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POTENSI ANTIOKSIDAN INFUSA BUNGA TELANG (Clitoria ternatea), ROSELLA (Hibiscus sabdariffa) DAN DAUN STEVIA (Stevia rebaudiana) SEBAGAI ANTIDIABETES Melania Perwitasari; Sinta Nuriyah Awaliyah; Intan Kurnia Putri; Nofria Rizki Amalia Harahap; Ariska Deffy Anggarany; Reza Anindita; Maya Uzia Beandrade; Dede Dwi Nathalia
Jurnal Mitra Kesehatan Vol. 5 No. 2 (2023): Jurnal Mitra Kesehatan
Publisher : STIKes Mitra Keluarga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47522/jmk.v5i2.194

Abstract

Reactive Oxygen Species (ROS) can induce oxidation that caused aging and degenerative diseases such as Diabetic Mellitus. To prevent the incident of degenerative disease, antioxidant needed that found in many herbs, especially colored herbs. Butterfly pea, Rosella flower, and Stevia leaf known as herbs contains phenolic and flavonoid. This constituent are responsible as antioxidant activity. Many people consume the herbs by brewing with hot water as infused water. The purpose of this research is to determine antioxidant activity of infused Butterfly pea, Rosella flower, and Stevia leaf by FRAP method. This is non experiment method descriptive with dry herbs of Butterfly pea, Rosella flower, and Stevia leaf infused extract as sample. The research was conducted in September 2022-February 2023 at STIKes Mitra Keluarga Laboratory. The antioxidant activity is expressed as % FRAP activity. Based on the experiment, it knows that % FRAP activity of Butterfly pea, Rosella flower, and Stevia leaf consecutive 55,29% ± 0,0, 69,17% ± 0,12 , 61,55% ± 0,04.
Anti-Bacterial Activity of Etanolic Extract and Essential Oil of Basil (Ocimum sanctum) on Growth Staphylococcus aureus Salmonella thypii and Eschericia coli Melania Perwitasari; Reza Anindita; Maya Uzia Beandrade; Dede Dwi Nathalia; Wahyu Nuraini Hasmar; Intan Kurnia Putri
Jurnal ILMU DASAR Vol 24 No 2 (2023)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jid.v24i2.31367

Abstract

Antimicrobial resistance is one of the biggest health problems. Indonesia is a country with a positive high number of E. coli (71%) Extended Spectrum Beta Lactamase (ESBL) in the Asia Pacific. Many studies report that essential oils and extracts from several species of Ocimum have antimicrobial activity against gram-positive and negative bacteria. Antibacterial activity is related to active compounds contained in plants that are also affected by the place of growth, harvesting and post-harvesting. Research related to the activity of basil (Ocimum sanctum) that already exists does not provide complete and comprehensive data related to where to grow, harvest and post-harvest basil leaves. Basil leaves that have been set parameters for growth, harvest and post-harvest processes are extracted using maceration method with 70% etanol solvent and distilled to obtain essential oils (EO). Etanolic extract (EE) and EO were tested for their activity against Escherichia coli, Staphylococcus aureus and Salmonella thypii bacteria. The results showed that the basil leaves obtained from Margahayu sub-district, East Bekasi, had a dry simplicia yield of 12.8% ± 1.5, yield of EE 16.9% ± 1.6, EO content of 0.56%. The etanolic extract of basil leaves contains alkaloids, saponins, tannins, phenolics, flavonoids, glycosides, triterpenoids and steroids. The conclusion from the results of this study is the etanol extract and essential oils of basil leaves can inhibit the growth of bacteria, both basile leaves. The inhibition zone diameter is higher in gram positive bacteria (S. aureus) than gram negative bacteria (S. thypii and E. coli).