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All Journal Health Science Journal of Indonesia Mutiara Medika: Jurnal Kedokteran dan Kesehatan Jurnal Sains Psikologi Raheema Molecular and Cellular Biomedical Sciences (MCBS) Al-Hikmah INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Cermin Dunia Kedokteran Indonesian Journal of Cancer

Sari Eka Pratiwi

Departemen Biologi Dan Patologi, Fakultas Kedokteran, Universitas Tanjungpura, Pontianak, Kalimantan Barat, Indonesia

Author-ID : 773558

Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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RISIKO PERILAKU SEKSUAL TIDAK AMAN PADA POPULASI LGBT TERHADAP INFEKSI VIRUS YANG MENULAR SECARA SEKSUAL Sari Eka Pratiwi; Fitri Sukmawati
Raheema Vol 6, No 1 (2019): Perempuan dan Politik
Publisher : PSGA LP2M IAIN Pontianak

Approximately 10% global population are homosexual (lesbian, gay), bisexual and transgender community (LGBT), who have a tendency to get several health problems, including sexually transmitted infections. This risk increase in line with the propensity of alcohol consumption, drugs and sexual abuse, which are found commonly in lesbian, gay and bisexual communities. This study’saim is to correlate the sexual behavior-related risk among LGBT community to the health problems such as sexually transmitted infections. This study was started with collecting the references and research publications, studied the LGBT community and the diseases related to the risky behavior of these population. LGBT population are at high risk to receive several health problems including Hepatitis B virus infection (HBV), Hepatitis C virus infection (HCV) and Human Immunodeficiency Virus(HIV). The increment of the risks are caused by unsave sexual behaviour such as having more than one sexual partner, unprotected sexual intercourse via anal and vagina, drugs and alcohol consumption, which are commonly discovered in LGBT population. Keywords: Bisexual, Community, problem Hampir sekitar 10% populasi dunia termasuk dalam populasi penyuka sesama jenis (lesbian, gay), biseksual dan transgender (LGBT) yang memiliki kecenderungan mendapatkan berbagai masalah kesehatan salah satunya infeksi menular seksual. Risiko ini meningkat sejalan dengan kecenderungan konsumsi alkohol, ganja dan kekerasan seksual yang umum ditemukan pada lesbian, gay dan biseksual.Telaah artikel ini bertujuan untuk menghubungkan resiko terkait perilaku seksual pada LGBT terhadap gangguan kesehatan yaitu infeksi menular seksual.Telaah artikel dilakukan dengan menelusuri berbagai literatur ilmiah mengenai kelompok LGBTdan gangguan kesehatan yang berkaitan dengan perilaku beresiko yang dilakukan oleh kelompok ini.Populasi penyuka sesama jenis (lesbian, gay), biseksual atau transgender (LGBT) merupakan kelompok yang berisiko tinggi mengalami berbagai masalah kesehatan, termasuk infeksi virus Hepatitis B (HBV), Hepatitis C (HCV) dan Human Immunodeficiency Virus (HIV). Risiko ini meningkat akibat perilaku seksual yang tidak aman seperti memiliki lebih dari satu pasangan seksual, hubungan seksual melalui anal maupun vagina yang tidak menggunakan pelindung, penggunaan obat-obatan dan alkohol, yang umum ditemukan pada populasi LGBT. Keywords: LGBT, Menular, Seksual

VITAMIN D AND SEROTONIN’S ROLE IN NEUROPSYCHIATRIC DISORDERS SARI EKA PRATIWI; FITRI SUKMAWATI
Raheema Vol 7, No 1 (2020)
Publisher : PSGA LP2M IAIN Pontianak

Abstract Vitamin D is known to play an active role in the development of nerve cells, as well as regulating the expression of one of the important genes in serotonin metabolism, namely THP2. Vitamin D and serotonin play an important role in the development of various neuropsychiatric diseases, Autism spectrum disorder (ASD), schizophrenia, bipolar disorder, and depression. Method: An article review was carried out by tracing various scientific literature relating to theories regarding the relationship of vitamin D and Serotonin, as well as neuropsychiatric disorders related to metabolic disorders and the production of vitamin D and serotonin. Results: The biological activity of vitamin D is mediated by the vitamin D receptor (VDR). The bonding complex between VDR and VDRE in the promoter of a gene will initiate the transcription process, one of which is TPH2, which plays an active role in the synthesis of brain serotonin. Serotonin has an important role as a neurotransmitter, hormone and morphogen for the brain. This neurotransmitter have important functions in the brain in controlling appetite, energy expenditure, sleep, body temperature, mood, and social cognition. Conclusion: Vitamin D plays an active role in the transcription of TPH2, which plays an active role in the synthesis of brain serotonin. Vitamin D facilitate tryptophan metabolism by increasing TPH2 to synthesize serotonin. Disruption of vitamin D levels will change serotonin levels and function in the brain, resulting in impaired behavior and executive brain function. Keyword: Vitamin D, Serotonin, Autism, Autism Spectrum Disorder

MiR-141-3p Relative Expression Level from FFPE Samples as Biomarker of Prostate Adenocarcinoma Carcinogenesis in Yogyakarta, Indonesia Sari Eka Pratiwi; Sri Nuryani Wahyuningrum; Rachmagreta Perdana Putri; Danarto Danarto; Didik Setyo Heriyanto; Nur Arfian; Sofia Mubarika Haryana; Indwiani Astuti
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 4 No 1 (2022): The future of diagnostic laboratory testing
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v4i1.2355

Globally, prostate cancer (PCA) is the second leading cause of male cancer-associated mortality. Micro-RNAs (miRNAs) are small non-coding RNAs considered promising biomarkers for diagnosis, prognosis, and treatment options. A miR-141 expression is frequently dysregulated and influences the development and progression of PCA. This study aimed to identify miR-141 expression level as a marker to differentiate PCA from another prostate anomaly, especially in Yogyakarta. Formalin-fixed paraffin-embedded (FFPE) tissues for each three groups: benign prostatic hyperplasia/BPH, high-grade prostatic intraepithelial neoplasia/HGPIN, and PCA (n=7/group) were stored in a commercial clinical laboratory in Yogyakarta. The total RNA was extracted from FFPE sections using miRNeasy FFPE kit, followed by the quantification of miR-141-3p expression level by RT-PCR. The result showed that miR-141 relative expression level on PCA was higher than other groups and significantly different (P<0.05, Kruskal Wallis test). The mean of the miR-141 relative expression level of BPH, HGPIN, and PCA were 1.04±0.87, 6.44±7.8, and 7.06±8.83, respectively. The relative expression level of miR-141 can potentially be a prognostic biomarker in PCA and could differentiate aggressiveness in prostate anomaly, especially BPH, HGPIN, and PCA.

Overexpression of MiR-155-5p and increased number of macrophage population in precancerous prostatic disease Rachma Greta Putri; Sari Eka Pratiwi; Didik Setyo Heriyanto; Danarto Danarto; Indwiani Astuti; Nur Arfian; Sofia Mubarika Haryana
Health Science Journal of Indonesia Vol 11 No 2 (2020)
Publisher : Sekretariat Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/hsji.v11i2.3952

Latar Belakang: Gangguan regulasi mikroRNA(miR) dan inflamasi kronik dapat mengubah tumor menjadi karsinoma dan kanker dengan metastasis melalui perubahan seluler dan genomik. Lesi prekanker memiliki peluang 33,3 persen menjadi kanker. Penelitian ini bertujuan untuk mengkaji peran miR-155-5p terhadap mRNA SOCS1 dan populasi makrofag terhadap progresivitas penyakit yang berhubungan dengan Benign Prostate Hyperplasia (BPH), High Grade Prostatic Intraepithelial Neoplasia (HGPIN), dan Prostate Adenocarcinoma (PRAD). Metode: Penelitian ini merupakan penelitian potong lintang dengan 3 kelompok, yaitu BPH,HGPIN, dan PRAD. Sampel jaringan didapatkan dari Tindakan TURP. Ekspresi miR-155 dianalisis menggunakan qPCR dan dikalkulasi menggunakan metode Livak. Ekspresi mRNA SOCS-1 dianalisis menggunakan reverse transcriptase PCR. Penanda pan makrofag, anti CD-68 monoclonal antibody(MoAb) digunakan untuk mendeteksi populasi makrofag pada jaringan dengan imunohistokimia. Hasil: Ekspresi miR-155 lebih tinggi pada HGPIN dibandingkan BPH dan PRAD (p=0,14). Ekspresi mRNA SOCS1 pada HGPIN paling rendah diantara ketiga sampel (p=0,96). Terdapat korelasi negative antara miR-155 dan mRNA SOCS1 (p=0,02). Terdapat peningkatan persentase populasi makrofag yang signifikan pada HGPIN (6,03 persen) dibandingkan BPH (0.89 persen) dengan p=0,00. Kesimpulan: Pada penelitian ini, terdapat perubahan persentase makrofag dan miR-155 pada HGPIN. Variasi ekspresi miR-155 dan persentase populasi makrofag dapat disebabkan karena perubahan epigenetik. Oleh sebab itu, perlu penelitian lebih lanjut untuk memvalidasi hasil tersebut dan memahami kemungkinan menjadi biomarker pada penyakit prekanker pada prostat. Kata Kunci: Prostatic Intaepithelial Neoplasia, miR-155, Makrofag Abstract Background: Impaired microRNA(miR) regulation and chronic inflammation could transform tumors into carcinoma and cancer by metastasis through cellular and genomic changes. Precancerous lesions have a 33.3 percent chance of becoming cancerous. This study investigated the role of miR-155 related to SOCS1 mRNA and macrophage population in disease progression associated with Benign Prostate Hyperplasia (BPH), High-Grade Prostatic Intraepithelial Neoplasia (HGPIN), and Prostate Adenocarcinoma (PRAD). Methods: This was a cross-sectional study using three groups of samples, namely BPH, HGPIN, and PRAD. Tissue samples were obtained from TURP Action. The expression of miR-155 was analyzed using real-time qPCR and calculated using the Livak method. The expression of SOCS1 mRNA was analyzed using reverse transcriptase PCR. The macrophage pan-marker, anti-CD68 monoclonal antibody (MoAb), was used to detect macrophage population in tissues by immunohistochemistry. Results: The expression of miR-155 was higher in HGPIN than BPH and PRAD (p=0.14). The expression of SOCS1 mRNA in HGPIN was the lowest among the three samples (p=0.96). There was a negative correlation between miR-155 and SOCS1 mRNA (p=0.02). There was a significant increase in the percentage of the macrophage population in HGPIN (6.03 percent) compared to BPH (0.89 percent) with p=0.00. Conclusion: In this study, there were changes in the percentage of macrophage and miR-155 in HGPIN. The variation in miR-155 expression and the percentage of the macrophage may be caused by epigenetic changes. Therefore, further research is needed to validate these results and understand the possibility of being a biomarker in precancerous disease of the prostate. Keywords: Prostatic Intraepithelial Neoplasia, miR-155, Macrophage

ZEB1 is Negatively Correlated with E-Cadherin in Prostatic Anomaly Tissue Sari Eka Pratiwi; Sri Nuryani Wahyuningrum; Rachmagreta Perdana Putri; Danarto Danarto; Didik Setyo Heriyanto; Nur Arfian; Sofia Mubarika Haryana; Indwiani Astuti
Molecular and Cellular Biomedical Sciences Vol 6, No 1 (2022)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v6i1.220

Background: Prostatic anomalies are common in tumor or infection condition. The enlargement of prostate gland affects the epithelial cell polarity that involves epithelial-mesenchymal transition (EMT). Transition into mesenchymal is mediated by transcription factor ZEB1 and E-cadherin protein. Upregulation of ZEB1 and loss of E-Cadherin expression were associated to proliferation and metastasis of malignancy cells. This study aims to describe the correlation of ZEB1 and E-cadherin expression in prostatic anomaly.Materials and method: Samples were Formalin Fixed Paraffin Embedded (FFPE) block consist of 8 block Benign Prostatic Hyperplasia (BPH), 6 blocks High Grade Prostatic Intraepithelial Neoplasia (HGPIN) and 6 blocks Prostate Carcinoma (PCA). The blocks then sliced into 5 sections to be prepared for RNA extraction procedures. ZEB1 and E-Cadherin expression was analyzed by semi-quantitative procedures using PCR and electrophoresis. Correlation between ZEB1 and E-Cadherin espression was analyzed using Spearman’s rank correlation.Results: Relative expression of ZEB1 and E-cadherin mRNA in each group of prostatic anomaly were not significantly different (p>0.05). ZEB1 and E-Cadherin mRNA expression showed a significant and moderate level of negative correlation (p<0.05; 0.40 < r < 0.59). Increasing of ZEB1 mRNA expression will be followed by decreasing of E-Cadherin mRNA expression.Conclusion: ZEB1 negatively correlates with E-cadherin due to EMT process in prostatic anomaly. High expression of ZEB1 induced down-regulation of E-cadherin and vise versa. Various studies can be developed, especially the development of targeted therapy against ZEB1 to suppress the EMT process by increasing the expression of E-cadherin.Keywords: epithelial-mesenchymal transition (EMT), ZEB1, E-Cadherin, BPH, HGPIN, PCA

Disorientasi Seksual dari Perspektif Psikologi dan Agama Islam : Lesbian, Gay, Biseksual dan Transgender Fitri Sukmawati; Sari Eka Pratiwi
Jurnal Al-Hikmah: Jurnal Dakwah Vol 14, No 1 (2020)
Publisher : INSTITUT AGAMA ISLAM NEGERI PONTIANAK

Homosexual is a sexual behavior with same-sex attraction or interest. Meanwhile, other group is biseksual, a sexual orientation towards both genders. The last LGBT group is transgender or transsexual, a group of people with sex-identity problems. This study aims to analize the factors which are influenced the formation of sexual disorientation, LGBT. The study started with literatures searching related with the teories of sexual disorientation in psychology and Islamic aspects. LGBT is not only a behavior that naturally occur, but it is formed by socio-cultural process in the early phase of human creation. There are three main factors which are basically form the LGBT behavior, including biologic, psychologic and sosio-cultural factors. Abstrak Homoseksual adalah perilaku seks dengan ketertarikan pada sesama jenis kelamin.Sementara itu kelompok lainnya yaitu biseksual adalah penyaluran dan orientasi seks pada dua jenis kelamin. Kelompok yang merupakan bagian dari LGBT yang terakhir adalah transgender atau transeksual, yaitu sekelompok orangdengan masalah identitas gender. Telaah literatur ini ditulis dengan tujuan untuk menelaah faktor-faktor yang mempengaruhi terbentuknya disorientasi seksual yaitu LGBT.Telaah artikel dilakukan dengan menelusuri berbagai literatur ilmiah yang berkaitan dengan teori-teori mengenai disorientasi seksual dari sudut pandang psikologi dan agama Islam. Perilaku LGBT bukan hanya sesuatu yang bersifat alami atau dibentuk oleh suatu proses sosial budaya pada awal penciptaan manusia. Terdapat tiga faktor utama yang melatarbelakangi terbentuknya perilaku LGBT, yaitu faktor biologis, psikologis dan sosial budaya.

PENGARUH POLA ASUH ORANG TUA DAN DIET BEBAS GLUTEN/KASEIN TERHADAP PERBAIKAN GEJALA AUTISM SPECTRUM DISORDER (ASD) Sari Eka Pratiwi; Fitri Sukmawati
Jurnal Al-Hikmah: Jurnal Dakwah Vol 13, No 1 (2019)
Publisher : INSTITUT AGAMA ISLAM NEGERI PONTIANAK

Autism Spectrum Disorder (ASD) is a development impairment characterized by cognitive and neurobehavioral deficit, including communication and social problem that need psycology and education intervention for the children and the parents, also nutrition intervention with Gluten-Free Casein-Free (GFCF). This study’s aim is to identify the parenting style and Gluten-Free Casein-Free diet role in ASD’s symptoms modification. This study was start with collecting the references and research publications, and study the relationship of parenting style and GFCF diet to ASD. Flexible Parenting style in ASD is important and need to be adjusted based on the characteristic, development stage and the children’s situation. Diet GFCF can be a complementary therapy to reduce ASD’s symptoms particularly children with gluten allergy and have celiac disease. However, the children without any gastrointestinal symptoms to gluten/casein products need a consideration and advance examination to determine GFCF diet requirement. [Autism Spectrum Disorder (ASD) merupakan suatu kelainan perkembangan saraf yang dicirikan dengan adanya defisit kognitif dan neurobehavioralyang mencakup masalah komunikasi dan perilaku sosial, yang memerlukanintervensi psikologis dan edukasi pada anak dan orang tua, serta intervensi nutrisi dengan pembatasan asupan gluten dan kasein yang dikenal dengan diet Gluten-Free Casein-Free (GFCF). Penulisan telaah jurnal ini bertujuan untuk mengetahui pengaruh pola asuh orang tua dan pembatasan asupan gluten dan kasein terhadap perbaikan gejala ASD. Penulisan telaah literatur dilakukan dengan mengumpulkan berbagai sumber teori dan hasil penelitian kemudian dilakukan telaah terhadap hubungan kedua faktor yaitu pola asuh dan pembatasan asupan gluten dan kasein terhadap ASD. Gaya pengasuhan pada ASD perlu dilakukan secara fleksibel sesuai dengan keunikan karakter anak, tahap perkembangan anak, dan situasi yang sedang dihadapi. Terapi pembatasan asupan gluten/kasein dapat menjadi pilihan terapi pelengkap untuk mengurangi gejala ASD terutama pada anak yang alergi gluten dan mengalami penyakit celiac. Namun, pada anak yang tidak memiliki gejala saluran cerna terhadap produk gluten/kasein perlu pertimbangan dan pemeriksaan lebih lanjut untuk menentukan perlu tidaknya pembatasan gluten/kasein pada makanannya]. Kata Kunci: Autism Spectrum Disorder (ASD), Gluten-Free Casein-Free (GFCF), Pola Asuh Pada ASD, Autisme, Terapi Nutrisi Autism Spectrum Disorder (ASD).

Efek Ekstrak Etanol Daun Kesum (Polygonum minus Huds.) terhadap Jumlah Netrofil, Monosit dan Limfosit Tikus Putih Jantan Galur Wistar yang Diinduksi Karagenin Hizki Ervando; Erni -; Muhammad Afzalurrahman Putranda; Joni T. Parinding; Sari Eka Pratiwi
Cermin Dunia Kedokteran Vol 46, No 6 (2019): Diabetes Mellitus
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i6.465

Latar belakang: Tanaman Kesum (Polygonum minus Huds.) merupakan tanaman endemik daerah Kalimantan Barat mengandung flavonoid yang dipercaya dapat berperan sebagai antiinflamasi. Tujuan: Mengetahui efek ekstrak etanol daun Kesum terhadap jumlah netrofil, monosit dan limfosit tikus putih jantan galur Wistar yang diinduksi karagenin. Metode: Desain penelitian true experimental dengan complete randomized design menggunakan 30 tikus yang dibagi menjadi 5 kelompok. Kelompok kontrol negatif diberi CMC 0,5 mg/kgbb.; kontrol positif natrium diklofenak 2,7 mg/kgbb.; perlakuan 1 ekstrak etanol daun Kesum 4,332 mg/200gbb., perlakuan 2 ekstrak etanol daun Kesum 8,664 mg/200gbb. dan perlakuan 3 ekstrak etanol 17,328 mg/200gbb. Karagenin 1% diinduksi pada daerah subplantar. Pengambilan darah, pewarnaan dan hitung jenis leukosit pada jam 0, 4, 8 dan 12 untuk netrofil dan monosit, pada jam 0, 12, 24 dan 48 untuk limfosit. Analisis data menggunakan IBM SPSS v20.0 dengan uji General Linear Model dilanjutkan Post Hoc Bonferroni. Hasil: Pada perlakuan 3 terdapat perbedaan bermakna jumlah netrofil (p<0,05) pada jam ke-4 pada perhitungan apus darah tepi. Simpulan: Ekstrak etanol daun Kesum (Polygonum minus Huds.) memiliki efek terhadap jumlah netrofil.Background: Kesum plant (Polygonum minus Huds.) is West Borneo endemic plant that contains flavonoid believed to have anti-inflammatory activities. Objective: To investigate the effects of ethanol extract of Kesum leaves on white Wistar rat neutrophils, monocytes and lymphocytes count induced by carrageenan. Method: True experiment with complete randomized design on 30 rats divided into 5 groups. Negative control group is given CMC 0,5%; positive control is given 2,7 mg/200 mg BW diclofenac sodium; treatment-1 4,322 mg/200 mg BW; treatment-2 8,644 mg/200 mg BW and treatment-3 17,328 mg/200 mg BW. Carrageenan 1% was induced on sub-plantar area. Blood count and differential leucocytes count were done at 0, 4, 8 and 12 for neutrophils and monocytes, 0, 12, 24 and 48 hours for lymphocytes. Data were analysed using IBM SPSS version 20.0 with General Linear Model test followed by Post Hoc Bonferroni. Results: In treatment-3 there is a significant difference (p<0,05) of neutrophyl count in fourth hour. Ethanol extracts of Kesum leaves have an effect on neutrophyl count.

Knowledge, Attitude, and Behavior of Tanjungpura University Undergraduate Students towards Nasopharyngeal Carcinoma Imelda Dana Bella Ayu Fernanda; Sari Eka Pratiwi; Delima Fajar Liana
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 22, No 2 (2022): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v22i2.14470

Nasopharyngeal carcinoma is the most frequent head and neck cancer. The incidence of nasopharyngeal carcinoma significantly increased. Nasopharyngeal carcinoma is associated with risk factors linked to a lifestyle that usually begins in adolescence and young adulthood, such as undergraduate students. This research identifies undergraduate students' knowledge, attitude, and behavior about nasopharyngeal carcinoma. The study used a descriptive study with a cluster sampling method. As many as 100 undergraduate students from 8 faculties in Tanjungpura University filled out a questionnaire and analyzed using a statistical program with a descriptive statistical test. As much as 82% of respondents had received information about nasopharyngeal carcinoma from various sources. Knowledge was divided into 3 categories of levels, namely good (76-100% correct), fair (56-75% correct), and poor (56%). At the same time, attitude and behavior were divided into positive (score20) and negative (score20). The test results showed that the level of knowledge of the undergraduate students of 52% was good, the attitude was 100% positive, and the behavior was 100% positive. Therefore, undergraduate students at Tanjungpura University had good knowledge, a positive attitude, and positive behavior toward nasopharyngeal carcinoma. This study implies that adequate information is important in determining knowledge, attitudes, and behavior towards nasopharyngeal carcinoma.

The Profile of Cervical Cancer Patients at Soedarso Hospital Sari Eka Pratiwi; Heru Fajar Trianto; Nabilah Nurul Fatinah; Muhammad In’am Ilmiawan; Iit Fitrianingrum; Desriani Lestari
Indonesian Journal of Cancer Vol 16, No 1 (2022): March
Publisher : National Cancer Center - Dharmais Cancer Hospital

Background: The prevalence and mortality rates of cervical cancer differ by region with the highest rates found in Latin America, Southeast Asia, and Africa. In Indonesia, cervical cancer is the second-largest contributor to the latest cases in 2020. In West Kalimantan, over 20,000 women were diagnosed with cervical cancer in 2014. This study aims to describe the characteristics of cervical cancer patients in West Kalimantan. Methods: A descriptive observational study was conducted on patients from 2017 to 2019 according to the Soedarso Hospital database. All medical records were reviewed and analyzed to obtain the variable data; they were age, ethnics, origin, stage of cervical cancer, histopathology types, and hemoglobin (Hb) level. Results: Cervical cancer patients for the 2017–2019 period totaled 147 people with 30 deaths. In this study, 97 patients from 2017 to 2019 met the inclusion criteria. Cervical cancer was found from the age of 27 years with a peak at the age of 41–60 years. Most patients came from Pontianak and Kubu Raya cities (45.4% and 14.4%, respectively) with the most ethnic groups being Malays (41.2%). A total of 43.3% of patients had a parity amount of more than five times. Most patients came at stage IIIb (45.4%). The patients present with moderate to severe anemia with the lowest Hb level of around 2.3 g/dL. Based on histopathology, the type of squamous cell carcinoma ranks the highest (70.1%). Conclusions: Cervical cancer incidence reaches the peak at adults to elderly. The amount of parity seems to contribute to the incidence of cervical cancer in West Kalimantan. Most patients came at an advanced stage and the type of squamous cell carcinoma with moderate to severe anemia

Co-Authors Danarto Danarto Danarto Danarto Danarto Danarto Delima Fajar Liana Desriani Lestari Didik Setyo Heriyanto Didik Setyo Heriyanto Erni Erni - FITRI SUKMAWATI Fitri Sukmawati Glorie Hosiana Maria Simangunsong Handoko, Willy Heru Fajar Trianto Heru Fajar Trianto Hizki Ervando Hizki Ervando Iit Fitrianingrum Iit Fitrianingrum Imelda Dana Bella Ayu Fernanda Indwiani Astuti Indwiani Astuti Indwiani Astuti Joni T. Parinding Muhammad Afzalurrahman Putranda Muhammad Afzalurrahman Putranda Muhammad In’am Ilmiawan Nabilah Nurul Fatinah Nabilah Nurul Fatinah Nur Arfian Nur Arfian Nur Arfian Rachma Greta Perdana Putri Rachma Greta Putri Rahmatania, Ridha Sari Rahmayanti Sofia Mubarika H Sofia Mubarika Haryana Sofia Mubarika Haryana Sri Nuryani Wahyuningrum Sri Nuryani Wahyuningrum Tri Wahyudi

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