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All Journal HAYATI Journal of Biosciences ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal farmasi UIN Alauddin Makassar
Arsul, Muhammad Ikhlas
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Formulation and Characterization of Edible Film with Concentration Various of Sodium Carboxymethyl Cellulose from Kepok Banana (Musa paradisiaca L.) Bark and Plasticizer Ningsi, Surya; Abbas, Nurfahima; Arsul, Muhammad Ikhlas
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 7 No. 1 (2024)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v7i1.45330

Abstract

Introduction: Bark of kepok banana (Musa paradisiaca L.) contains high cellulose that can be synthesized into sodium carboxymethyl cellulose (Na-CMC). Na-CMC can be used as a raw material for the preparation of edible film. Aims: The purpose of this study was to determine the concentration of sodium carboxymethyl cellulose from kepok banana bark combine with plasticizer to produce edible films with good characteristics and quality. Methodology: Edible films were made with varying concentrations of 6%, 10%, and 14% Na-CMC; 4% glycerol and 9% sorbitol as plasticizer. Edible films were made using casting method and characterized including organoleptic test, thickness, pH, water absorption, elongation, and tensile strength. Result: Edible film made is in the form of thin layer, transparent white in color, and odorless; thickness 0,10±0,01-0,38±0,01 mm; pH 7,1±0,08-7,7±0,04; moisture content 35,47-91,97%; elongation 16,33±3,66-53,29±6,13%; and tensile strength 0,0528±0,00-3,9871±0,04 MPa.. Conclusion: Different concentrations of Na-CMC and plasticizer affect the characteristics produced. The best result based on Japanese Industrial Standard (JIS) is formula F5 with 10% Na-CMC concentration and 9% sorbitol as plasticizer
Effects of Enhancment Span-60 of Vernonia amygdalina Leaves Extract-loaded Niosomes Pratiwi, Afrianty; Syahrana, Nur Azizah; Ismail, Isriany; Arsul, Muhammad Ikhlas
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 6 No. 2 (2023)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v6i2.45956

Abstract

Introdiction: Niosomes are a promising drug carrier because of their bilayer structure and the fact that they are produced by the self-association of nonionic surfactants and cholesterol in an aqueous phase. Niosomes are non-toxic, biodegradable, and compatible with human cells. Aims: This research aimed to create niosomes from V. amygdalina leaves and investigate how span 60 addition affects niosome properties. Methods: Extraction V. amygdalina using maceration, niosomes synthesized using a thin-film hydration process, and characterization performed by SEM, particle size, polydispersity index, zeta potential, and FTIR. Conclusion: V. amygdalina succesfully to loaded into niosomes. Span-60 with various concentration affected of characterization of niosomes. Increased span-60 increasing particle size, polydispersity index, and %EE.
Studi Pustaka: Pengaruh Metode Ekstraksi Terhadap Kualitas Gelatin dari Ikan dengan Pretreatment Asam dan Basa Jaya, Adrian; Ismail, Isriany; Arsul, Muhammad Ikhlas
Jurnal Farmasi UIN Alauddin Makassar Vol 12 No 1 (2024): Jurnal Farmasi Edisi Mei
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jfuinam.v12i1.38150

Abstract

Pendahuluan: Gelatin ikan merupakan gelatin alternatif yang bersifat multifungsi yang diperoleh dari hidrolisis kolagen dari bagian ikan meliputi sisik, kulit maupun tulang dengan metode ekstraksi tertentu. Tujuan: Untuk mendapatkan informasi dari berbagai sumber literatur mengenai pengaruh metode ekstraksi gelatin ikan terhadap kualitas gelatin dalam upaya mengembangkan metode yang paling efisien dalam produksi gelatin ikan. Metode: Penulisan artikel ini adalah literature review yaitu sebuah pencarian literatur baik international maupun nasional yang dilakukan dengan menggunakan database pubmed, sciencedirect, dan google schoolar. Penelusuran dan analisis artikel menggunakan metode PICO (Population, Intervention, Comparison, Outcome). Hasil: Terdapt 28 artikel yang memenuhi kriteria untuk selanjutnya dilakukan analisis dengan melihat metode ekstraksi gelatin dan karakteristik gelatin. Kesimpulan: Semakin tinggi suhu ekstraksi, semakin rendah nilai Gel strength dan kadar abu dari gelatin yang dihasilkan. Semakin tinggi suhu ekstrkasi maka semakin tinggi nilai viskositas. Pada hasil analisis diperoleh bahwa pH optimum diperoleh pada ekstraksi gelatin berada pada kisaran 4,5-6,5.
Analisis Perbandingan Angka Bakteri Coliform antara Air Minum Isi Ulang Langsung di Depot dengan Air Minum Isi Ulang yang Beredar di Pasaran Muhammad Rifqi Abdillah; Arsul, Muhammad Ikhlas; Afrisusnawati Rauf; Mukhriani
Jurnal Farmasi UIN Alauddin Makassar Vol 10 No 1 (2022): On Progress
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jfuinam.v10i1.51026

Abstract

Pendahuluan: Depot air minum isi ulang (DAMIU) merupakan tempat pengisian air minum atau industri penyedia air bersih siap minum. Berdasarkan keputusan Menteri perindustrian dan perdagangan DAMIU hanya boleh mengisi wadah yang dibawa konsumen dan tidak boleh melakukan stok air yang sudah dikemas dalam wadah karena beresiko tercemar bakteri, namun saat ini banyak depot yang melakukan stok bahkan mengedarkan air isi ulang ke toko. Tujuan:Penelitian ini bertujuan untuk menganalisa perbedaan angka cemaran bakteri Coliform air minum yang diambil langsung dari depot dan air minum isi ulang yang diedarkan ke toko. Metode: Penentuan cemaran bakteri Coliform dilakukan dengan teknik filtrasi membran. Sampel pada penelitian terdiri dari 2 kelompok yaitu kelompok depot dan kelompok toko yang masing-masing kelompok memiliki 10 sampel. Hasil: Penelitian menunjukkan bahwa seluruh sampel uji mengandung bakteri coliform. Berdasarkan uji statistik terdapat perbedaan yang signifikan antara kedua kelompok sampel uji. Kesimpulan: Hasil yang diperoleh menunjukkan resiko cemaran mikroba tinggi yang tidak memenuhi peryaratan BPOM, sehingga perlu dilakukan pengujian secara berkala dan melakukan standarisasi persyaratn hygiene untuk memperolej kualitas air minum yang berkualitas, bersih, bebas mikroba dan sehat untuk masyarakat.
Parang Romang (Boehmeria virgata (Frost.) Guill.): Correlation of Phytochemistry with Antioxidant and Xanthine Oxidase Inhibitory Activities Arsul, Muhammad Ikhlas; Fidrianny, Irda; Insanu, Muhamad
HAYATI Journal of Biosciences Vol. 31 No. 3 (2024): May 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.3.457-464

Abstract

Secondary metabolites such as phenolic and flavonoid from the plant are essential in their activity, especially activities related to the prevention of oxidation and the inhibition of xanthine oxidase. One plant that is believed to have prevention of oxidation and XOI and correlates with secondary metabolites is parang romang. The purpose of this study is to assess the antioxidant capacity and xanthine oxidase inhibitory activities of parang romang, and to examine their relationship with the TPC and TFC. Total phenolic and flavonoid were measured for all parts, and the DPPH, FRAP, and CUPRAC methods determined antioxidant capacity. The activity of xanthine oxidase inhibition was also assessed. Flavonoids, alkaloids, and coumarin were found in parang romang. The steroid/triterpenoid was found in the stem, leaves, and flower; saponin was in the roots and flower; quinone and tannin were only in the roots. The root gave the highest of TPC, while the flower had the highest TFC. The highest antioxidant capacity was found in roots, leaves, flowers, and stems. The highest xanthine oxidase inhibitory was given by leaves (9.74±0.14 µg/ml), followed by flower, steam, and rood. The correlation was shown between the phenolic and flavonoid quantities and the actions of antioxidants and xanthine oxidase inhibitors.
Co-Authors Abbas, Nurfahima Afrisusnawati Rauf Irda Fidrianny Isriany Ismail Jaya, Adrian Muhamad Insanu Muhammad Rifqi Abdillah Mukhriani Ningsi, Surya Pratiwi, Afrianty Syahrana, Nur Azizah