpose of this study is to determine P odoratissimus's antioxidant and anticancer properties against MCF-7 human breast cancer cell lines. The 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity was used to assess antioxidant activity, and among the other extracts, core exhibited the highest antioxidant value. An MTT assay was used to assess the effects of plant components on MCF-7 cell lines (3-(4, 5-dimethylthiazolyl)-2, 5-diphenyl-tetrazolium bromide). The concentration of samples was shown to considerably boost the antioxidant activities in P. odoratissimus extracts. Our findings demonstrated that, after receiving treatment for 72 hours, sample treated cancer cells experienced a decline in cell viability. The IC50 value of 88.00 mg/ml indicates that the extracts have a poor cytotoxic impact and have no promise as anticancer agents against MCF-7, which is why it’s killing efficiency in cancer cells is regarded as lower.
Penerapan Model Pembelajaran Problem Based Learning Berbantuan Media Virtual Lab untuk Meningkatkan Minat dan Hasil Belajar Kimia Siswa Kelas XI MIPA 5 SMAN 5 Kota Bengkulu Adriansyah, Renaldi; Amir, Hermansyah; Karlisa, Ice Dwi
TRIADIK Vol. 22 No. 1: April 2023
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/triadik.v22i1.33549

Abstract

Abstrak Penelitian ini merupakan penelitian tindakan kelas dengan tujuan untuk meningkatkan minat belajar dan hasil belajar kimia peserta didik kelas XI MIPA 5 SMA Negeri 5 kota Bengkulu pada materi larutan penyangga. Penelitian tindakan kelas ini dilaksanakan dengan menggunakan model Problem Based Learning (PBL) dengan pendekatan etnosains dan bantuan multimedia virtual lab. Penelitian ini dilakukan sebanyak dua siklus dengan empat tahapan yaitu perencanaan, pelaksanaan, observasi dan refleksi. Subjek penelitian ini adalah peserta didik kelas XI MIPA 5 SMAN 5 Kota Bengkulu yang berjumlah 37 peserta didik yang terdiri atas 29 perempuan dan 8 laki - laki. Pengumpulan data dilakukan dengan observasi, penyebaran angket, dan tes. Data yang diperoleh kemudian dianalisis dengan menggunakan teknik analisa kuantitatif sederhana yaitu analisis hasil belajar peserta didik, analisis angket minat belajar peserta didik, dan analisis hasil observasi aktivitas guru dan peserta didik. Hasil penelitian yang telah dilakukan menunjukkan bahwa rata - rata persentase ketuntasan hasil belajar peserta didik pada siklus I sebesar 75% meningkat menjadi 89% pada siklus II. Sedangkan persentase minat belajar peserta didik pada siklus I sebesar 73% meningkat menjadi 86% pada siklus II. Berdasarkan hasil penelitian ini maka dapat disimpulkan bahwa penerapan model Problem Based Learning (PBL) dengan bantuan multimedia virtual lab dapat meningkatkan hasil belajar dan minat belajar kimia peserta didik kelas XI MIPA 5 SMA Negeri 5 Kota Bengkulu pada materi larutan penyangga.
Peningkatan Hasil Belajar Peserta Didik pada Materi Larutan Penyangga melalui Model Pembelajaran Problem Based Learning Indriyani, Rika; Amir, Hermansyah; Karlisa, Ice Dwi
TRIADIK Vol. 22 No. 2: Oktober 2023
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/triadik.v22i2.33616

Abstract

Abstrak Penelitian ini bertujuan untuk meningkatkan pencapaian hasil belajar peserta didik dalam materi larutan penyangga di SMA Negeri 5 Kota Bengkulu menggunakan model pembelajaran Problem Based Learning (PBL). Penelitian ini dilakukan dalam bentuk Penelitian Tindakan Kelas (PTK) dengan menerapkan model Kemmis dan McTaggart, yang melibatkan tahap perencanaan, tindakan, observasi, dan refleksi pada setiap siklusnya. Penelitian ini terdiri dari 2 siklus, dengan setiap siklus terdiri dari 2 pertemuan. Sampel penelitian terdiri dari 38 peserta didik kelas XI MIPA 1 SMA Negeri 5 Kota Bengkulu pada tahun ajaran 2022/2023. Instrumen yang digunakan dalam penelitian ini meliputi instrumen observasi proses pembelajaran dan instrumen post-test. Hasil penelitian menunjukkan adanya peningkatan dalam pencapaian hasil belajar klasikal peserta didik sebesar 23,3%. Pada siklus I, persentase hasil belajar klasikal mencapai 63,1%, kemudian meningkat menjadi 86,4% pada siklus II.
SOSIALISASI PENGOLAHAN MINYAK JELANTAH MENJADI SABUN CUCI Amir, Hermansyah; Hersy Khosyati; Intan Putri Utami; Nining Febri Busraningsih; Novri Hemdi Saputra; Okta Rahmadany Arkanshi; Perti Ulandari; Ranti Oktiandi; Sekar Chairunisa Regianti; Shelvyna Woulandari; Yenni Anggriani
Andromeda: Jurnal Pengabdian Masyarakat Rafflesia Vol. 4 No. 1 (2024): ANDROMEDA: Jurnal Pengabdian Masyarakat Rafflesia
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/andromeda.v4i1.34922

Abstract

Kegiatan pengabdian kepada Masyarakat dilakukan di JL. Melinjo RT 01 RW.01 Kel. Kandang Kota Bengkulu, dengan peserta para ibu-ibu PKK. Kegiatan ini bertujuan untuk memberikan informasi tentang pemanfaatan limbah minyak jelantah sebagai bahan baku produk sabun yang bernilai dan episien untuk rumah tangga. Kegiatan dilakukan melalui sosialisai pembuatan produk sabun. Kegiatan diikuti oleh 20 orang ibu-ibu PKK RT 01 RW.01 Kel. Kandang Kota Bengkulu  pada tanggal 27 April 2024  yang menunjukkan antusiasme terhadap sosialisasi yang ditampilkan. Diharapkan hasil sosialisasi yang dilakukan memberikan gambaran kepada masyarakat khususnya para ibu-ibu dilingkungan RT 01 RW.01 Kel. Kandang Kota Bengkulu untuk pengoptimalan limbah minyak jelantah yang ada . Selain itu, kegiatan ini dapat menjadi kegiatan  yang produktif dan memperdayakan masyarakat untuk mengolah dan memproduksi sabun dari limbah minyak jelantah serta diharapkan berdampak positif karena dapat memberikan alternative untuk menanggulangi penumpukan sampah dan pembuangan limbah yang tidak tepat, serta dapat membuka peluang usaha baru guna meningkatkan perekonomian masyarakat.
BIMBINGAN TEKNIS PENELITIAN TINDAKAN KELAS BAGI GURU MATEMATIKA DAN IPA DI SMAN 4 KOTA BENGKULU Dewi Handayani; Amida, Nadia; Amir, Hermansyah; Wiwit
Andromeda: Jurnal Pengabdian Masyarakat Rafflesia Vol. 4 No. 1 (2024): ANDROMEDA: Jurnal Pengabdian Masyarakat Rafflesia
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/andromeda.v4i1.35081

Abstract

Guru adalah komponen penting dalam menciptakan pembelajaran yang inovatif, kreatif dan menyenangkan di sekolah. Salah satu upaya menciptakan guru yang professional dan berkualitas yaitu dengan kemampuannya untuk meneliti yaitu Penelitian Tindakan Kelas (PTK). Observasi ke SMAN 4 Kota Bengkulu, masih ditemukan guru yang belum mengetahui prosedur, pembuatan proposal dan implementasi PTK di kelas. Kegiatan pengabdian ini ditujukan bagi guru- SMAN 4 Kota Bengkulu yang berjumlah 16 orang (khusus guru MIPA) dengan metode ceramah dan praktek langsung dalam pembuatan proposal PTK. Setelah dilakukan pelatihan pembuatan proposal PTK, peserta pengabdian memahami bahwa PTK sangat penting dalam meningkatkan kualitas pembelajaran. Peserta sangat antusias dalam mengikuti kegiatan bimbingan teknis pembuatan proposal PTK dan sebanyak 85% peserta berhasil membuat proposal PTK. Beberapa tahapan umum dari PTK diantaranya yaitu kegiatan perencanaan, pelaksanaan, pengamatan dan kegiatan refleksi untuk perbaikan di siklus berikutnya.
PELATIHAN PEMANFAATAN PLATFORM MERDEKA MENGAJAR (PMM) DALAM IMPLEMENTASI KURIKULUM MERDEKA BAGI GURU MIPA Handayani, Dewi; Amir, Hermansyah; Candra, I Nyoman; Alperi, Muzanip
Jurnal Pengabdian Masyarakat Polmanbabel Vol. 4 No. 02 (2024): DULANG : Jurnal Pengabdian Kepada Masyarakat
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33504/dulang.v4i02.340

Abstract

Observations carried out at SMAN 2 Rejang Lebong show that readiness to implement the independent curriculum and the use of the Platform Merdeka Mengajar (PMM) in its implementation is still lacking. So, it is necessary to assist in the use of PMM in implementing the independent curriculum at SMAN 2 Rejang Lebong. The aim of this service is to introduce the features in PMM for Mathematics and Science (MIPA) teachers at SMAN 2 Rejang Lebong. Providing knowledge and skills for MIPA teachers at SMAN 2 Rejang Lebong regarding the use of PMM in implementing the independent curriculum. The target of this activity is MIPA teachers at SMAN 2 Rejang Lebong. The total number of targets is around 22 people. Furthermore, participants who had received training directed teachers in other fields of study who had not been invited to this activity. The methods used in this activity are training and workshops, guided assignment work and evaluation monitoring at the final stage. Based on the results of the service that has been carried out, teachers are very enthusiastic about participating in the training. As many as 100% of teachers have successfully opened an account at PMM and 85% have utilized the features available at PMM.
Co-Authors Adriansyah, Renaldi Ahmad Shamsudin Ahmad, Ahmad Shamsudin Amida, Nadia Beginer Subhan Candra, I Nyoman Dewi Handayani Elvinawati Hartawan, Muhammad Gustian Hersy Khosyati Indriyani, Rika Intan Putri Utami Karlisa, Ice Dwi Kartika Wahyuni Krisna Dewi, Krisna Mohamad Gazali Murcitro, Bambang Gonggo Murni Nur Islamiah Kassim, Murni Nur Islamiah Muzanip Alperi, Muzanip Nadera Beka Adenolira Nengsih, Ersa Agusti Nining Febri Busraningsih Novri Hemdi Saputra Okta Rahmadany Arkanshi Perti Ulandari Ranti Oktiandi Sekar Chairunisa Regianti Shelvyna Woulandari Sura Menda Ginting Wiwit Yahya, Rodhiyah Yenni Anggriani Yosie Andriani