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Fraksinasi dan Identifikasi Ektrak Daun Mitragyna Speciosa Menggunakan Metode Kromatografi M.A. Hanny Ferry Fernanda; Mercyska Suryandari; Tri Puji Lestari Sudarwati
FARMASIS: Jurnal Sains Farmasi Vol 2 No 2 (2021): Farmasis : Jurnal Sains Farmasi
Publisher : Program Studi Farmasi Fakultas Sains Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v2i2.4072

Abstract

Background: Mitragyna Speciosa or better known as Kratom is a typical plant from the Putusibau area, West Kalimantan. The most widely used part of this plant is the leaves. The kratom plant contains alkaloids, flavonoids, phenols, terpenoids-steroids, triterpenoids, saponins, and tannins. Alkaloid content is the most dominant and has benefits in this plant so it is necessary to do fractionation and identification of secondary metabolites. Objective: To fractionate and identify secondary metabolites from Mitragyna Speciosa leaf extract. Methods: The fractionation method was carried out using Column Chromatography while for identification using Thin Layer Chromatography. Results: 80 fractions were obtained from the column chromatography results, while the results of identification using thin layer chromatography showed that only the 2nd and 3rd fractions were obtained. The second fraction has two spots with Rf values of 0.51 and 0.73 and in the third fraction there are three spots with Rf values of 0.21; 0.52, and 0.74. Conclusion: Fractionation and identification by chromatographic method can be used as initial screening for secondary metabolite content in Mitragyna Speciosa leaf extract.
PENINGKATAN PENGETAHUAN MASYARAKAT MENGENAI PERKEMBANGAN DAN PENYEBARAN DBD Tri Puji Lestari Sudarwati; M.A Hanny Ferry Fernanda; Mercyska Suryandari
Jurnal Abdi Masyarakat Kita Vol 1 No 1 (2021): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1176.178 KB) | DOI: 10.33759/asta.v1i1.92

Abstract

This community service event was aimed to elevate the knowledge of local society regarding the current update of Aedes aegypti mosquito as a vector of Dengue Hemorrhagic Fever (DHF). Hence, it raised awareness of their role in breaking the disease transmission. Involving students as supporting team, this activity was carried out at Jemur Gayungan RW 01 by giving public counselling and mentoring for the larvae surveyor cadre (Jumantik). Abdimas, which has been done, adds to the knowledge of jumantik cadres about the proliferation and spread of dengue, so that jumantik cadres not only observe their environment but can also take action to break the chain of dengue spread.
SOSIALISASI PEMILIHAN PERALATAN MAKAN DAN MINUM BERBAHAN MELAMIN YANG AMAN DI POSYANDU LANSIA KETINTANG SURABAYA Surahmaida Surahmaida; Mercyska Suryandari; Meyke Herina Syafitri; Ninik Mas Ulfa
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 3 No. 3 (2022): Volume 3 Nomor 3 Tahun 2022
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v3i3.9424

Abstract

Peralatan makan dan minum dari melamin banyak digunakan di berbagai kalangan masyarakat karena tidak mudah pecah, awet, harganya terjangkau dan umumnya memiliki desain dengan warna dan motif yang menarik. Namun, peralatan makan minum bermelamin dianggap berpotensi membahayakan kesehatan. Hal ini dikarenakan masyarakat cenderung memilih peralatan makan minum yang harganya murah tanpa memperhatikan label keamanan produk dan perawatan penggunaan produk. Adanya kegiatan Pengabdian pada Masyarakat ini bertujuan untuk memberikan pengetahuan kepada masyarakat mengenai pengertian melamin, keunggulan produk peralatan makan dan minum bermelamin, bahaya melamin bagi tubuh, pentingnya membaca kode produk dan tips aman penggunaan peralatan makan bermelamin. Hasil dari kegiatan pengabdian masyarakat ini agar masyarakat memahami dan mulai menerapkan budaya teliti sebelum membeli dan menggunakan produk peralatan makan dan minum dari bahan melamin yang benar sebagai upaya menjaga kesehatan keluarga.
Identification of Secondary Metabolites of Onion Peels Extract (Allium cepa L.) of Various Solvent: Identifikasi Senyawa metabolit Sekunder Ekstrak Kulit Bawang Merah (Allium cepa L.) dari Berbagai Macam Pelarut Mercyska Suryandari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 7 No. 2 (2022): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v7i2.289

Abstract

Onion peels (Allium cepa L.) is often disposed of without being used and ends up as waste in markets that can pollute the environment. Onion peels can potentially be developed for treatment as an anti-cancer because of its phytochemical compounds. Previous studies have shown that secondary metabolites found in onion peels using different solvents produce different secondary metabolites. So the purpose of this study was to find out the secondary metabolite compounds from onion peels extract (Allium cepa L.) qualitatively when extracted using 5 different solvents. This research was conducted using a phytochemical screening method on the onion peels extract (Allium cepa L.). n-Hexane, Ethyl Acetate, Acetone, Ethanol 96%, and Chloroform were used in the maceration extraction method separately. The results showed that the yield value was 0.96%; 2.66%; 3.90%; 4.80%; 1.62%. The results showed that acetone, ethanol, and chloroform extracts of onion peels extract (Allium cepa L.) contained alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins. Meanwhile, the ethyl acetate extract of onion peels contains alkaloids, flavonoids, steroids, terpenoids, and tannins. Lastly, the n-hexane extract of the onion peels only contains steroids and terpenoids. So it can be concluded that secondary metabolites in onion peels extract contain alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins.
Antioxidan Activity from Methanol Extract of Kratom Leaves (Mitragyna speciosa) Maseration Result Using The DPPH Method: Aktivitas Antioksidan Ekstrak Metanol Daun Kratom (Mitragyna speciosa) Hasil Maserasi Menggunakan Metode DPPH Andhika Dwi Aristyawan; Anggi Ayu Windari; Mercyska Suryandari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 2 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i2.357

Abstract

Antioxidants are compounds that can prevent the formation of free radicals. Kratom is a typical plant from South Putussibau area, in West Kalimantan. The kratom plant contains alkaloids, triterpenoid-steroids, saponins, tannins and flavonoids. The main component of kratom leaves is an indole alkaloid that is efficacious as an antioxidant. The goal is to determine the antioxidant activity of kratom leaf extract (Mitragyna speciosa). The method used is the measurement of the reduced amount of DPPH from an antioxidant compound UV-Vis spectrophotometrically at a wavelength of 517nm using Vitamin C as a comparison. The extraction method used is maceration. The test was sampled 10 mg of kratom leaf extract (Mitragyna speciosa) with 10 ppm, 20 ppm, 30 ppm, 40 ppm, and 50ppm concentrations, then repeated 3 times. The results of the antioxidant activity of kratom leaves (Mitragyna speciosa) were expressed with IC50 values of 44,169 ± 0.5313 with an RSD value of 1.202%. Then it can be concluded that kratom leaf methanol extract (Mitragyna speciosa) has a very strong antioxidant activity with an IC50 value of 44,169 ± 0.5313 with an RSD value of 1.202%.
EDUKASI PENGENALAN GEJALA DIABETES MELLITUS PADA ANAK UNTUK MENINGKATKAN KEWASPADAAN TENTANG BAHAYA DIABETES PADA ANAK Eziah Ika Lubada; Meyke Herina Syafitri; Mercyska Suryandari; Rizky Darmawan
Jurnal Gembira: Pengabdian Kepada Masyarakat Vol 1 No 05 (2023): OKTOBER 2023
Publisher : Media Inovasi Pendidikan dan Publikasi

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Abstract

Diabetes Mellitus (DM) tidak hanya terjadi pada orang Dewasa tetapi dapat pula terjadi pada Anak. Insiden Diabetes Mellitus (DM) Tipe-1 pada anak di dunia dan Indonesia terus meningkat. Berdasarkan data Ikatan Dokter Anak Indonesia (IDAI), tercatat 1220 dengan DM tipe-1 pada tahun 2018. Kesadaran masyarakat dan tenaga kesehatan mengenai diabetes pada anak masih rendah, yang direfleksikan melalui tingginya angka anak yang terdiagnosis dengan DM    tipe-1 saat mengalami ketoasidosis diabetikum mencapai 71% pada tahun 2017 (Pulungan et al., 2019). Oleh karena itu, Dalam meningkatkan pemahaman ibu mengenai pentingnya waspada bahaya diabetes melitus pada anak, maka dilaksanakan Kegiatan Pengabdian pada Masyarakat dengan judul “Penyuluhan Edukasi Diabetes Mellitus Pada Anak Untuk Meningkatkan Kewaspadaan Tentang Bahaya Diabetes Pada Anak”, pada ibu-ibu warga RT 03 RW 07 Jalan Dukuh Kupang Gang Lebar Surabaya pada tanggal 27 Mei 2023. Sebelum penyuluhan dimulai, peserta diberi pre-test, lalu setelah penyuluhan selesai dilaksanakan peserta diberi post-test, hal ini dilakukan untuk menguji pemahaman peserta mengenai materi sebelum dan sesudah penyuluhan. Hasil dari pre-test dan post-test tersebut diuji statistic menggunakan uji t-berpasangan, hasilnya p-value = 0.03 < 0.05 dan rata-rata post-tets lebih tinggi dari pre-tets, sehingga ada peningkatan signifikan pemahaman peserta setelah penyuluhan tentang bahaya diabetes pada anak.
SKRINING FITOKIMIA EKSTRAK ETANOL 80% ROSEMARY (Rosmarinus officinalis L.) DENGAN METODE EKSTRAKSI DIGESTI Evi Priyatno; Mercyska Suryandari
Jurnal Komunitas Farmasi Nasional Vol. 2 No. 1 (2022): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

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Abstract

Rosemary (Rosmarinus officinalis L.) in the Lamiacea family is one of the herbal plants that has medicinal properties. Based on its potential benefits, a phytochemical screening study was conducted to determine the class of secondary metabolites contained in it and to test the ability of 80% ethanol for extracting secondary metabolites from rosemary extract using the digestion extraction method. The filtrate was then concentrated using a rotary evaporator and phytochemical screening tests were carried out by observing the presence of color changes, formation of precipitates, and the formation of stable foam using certain reagents. The results showed that the ethanol extract of 80% rosemary was positive for terpenoids, alkaloids, flavonoids, saponins, tannins, and polyphenols