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All Journal Dentino: Jurnal Kedokteran Gigi Mulawarman Dental Journal
Muthi’ah, Nisa
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Immunology & microbiology Public Health

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EXPRESSION OF CALRETININ IN AMELOBLASTOMA AND ODONTOGENIC CYST IN A.W. SJAHRANIE GENERAL HOSPITAL SAMARINDA Pramasari, Cristiani Nadya; Irawiraman, Hadi; Sawitri, Endang; Muthi’ah, Nisa; Sulistiani, Dewi Arsih; Prinadira, Sarah
Dentino: Jurnal Kedokteran Gigi Vol 9, No 1 (2024)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v9i1.18871

Abstract

Background : Ameloblastoma and odontogenic cysts have similar clinical and radiographic features but different treatments. Diagnosis is established by histologic features, but sometimes this step have difficulty making appropriate assessment because epithelial cells can show various variations. Preoperative misdiagnosis may result in inefficient treatment. In such situations, immunohistochemistry (IHC) with the use of proper markers might be needed for the differentiation of these lesions. Purpose : This study aimed to assess calretinin expression in ameloblastoma and various odontogenic cysts so that calretinin can be used as a specific diagnostic marker for ameloblastoma. Method : This was a retrospective analytical study of immunohistochemical examination of calretinin expression in ameloblastoma and odontogenic cysts. A total of eighty cases, in which thirty four cases of ameloblastoma and forty six cases of odontogenic cysts were included in the study. Slides were made from the paraffin blocks of each case and were stained immunohistochemically with calretinin. Results : In ameloblastoma, almost all subjects expressed calretinin, i.e. 33 (97.1%), followed by radicular cyst 7 (46.7%), odontogenic cyst 2 (40.0%), then dentigerous cyst 6 (26.1%) and OKC 0 (0.0%). The results of the analysis of the Chi-Square test showed a significant difference with a p-value < 0.001. Conclusion : The study concluded that calretinin was mainly expressed in ameloblastoma, whereas majority of  odontogenic cyst groups showed negative for calretinin in various percentages. Calretinin may be a specific immunohistochemical marker for ameloblastoma. Keywords : Ameloblastoma, Calretinin, Immunohistochemical, Odontogenic cyst, Odontogenic tumor
Gambaran Perilaku Kontrol Plak Sebagai Upaya Pencegahan Penyakit Periodontal Pada Remaja Akhir di Kecamatan Sangkulirang Kabupaten Kutai Timur Khairi, Nur Hijria Miftahul; Muthi’ah, Nisa; Utami, Nuryanni Dihin
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Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/mul. dent. j.v4i2.10705

Abstract

Latar Belakang: Perilaku kontrol plak merupakan bentuk upaya pencegahan terjadinya penyakit periodontal. Perilaku mencakup pengetahuan, sikap, dan tindakan. Kontrol plak dilakukan secara mekanis dengan menyikat gigi dan membersihkan daerah interdental serta secara kimiawi dengan penggunaan obat kumur dan penggunaan fluoride pada pasta gigi. Tujuan: Tujuan penelitian ini untuk mengetahui gambaran perilaku kontrol plak sebagai upaya pencegahan penyakit periodontal pada kelompok usia remaja akhir di Kecamatan Sangkulirang Kabupaten Kutai Timur. Metode: Penelitian ini dilakukan dengan pendekatan cross sectional Hasil: Hasil penelitian menunjukkan sebanyak 68,75% responden memiliki pengetahuan kontrol plak dengan kategori sedang, 60,42% responden memiliki sikap kontrol plak dengan kategori sedang, dan 48,96% responden melakukan tindakan kontrol plak dengan kategori sedang.  Kesimpulan: Perilaku kontrol plak pada remaja akhir di Kecamatan Sangkulirang Kabupaten Kutai Timur berada dalam kategori sedang. Edukasi dan pelatihan diperlukan untuk meningkatkan perilaku kontrol plak pada masyarakat khususnya remaja akhir di Kecamatan Sangkulirang Kabupaten Kutai Timur.
Co-Authors Endang Sawitri Irawiraman, Hadi Khairi, Nur Hijria Miftahul Nuryanni Dihin Utami, Nuryanni Dihin Pramasari, Cristiani Nadya Prinadira, Sarah Sulistiani, Dewi Arsih