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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN) Journal of Pharmaceutical and Sciences. Acta Holistica Pharmaciana
Viani Anggi
STIFA Pelita Mas Palu
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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ANALISIS KANDUNGAN HIDROKUINON DALAM KRIM RACIKAN PENCERAH WAJAH YANG BEREDAR DI PASAR MASOMBA KOTA PALU SULAWESI TENGAH DENGAN METODE KROMATOGRAFI LAPIS TIPIS (KLT) Viani Anggi
Acta Holistica Pharmaciana Vol 1 No 1 (2019): Acta Holistica Pharmaciana
Publisher : School of Pharmacy Mahaganesha (Sekolah Tinggi Farmasi Mahaganesha)

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Abstract

Telah dilakukan penelitian tentang analisis kandungan Hidrokuinon dalam krim racikan pencerah wajah yang beredar di pasar Masomba Kota Palu dengan metode kromatografi Lapis Tipis. penelitian ini bertujuan untuk mengetahui ada atau tidak kandungan Hidrokuinon yang terdapat dalam krim racikan tersebut dan untuk mengetahui berapa kandungan yang terdapat dalam krim racikan tersebut dengan metode kromatografi lapis tipis. Penelitian ini menggunakan pustaka metode ACM INO 03 dengan parameter identifikasi menggunakan metode kromatografi lapis tipis menggunakan 3 sampel krim racikan pencerah wajah yang beredar di pasar Masomba. Teknik analisis data yang digunakan untuk menganalisis krim racikan pemutih menggunakan kromatografi lapis tipis, selanjutnya setelah didapatkan hasil analisis data dilakukan teknik pengolahan data dengan membandingkan hasil kualitaf dan kuantitatif yang diperoleh dari BPOM kota Palu dengan standar PERMENKES RI No.445/menkes/per/v/1998 tentang standar kandungan Hidrokuinon dalam krim pencerah wajah. Hasil yang diperoleh dari penelitian kualitatif yaitu krim pencerah wajah yang beredar di kota Palu tidak mengandung Hidrokuinon,jumlah kandungan hidrokuinon pada krim pencerah wajah yang beredar di pasar masomba tidak mengandung hidrokuinon
Aktivitas Analgesik dan Antiinflamasi Nanoemulsi Ekstrak Etanol Rimpang Kunyit (Curcuma longa L.) secara In Vivo Recky Patala; Viani Anggi; Isna Paula; Nur Sakina
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.295

Abstract

Pain and Inflammation are our body's average protective measures. The presence of an inflammatory process is characterised by typical features, namely the appearance of redness, swelling in the area of inflammation, heat, and the onset of pain. One of the traditional plants widely obtained in Indonesia is Curcuma longa L. Curcuma longa L. contains flavonoid and curcumin compounds known to have analgesic and anti-inflammatory effects. The ethanol extract of Curcuma longa L. rhizome is formulated in nanoemulsion dosage form to reduce toxicity, improve drug distribution efficiency, and increase the bioavailability of drugs with low absorption. This study aims to determine the effect of the administration of nanoemulsion of ethanol extract of Curcuma longa L. at doses of 20 and 25 mg/kg bw on analgesic and anti-inflammatory activities carried out on male white rats of Wistar strain induced by 1% acetic acid and 1% carrageenan. Rats were divided into five groups (n=5), namely standard control (nanoemulsion without extract), positive control (mefenamic acid nanoemulsion for analgesic test and diclofenac sodium nanoemulsion for anti-inflammatory test), negative control (1% acetic acid nanoemulsion and 1% carrageenan nanoemulsion), P1 (extract nanoemulsion dose of 20 mg/kg bw), and P2 (extract nanoemulsion dose of 25 mg/kg bw). Furthermore, the number of writhing was measured from 5 to 60 minutes, and the leg volume changed from 1 to 6 hours. The results showed a decrease in the number of writhes with an increase in % Protection and significant inhibition of inflammation (p<0.05) in both doses of 20 mg/kg bw and 25 mg/kg bw with a per cent protection of 35.21% and a decrease in oedema volume by 64.79%. Nanoemulsion of Curcuma longa L. extract at doses of 20 and 25 mg/kg bw has activity as an analgesic and anti-inflammatory induced by 1% acetic acid and 1% carrageenan
Pelatihan Peningkatan Pengetahuan dan Keterampilan Masyarakat Dalam Menggunakan Daun Miana (plectranthus scutellarioides (l.) R.br.) Sebagai Tanaman Obat Viani Anggi; Utami Islamiati; Michele Anastasya P
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 5 No. 1 (2024): Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN)
Publisher : Sistem Informasi dan Teknologi (Sisfokomtek)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55338/jpkmn.v5i1.2669

Abstract

Daun miana memiliki ciri khas warna yang unik pada bagian daunnya dan memiliki banyak manfaat terutama pada bagian daunnya.  Penggunaan daun miana banyak digunakan untuk pengobatan herbal sebagai sumber alami dari tanaman dengan kandungan khas yang dimilikinya. Dari hasil survei kuesioner didapatkan bahwa 50% masyarakat umumnya sudah terbiasa menggunakan daun miana sebagai tanaman obat tradisional, namun untuk jumlah takaran dan cara penggunaan yang tepat masih belum dipahami dengan baik, untuk itu sangat dibutuhkan peningkatan pengetahuan dan keterampilan masyarakat untuk dapat menggunakan rebusan daun miana yang sesuai dan bermutu untuk digunakan sebagai terapi dalam pengobatan tradisional. Pengabdian ini dilakukan bertujuan untuk memberikan peningkatan pengetahuan dan keterampilan masyarakat tentang penerapan daun miana sebagai tanaman obat.  Tahapan pelaksanaan pengabdian ini yaitu pemberian edukasi dengan memberikan kuesioner kepada masyarakat dan dilanjutkan dengan pemaparan teori dan sesi tanya jawab dengan masyarakat. Hasil dari Kegiatan pengabdian kepada masyarakat memberikan ilmu pengetahuan tentang aplikasi rebusan daun miana, sehingga warga desa Sejahtera memiliki pengetahuan untuk pengolahan penggunaan daun miana sebagai tanaman obat dan peningkatan kesehatan warga Desa Sejahtera, Kecamatan Palolo Kabupaten Sigi dengan Pemeriksaan Kesehatan untuk penyakit degeneratif seperti Diabetes, asam urat, Tekanan darah dan kolesterol.
Anticancer Activity of Rosella Flowers (Hibiscus Sabdariffa l.) In HepG2 cells Viani Anggi; Recky Patala; Arfiah Arfiah; Niluh Puspita Dewi
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.6350

Abstract

The natural ingredients of rosella flowers have the potential as natural anti-cancer and chemopreventive agents, contain secondary metabolite compounds with cancer therapeutic mechanisms with inhibiting and killing cancer cells and their development through inhibition of apoptosis (cell death program) and in vitro inhibited cell flow. The study aims to identification of secondary metabolite compounds and also determine the cytotoxic activity of ethanol extract from the rosemary plant against HepG2 cancer cells. This study used by identification of secondary metabolite compounds of ethanol extract from the rosemary plant (Hibiscus sabdariffa L.) and the cytotoxicity test used with MTT assay on HepG2 liver cancer cells with a test concentration series of 12,5; 25; 50; 100; 200; 250; 500 and 1000 µg/ml. : The results showed the secondary metabolite compounds of rosella flowers have flavonoids, alkaloids, saponins and tannins and data of 50% cell growth inhibition activity, which was showed that rosella flower had IC50 values 629,919 μg/mL. The ethanol extract of rosella flowers have activity on HepG2 cells growth inhibition had considered moderately active anticancer activity
Enzymatic virgin coconut oil effect on urea and creatinine levels of hypercholesterolemia-diabetics induced Wistar male rats Niluh Puspita Dewi; Syafika Alaydrus; Nadila Nadila; Magfirah Magfirah; Joni Tandi; Viani Anggi; Nani Astria
Pharmaciana Vol 14, No 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.27489

Abstract

Coconut (Cocos nucifera) is an Indonesian commodity that has high economic value tall. Virgin Coconut Oil (VCO) is one of the processed coconut products whose selling value is very high, because The composition of VCO consists of medium-chain fatty acids that can maintain a healthy body and prevent various diseases. The process of making VCO used in This research is an enzymatic method using pineapple weevil as a bromelain enzyme. This study aims to determine the effect of enzymatic administration of VCO and an enzymatic dose of VCO which is effective in reducing urea and creatinine levels in hypercholesterolemic-diabetic male white rats (Rattus norvegicus). This study was an experimental laboratory with a modified pretest and posttest randomized controlled group design using 30 test animals which were divided into 6 treatment groups. Each group consisted of 5 test animals, namely normal control, negative control, and positive control, with doses of 0.2, 0.4, and 0.8 mL/kg BW. The data obtained were analyzed using a One Way Anova and non- parametric statistical test by Kruskal Wallis. test and followed by a further Mann Whitney test to determine differences between treatments. The results showed that enzymatic VCO at a dose of 0.8 mL/kg BW was an effective dose in reducing urea and creatinine levels with an average decrease of 17.40 mg/dL and 0.36 mg/dL. The novelty in this study showed that the enzymatic VCO had an effect on reducing urea and creatinine levels in diabetic hypercholesterolemic male white rats.
Co-Authors Arfiah Arfiah Isna Paula Joni Tandi, Joni Magfirah Magfirah Michele Anastasya P Nadila Nadila Nani Astria Niluh Puspita Dewi Niluh Puspita Dewi Nur Sakina Patala, Recky Recky Patala Syafika Alaydrus Utami Islamiati