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Journal : Jurnal Sains dan Kesehatan

Gambaran Kadar Asam Urat Pada Pasien Gagal Ginjal Supriyatin Supriyatin; Misika Alam; Oktafirani Al Sas; Evita Nurjanah
Jurnal Sains dan Kesehatan Vol. 5 No. 2 (2021): Desember : Jurnal Sains dan Kesehatan (JUSIKA)
Publisher : Universitas Muhamadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jusika.v5i2.508

Abstract

Uric acid or urine acid is a product of purine nucleic acid catabolism. Uric acid is produced from within the body (genetic) and from outside (food consumed). Uric acid is measured to assess purine metabolism abnormalities, to confirm the diagnosis and monitoring of treatment, and to detect abnormalities in kidney function. In this situation, the results of purine metabolism (uric acid) that should be excreted out of the body through the kidneys do not occur, so that uric acid in the blood will increase over time. Kidney failure disease kidney organ function has decreased so that eventually unable to work as a filter, dispose of body electrolytes, and maintain fluid and chemical balance in the blood or urine production. This study aims to determine uric acid levels and the percentage of uric acid levels that are outside the normal range and the relationship between hemodialysis time and uric acid levels in patients with kidney failure. The research method used is the descriptive method and the examination method uses the uricase enzymatic method. For data analysis using the SPSS Bivariate test program with Spearmen's Rank test with a sig value of 0.608 which was carried out on 32 samples of serum from hemodialysis patients at random. The results of this study showed that the average uric acid level was 7.1 mg/dL, while normal uric acid levels were 2.7 mg/dL, and the highest was 10.2 mg/dL. Uric acid levels that showed normal results were 12 respondents or 37.5% and increased results were 20 respondents or 62.5%. There is no relationship between the length of hemodialysis time and uric acid levels in patients with kidney failure.
Pengaruh Konsumsi Jus Nanas Terhadap Kadar Asam Urat Pada Wanita Menopause Ikhwani Ikhwani; Supriyatin Supriyatin; Misika Alam
Jurnal Sains dan Kesehatan Vol. 5 No. 1 (2021): Juni : Jurnal Sains dan Kesehatan (JUSIKA)
Publisher : Universitas Muhamadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jusika.v5i1.517

Abstract

Abstract. Gout often attacks people over the age of 30, this is because at that age the declining esterogenous levels can cause uric acid levels in the blood to increase. High uric acid levels can be overcome with a variety of treatments including nonpharmacological treatment in the form of giving pineapple juice. Prevention that can be done to keep uric acid levels normal is by limiting purine foods, choosing low-purine foods, avoiding taking drugs, and taking vitamin C supplements including consuming pineapple juice. The purpose of this study was to determine uric acid levels before and after giving pineapple juice and to determine the difference in results before and after giving pineapple juice on uric acid levels in menopausal women. The research method was pre experiment and the method of examining uric acid levels using the POCT method. The population in the study were 25 menopausal women aged 45-55 years in RW 3 Kaliwadas Village, Cirebon Regency. The sample in the study was 22 menopausal women, with the sampling technique using purposive sampling. Data from the examination of uric acid levels before and after the administration of pineapple juice obtained the results of 21 samples that experienced a decrease (95.45%) and 1 sample that experienced an increase (4.45%) with an average uric acid level before 5.6 mg/dL with the highest level of 8.4 mg/dL and the lowest level of 4.7 mg/dL and the average after 5.3 mg/dL with the highest level of 8.4 mg/dL and the lowest level of 3.7 mg/dL. The research data were analyzed using a normality test and paired sample T-test obtained Sig. (2-tailed) 0.000 <0.005. based on this study it can be concluded that there is an influence on uric acid levels before and after being given pineapple juice.