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All Journal Indonesian Journal of Medicine Journal of Maternal and Child Health JURNAL ILMU KEFARMASIAN INDONESIA Jurnal Pengabdian Pada Masyarakat METHABDI Majalah Ilmiah METHODA

Endy Juli Anto

Universitas Methodist Indonesia

Author-ID : 874277

Religion Agriculture, Biological Sciences & Forestry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Physics Public Health

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Does HBA1C Correlate with Lipid Profile in Type 2 Diabetes Mellitus? A New Evidence from Medan, North Sumatera Julianto, Endy; Silitonga, Hendrika Andriana; Siahaan, Jekson Martiar
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.036 KB)

Background: Diabetes mellitus (type 2 DM) is now ranked first in health problems and its prevalence tends to increase worldwide. The Diabetes Control and Complication Trial (DCCT) study showed that lowering HbA1c rates may delay or prevent chronic complications. One of the risk factors for CHD in type 2 DM is dyslipidemia, i.e lipid metabolism disorders in the form of elevated total cholesterol, triglyceride (TG), low-density lipoprotein (LDL), and decreased levels of high-density lipoprotein (HDL). This study aimed to determine the correlation between HBA1C and blood sugar, as well as the lipid profile in patients with type 2 DM.Subject and Methods: This was an analytic observational study with a cross-sectional design. The study was conducted at the Endocrinology and Metabolic polyclinic Pirngadi Hospital, Medan, North Sumatera, from January to February 2018. A total sample of 10 patients diagnosed with type 2 diabetes mellitus with obesity was selected for this study. The independent variables were blood sugar, lipid profile including total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglyceride. The dependent variable was the HbA1c level. Lipid profile was measured by blood serum examination. HbA1c level was measured by blood serum examination. The data were analyzed by Pearson correlation.Results: Hba1c was positively correlated with blood sugar levels and was statistically significant (r= 0.81; p= 0.005). HbA1c correlated weakly and was statistically non-significant with total cholesterol (r= 0.14, p= 0.702), LDL (r= 0.15; p= 0.683), HDL (r= 0.04; p= 0.922), and triglycerides (r= 0.06; p= 0.860).Conclusion: HbA1c correlates with blood sugar levels but does not show a correlation with lipid profiles.Keywords: HBA1C, lipid profile, blood sugar, type 2 diabetes mellitusCorrespondence:Endy Julianto. Department of Parasitology, Faculty of Medicine, Methodist University, Medan.Indonesian Journal of Medicine (2017), 2(3): 207-212https://doi.org/10.26911/theijmed.2017.02.03.08

The Relationship between Social Economic Levels and Anemia Events in Pregnant Women in Glugur Darat Health Center Noviyanti, Berliana; Simanjuntak, Harry C; Hutasoit, Eka Samuel P; Silitonga, Hendrika A; Julianto, Endy
Journal of Maternal and Child Health Vol 4, No 6 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Anemia is a condition where the hemoglobin level in the blood was lower than normal. Anemia diagnosed when the hemoglobin level was <11 gr / dl in the first and third trimesters or <10.5 gr% in the second trimester in pregnant women. WHO stated in 2010 that 40% of the causes of maternal mortality in developing countries were associated with anemia in pregnancy. Based on the Riskesdas (Basic Health Research) in 2013, the prevalence of anemia in pregnant women in Indonesia was 37.1%. One of the factors that influenced the incidence of anemia in pregnant women was the socio-economic level. The purpose of this study was to determine the relationship between socio-economic level and the incidence of anemia in pregnant women at the Glugur Darat Health Center.Subjects and Method: This was an analytical study with a cross sectional approach, conducted at Glugur Darat health center, Medan in 2018. Total 65 pregnant women were selected by consecutive sampling. The independent were the education level, job status, income level. The dependent variable was the incidence of anemia in pregnant women. Data obtained by a set of questionnaire. The data analysis was conducted using Chi Square test. Results: As many as 40 pregnant women (61.5%) had anemia and 25 (38.5%) who were not anemic. 34 people (85.0%) among pregnant women with anemia was in the non-risk group, and 22 people in the Multi-gravida group (55.0%), 16 (40.0%) people in the Primipara group, 27 people (67.5%) in Trimester gestational age III. As many as 28 people (70.0%) had secondary education. Based on occupational 31 people (77.5%) was not working, 19 people (47.5%) had medium income.Conclusion: There was no significant relationship between the level of education, occupational status, and income level with the incidence of anemia in pregnant women.Keywords: Education, Employment, Income, Anemia, Pregnant Women.Correspondence: Berliana Noviyanti. Faculty of Medicine, Universitas Methodist Indonesia, Medan, Sumatra Utara. Email: berliana.noviyanti55@gmail.com.Journal of Maternal and Child Health (2019), 4(6): 48-56https://doi.org/10.26911/thejmch.2019.04.06.05

THE EFFECTS OF ETHANOL EXTRACT AND ETHYL ACETATE FRACTIONATION OF SECHIUM EDULE JACQ. SWARTZ ON TRIGLYCERIDE LEVELS IN MALE RATS WITH TYPE 2 DIABETES MELLITUS Siahaan, Jekson Martiar; Julianto, Endy; Silitonga, Hendrika Andriana
Indonesian Journal of Medicine Vol 4, No 4 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: The prevalence of diabetes mellitus (DM) from year to year is increasing. Hyperglycemia that occurs in DM is caused by oxidative stress that damages pancreatic ? cells. This situation can be controlled with synthetic hypoglycemic drugs, but it requires high medical costs. Therefore, alternative therapies that are easily available, relatively inexpensive, have potential anti-hypoglycemia and anti-cholesterolemia which is found in conjoined flasks (Sechium edule (Jacq.) Swartz) which contains flavonoids are needed. The purpose of this study was to analyze the effectiveness of ethanol extract and fractionation of ethyl acetate extracts of Sami (pumpkin) (Sechium edule (Jacq.) Swartz) as anti-hipoglycemia and anti-hypertriglycerides in white male wistar rats (Rattus novergius sp.) induced by STZ-NA-HFDD.Subjects and Method: A randomized controlled trial was conducted to assess the effectiveness of ethanol extract and fractionation of pumpkin fruit ethyl acetate extract. The sample included white male wistar rats (Rattus novergius sp.) Hyperglycemia induced by STZ-NA-HFD. The dependent variable was triglyceride levels. The independent variables were administration of ethanol extract and fractionation of pumpkin fruit ethyl acetate extract.Results: Ethyl acetate fraction 45 mg/kgBW better reduce triglyceride levels but statistically does not have significant differences between groups.Conclusion: The group that received Metformin and the group that was given ethanol extract 45 mg/kgBW had lower triglyceride levels compared to the other therapy and control groups.Keywords: Hipertrigliseridemia, diabetes mellitus, STZ-NA-HFDCorrespondence: Jekson Martiar Siahaan. Department of Physiology, Faculty of Medicine, Universitas Methodist Indonesia. Jl. Setia Budi Pasar II Tj. Sari, Medan 20132, North Sumatera. Email: Jekson.siahaansked@gmail.comIndonesian Journal of Medicine (2019), 4(4): 371-375https://doi.org/10.26911/theijmed.2019.04.04.10

The Effectiveness of Albendazole-Levamisole and Mebendazole-Levamisole on the Intensity of Trichuris trichiura Infection in Elementary School Children Anto, Endy Juli; Siahaan, Jekson Martiar; Silitonga, Hendrika Andriana
Indonesian Journal of Medicine Vol 5, No 1 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Trichuris trichiura worm infecÂtion is still a major public health problem in IndoÂÂnesia, especially in peripheral areas. Until now, the search for antihelmintic combinations that have a high healing ability against T. triÂchiÂura infections and in the search for truly effective wormÂing is still being done. Albendazole and Mebendazole single doses still show limited efÂfiÂcaÂcy in the treatment of T. trichuria worms. The combination of Albendazole with Levamisol can increase effectiveness, but this combination still needs further investigation. Based on that fact, it is necessary to study the effectiveness compaÂrison of the degree of infection intensity between the treatment of Albendazol-Levamisol and MeÂbenÂdazol-Levamisol against T. trichiura.Subjects and Method: A double blind ranÂdomized control trial was conducted at the State Elementary School in Medan, North Sumatera, from April to October 2019. A sample of 60 children was selected for this study. The depenÂdent variable was the number of eggs decreased, the cure rate, and side effects. The independent variables were Albendazole 400 mg-Levamisol 50 mg/ 100 mg and Mebendazole 500 mg-Levamisol 50 mg/100 mg. The stools of elementary school children were examined using the Kato-Katz method to find eggs of T. trichiura infection. Data analysis was performed using the Chi square test. Results: Samples in the Albendazol-Levamisol and Mebendazol-Levamisol groups were 30 children, respectively. Children infected with T. trichiura consisted of 58 children of mild inÂtensity (96.7%) and 2 children of moderate inteÂnsity (3.3%). On the results of stool examination, a significant difference in the number of eggs decreased in the two groups was obtained (p <0.001) and 96.7% was the cure rate for T. trichiura infection in the two groups of AlbenÂdazol-Levamisol and Mebendazol-Levamisol. In this study, there were no significant differences in side effects in the two treatment groups.Conclusion: Treatment of T. trichiura infection with single doses of Albendazol-Levamisol and Mebendazol-Levamisol showed that there were sigÂnificant differences in the Number of DÂecreased Eggs. Meanwhile, for the cure rate, there was no difference between the Albendazol-Levamisol and Mebendazol-Levamisol groups.Keywords: T. trichiura, Albendazole-Levamisol, Mebendazole-LevamisolCorrespondence:Â Endy Juli Anto. Department of Parasitology, Faculty of Medicine, Universitas Methodist InÂdonesia, Medan, Indonesia. Email: dr.endyÂjulianto@gmail.com. Mobile: +62-823 6766-7575Indonesian Journal of Medicine (2020), 5(1): 17-23https://doi.org/10.26911/theijmed.2020.05.01.03

The Effects of Ethanol Extract, Chayote (Sechium Edule (Jacq.) Swartz) Fraction and Juice on the High-density Lipoprotein Level in Male White Mice Siahaan, Jekson Martiar; Anto, Endy Juli; Fauzi, Tengku Muhammad
Indonesian Journal of Medicine Vol 6, No 2 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Cholesterol imbalance occurs in Diabetes Mellitus, where high-density lipoprotein (HDL) levels are low and low-density lipoprotein (LDL) increases, where this imbalance results in the appearance of atherosclerosis. HDL has antiarterosclerotic potential so it needs to be targeted for therapy. One of the bioactive compounds that have this effect is found in chayote (Sechium edule (Jacq.) Swartz). This study aimed to examine the effects of ethanol extract, Chayote (Sechium Edule (Jacq.) Swartz) fraction and juice on the hdl level in male white miceSubjects and Method: A randomized controlled trial study was conducted to test HDL level in 54 male white rats of the Wistar strain (Rattus novergius sp.) after received ethanol extract, Chayote (Sechium Edule (Jacq.) Swartz) fraction and juice. The dependent variable was the HDL level. The independent variable was the variation in the dose of ethanol extract, fraction and Sechium edule (Jacq.) Swartz Juice. The data were analyzed using Anova test.Results: The treatment group induced by Streptozotocin 50 mg / kgBW + nicotinamide (120 mg/kgBW) + HFD and obtained ethanol extract of chayote fruit 150 mg / kgBW, orally had the highest average HDL levels compared to other groups (Mean = 17.31; SD = 3.14).Conclusion: The ethanol solvent found in the ethanol extract is better because it attracts biaoctive compounds so that it has a better effect than the ethyl acetate fraction and the n-hexane fraction.Conclusion: The ethanol solvent found in the ethanol extract is better because it attracts biaoctive compounds so that it has a better effect than the ethyl acetate fraction and the n-hexane fraction.Keywords: HDL, Flavonoid, Sechium edule (Jacq.) SwartzCorrespondence: Jekson Martiar Siahaan. Department of Physiology, Faculty of Medicine, Universitas Methodist Indonesia. Jl. Setia Budi Pasar II Tj. Sari, Medan 20132, North Sumatera. Email: jekson.siahaan.sked@gmail.comIndonesian Journal of Medicine (2021), 06(02): 145-151https://doi.org/10.26911/theijmed.2021.06.02.03

Perbandingan Efi kasi dan Efek Samping Antara Albendazol, Albendazol-Levamisol dan Mebendazol-Levamisol Terhadap Infeksi Soil-Transmitted Helminths pada Anak Usia Sekolah Dasar Negeri Kabupaten Deli Serdang Endy Julianto
JURNAL ILMU KEFARMASIAN INDONESIA Vol 15 No 2 (2017): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Intestinal worm infection in particular of Soil Transmitted Helminth is still a global problem with high prevalence on the tropic and subtropic regions including Indonesia especially in the rural community. Double Blind Randomized Trial that started from April to June 2015 in which the samples are collected from public elementary school children on the Deli Serdang Regency to compare the effectivity and side effect of STH infection treatment by using Albendazole 400 mg, Albendazole 400 mg-Levamisol 50 mg/100 mg, Mebendazole 500 mg-Levamisol 50 mg/100 mg. The samples of Albendazole, Albendazole-Levamisol and Mebendazole-Levamisol groups consist of 60 children in each group in which the ones that have STH infection are Ascariasis 92 children 51.11%, Trichuriasis 37 children 20.55%, and mixed infection 51 children 28.33%. In this research, researcher doesn’t found hookworm infection in any of the groups. From the result ofstool examination, researcher found 100% of cure rate for A. lumbricoides infection on all groups, cure rate of T. trichiura infection 66.7%, 94.7%, 92.3% for each Albendazole, Albendazole-Levamisol, and Mebendazole-Levamisol groups meanwhile cure rate for mixed infection are 28.6%, 85.7%, and 66.7% for each Albendazole, Albendazole-Levamisoland Mebendazole- Levamisol groups. For mild T.trichiura infection treatment with singledose of Albendazole-Levamisolgroup is better than both of Albendazole and Mebendazole- Levamisole groups (p=0.01). In this research, researcher found nausea and diarrhea as treatment of side effect and no signifi cant difference of side effect in all groups of treatment.

PENYULUHAN DAMPAK INFEKSI HIV AIDS KEPADA MASYARAKAT DESA LUMBAN PEA TIMUR, KABUPATEN TOBA Endy Juli Anto; Dwi L. D. S. Siahaan; Evirosa J. Simanjuntak; Inda M. Sinaga; Faskanita M. Nadapdap; Frengky S. Manullang; Novrina Situmorang; Jimmy Jimmy; Juliyanti Juliyanti; Laura P. S. Tambunan; Widjaya Taufik Tiji; Alex M. Lumbanraja; Jadeny Sinatra; Alexander P. Marpaung; Elizabeth S. Girsang; Ivonne R. V. O Situmeang; Jerry Tobing; Caroline Koswara; Helmida Gultom; Jeffrey
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 2 No 1 (2022): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Community Service (PkM) is carried out by the Faculty of Medicine Universitas Methodist Indonesia by providing counselling the effect of HIV Infections and AIDS. PkM was held on 8-11 June 2022 at Lumban Pea Timur, Balige,Toba District, North Sumatera. The method used is to provide counselling/lectures and provide motivation, then followed by question and answer to obtain results and solutions as a form of problem’s solving and obstacles faced. The results of PkM with counselling are very effective considering that there are still many people who do not get information about HIV infections and AIDS. With this counselling, the public becomes aware of the HIV_AIDS Infections problem. Thus, it is hoped that the people of Lumban Pea Timur will aware and know how to prevent their community from HIV-AIDS Infections.

GAMBARAN TINGKAT PENGETAHUAN IBU HAMIL TENTANG PEMBERIAN ASI EKSKLUSIF DALAM PEMENUHAN GIZI BAYI UMUR 0-6 BULAN Elizabeth Septianur Girsang; Dina Keumala Sari; Endy Juli Anto
Majalah Ilmiah METHODA Vol. 8 No. 1 (2018): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol8No1.pp96-102

Background. Exclusive breastfeeding has many benefits for babies, including babies getting a complete source of nutrition, babies protected from gastrointestinal infections, increasing immunity, reducing death rates caused by various diseases, besides breastfeeding can increase intelligence including spiritual intelligence , maintaining the growth and development of the baby's brain. The provision of ASI has not been utilized optimally by mothers, this is due to several factors including the low level of understanding of exclusive breastfeeding due to lack of information or knowledge possessed by mothers regarding all values plus nutrients and benefits contained in breast milk. This study aims to describe the knowledge of pregnant women about exclusive breastfeeding in fulfilling nutrition for infants aged 0-6 months in Tanjung Rejo Village, Medan Sunggal Subdistrict, 2017. Methods. This study used a descriptive research method with a cross sectional design. This research was conducted on 31 October 2016-20 July 2017. The sample size was 63 people using the Total Sampling method. Methods of collecting data using a questionnaire. Processing data by editing, coding, entry, cleaning and tabulating. Data analysis using univariate analysis. Result. The results of the study showed that there were 18 respondents (28.6%) good levels of knowledge, there were enough 40 people (63.5%) and less than 5 people (7.9%). Summary. Respondents knowledge about level of knowledge of giving the majority of exclusive breastfeeding is quite good.

GAMBARAN KADAR HBA1C PADA PENDERITA DIABETES MELITUS DI KLINIK DIABETES DHARMA MEDAN Thomas Silangit; Endy Juli Anto
Majalah Ilmiah METHODA Vol. 8 No. 1 (2018): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol8No1.pp103-107

Background. Type 2 diabetes mellitus (T2DM) is something that cannot be stated in one clear and concise answer but in general it can be said as a collection of anatomic and chemical problems resulting from a number of factors which obtain absolute or relative insulin deficiency and impaired insulin function. Insulin is a hormone which consists of a series of amino acids, produced by beta cells of the pancreas gland. Under normal circumstances, if there is beta cell stimulation, insulin is synthesized and then secreted into the blood according to the body's needs for the regulation of blood glucose. The glycosylated hemoglobin test, also known as glycohaemoglobin, or glycosylated haemoglobin (HbA1c), is a method used to assess the effect of changes in therapy 8-12 weeks earlier. The purpose of this study was to determine the description of HbA1c levels in the Medan Diabetes Dharma Clinic in 2016-2017 Methods. This study used a descriptive research method with a cross sectional design. This research was conducted in 2016-2017 at the Diabetes Dharma Clinic in Medan. By using total sampling technique, with a sample of 200 patients who have met the criteria. Data is collected by retrieving data from medical records that perform HbA1c checks, then processing and analyzing data. Result. Examination of the highest frequency of HbA1c levels in the age group> 40 years was 180 people (90%). Based on gender, the frequency is more for men, which is 121 people (60%) compared to women, which is 79 people (39.5%). The proportion of the biggest sufferers of diabetes mellitus is 181 people (90.5%) with HbA1c levels of more than 6.4%. The mean level of HbA1c values in patients with diabetes mellitus was 9.295% (2.3) and the highest value was 18.3% and the lowest value was 5.4%. Summary. In this study that T2DM increased at the age above 40 years and the frequency of men was more than women. HbA1c levels at the Diabetes Dharma Clinic in Medan are still uncontrolled.

PENYULUHAN MANFAAT IMUNISASI DASAR KEPADA MASYARAKAT DESA AJIJULU, KABUPATEN KARO Endy Juli Anto; Eka Samuel P. Hutasoit; Surjadi Rimbun; Inda M. Sinaga; Frengky S. Manullang; Novrina Situmorang; Widjaya Taufik Tiji; Ivonne Ruth Vitamaya Oishi Situmeang; Ronald T. H. Tambunan; Evirosa J. Simanjuntak; Larasaty Anjany; Alfri Yoganta S. Kembaren
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 1 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No1.pp1-5

Community Service carried out by the Faculty of Medicine at the Universitas Methodist Indonesia by providing counseling about the benefits of basic immunization. Community Service was held 14-16 April 2023 in Ajijulu Timur Village, Tigapanah District, Karo Regency, North Sumatra. The counseling method used is by giving lectures, discussions and providing motivation. Question and answer discussions were carried out with the aim of gaining understanding, understanding and solutions as a form of solving problems and constraints faced by the local community. The results of this community service counseling and outreach are very effective considering that there are still many people who do not receive information about the benefits of immunization. With this counseling, the community becomes more aware of the importance of basic immunization. It is hoped that the people of Ajijulu will become more responsive and know how important this basic immunization is for infants, children and adolescents.

Co-Authors Alex M. Lumbanraja Alexander P. Marpaung Alfri Yoganta S. Kembaren Bintang Andika Panjaitan Budi Darmanta Sembiring Caroline Koswara Depari, A. A. Dina Keumala Sari Dwi L. D. S. Siahaan Eka Samuel P. Hutasoit Elizabeth S. Girsang Elizabeth Septianur Girsang Estela Salomina Momot Evirosa J. Simanjuntak Faskanita M. Nadapdap Fauzi, Tengku Muhammad Frengky S. Manullang Gani, Endang Haryanti Girsang, Elizabeth Septianur Hadyanto Lim Helmida Gultom Hendrika Adriana Silitonga Hutasoit, Eka Samuel P Hutasoit, Eka Samuel P Inda M. Sinaga Ivonne R. V. O Situmeang Ivonne Ruth Vitamaya Oishi Situmeang Jadeny Sinatra Jeffrey Jekson M. Siahaan Jekson Martiar Siahaan Jeremia Simanjuntak Jerry Tobing Jimmy Jimmy Juli Jamnasi Juliyanti Juliyanti Kerin Repaskatri Sihaloho Kesia Sijabat Larasaty Anjany Laura P. S. Tambunan Lovian Nauli Sihaloho Mega Wijaya Menang Bastanta Tarigan Michael Sabatino Sitompul Mikael Sembiring Noviyanti, Berliana Noviyanti, Berliana Novrina Situmorang Ronald T. H. Tambunan Ronald Tunggul Hotmarojahan Tambunan Sari, Dina Keumala Siahaan, Jekson Martiar Silangit, Thomas Silitonga, Hendrika A Silitonga, Hendrika A Silitonga, Hendrika Andriana Simanjuntak, Harry C Simanjuntak, Harry C Sumihar Maurist Rantos Pasaribu Surjadi Rimbun Tengku Muhammad Fauzi Thomas Silangit Widjaya Taufik Tiji Widya Dayanti Feronika Manik

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