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Astindari
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Immunology & microbiology Public Health

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Antifungal Activity of Rosemary (Rosmarinus officinalis L.) Emulsion Gel Compared to Nystatin on Candida albicans Stored Isolate from HIV/AIDS Patients with Oral Candidiasis Wardiana, Maya; Astindari; Ervianti, Evy; Afif Nurul Hidayati; Diah Mira Indramaya; Pepy Dwi Endraswari; Budi Utomo; Dwi Murtiastutik
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 2 (2023): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.2.2023.88-92

Abstract

Background: Oral candidiasis (OC), frequently caused by Candida albicans, is the most common opportunistic infection in HIV/AIDS patients. Topical treatment for OC is limited. In vitro study revealed rosemary (Rosmarinus officinalis L.) essential oil has an antifungal effect. However, the essential oil is volatile and is not recommended to be applied to the skin and mucosa; therefore, emulsion gel (emulgel) is made. Purpose: This study was conducted to evaluate the antifungal activity of rosemary emulgel 6.25%, 25%, 37.5%, and 50% compared to nystatin. Methods: This study is an in vitro test using the disk diffusion method to d  etermine the antifungal activity shown by the inhibitory zones of rosemary emulgel at 6.25%, 25%, 37.5%, and 50% compared to nystatin to stored isolates of C. albicans from HIV/AIDS patients with OC. Result: Rosemary emulgel 6.25% dan 25% did not show antifungal activity because no inhibitory zone was shown. The inhibitory zone diameter provided by rosemary emulgel 37.5%; 50%; and nystatin against C. albicans isolates were 3.17±3.763 mm; 7.00±4.107 mm; and 30.13±5.319 mm respectively. Significant differences in antifungal activity were shown by the inhibitory zone diameter provided between rosemary emulgel 37.5%, 50%, and nystatin (p<0,05). Conclusion: Rosemary emulgel 37.5% dan 50% had antifungal activity showed by the formation of inhibitory zone against Candida species isolates in disk diffusion method even though it was weaker compared to nystatin as a standard antifungal.
Occupational Contact Dermatitis Risk Factors on Healthcare Workers Isolation Ward During the COVID-19 Pandemic Yuindartanto, Andre; Sawitri; Astindari; Damayanti; Anggraen, Sylvia; Umborowati, Menul Ayu; Zulkarnain, Iskandar; Listiawan, M. Yulianto; Hidayati, Afif Nurul; Cita Rosita Sigit Prakoeswa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 1 (2023): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.1.2023.27-39

Abstract

Background: After a history of exposure to the suspected material and a thorough physical examination, the diagnosis of occupational contact dermatitis (OCD) is commonly suspected. During the initial consultation, essential information involving the above is frequently neglected. Purpose: To evaluate the clinical manifestations of OCD cases in health workers and analyze the factors that influence OCD cases in health workers at the isolation ward of Dr. Soetomo Surabaya Hospital during the COVID-19 pandemic. Methods: The sample selection was done through purposive sampling. Accessible population that met the inclusion criteria and did not have exclusion criteria were included as research samples. The target population was healthcare workers in the Special Isolation Ward of Dr. Soetomo Hospital Surabaya. The accessible population was healthcare workers who performed hand hygiene activities and used Personal Protective Equipment (PPE) in the Special Isolation Ward of Dr. Soetomo Hospital Surabaya. The research subjects were healthcare workers who worked in the Special Isolation Ward. Result: The research results showed a strong and significant correlation between atopic history and the occurrence of contact dermatitis due to poor skin barrier function and decreased tolerance. The study also found that there was no significant correlation between atopic history and the severity level of OCD. There was a significant difference in transepidermal water loss (TEWL) values in the lesion and non-lesion areas, both on the palmar and dorsal aspects of the hand. Moisturizer is an important component in managing hand dermatitis as it can repair and maintain the skin's protective barrier. Conclusion:
Knowledge Improvement of Xerosis Cutis through Health Education in the Elderly Damayanti; Astindari; Indranarum, Trisiswati; Hadiwidjaja, Farsha Naufal; Axelia, Presstisa Gifta; Hasnikmah Mappamasing
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.174-177

Abstract

Background: Xerosis cutis presents in more than 50% of the elderly population and is currently the most common complaint related to a skin condition in the elderly population. However, many of them are still uninformed of this complaint. Education plays an important role in the management of xerosis cutis, such as how to identify and avoid triggering factors and how to break the itch-scratch cycle. Purpose: This study aims to evaluate the level of knowledge on xerosis cutis in the elderly population after receiving health education. Methods: This observational study involved 71 subjects who met the inclusion criteria of being elderly and were willing to participate in this study. The data were collected using questionnaires. The level of knowledge was assessed before and after the health education around xerosis cutis. Result: Eleven (15.49%) male and 60 (84.51%) female subjects participated in this study. There was a significant difference mean scores between the pre-test and post-test after health education (p= <0.001). The means of total scores of the pre-test and post-test were 11.72 ± 1.475 and 12.58 ± 1.662. The questionnaire consisted of  chapters regarding skin changes in the elderly, risk factors for xerosis cutis, and management of xerosis cutis. A significant difference in score between the pre-test and post-test was found in all the chapters (p=0.046, p=0.002, and p=0.006). Conclusion: Following health education, there was an improvement in the elderly's level of knowledge on xerosis cutis.
Co-Authors Afif Nurul Hidayati Afif Nurul Hidayati, Afif Nurul Anggraen, Sylvia Axelia, Presstisa Gifta BUDI UTOMO Cita Rosita Sigit Prakoeswa Damayanti Diah Mira Indramaya Dwi Murtiastutik Evy Ervianti Hadiwidjaja, Farsha Naufal Hasnikmah Mappamasing Indranarum, Trisiswati M. Yulianto Listiawan Menul Ayu Umborowati, Menul Ayu Pepy Dwi Endraswari, Pepy Dwi Sawitri T. Riza Zarzani N Wardiana, Maya Yuindartanto, Andre